Scientists report a scalable photonic neuron that processes complex data in real-time, achieving ultra-low latency. The architecture directly addresses scalability challenges and enables reconfigurable operation with temporal memory.
A lattice-like structure called the membrane-associated periodic skeleton (MPS) acts as a gatekeeper for endocytosis, regulating nutrient uptake and protein regulation in brain cells. Disrupting this structure can lead to accelerated endocytosis and increased cellular uptake of toxic molecules like amyloid precursor protein.
A recent Illinois study found that nearly 8,500 online classified ads for exotic amphibians were posted between 2004 and 2024, representing 301 species from around the world. The researchers verified a dataset of these listings, revealing 44 species traded without official paperwork, sold at a 40% premium. This illicit trade poses sign...
A new study published in Health Economics finds that universal free prescription drug coverage reduced average out-of-pocket medication spending by 23% and catastrophic drug expenses by 62%. However, the policy also led to unintended behavioral responses, such as increased spending on unhealthy goods.
A new study found that a key protein HOXD13 drives melanoma tumor cells' ability to grow with oxygen and nutrients. The researchers also discovered that HOXD13 suppresses the activity of cytotoxic T cells, which recognize cancer cells as abnormal and kill them.
Researchers at NTU Singapore develop a new orally taken, gut-based compound that reduces dietary fat absorption in the intestines. The technology supports weight loss while minimizing effects on other organs and reducing stress on the liver when dietary fat intake is high.
A recent study published in Neurology suggests that individuals with traumatic brain injuries (TBI) are more likely to qualify for work disability, regardless of the severity of their injury. The study found that people with TBI had a higher likelihood of having work disability during a five-year follow-up period.
Researchers developed an advanced organoid model for human spinal cord injury and tested a promising regenerative therapy. The treatment triggered neurite growth and reduced scarring in injured organoids, offering validation for its potential to work in humans.
A study of 2,700 adults found that South Asian adults in the US had higher rates of prediabetes, type 2 diabetes, and high blood pressure compared to peers from other populations. This suggests the need for earlier screening and risk-factor management to prevent heart disease.
A new testing method uses omics markers to reveal the trajectory of recovery from trauma, enabling more-tailored care. The approach shows that organ failure and mortality can be predicted with high accuracy using biological signals found in blood.
A new study suggests that nonablative capacitive-resistive monopolar radiofrequency (CRMRF) may improve vaginal health and sexual function in postmenopausal women. The treatment achieved significant improvements in overall sexual function, particularly in lubrication, orgasm, and pain.
A new study found that individuals with higher levels of lifelong learning developed Alzheimer's disease five years later than those with the lowest level of learning. Higher lifetime enrichment was also associated with a 38% lower risk of Alzheimer's disease and a 36% lower risk of mild cognitive impairment. The study suggests that pu...
A team of Chinese researchers has achieved device-independent quantum key distribution over 100 km, paving the way for practical long-distance quantum networks. This breakthrough enables the creation of scalable quantum repeaters, a critical building block for universal quantum computers.
A new USC Rossier study emphasizes the importance of early intervention in addressing housing instability among students. Key findings reveal that existing efforts focus on already homeless students, and that upstream interventions supporting at-risk families can prevent stability disruptions. The report highlights promising approaches...
Researchers at the UvA Institute of Physics have discovered how spherulites form in salt solutions, leading to the creation of advanced materials. The discovery reveals that subtle variations in composition and growth conditions can produce intricate internal architectures and high surface area structures.
Climate warming stimulates sphagnum growth, promotes iron protection, and inhibits microbial decomposition in boreal peatlands. This leads to increased soil carbon accumulation, potentially offsetting half of the decline in boreal forest carbon sink under future warming.
Dr. Bianca Seminotti has received the ACMG Foundation 2026 Early Career Travel Award for her abstract on mitochondrial function in congenital NAD deficiency due to biallelic NADSYN1 variants. The award supports promising young genetics professionals attending the ACMG Annual Clinical Genetics Meeting.
A new study by Mass General Brigham highlights the efficacy of proton therapy in achieving excellent tumor control rates while minimizing side effects compared to traditional radiotherapy. Proton therapy limits radiation exposure to healthy tissue, potentially preserving cognition and hormone function.
A new University of Michigan study finds large differences in financial outcomes, health and stability among formal and informal self-employed workers. Informal self-employment, including gig work, is concentrated among lower-income workers and faces significant challenges.
A nationwide Finnish registry-based study found no increased risk of pre- or postmenopausal breast cancer among women with a history of induced abortion or miscarriage. Breast cancer risks were similar regardless of the number of abortions or miscarriages, as well as the time of first abortion or miscarriage.
Research reveals fire-footed rope squirrels are a natural reservoir for the monkeypox virus, with evidence of interspecies transmission detected in Côte d'Ivoire. The study underscores the need for awareness among humans interacting with wildlife and deeper understanding of MPXV ecology to develop effective prevention measures.
LGB individuals vote more when living near other LGB people, with a 1.56 percentage point increase in voter turnout for every one percentage point increase in local LGB population density. This study, conducted in Sweden, tracked over 20,000 LGB individuals and nearly eight million heterosexual peers across four parliamentary elections.
The smokefree generation law, set to be introduced in 2027, could help stop young people from ever starting to smoke and accelerate progress towards a tobacco-free future. However, males and the most deprived communities may reach the 5% prevalence milestone later unless the law is effectively targeted.
A new study by The George Institute for Global Health found that 71% of grocery store baby food products in the US are classified as ultra-processed foods. These products tend to be cheap, convenient and hyper-palatable but lack essential nutrients.
Researchers developed a novel mouse model that accurately mirrors the progression and dynamic shift between disease states of lupus. The model demonstrates a direct link between skin defects and systemic disease, with dynamic features including remission and relapse cycles.
The American Society of Hematology released guidelines for frontline and relapsed/refractory management of acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYAs), outlining optimal approaches to treating high-risk patient populations. The guidelines highlight the need for additional research on immunotherapies and tr...
A new study by Flinders University researchers reveals a significant decline in southern right whale reproductive output over the past decade, driven by prolonged calving intervals. The study found that declining breeding rates coincide with reduced Antarctic sea ice, changes in oceanic conditions, and broader ecosystem shifts.
Researchers developed MAPPI, a system that enables real-time visualization of how a plant's leaves, stem, and roots communicate with each other in response to environmental stress. The system reveals bi-directional communication between leaves and roots, overcoming limitations of traditional microscopy.
Researchers used DNA barcoding to track cancer cells in solid and liquid biopsies, finding that tumour heterogeneity varies widely depending on necrosis and tumour burden. This study suggests that combining both strategies may provide a more accurate representation of the disease.
Researchers have uncovered a dense network of magnetic nodal lines in cobalt, which are intrinsically spin-polarised and give rise to fast, topologically robust charge carriers. These unique properties open new perspectives for exploiting magnetic topological states in future information technologies.
A new study finds that the quality of macronutrients matters more than their quantity for heart health, with diets rich in whole grains, fruits, and vegetables associated with a lower risk of coronary heart disease. The study also found improved cardiovascular biomarkers in healthy versions of low-carb and low-fat diets.
A case report investigates a woman's development of acute lymphoblastic leukemia and lymphoblastic lymphoma after receiving her second dose of the Pfizer-BioNTech COVID-19 mRNA vaccine, highlighting potential genetic and molecular mechanisms involved in disease pathogenesis.
Researchers at the University at Buffalo have developed a new inhalable form of tuberculosis (TB) treatment that delivers rifampin directly to the lungs, reducing liver damage and improving immune activity. The study found that inhaled nanoparticle treatment kept higher levels of the drug in the lungs for up to a week after a single dose.
Astronomers at UCLA and UCSD have discovered hydrogen sulfide in the atmospheres of four distant gas giant planets orbiting HR 8799, confirming their planetary status. The detection uses a new data analysis technique that will improve the search for life on other planets.
Researchers suggest that seabirds were used to fertilize Peru's Chincha Valley as early as 1250 CE, potentially supporting the growth of a pre-Inca society. This ancient practice could have played a significant role in the region's agricultural development.
A phase 3 trial will assess the efficacy of baricitinib in reducing persistent neurological and cardiopulmonary symptoms of long COVID. The study, REVERSE-LC, aims to address the massive public health problem of long COVID, which affects millions worldwide.
The center aims to strengthen food and environmental resilience, train the next generation of AI-enabled agricultural scientists, and help producers respond to emerging biological and climate threats. Students are immersed in federal agricultural research projects through a USDA-supported summer research program.
A new analysis found that rural cancer patients treated locally have similar surgical outcomes to those who traveled to urban facilities. The study used Surveillance, Epidemiology, and End Results data from Medicare-eligible patients with lung or colon cancer, aged 65 or older, residing in rural areas.
A new IIASA-led study examines critiques of global climate mitigation scenarios' equity and justice, proposing practical ways to advance fairness in climate pathways. The research synthesizes growing evidence that current scenarios fall short, identifying a roadmap for integrating fairness into future climate futures.
Ken Herrmann will lead the journal for five years, focusing on global engagement and impact. He succeeds Johannes Czernin, who guided JNM through significant growth and expansion.
Scientists have uncovered practical strategies that can significantly reduce harmful air pollution from composting while improving the quality of organic fertilizers. Biochar emerged as the most effective single solution, consistently reducing ammonia and nitrous oxide emissions while enhancing nitrogen retention.
Researchers have created a new computational method to simulate Tip-Enhanced Raman spectroscopy (TERS) signals with high accuracy. This enables the study of atomic motion down to individual molecules or defects in metallic surfaces. The method provides a detailed understanding of the signatures of local atomic motion and its sensitivit...
A new study identifies 36 genetic regions associated with bicuspid aortic valve disease, suggesting a polygenic contribution. The findings support the notion that BAV is an inherited disease caused by a combination of common genetic variants.
Researchers discover that magnetism can expand into unexpectedly large topological textures spanning hundreds of nanometres in twisted double-bilayer chromium triiodide. This finding challenges the assumption that magnetic order follows the moiré unit cell and opens up new possibilities for designing topological magnetic states.
A new study finds that US South Asians have higher rates of prediabetes, diabetes, and hypertension than other population groups, despite healthier diets and exercise habits. The study identifies a critical window in the 40s when risk is already high, but disease is still preventable with early intervention.
A new study assesses indoor heat vulnerability for each single-family home in Austin, finding that 85% of homes would pose significant risk to an elderly person during a power outage. The city can now take a methodical approach to mitigating risk through cooling centers and home weatherization programs.
Scientists in China have developed a novel silicon-based nanothrombolytic therapy that achieves efficient thrombus clearance and in situ regulation of the coagulation microenvironment while minimizing systemic bleeding risk. The strategy combines enzymatic clot dissolution with intelligent microenvironment reprogramming.
Researchers at UC San Diego developed a new training method for AI systems to improve their performance in solving complex problems that require both text and image interpretation. The approach evaluates the quality of training data and grades models based on their logical reasoning, reducing the risk of incorrect interpretations.
Insilico Medicine and CMS announce multiple collaborations on AI-empowered drug discovery in central nervous system and autoimmune diseases. The partnerships aim to accelerate research, development, and translation of high-potential innovative therapies, leveraging complementary strengths across the entire value chain.
A study published in Progress in Neurobiology found that synthetic oxytocin carbetocin can prevent anxiety-related behaviors in laboratory rats exposed to social stress. The researchers observed that carbetocin had a preventive effect on anxiety without having direct anxiolytic effects.
Researchers at Oregon State University have developed a deep learning-based model for rapid bacterial contamination detection, eliminating misclassifications of food debris. The enhanced model can reliably detect bacteria in three hours and has the potential to prevent outbreaks and protect consumer health.
Researchers discovered an mRNA-based therapy that instructs skin cells to produce telomerase reverse transcriptase (TERT), reducing DNA damage and protecting against genomic DNA injury. This breakthrough could lead to new therapies preventing radiation burns and long-term scarring, improving quality of life for millions of cancer patie...
Research led by Dr. Simon Grelet at the University of South Alabama has been recognized as one of Science magazine's Top 10 Scientific Breakthroughs of 2025. The study identified a novel mechanism by which neurons transfer mitochondria to cancer cells, fueling cancer metastasis and opening new possibilities for therapeutic intervention.
An international working group has been appointed to advance the Global Workforce Development in Stem Cell Research and Regenerative Medicine Initiative, a collaboration between ISSCR and Canada's Stem Cell Network. The initiative aims to strengthen workforce development and ensure the field of regenerative medicine delivers meaningful...
Researchers used advanced imaging to uncover early molecular changes in bone associated with osteoarthritis. The study found that subchondral bone beneath damaged cartilage showed strong upregulation of specific collagen fragments, suggesting that disease-related bone changes begin earlier than previously recognized.
A new study found that patients with Long COVID have a larger choroid plexus, which tracks with Alzheimer's disease markers and greater dementia risk. The research also suggests that CP alterations may predict long-term cognitive issues in some individuals.
Syracuse University professor Gabriel Merrin has developed a software tool called CATAcode to help researchers handle demographic data more thoughtfully. The tool addresses the issue of respondents selecting multiple options for characteristics such as race, gender identity, or other traits. By providing systematic approaches for explo...
A team of researchers at the Institute of Industrial Science, The University of Tokyo, developed an ensemble technique to improve climate modeling by tracing water molecules' movement. They found a general increase in atmospheric water vapor associated with warming temperatures, linking it to large-scale climate phenomena.
Researchers at George Mason University are developing an AI-driven proof-of-concept for cyber-physical manufacturing to address national security concerns. The project aims to integrate data-driven learning with knowledge-driven modeling for proactive detection and adaptive mitigation of cyber threats.
Researchers found that an experimental compound SB-216 reduced the growth of pancreatic ductal adenocarcinoma cells by inhibiting oncogenic microtubules and mitochondrial function. This approach may reduce cancer cell adaptation and survival.