A new study has failed to replicate a controversial experiment suggesting the existence of precognition, thereby debunking claims of psychic ability. The researchers, led by Stuart Ritchie, found no statistically significant effects in their attempts to replicate the results.
Researchers at the University of Kentucky have identified a key protein interaction that promotes metastasis in triple-negative breast cancer. Snail interacts with G9a to suppress E-cadherin expression, which is critical for cell adhesion and preventing tumor spread.
Scientists discover new leopard frog species in New York City's Staten Island ponds and marshes, identified through DNA analysis. The unusual species has a distinct genetic lineage, separate from other leopard frog species in the region.
A two-year Duke University study found that over half of patients had experienced sexual or physical abuse in their lifetime, leading to worse medical outcomes and poorer health-related behaviors. Childhood trauma was also associated with instances of unprotected sex, missing antiretroviral medications, and recent emergency room visits.
The US GEOTRACES initiative will conduct a grand-scale, coordinated experiment in the Arctic Ocean to better understand climate change impacts on ecosystems and geochemical cycles. The project aims to establish a baseline for future measurements and inform feedback mechanisms for Arctic change.
Goblet cells, previously thought to only secrete mucus, have been found to chaperone food antigens in the intestine, connecting them to dendritic cells. This discovery provides new insights into intestinal immunity and potential targets for therapies against inflammatory bowel disease, celiac disease, and food allergies.
The number of US deaths from gastroenteritis increased by 10,000 over eight years, with adults over 65 accounting for most deaths. C. difficile and norovirus were the top infectious causes, with a five-fold increase in C. difficile deaths.
A study of over 6,600 US mothers found that giving birth to unusually small infants doubles the risk of ischemic heart disease. The correlation was independent of other factors, suggesting that such pregnancies may induce cardiovascular changes and be an early risk factor for heart disease.
Researchers sequenced DNA from cancer cells in patients with myelodysplastic syndromes who later developed leukemia, finding that the disease is an early form of cancer. The study suggests that targeted cancer drugs should be aimed at mutations that develop early in the disease.
Spanish scientists have confirmed a clear relationship between androgenetic alopecia and benign prostate hyperplasia, with men experiencing premature baldness at higher risk for BPH. The study, published in the Journal of the American Academy of Dermatology, found an association between hormone levels and prostate volume.
The discovery of fossils from two caves in south-west China reveals a previously unknown Stone Age people with unusual anatomical features. Dated to 14,500-11,500 years old, these individuals may represent a previously unknown species or early migration of modern humans out of Africa.
Researchers found significant health and ecosystem implications from coal-tar-based sealcoats, which release PAHs detrimental to human and ecosystem health. The study recommends avoiding coal-tar-based sealcoats in favor of asphalt-based ones or no sealcoat at all.
Two new NASA LRO videos reveal the moon's evolutionary history, exploring how it came to appear today. The 'Evolution of the Moon' video explains the moon's formation from a giant ball of magma and its subsequent impact that formed the South Pole-Aitken Basin.
Researchers have discovered that Japanese honeybees use a novel defense mechanism when threatened by Asian giant hornets, creating a 'hot defensive bee ball' to cook the hornet. This behavior differs from European honeybees and is associated with increased neural activity in higher brain centers.
A recent study by the Norwegian Institute of Public Health found that silver nanoparticles can suppress cellular growth and multiplication, causing cell death depending on concentration and duration of exposure. Titanium dioxide nanoparticles also caused DNA damage but with weaker effects.
The study reveals that silicon-carbon nanocomposite electrodes can withstand repeated use and charging cycles without significant degradation. The electrodes' expansion and contraction caused by lithium ion flow are more even and less prone to imperfections, leading to improved battery performance and potential for longer lifetimes.
Researchers found gene mutations in DNMT3A and NPM1, as well as translocations, associated with improved patient outcomes when treated with higher doses of daunorubicin chemotherapy. This discovery could help physicians tailor treatment plans for individual patients.
A scientific team reports that a 'balanced harvest' can achieve productive fisheries while conserving environmental factors, according to the journal Science paper. This approach maximizes production and minimizes ecological effects by targeting multiple species and sizes.
University of Michigan researchers lead a longitudinal study on concussions and sports, aiming to create unprecedented data on brain health. The study will follow athletes through their lifetime, monitoring the long-term effects of head injuries.
Researchers analyzed fatty acid composition and DNA analysis to identify the source of US-grown pine nuts. Most samples found to be mixtures of different species, but combining these methods didn't definitively link to 'pine mouth',
A study published in JAMA found that the number of stroke victims transported via ambulance has remained relatively static over the years, emphasizing the importance of recognizing stroke symptoms and calling 911. Early treatment is possible with effective drugs and surgeries that can minimize brain damage from a stroke.
Princeton scientists have identified unique neural activity sequences in the brain's posterior parietal cortex that help form short-term memories used for decision-making. These sequences correspond to whether a mouse turns left or right in a maze, allowing researchers to predict its future actions.
Researchers call for ob-gyns to evaluate patients' exposure to environmental chemicals, provide education, and advocate for policy change to reduce toxic exposures. The human reproductive system is vulnerable to biological changes caused by chemicals during critical periods of development.
Researchers identified a gene mutation associated with chronic neuroblastoma that typically affects adolescents and young adults. The discovery provides clues about the genetic basis of treatment outcome and age at diagnosis.
Researchers found that healthcare provider attitudes toward vaccinating young males against HPV can influence the implementation of new guidelines. Targeted education on HPV's association with certain cancers in men is crucial for achieving vaccination goals.
The Spine Patient Outcomes Research Trial (SPORT) found surgical treatment significantly favored outcomes for IDH, DS, and LSS, while vitamin D deficiency is critical to musculoskeletal health. A new study urges orthopaedic surgeons to proactively diagnose and treat vitamin D deficiency, which can improve treatment results for various ...
Researchers have discovered a novel link between lithium and body clocks in treating bipolar disorder. Lithium salts increase the strength of clock rhythms, which may lead to more effective treatments with fewer side effects.
African Americans in Georgia have poorer survival rates from cancer compared to national averages, with racial disparities widening rural areas. The study found that MIRs were higher for African Americans than whites across all cancer sites, particularly prostate, cervical, and oral cancers.
A new endoscopic procedure, transgastric necrosectomy, has been shown to reduce major complications and death in patients with infected severe pancreatitis compared to traditional surgical methods. The study found that the procedure resulted in lower proinflammatory response and reduced rates of multiple organ failure.
A study by Jessi Witt and coauthors found that visual illusions can improve sports performance, particularly in free throws. By projecting a ring of circles around the basket, players sank more putts when the hole looked bigger—about 10 percent more.
Researchers call for linking guideline development and policy development to improve global health systems guidance. A panel can ensure output is used for both policy and guidance development, addressing complexity of health systems and contexts.
Researchers have discovered that administering FTY720, an oral drug shown promise for multiple sclerosis, significantly improves motor function recovery in mice with spinal cord injuries. The study suggests targeting sphingosine 1-phosphate receptors may be a new avenue to counteract the degeneration of the spinal cord in human SCI.
Recent study in Molecular Ecology reveals spotted hyenas exhibit strong kinship relationships, affected by resource reduction. The San Diego Zoo Global Wildlife Conservancy's conservation efforts focus on understanding and conserving these social systems.
A new technique published in JoVE uses MRI-guided microbubbles and focused ultrasound to disrupt the blood-brain barrier, potentially opening new treatment avenues for devastating conditions like Alzheimer's and brain cancers. The method is safer than current methods, which can leave large areas of the barrier exposed to toxins.
A major study led by the University of Adelaide found that women who had one prior cesarean can lower the risk of death and serious complications for their next baby. Infants born to these women had a significantly lower risk of serious complications compared to those born after a vaginal birth following a prior cesarean.
Women farmers produce a lower yield on their crops than male farmers by an average of 25 percent. A recent report shows differences in yield in the same household, with female farmers facing restrictions on access to labor and basic farm inputs.
A study published in the Journal of Neuroscience shows that EpoD prevents further neurological damage and improves cognitive performance in a mouse model of Alzheimer's disease. The drug acts by stabilizing microtubules, potentially improving nerve-cell function in AD and other diseases.
Tropical Cyclone Lua has strengthened to a minimum tropical storm with maximum sustained winds near 35 knots, while System 96P is getting organized in the Southern Pacific Ocean. Both systems are affecting coastal areas in northern Australia and are expected to bring heavy rainfall, gusty winds, and rough surf.
A cancer compound called epothilone D has been found to slow neurological damage and improve memory in a mouse model of Alzheimer's disease. The treatment prevented tau tangle formation and improved learning and memory tests, suggesting potential therapeutic benefits.
A recent study discovered an association between the ATRX gene mutation and age at diagnosis in children with advanced-stage neuroblastoma. The research found that ATRX mutations were more common in adolescents and young adults, suggesting a potential molecular marker and therapeutic target for this age group.
A UK study published in PLOS Medicine found that uterine rupture is rare but increases with the number of previous caesarean deliveries. Women planning vaginal delivery after a previous caesarean section are at higher risk, especially if labor is induced or has a short interval since the last surgery.
Two large meta-analyses found a genetic variation in the interleukin-6 receptor associated with lower levels of inflammatory biomarkers and reduced coronary heart disease risk. A single-nucleotide polymorphism was linked to effects consistent with known benefits of IL6R blockade in patients with rheumatoid arthritis.
A new study reveals China's groundwater irrigation system is responsible for releasing over 30 million tonnes of CO2 into the atmosphere every year. This significant pollution is caused by the energy needed to pump water from underground, with some areas requiring pumps that run for miles.
A NASA experiment aboard the International Space Station has demonstrated remotely controlled robots can perform precise satellite-servicing tasks in space, marking a milestone in technology test bed use. The project is expected to reduce risks and encourage future robotic servicing missions, paving the way for satellite repair, refuel...
Researchers found that lowering the HbA1c cutoff from 6.4% to 5.7% increases the health benefits of preventive interventions, while also being cost-effective with a higher threshold.
JBEI researchers have engineered Escherichia coli bacteria to generate significant quantities of methyl ketone compounds from glucose, which yielded high cetane numbers comparable to gasoline. The findings add flexibility and options for the biofuels industry, with potential applications in producing advanced biofuels.
A study found that hospitals in Ontario with higher spending on intensive care and specialists had lower death rates, hospital readmissions, and better quality of care for severely ill patients. Higher-spending hospitals also saw longer lengths of stay and more medical specialist visits.
Gene Kritsky will give the Entomology Founders' Memorial Award lecture at Entomology 2012, honoring Charles Darwin's theory of evolution by natural selection. Dr. Kritsky's research has significantly contributed to understanding periodical cicadas and apiculture.
A recent study found that the protein Mer resides in the nucleus of leukemia cells, suggesting it may influence gene expression and contribute to cancer development. This discovery opens up new avenues for targeted treatments and potentially more accurate diagnoses.
Researchers at the Catholic University of Rome found that high concentrations of NF-kB cause degeneration of intervertebral discs, leading to chronic low back pain. They developed an experimental drug, NBD peptide, to inhibit NF-kB and tested its success in mice.
The Optics Express Focus Issue on Modular Ultrafast Lasers showcases state-of-the-art developments in femtosecond lasers, enabling new applications in biology, medicine, chemistry, and energy research. Key findings include the generation of broad-bandwidth frequency combs for precision metrology and spectroscopy.
Stephanie Turner Chen has received the Larry Sandler Memorial Award for her research on the detection of carbon dioxide in fruit flies and mosquitoes. Her work provides a novel approach to mosquito control, revealing odors that inhibit their ability to detect carbon dioxide.
Scientists have recorded unprecedented deformation within Santorini's caldera, with movement of up to nine centimeters between GPS stations. The volcano's magma chamber has expanded by 14 million cubic meters since January, raising concerns about a potential eruption.
Scientists at UC San Diego School of Medicine developed a new strategy for faster anticancer drug discovery by analyzing the genetic pathway of disease. They identified Peruvoside, a cardiac glycoside, as a potential treatment for prostate cancer with minimal side effects.
A new study from Rice University and Baylor College of Medicine has developed a computer program called EpiPredictor to rapidly identify genes targeted by epigenetic proteins. The program, which was funded in part by the Cancer Prevention Research Institute of Texas, shows promise for speeding up research in cancer epigenetics.
Cartilage transplant tissue can now be stored for up to 63 days, compared to 28 days previously, using a new method developed by researchers at the University of Missouri. This increase in storage time is expected to greatly improve the success rate of joint grafting procedures.
The publication brings together the latest knowledge on eastern big-eared bats, a group of species at risk due to habitat loss and environmental contaminants. The research provides guidance on securing or improving habitat for these bats, including discussions of conservation and management strategies.
A genetic study found that targeting the interleukin-6 receptor (IL6R) signalling pathway could be an effective way to combat heart disease. The research, led by the University of Cambridge, discovered a genetic variant that reduces the risk of coronary heart disease.
Aaron E. Carroll, a renowned health policy expert, will provide insight into the political aspects of health care via The JAMA Forum, analyzing presidential campaign proposals and Supreme Court decisions.
A study published in PLOS ONE found that dietary trans fatty acids are associated with irritability and aggression in both men and women of all ages. The research, which analyzed data from nearly 1,000 adults, suggests a strong link between trans fat consumption and aggressive behaviors.