A study published in the International Journal of Food Microbiology identified Cronobacter sakazakii's genetic survival strategies, revealing a higher prevalence of genes associated with DNA recombination and desiccation resistance. The findings suggest that accessary genes may enable the pathogen to persist in various environments.
Children from ethnic minority backgrounds and those living in areas with higher levels of child poverty were found to be more likely to die in intensive care. The study reveals persistent inequalities in critical care outcomes for children, even after admission, and emphasizes the need for urgent action to reduce child poverty and impr...
A team of researchers developed a molecular probe that detects sugar consumption in microbes, revealing the role of microorganisms in breaking down ocean sugars. The study provides new insights into glycan cycling across ecosystems and sheds light on the global carbon cycle.
Researchers at Stevens Institute of Technology have developed a groundbreaking formula that describes the relationship between a quantum object's wave-ness and particle-ness. This breakthrough enables more precise imaging techniques, such as quantum imaging with undetected photons, which can accurately map the shape of an object even i...
Researchers found that drones can suppress common reed invasions with over 99% effectiveness, using a single targeted herbicide application. This method provides convenient access and reduces risks of trampling or disturbance, while also minimizing off-target impacts and promoting native vegetation recovery.
Researchers at Sutter Health tested the performance of the American Heart Association's PREVENT equations in diverse Asian and Hispanic subgroups, showing accurate prediction of cardiovascular disease, atherosclerotic CVD, and heart failure events. The study findings aim to improve cardiovascular healthcare for all populations.
A new study has found that residents' anxiety and stress about climate change is associated with increased disaster preparedness behaviors in Lake County, California. The research suggests that a certain level of anxiety may be adaptive, motivating important disaster preparedness actions.
Scientists at the University of Birmingham have developed a method to coat Hepatic Progenitor Cells (HPCs) with natural sugars, making them stickier and increasing their ability to repair liver tissues. The coating does not harm the cells or stop them from working properly.
Researchers developed a low-radiation dose imaging protocol and a deep learning model to generate vital blood flow maps for assessing stroke patients. The innovation slashes radiation exposure by over 80% compared to current methods, making stroke diagnosis safer and more accessible.
Eleven leading education research organizations call on the US Department of Education to finalize the Civil Rights Data Collection (CRDC) for the 2025-26 school year, citing a critically short timeline. The groups warn that final approval could push past September, creating logistical challenges for school districts.
The Chan Zuckerberg Initiative's latest AI model, GREmLN, is designed to predict and understand how genes interact within cells. It focuses on the molecular logic that defines gene behavior, allowing researchers to track critical changes pinpointing the earliest signs of disease.
A new study reveals that early-life competition in parasitoid flies can have lasting effects on their growth and survival. The research found that larvae competing for resources inside a single host lead to reduced survival, smaller pupae, and ultimately smaller adult flies.
A large medical record study found that receiving six or more gabapentin prescriptions for low back pain significantly increases the risk of developing dementia (29% higher) and mild cognitive impairment (85% higher). Risks are particularly high among 18-64 year olds, with no age group considered safe from increased risks.
A new study published in the Journal of Hepatology shows that durvalumab plus GemCis significantly improves overall survival for patients with advanced biliary tract cancer. The three-year follow-up analysis found that over twice as many participants treated with durvalumab plus GemCis remained alive compared to those treated with a pl...
Researchers have identified a new strain of orthoreovirus in an Everglades short-tailed shrew, which is believed to be transmissible to humans. The discovery was made possible by the cat, Pepper, whose hunting prowess led to the finding of the virus.
A new study by University College London found that nearly 58% of women who had given birth in the last year were not using contraception two months later, despite the risk of back-to-back pregnancies. Women who received high-quality contraceptive advice were more likely to use contraception sooner after giving birth.
A study from The University of Osaka reveals nearly half of patients with extracranial arteriovenous malformations carry mutations in the RAS/RAF/MAPK signaling pathway. These mutations were linked to abnormal vascular morphology and were frequently detected in younger female patients.
A new study estimates US vacation renters waste $2.3 billion worth of food each year due to grocery and leftovers going uneaten. The average nightly rental fee comes with a 5.1% surcharge for wasted food, equivalent to an additional lodging tax.
Researchers discovered a cancer signaling pathway's role in regulating the blood-retina barrier, potentially damaging protective mechanisms. The study also identified a new gene linked to inherited eye condition FEVR, highlighting the need for further investigation into vascular disorders.
A new study by the University of Cambridge found that seaside and blue-colored places are more likely to evoke feelings of nostalgia in people. The research suggests that these environments have visual properties that contribute to positive emotions, including 'fractal property' and high contrast.
A nationwide study of 1,500 US women aged 40-65 found that most continue to experience orgasm at the same frequency and quality as younger peers. The study suggests promoting masturbation among older women may enhance well-being and alleviate menopausal symptoms.
Researchers at MIT developed an implantable device that can store glucagon to counteract hypoglycemia, a life-threatening condition for people with Type 1 diabetes. The device, about the size of a quarter, contains a small reservoir made of 3D-printed polymer and can be triggered remotely or automatically by a sensor.
A new study published in BioScience found that cancer is incredibly rare in turtles, affecting only about 1% of individuals. The research, led by the University of Nottingham, analyzed medical records and necropsies from hundreds of zoo turtles, revealing tumours rarely spread.
Researchers developed a novel electroenzymatic platform enabling efficient non-natural oxidation reactions with high enantiomeric excess, opening a new chapter in biocatalysis for asymmetric synthesis
Researchers estimate 27 million tons of nanoplastics in North Atlantic Ocean, shedding light on the 'paradox of missing plastic'. The discovery highlights the significant amount of plastic debris that has been underestimated and raises concerns about its impact on marine ecosystems.
Scientists have recovered a protein sequence from a fossilized tooth over 20 million years old, revealing new insights into the rhino family tree and its divergence from other species. This ancient find expands the timescale for recoverable evolutionary-informative protein sequences by ten-fold.
A new multi-institutional clinical trial will test zipalertinib, an investigational drug targeting specific EGFR mutations in early-stage non-small cell lung cancer. The goal is to prevent recurrence and improve long-term outcomes for patients with limited treatment options.
Researchers demonstrated a record-breaking long-distance THz wireless transmission of high-definition video over 1.2 km using an astronomical telescope with a quantum-limited superconductor-insulator-superconductor mixer at 500 GHz.
The collaboration aims to increase print quality and consistency for large-format 3D printing, enabling applications in hydroelectric dams, oil and gas industries, and more. ORNL's slicing software and JuggerBot 3D equipment will be refined to process thermosets independently and simultaneously.
A recent study published in Nature reveals that weight loss triggers the breakdown and recycling of fats called lipids, potentially leading to improved health outcomes. Weight loss also clears out senescent cells, which are ageing and damaged cells that accumulate in tissues, reducing inflammation and scarring.
Researchers studied atomic-scale defects in single-crystal IGZO to understand its electronic properties. They found that oxygen vacancies and structural disorder contribute to device instability, but also detected a relationship between crystallinity and subgap states.
A new palladium-loaded a-IGZO catalyst achieved over 91% selectivity when converting CO2 to methanol, leveraging electronic properties of semiconductors. The study demonstrates novel design principles for sustainable catalysis based on electronic structure engineering.
A new approach uses DNA to fabricate targeted 3D nanoscale structures via self-assembly, allowing for complex designs and parallel assembly. The method enables significant time- and cost-savings compared to traditional top-down strategies.
Researchers developed a biomimetic codelivery system to target cancer stem-like cells, vasculogenic mimicry, and the immune microenvironment in triple-negative breast cancer. The treatment inhibits PKM2, suppresses CSC stemness, and reverses EMT, leading to improved therapy outcomes.
A research team developed a novel polyol process-based ruthenium catalyst synthesis method with improved ammonia decomposition performance. The new catalyst demonstrated more than three times higher efficiency compared to conventional catalysts.
Scientists have developed a new class of twistable materials, unlocking unprecedented quantum possibilities. The twist platform can engineer entirely new quantum states, including quantum spin liquids with potential applications in high-temperature superconductivity.
IHMT-15130, a selective BMX inhibitor, demonstrates robust efficacy in preclinical models of cardiac hypertrophy by suppressing inflammation and reversing pathological heart muscle thickening. The compound offers a safer therapeutic window for treating this major cardiovascular disorder.
Researchers developed a soft electroactive polymer eel-like robot that can explore underwater environments with minimal impact on wildlife and fragile structures. The robot uses dielectric elastomer material, enabling it to swim efficiently without causing harm to the environment.
A large prospective study found that a healthy plant-based diet is associated with an 8% lower risk of ulcerative colitis and a 14% lower risk of Crohn’s disease. Fruits and vegetables were identified as key protective factors against inflammatory bowel disease.
Researchers discovered a unique nanostructure in blue shark skin that produces their iconic blue coloration, which also suggests a potential capacity for color change. Tiny changes in guanine crystal spacing can alter the shark's body color to suit its environment.
A new study reveals that Alzheimer's risk genes influence tau buildup and spread in distinct pathways, challenging traditional views of the disease. Four gene types were identified: Network-Aligned Vulnerability and Resilience, and Network-Independent Vulnerability and Resilience.
Researchers developed an AI model that accurately predicts genetic mutations from routine pathology slides, reducing the need for rapid genetic testing by over 40% in lung adenocarcinoma patients. This innovation streamlines clinical decision-making and accelerates access to targeted therapies.
Rising ocean temperatures are causing higher concentrations of toxic algae in Arctic food webs, threatening the nutritional and cultural well-being of Alaska Native communities. Bowhead whales serve as indicators of this change, revealing a critical linkage between warming temperatures and increased bowhead toxicity.
New humanoid surgical robots offer a solution to the growing healthcare labor shortage, allowing for more efficient surgeries and reduced burnout among doctors. By taking on routine tasks, these robots can free up surgeons to focus on more complex procedures.
The study found that acute hepatitis E incidence and Disability-Adjusted Life Years (DALYs) increased globally from 1990 to 2021, with a slight rise in age-standardized rates. The number of incident cases is expected to continue increasing up to 2030.
The study created lightweight, highly deformable materials with tunable mechanical responses using one-DOF mechanisms. These materials enable rapid response switching and reprogramming of force-displacement curves, unlocking new customizable mechanical properties.
Researchers successfully demonstrate Fermi acceleration mechanism with ultracold atoms, unlocking new understanding of cosmic rays behavior. The technology has the potential for high-precision control over particle acceleration and opens new possibilities for investigating phenomena relevant to high-energy astrophysics.
A new study found that live contemporary dance performances trigger brainwave synchrony among audience members, signaling shared engagement. The researchers also discovered that the delta band of slow-frequency brainwaves was responsible for capturing this shared experience.
This review systematically presents China's agricultural biotechnology development, highlighting progress in functional gene discovery and transgenic technologies. The Chinese government has established a regulatory system to ensure safe application of biotech products, with steady annual growth in approved applications, focusing on GM...
At the 2025 American Library Association (ALA) Annual Conference, over 200 attendees engaged with the Sage-sponsored 'Banned Books from the Big Chair' exhibit, discussing book challenges and sharing advice to combat censorship. The event highlighted the number of challenged books and featured award-winning authors.
A pilot study evaluated Nutri, a clinical decision support tool for brief diet counseling in safety-net clinics. PCPs found the system usable and satisfactory, while patients effectively engaged with the intervention.
Researchers developed a novel model optimization algorithm named External Calibration-Assisted Screening (ECA) to enhance the prediction robustness of Near-Infrared Spectroscopy (NIRS) quantitative models. ECA rapidly adapts initial models to new detection environments by calibrating them with externally collected samples.
Researchers have developed an AI-assisted diagnostic system that can estimate bone mineral density in the lumbar spine and femur with high sensitivity and specificity. The system has the potential to transform routine clinical X-rays into a powerful tool for opportunistic screening, enabling earlier detection of osteoporosis.
Researchers found that 7-tesla magnetic fields accelerate demagnetization by 60% while suppressing efficiency by 34%, enabling widespread ultrafast demagnetization in other materials. Elevated temperatures enhance regulatory effects, promising real-world applications in high-speed storage and logic devices.
China experienced severe rainstorms and flooding disasters in 2024, with the Yangtze River basin and southern regions witnessing intense rainfall. The country saw its second-longest heatwave on record, while autumn typhoons displayed exceptional intensity.
A new study found that 4 in 5 adults in the US report some level of loneliness, strongly correlated with poor mental health days and physical health days. Women and Black individuals experienced higher rates of depression and poor mental health days than men and White individuals, respectively.
A study of 679 patients found that longer GLP-1RA treatment, not having diabetes, and higher body fat were associated with better weight reduction. Higher muscle mass and metabolic rate also contributed to successful weight loss in patients with overweight or obesity.
A new study predicts postoperative complications in children up to three days before formal diagnosis using wearable device data and novel metrics related to circadian rhythms. The results show 91% sensitivity and 74% specificity, indicating potential for facilitating faster treatment and care.
A new study found that verbal reaction time can detect sleepiness in older adults, a common safety risk. Voice analysis method reliably detected when someone was speaking versus silent with high accuracy.
Researchers have developed a novel composite electrode that stabilizes reactive oxygen species to facilitate methane activation and C–C bond formation. The study demonstrates superior methane production rates and selectivity, establishing a new paradigm for designing high-activity EOCM catalysts.