Researchers at University of California - Riverside discovered that the primary cilium, a microscopic structure inside nearly every cell, plays a critical role in brain development. The study found that proteins associated with the cilium are directly linked to human developmental disorders and that protein production occurs directly w...
Researchers combined machine learning and multi-objective optimization to enhance PEMFC cold-start efficiency. The cathode catalytic approach used a non-electrochemical combustion reaction, providing high-power heating during initial startup while inhibiting ice accumulation.
Researchers at Lund University mapped the genome of Drosophila enhydrobia, a carnivorous fruit fly that lives entirely underwater in African streams. The study shows clear genetic adaptations to its unusual lifestyle, highlighting the importance of natural history museums for understanding biodiversity and evolution.
A study of over 400 pregnant women found that vivid mental images are directly linked to their opinion of vaccines and whether they get vaccinated. Positive mental images were associated with increased vaccination rates, while negative images predicted higher hesitancy towards certain vaccines.
Researchers from OU's Gallogly College of Engineering are developing autonomous cargo carriers to optimize logistics along the I-40 corridor in rural and tribal regions. The project aims to improve safety, efficiency, and reduce crash risks through autonomous vehicle technology.
Researchers found that X-shaped sleepers break down impact loads into a dense, uniform network of force chains, reducing stress concentrations and enhancing interlocking between ballast particles. This spatially diffused load transfer mechanism improves trackbed stability and impact resistance.
Researchers found no statistically significant changes in joint structures or evidence of inflammation following the 18-day mission. Ultrasound monitoring revealed stable cartilage thickness and tendon integrity.
This review highlights the integration of machine learning with adsorption science and engineering, achieving high precision and interpretability in adsorption processes. The reviewed studies demonstrate that machine learning enables accurate prediction of adsorption performance, accelerates material discovery and process optimization,...
The Baker McKenzie Award has recognized Dr. Alexander Heger's dissertation on European Competition Law and Air Transport for its outstanding analysis of a complex field. The award also goes to Dr. Felix-Julius Konow for his research on regulating stablecoins, which explores regulatory mechanisms to address economic and financial risks.
Researchers found that amphibian metamorphosis entails a direct cost, including weight loss and reduced energy intake, which varies by sex. The study uses the palmate newt as a model to shed light on the evolutionary mechanisms governing the persistence or loss of metamorphosis, particularly in the context of climate change.
Glioblastoma is a highly aggressive brain tumor that has seen modest improvements in survival rates over the past decade. Researchers at UCLA's Jonsson Comprehensive Cancer Center are part of a national effort to develop more personalized approaches to care, combining advanced imaging and analysis of tumor tissue samples and blood test...
The PanAMP study assesses the impact of PanCystPro on clinicians' decision-making for patients with pancreatic cysts. The study aims to provide insights into surveillance and treatment strategies for those at higher risk for pancreatic cancer.
The DFG Executive Committee presents a comprehensive position paper outlining its vision for the National Network of Data Platforms (NFDI). The document emphasizes the need for data sharing and collaboration to advance scientific research.
Researchers have found that formoterol, a widely used asthma medication, may reverse fatty liver damage and improve metabolic function. The study's findings suggest that the drug could be repurposed to treat MASH (metabolic dysfunction-associated steatohepatitis), a leading cause of liver transplantation.
A study by UPF found that AI-generated images of depression reinforce stereotypes and stigmas, particularly in terms of marginalization and social exclusion. The research highlights the need for responsible mental health communication, emphasizing the importance of considering diverse experiences and promoting transparency around AI use.
Researchers engineered an anaerobic bacterium to target periodontitis, reducing key pathogens and promoting tissue repair. The treatment lowered oxidative stress and restored the oral microbiome, offering a potential therapeutic solution for inflammatory diseases.
Researchers investigated the mechanisms of familial SQTS caused by SLC4A3 gene mutations, finding altered ion channel function and increased intracellular pH. The study revealed that correcting these mutations can prolong the action potential duration and reduce arrhythmias in human heart cells.
A new study introduces a sequential model to treat TMJ disc displacement, prioritizing joint stability over teeth alignment. This approach aims to prevent relapse and promote healthy jaw growth in growing patients and adults alike.
A new review highlights the escalating global burden of MASLD, which can progress to liver cancer, emphasizing the need for early detection and multifaceted treatment. Non-invasive biomarkers are being developed to improve diagnostic precision, including multi-omic panels and molecular markers that outperform traditional tests.
Researchers at Tohoku University and Nitto Boseki Co., Ltd. discovered that increasing anion size in Poly(ionic liquid)s (PILs) significantly improves CO2 adsorption capacity. The material with the largest anion achieved an adsorption capacity seven times greater than the raw material.
Researchers studied cyanobacteria Synechocystis to understand how it adapts to fluctuating light conditions, revealing mutations that enhance resilience. These findings may provide new strategies for improving crop tolerance to changing light intensities.
Barua's project aims to advance predictive maintenance and diagnostics of naval subsystems using power signatures, without intrusive sensors. By extracting hidden load features from existing logs, they aim to improve current naval energy systems and develop new compressed sensing methods.
Researchers have developed nanoparticles that sequentially disable the cancer cell's drug-expulsion mechanism and then release anticancer drugs, combined with photothermal therapy. This approach overcomes multidrug resistance and achieves complete tumor elimination in a mouse model, with no detectable toxicity to normal tissues.
A new urine test, MPS2-AS, performed better than PSA-based testing and MRI for monitoring low-risk prostate cancers on active surveillance. The test correctly predicted high-grade cancer in 97% of cases and avoided unnecessary biopsies by up to 64%.
This qualitative study explores the use of edible cannabis among older adults as a management strategy for pain, sleep, and mental health concerns. The study highlights the importance of physician awareness and informed counseling for these patients.
The US experienced substantially higher death rates than other high-income countries between 1999 and 2022, despite having comparable access to medical technology. These excess deaths could be avoided by adopting successful health and social policies from other high-income countries.
The US had substantially higher death rates between 1999 and 2022 compared to other wealthy nations, with cardiovascular diseases being the leading cause of excess mortality. An estimated 12.7 million US deaths could have been averted during this period if US mortality rates mirrored those of its peers.
A cluster randomized trial found comparable improvements in 6-month outcomes between intervention and control groups, indicating no independent effect of the clinical decision support system. The study suggests that other factors may be responsible for the observed benefits.
The study found a clear hump-shaped elevational pattern with species richness peaking at approximately 600 m, supporting the mid-domain effect. Community structure was differentiated by body size and biomass, with lizards contributing most of the individuals but only 66% of total biomass.
Researchers found that genome duplications during major environmental upheavals helped plants survive mass extinctions and extreme conditions. The study suggests that polyploidy, or having multiple sets of chromosomes, can be beneficial for plants in stressful environments.
A nationwide cohort study found a bidirectional association between premenstrual disorders and psychiatric disorders, highlighting the need for sex- and menstrual cycle–informed care in psychiatry. The study's findings emphasize the importance of considering menstrual cycles when diagnosing and treating psychiatric conditions.
A large language model-based agentic workflow produced AI-generated hospital course summaries with minimal risk of harm identified, reducing physician burnout. The study supports the viability of AI summarization to mitigate documentation burden.
A study by University of Utah Health found that older adults use cannabis edibles for non-psychoactive effects, seeking better quality of life. Many participants were influenced by positive anecdotes from friends or family members, highlighting the importance of word of mouth in their decision-making process.
Researchers explore how next-gen AI and sensor-rich operating rooms can enable more precise, data-driven, personalized surgery. Advances in multimodal data integration, machine learning, and robotic systems could enhance situational awareness and intraoperative decision-making.
A study of Maiasaura peeblesorum fossilized teeth reveals that juvenile dinosaurs likely received nutritious food while adults consumed tougher plant parts, indicating bird-like parental care. This behavior may have originated in dinosaurs and predates the emergence of birds.
Researchers at Yokohama National University have developed a new fiber-optic sensing method that uses electrical-domain interference to detect strain and displacement. The approach exploits relative modal delays in polymer optical fibers, resulting in measurable dips in the electrical-frequency domain.
Researchers discovered a 'hydraulic jump' causing massive cloud waves on Venus, connected to the planet's superrotation and sulfuric acid vapor. This phenomenon may also impact future Mars missions, with potential implications for planetary exploration.
Researchers create shape-morphing filaments using rotational multimaterial 3D printing, enabling programmable artificial muscles that bend and twist on demand. The breakthrough could accelerate the development of complex technologies such as soft robotics, energy damping, and biomedical devices.
A Harvard study resolves a longstanding climate puzzle by proposing that the Sturtian glaciation could have lasted 56 million years due to oscillating 'snowball' and 'hothouse' conditions. The researchers suggest intense weathering of volcanoes triggered global glaciations, which warmed and retreated over repeated cycles.
A team of researchers proposes that Dante Alighieri's Inferno was a gedankenexperiment in impact physics, modelling a planetary impact 500 years before modern meteoritics. The study suggests that Satan's fall from grace was inspired by the physical effects of a high-velocity impactor hitting the Earth's surface.
A systematic review found that structured exercise programs can modestly improve quit success, while a single bout of exercise can rapidly reduce nicotine cravings. Exercise type and intensity may also play a role in reducing cravings.
Researchers identify TGF-β signaling pathway as key regulator of osteoblast quiescence, suggesting its inhibition can aid in reactivation of dormant osteoblasts. Combining TGF-β-blocking antibodies with anti-sclerostin treatment shows promising therapeutic potential for osteoporosis treatment.
Researchers summarize universal mechanisms of regulatory T cells in solid organ transplantation, enabling durable immune tolerance and reducing rejection. Gene-editing technologies create hypoimmunogenic Tregs for standardized, scalable availability.
Adjunctive intravenous tirofiban increased the likelihood of an excellent outcome at 90 days in patients with acute ischemic stroke who had inadequate response to tenecteplase. The study found improved outcomes in these patients, providing new insights into treatment options.
Researchers review organoid-related regulations and progress in IND approval, highlighting the prospects and limitations of organoid models. Organoids are poised to reshape drug research and development with their high clinical relevance, shorter experimental cycles, and lower costs.
A new Northwestern University study finds metformin primarily targets the gut, driving glucose utilization inside cells lining the intestine to prevent blood sugar levels from rising. The drug slows mitochondrial energy production in gut cells, allowing the intestine to metabolize extra sugar and regulate blood sugar levels.
A study by ISGlobal reveals that regions with greater socioeconomic inequalities are more affected by cold weather, while areas with higher levels of wealth face a greater risk from high temperatures. The research quantifies the impact of socioeconomic factors on temperature-related mortality across 32 European countries.
The ECE 2026 brings together researchers and clinicians to share the latest endocrine research and developments. Key sessions include Plenaries, Symposia, Awards, Meet the Experts, Debates, and Oral Communications.
A study published in JAMA found that intravenous tenecteplase prior to endovascular treatment did not improve clinical outcomes compared to EVT alone for patients with proximal middle cerebral artery occlusion. The results suggest that EVT may be the preferred treatment option for this patient population.
A study published in the Journal for the Scientific Study of Religion found that over 40% of Japanese respondents identified as nonreligious or atheist yet still participated in rituals and believed in gods and the afterlife. The researchers highlighted the need for flexible tools to capture diverse forms of religiosity, particularly i...
A study by Children's Hospital of Philadelphia researchers found that over one in four pediatric patients treated for malaria in the US had a delay in diagnosis, leading to more severe infection and longer hospital stays. The study emphasized the need for prompt diagnosis and prevention of imported cases to improve patient outcomes.
A team at the University of Arizona discovered exceptionally fast and powerful galactic winds from quasars a billion years after the Big Bang. These winds could have caused galaxies to lose gas supplies, effectively shutting down star formation. The study suggests that quasars with extreme outflows were more common in the early univers...
Prof Chandra Sekhar, a globally respected leader in the industry, has made lasting contributions through his technical expertise and research leadership. He is internationally recognised for his work in indoor environmental quality, ventilation, and energy-efficient building performance.
Prof Liu Bin, a world-renowned researcher in organic functional materials, has been elected a Fellow of the National Academy of Inventors. Her groundbreaking work on light-emitting organic semiconductors has led to applications in medical diagnostics and optical data encryption.
Prof Lam received the award for his sustained impact on generations of students and his contributions to research and practice in healthy and sustainable built environments. He has advanced education through theoretical and translational research, integrating humanities with science and technology.
A study of 308 participants found that those with higher baseline ePTFp concentrations experienced a significantly steeper decline in kidney function over time. This association remained significant even when serum phosphate concentrations were within normal range.
A new study found that captive-raised saltwater crocodiles do not return to their breeding centers after release into the wild. This discovery can help inform conservation efforts by revealing that larger, captive-bred crocodiles may be more suitable for reintroduction programs.
A recent study found that lycopene protects porcine intestinal epithelial cells from DON-induced damage by inhibiting PGAM5-mediated mitophagy-dependent ferroptosis. Lycopene increases tight junction proteins, reduces ROS levels, and stabilizes mitochondrial function, restoring barrier integrity.
A study found mitochondrial morphological abnormalities and downregulation of mitochondria-related genes in patients who developed myocarditis after mRNA vaccination. Treatment with antioxidants and pharmacological inhibitors suppressed the condition. Sex hormones may also play a role in preventing cardiac dysfunction.
Children who engaged in regular outdoor play had lower sedentary time and higher moderate-to-vigorous physical activity in adulthood, while those experiencing exercise restrictions during childhood had lower adult physical activity levels. These findings support personalized lifestyle interventions for patients with CHD.