The 2025 Glenn Foundation for Medical Research Discovery Awards support groundbreaking research on human aging. Christina Camell, PhD, investigates the role of macrophages in cellular dysfunction during aging, while Elaine Fuchs, PhD, explores epigenetic memories of past inflammatory experiences and their impact on tissue health.
Groundbreaking simulations reveal how black holes create dazzling light shows by material zipping around them. The results could help explain hundreds of faintly luminous objects spotted in the early universe.
A survey of adults in the US found that most people prefer the American Medical Association's (AMA) guidance on vaccine safety over the Centers for Disease Control and Prevention's (CDC), citing concerns about the CDC's recent changes to its website. According to the survey, 35% of Americans would accept the AMA's recommendation, while...
A new study reveals limited data on cognition in individuals with comorbid personality disorder and schizophrenia, leading to unfavourable outcomes. The researchers emphasize the need for further investigation into adapting treatments to support functional recovery.
Dr. Anna Gloyn has been awarded the fifth Transatlantic Alliance Award for her pioneering research on genetic mechanisms of diabetes and precision medicine. Her collaborative work with colleagues across Europe and the United States has significantly advanced our understanding of the genetic basis of diabetes.
Researchers theorize that solar wind storms drove Voyager 2's observations of extreme radiation on Uranus. They suggest a co-rotating interaction region passing through the system could have fueled powerful high-frequency waves.
Researchers found that corporate insiders' trading patterns provided excellent forecasts of future stock performance during the Covid-19 pandemic. Insiders bought undervalued stocks and sold overvalued ones, which predicted market activity. This study highlights the importance of insider trading in times of unprecedented uncertainty.
The special issue highlights novel computational methods for integrating spatial transcriptomics data, improving haplotype assembly and analysis of genomic variation. Several studies present innovative approaches for metagenomic data analyses, long-read sequencing, and genome karyotyping.
Researchers at the University of Plymouth will receive a £2.8 million funding boost to accelerate new treatments for low-grade brain tumors. The center aims to deepen understanding and translate knowledge into life-changing therapies.
Two Russian scientists' conceptual similarities challenge conventional aging views. Their ideas about hyperfunction and elevation remain relevant to modern research. Golubev explores the historical connections between Dilman and Blagosklonny, highlighting their contributions to aging science.
A new study finds that high-narcissism CEOs are more likely to make risky moves, such as acquisitions, when firm performance exceeds expectations. In contrast, low-narcissism CEOs tend to avoid acquisitions during periods of high performance.
A new FAU study reveals significant mental health differences between dark web users and surface web users, with dark web users reporting substantially higher levels of depressive symptoms and paranoid thoughts. The study also found substantial differences in suicidal thoughts, non-suicidal self-injury, and digital self-harm.
Researchers at UT San Antonio have discovered the molecular mechanisms generating electrical oscillations in microtubules, a frequency similar to that observed during brain activity. This discovery could lead to therapies preventing or reversing memory loss and improving neuroplasticity.
Researchers at Okayama University develop a novel photochemical strategy for macrolactonization, transforming hydroxyaldehydes into large ring lactones. The method avoids harsh conditions and multi-step procedures, making it attractive for scaling up synthesis and improving cost-effectiveness.
A recent study published in the American Journal of Preventive Cardiology found that only 13% of US adults with cardiovascular disease met optimal LDL-C management, highlighting significant gaps between guideline recommendations and clinical care. The study suggests actionable steps to improve adherence, including increased use of non-...
Researchers discovered that antibiotics can induce the production of pro-inflammatory compounds in the gut microbiome, which stimulates the immune system and induces antimicrobial peptides. This finding could lead to new therapeutic properties for these compounds in restructing the gut microbiome.
Researchers have developed a novel computational form-finding method that allows for the creation of complex, lattice-structured gridshells. This breakthrough method reduces computation cost by 98% and provides a standardized approach to designing attractive and robust gridshell structures.
Researchers visualize how silicon anodes form shell-like voids around their surfaces during charging, but find that parts of the solid electrolyte remain attached to the Si, maintaining partial ionic contact. This allows the battery to continue operating efficiently despite significant structural changes.
Researchers have developed a microneedle-based sensor to measure hypoxanthine levels, a reliable indicator of fish freshness. The sensor can detect concentrations as low as 500 parts per billion, making it a potential tool for real-time food-quality monitoring.
A new iron transporter protein, OsIET1, has been identified in rice, crucial for delivering iron to young leaves. The study reveals OsIET1 mediates inter-vascular Fe transfer, promoting optimal plant growth and productivity.
Researchers at Virginia Tech's Fralin Biomedical Research Institute are developing tools to gather high-quality brain function data during infancy, enabling studies on brain development and potential risk factors for disorders. The study aims to capture real-time brain activity during natural social interactions.
A recent study found thousands of missing transcripts in people from non-European populations, potentially leading to new insights into disease risk and genetic variations. The study highlights a lack of global representation in current gene maps, built largely from European DNA sequences.
A new study uses ultrasound to detect vascular complications from cosmetic fillers, such as absent blood flow to perforator vessels. Clinicians can now target exact areas for treatment, reducing the need for blind injections and minimizing complications like blindness and stroke.
Researchers have developed a new approach to overcome limitations in single-atom catalysts by creating one-dimensional organic polymers capable of selectively binding metal atoms. The platform marks a major advance in single atom catalysis, enabling stronger gas binding compared to other structures.
A Washington State University-led study suggests that college students who binge drink have more permissive parents and join fraternities or sororities. Parents with less restrictive attitudes toward drinking are also more likely to have children who engage in heavy episodic drinking.
Researchers at USC have identified four distinct layers of specialized cell types in the CA1 region of the mouse hippocampus, a structure vital for memory formation. This discovery changes our understanding of how information is processed in the brain and could explain why certain cells are more vulnerable in diseases like Alzheimer's ...
The SPHERE instrument has produced an unprecedented gallery of debris disks in exoplanetary systems, allowing for deductions of smaller bodies. These observations provide a glimpse of the earliest history of the solar system, with small bodies serving as remnants from planetesimals that did not evolve into larger planets.
A new study reveals that for every 10% increase in forest cover, an additional species is present, and sites with complete forest cover support three times the terrestrial vertebrate species compared to those lacking tree cover.
In-flight cardiac arrest is a rare yet catastrophic event that claims up to 86% of air fatalities. Implementing automated external defibrillators (AEDs) on board could significantly boost survival rates from 6% to up to 70%. The authors recommend standardized CPR protocols training, telemedicine integration, and mandatory AED placement.
Strong EAWM enhances upward heat fluxes, cooling sea surface temperatures south of Japan, modifying storm-track activity and intensifying the monsoon. A feedback loop emerges: cold air cools the ocean, reinforcing the monsoon.
A recent study found that releasing rehabilitated Golden Eagles can be an effective means of compensating for eagle deaths due to human actions. However, the study revealed that only a few rehabilitated eagles survive and integrate into the wild population, raising questions about the long-term efficacy of rehabilitation efforts.
Researchers at Tohoku University have demonstrated a water-resistant and recyclable redox-active metal-organic framework (RAMOF) that can store electrons in acidic aqueous solutions. The breakthrough material shows high durability in an aqueous RAMOF-based rechargeable battery.
Scientists found a cluster of non-visual, light-sensitive neurons in sea urchin larvae, similar to the vertebrate brain, and discovered that disrupting these neurons impairs light-dependent swimming behavior.
Researchers developed a three-dimensional carboxyl-carbon-nanotube-wrapped polyaniline catalyst that enables direct I⁰/I⁻ redox and delivers 420 mAh g–1 with ultra-long lifespan over 40,000 cycles.
A comprehensive review of over 2,500 articles found limited support for medical cannabis in treating chronic pain, anxiety, and insomnia. However, pharmaceutical-grade cannabinoids have demonstrated effectiveness in specific conditions like HIV/AIDS-related appetite loss and severe pediatric seizure disorders.
A University of California - Riverside study found that purchasing goods or services to be shared generates significantly more anxiety. Learning about others' preferences can reduce stress and increase confidence, but not if there are differing expectations.
Researchers have proposed a novel route to create high-performance electromagnetic wave absorbing materials by decorating 3D macroporous carbon foams with WC1-x nanoparticles derived from salting-out protein assemblies. This innovative approach offers a low-cost, green, and scalable pathway to advanced EWAMs.
Researchers introduce HierSpectrumChain, a hierarchical blockchain architecture for efficient and secure dynamic spectrum sharing among diverse wireless users. The system automates spectrum leasing through smart-contract–driven Stackelberg auctions, minimizing latency while maintaining transparency and trust.
Researchers at KAIST have developed a technology to directly observe nano-sized water droplets using an Atomic Force Microscope, enabling precise analysis of wettability. This breakthrough is expected to improve hydrogen production, fuel cells, batteries, and semiconductor processes.
Large language models are revolutionizing cardiovascular imaging by automating the interpretation of quantitative perfusion data in nuclear medicine and cardiac magnetic resonance. They also enable personalized protocol optimization in coronary computed tomography angiography, leveraging federated learning for data privacy.
A new study highlights the importance of protecting coastal ecosystems while building long-term environmental and cultural knowledge. The research, co-designed by Indigenous leadership and RMIT University scientists, found that a mangrove forest on the Barron River estuary stores over 2,000 tonnes of carbon annually.
Researchers developed micro/nano-reconfigurable robots that harvest sunlight to capture CO2, promoting carbon metabolism control in confined spaces. The robots demonstrated a 54.61% increase in survival time in a sealed-mouse model, offering an energy-frugal solution for space exploration and emergency shelters.
Robotic exoskeletons enhance cancer patients' mobility, muscle strength, and gait training while providing personalized support and real-time feedback. This innovation integrates traditional therapies, nutritional support, and cognitive behavioral therapy to improve therapeutic outcomes.
A new circular single-stranded DNA molecule has been developed to simultaneously silence multiple oncogenic miRNAs. The molecule, called circAMO, exhibits high biostability and can inhibit tumor cell proliferation, migration, and invasion in a concentration-dependent manner. It shows superior efficiency compared to existing anti-miRNA ...
Research shows that flooding in delta cities like Shanghai can expand by up to 80% and be much deeper by 2100 due to extreme climate events, sea-level rise and land subsidence. A major adaptation effort is required to raise defences and construct mobile flood barriers.
GenAI tools risk eroding medical students' critical thinking skills while reinforcing data bias and inequity. Medical educators must adjust curricula to mitigate these risks, warns an editorial in BMJ Evidence Based Medicine.
Creating a safe space free from body shaming is key to minimising female athletes' future risks of injury and protecting their health. The FAIR Consensus Statement provides practical recommendations for promoting gender-specific supportive environments in sports.
The FAIR Consensus Statement offers practical recommendations to reduce injury risk and improve safety in female, woman, and girl athletes. The guidelines mandate sport-specific strength exercises, enforced fair play, and proper equipment use to prevent injuries.
A Cochrane review found no significant effect of calcium supplementation on pre-eclampsia, contradicting long-held assumptions. The review excluded small and unreliable studies that previously suggested benefits of calcium supplementation.
SourceCochrane·JournalCochrane Database of Systematic Reviews·TypeSystematic review·DateDec 2, 2025
A major new study by UCL researchers reveals the challenges faced by London’s 1.3 million night workers, including pay inequality, health problems, transport difficulties, safety concerns, and a lack of workplace dignity. The study provides personal stories and policy recommendations to inform UK employment law reforms.
Researchers at Rice University have developed a way to make serum markers more sensitive by editing them inside the bloodstream, enabling clearer observation of gene-expression changes in the brain. This approach could lead to more precise diagnostic capabilities using simple blood tests.
Nearly one million children under five fail to reach their fifth birthday due to growth failure, a risk factor for mortality and morbidity. The study also found that stunting accounted for 12% of all child deaths, with 618,000 deaths in sub-Saharan Africa.
A new study finds Golden Eagles in Nevada at risk due to high mortality rates and habitat loss, potentially drawing in birds from other areas. Conservation efforts, such as maintaining natural habitat structure, are crucial to mitigating these impacts.
A global survey found that nearly 66% of shark descriptors were neutral, suggesting a shift away from the menacing predator narrative. Researchers used automated statistical packages and manual approaches to analyze short descriptions of sharks, revealing positive words like 'majestic' and 'fascinating'.
A recent study by UCLA Health found that a key genetic variant in the C3 gene increases the risk of chronic lung allograft dysfunction (CLAD) after lung transplantation. CLAD is the primary cause of mortality after lung transplantation, and the study suggests that impaired complement regulation drives this process.
Heriot-Watt University's IDRIC receives £2 million funding to advance UK industrial decarbonisation, building on five successful years of impact. The initiative will focus on research supporting regional and policy impact, identifying gaps in innovation.
A new study using a sediment core from Arizona's Stoneman Lake provides a unique record of dust emissions and pollen records in the region that spans multiple ice ages. The research reveals that the Southwest US produced significantly more dust during ice ages, contrary to other areas around the world.
A new study found that long-term antidepressant use has increased by nearly 20% among young people aged 10-24, raising concerns about potential overprescribing. The study also found no meaningful improvement in efforts to wean patients off antidepressants, highlighting the need for a stronger framework for safely tapering medications.
A new study by Mayo Clinic researchers found that using digital check-ins and a remote care team can help patients manage symptoms before they reach a crisis point. The trial showed that the automated surveys and responses built into the electronic health record made care more efficient and improved patients' symptoms.
A new neural network developed by Naveen Dhar can filter out false positives in gunshot detectors, providing accurate alerts for on-the-ground intervention. The system uses a web of autonomous recording units and a central hub to analyze audio data and pinpoint the location of gunshots.