A new study found that people with the sickle cell variant are infected by a distinct variety of malaria parasites, which may contribute to their lower disease rates. The parasite strain is present in asymptomatic infections, differing between those with and without the sickle cell variant.
Two Scripps-led studies demonstrate the effectiveness of underwater acoustic enrichment in spurring coral and fish recovery efforts. The studies, conducted in Hawaii's Kāne’ohe Bay, show that playing sounds from healthy reefs can increase the presence of coral larvae and fish larvae on artificial reef structures.
Researchers identified a combination treatment that reprograms myeloid cells and boosts T cells, shrinking tumors and preventing recurrence. The approach showed a 40% long-term survival rate in murine models and holds promise for other types of recalcitrant cancer.
Researchers found that aripiprazole was associated with a lower risk of hyponatremia compared to olanzapine in a study combining US and Japanese data. The study suggests that the risk of hyponatremia may differ among individual second-generation antipsychotics.
Researchers found that minimal plating, with sauces placed separately, resulted in a higher perceived healthiness rating (4.65/7) compared to drizzle presentation (4.05/7). This suggests that visual simplicity and control over sauce usage may influence diners' initial impressions of a dish.
A twin study found strong links between screen time and mental health problems in adolescence, particularly for interactive activities like gaming and chatting. However, when shared family factors were accounted for, these associations weakened, suggesting that genes and upbringing play a significant role.
Researchers developed a nickel catalyst that controls an addition reaction with high precision, producing the anti form of β-amino alcohols with up to 96:4 selectivity and 99% enantiomeric excess. This breakthrough could provide a useful route for synthesizing anti-β-amino alcohols.
A new study estimates that cutting approval timelines for offshore wind farms by just one year can lower energy costs by around €1 per megawatt-hour. This could result in cost savings of roughly €110 million over the plant's 25-year operational lifespan.
Researchers have developed an affordable, open-source air quality monitoring device for wildlife, tracking particulate matter and providing insights into smoke exposure and behavior. The device can be attached to animal collars, filling gaps in data and delivering health insights for people exposed to smoke.
Researchers from Nagoya University developed a durable fuel-cell catalyst by wrapping platinum nanoparticles in nitrogen-containing graphene, retaining 96.9% of its active surface after 30,000 durability cycles. The new catalyst, Pt@N-FLG/SWCNT, has been reported to surpass the US Department of Energy's 2025 targets for electrocatalysts.
A new 'smart battery architecture' can extend electric vehicle battery life by over 20 percent by bypassing weak cells and making better use of remaining capacity. This can reduce total cost and increase sustainability, making it a great advantage for private car owners and fleets.
Researchers have identified a link between anorexia and rare genetic variants of a fat-storage gene, suggesting that altered fat metabolism may contribute to the disease. The study found that patients with anorexia were nearly four times as likely to carry potentially damaging variants of the PLIN4 gene, which regulates fat storage.
A recent study published in Cancer Discovery found that universal germline genetic testing detected a substantial proportion of inherited gene variants in patients with solid tumors, including high-penetrance and moderate-penetrance variants. These variants can carry potential implications for cancer treatment strategies. The study sug...
An international team identified ST6GAL1 as a key driver of glycocalyx remodeling, which shifts macrophages from an immunosuppressive state to a tumor-fighting state. Suppression of ST6GAL1 inhibited tumor growth in laboratory co-cultures, suggesting a potential strategy for cancer immunotherapy.
A study in mice shows that vaccination prevents long-term immune-related consequences after acute viral infection, preserving immune function. Vaccination was found to prevent the detrimental consequences of an acute viral infection, such as impaired immune responsiveness and splenic alterations, by preserving immune function.
A study of 1,400 employees in the UK financial sector found that women in male-dominated workplaces are less comfortable admitting mistakes and see them as less learning opportunities. In contrast, women in low-male-share environments have more positive views of mistakes.
A new study suggests that both autistic and non-autistic suspects may be judged more harshly in forensic interviews if their behavior deviates from societal norms. The research, published in Law and Human Behavior, challenges the widely held 'double empathy hypothesis' that autistic people can better read intentions and motivations in ...
A new mobile app, The Jetlag Fix, provides personalized plans for travelers to overcome jetlag, taking into account individual sleep timing, route, and dates. The app's science-backed computational model rates trip challenges and provides bespoke advice to reduce jetlag impact.
A new study by Flinders University highlights the risks of poor mental health and wellbeing in young athletes (17-24 years old) due to heavy dual-career demands. Young athletes who pursue sport for personal enjoyment and a love for the game tend to be more persistent and psychologically healthier.
Researchers at China Agricultural University developed a new method to assemble cooling films using acoustic vibration, reducing production time to one second. The process creates ultra-dense and pliable sheets that conduct heat efficiently, enabling faster and more reliable production of foldable electronics and wearable health patches.
The RED-ONION infrastructure enables fast and secure transfer of large research data volumes between the University of Osaka's D3 Center and SANKEN, facilitating AI processing and simulation analysis. This accelerates AI for Science research involving sensitive data, improving productivity in academic research.
A new conceptual framework treats spectroscopy as a computable language of matter, encoding identity, environment, and relationships governed by quantum mechanics. This framework could connect spectroscopy, machine learning, inverse design, and automated experimentation, enabling a more unified language for materials discovery.
Endosymbionts in insects drive cryptic speciation through ecological adaptation, gene transfer, and reproductive manipulation, leading to genetic differentiation and reproductive isolation
The article presents a new perspective on nuclear science, connecting fundamental physics with AI, major facilities, energy, medicine, and long-term governance. Key findings include the integration of theory, instrumentation, computation, and infrastructure as co-designed parts of the scientific process.
Researchers have developed an in situ cross-linked polyurethane gel electrolyte that tackles conflicting requirements for high-voltage Ni-rich cathodes and stable lithium deposition at anodes. The electrolyte achieves high electrochemical stability and ionic conductivity, enabling the stable operation of lithium-metal batteries for ove...
A team assembled the first gap-free telomere-to-telomere genome of Canavalia gladiata, combining with integrated transcriptomic and metabolomic profiling of developing seeds. The study reveals a metabolic switch during seed development, with a clear transition from starch and sucrose metabolism to fatty acid accumulation.
A Curtin University study found almost half of people who experience a concussion still experience problems a year later. Mental health and sleep disorders were identified as key risk factors for long-term symptoms. Despite this, 97% of participants returned to work within a year of their injury.
The study reveals that both sea lions and fur seals are most sensitive to sounds around 3.2 kilohertz, providing a baseline for assessing the impact of human-made noise on these marine mammals. The research findings could help inform environmental impact assessments and noise management as shipping and coastal development expand.
A newly discovered fossil, Megacauda sungei, uncovered key anatomical structures required for mammalian suckling and swallowing behaviors, evolving nearly 165 million years ago. The research challenges a longstanding assumption about the evolution of these structures, suggesting a more complex and nuanced origin story.
Seismic data captures ancient traces of mantle flow beneath the Pacific Ocean's oldest preserved piece of crust, tracking changes in tectonic plate motion and mantle deformation. The study reveals complex patterns of mantle flow in the region, with orientations aligned to both ancient and recent plate motions.
Researchers at the University of Auckland and the US National Institute of Science and Technology have successfully miniaturized optical frequency combs, enabling portable atomic clocks and precision sensors. The breakthrough could lead to applications in navigation systems, telecommunications, and sensors capable of detecting small ch...
A major new report from the European Society of Cardiology outlines how health services can protect people with heart disease in heatwaves. The report provides practical guidance on preparing patients for extreme heat, managing medication, advising on hydration and cooling, and monitoring patients during hot weather.
Researchers created a method for single-objective light sheet microscopy in commercially available sample chambers, reducing background light and photodamage. The new approach enables better imaging with less damage to samples, making it accessible to anyone with a compatible system.
Human stem cells from Adelaide University's Centre for Cancer Biology successfully travelled to the edge of space and back, providing new insights into cancer progression and early detection. The cells were exposed to microgravity for at least seven minutes, offering a unique opportunity to study their response.
Private equity investments rapidly reshape CPA firms, altering careers, culture, and skills needed. Experts urge higher education to bridge the gap between classroom instruction and workplace realities to prevent reality shock for new graduates.
A study of 9,000 injury patients in Africa and South Asia found that access to care, hospital route, and service type significantly impact survival and recovery. Patients arriving by ambulance had significantly worse outcomes, challenging the assumption that faster treatment leads to better outcomes.
A 19-year-old UK patient has become the first to undergo testicular tissue transplantation to help restore fertility after chemotherapy. The procedure, carried out by NHS Lothian and the University of Edinburgh, uses frozen testicular tissue to produce sperm.
A new Series led by Professor Asma Khalil found maternal RSV vaccination reduced hospitalisations by 74%, but unequal access limits benefits, with women in deprived areas having 72% lower odds of receiving vaccination. Experts call for coordinated action to prepare Europe for the next generation of maternal vaccines.
The study found that HPV vaccination before pregnancy is associated with a lower risk of major pregnancy complications, including preterm birth. Women vaccinated at an earlier age showed a greater reduction in risk. The study's results suggest that HPV vaccination may confer additional benefits beyond cancer prevention.
Children living with sickle cell anaemia in low-income settings can be treated safely with hydroxyurea, according to a new study. The study found no increase in clinically diagnosed infections, including malaria, among children receiving hydroxyurea treatment.
Three NHS genetics labs are failing to share vital genetic variant data with public databases, causing uncertainty and delaying treatment for rare disease patients. Experts and families say this failure is a
A global study found that vaccination against RSV during pregnancy lowers the risk of severe disease in babies by 74%, but uptake remains low in many countries. The study also reveals disparities in vaccine uptake among socioeconomic and ethnic groups, mothers of younger age, and those with reduced access to healthcare.
Researchers create new framework for classifying non-equilibrium quantum phases of matter, generalizing principles for closed systems to open systems. This breakthrough enables scientists to distinguish between a wider range of quantum phenomena.
The FDA has approved daraxonrasib, a targeted therapy, based on a global clinical trial. Patients who took daraxonrasib lived almost twice as long as those receiving chemotherapy. Meanwhile, a grant from the Pancreatic Cancer Action Network aims to establish a blood test for pancreatic cancer using circulating tumor DNA.
Researchers at the University of Pittsburgh and international collaborators have developed an optogenetics-based treatment that improved visual function in some patients with advanced retinitis pigmentosa. The treatment, which combines gene therapy and visual stimulation, showed encouraging results in tests of safety and efficacy.
Illinois physicists have created a model demonstrating that predictability can arise in nonchaotic systems, where even small changes in the initial state can lead to vastly different outcomes. The model's dynamics creates topological structures that can be used to predict the final fate of the system.
A peer-reviewed study found that a simulation game based on game theory helps students understand complex health economics concepts and insurance market dynamics. The game approach improved student engagement and learning in health economics courses.
A scoping review by George Mason University examines how advances in simulation and artificial intelligence are changing case-based learning in healthcare education. The review highlights the use of realistic simulations, lifelike mannequins, and chatbots to test students' judgment in high-pressure scenarios. The study's findings sugge...
A new study by Penn Nursing found that for-profit hospitals have higher mortality and readmission rates and less safe staffing conditions. Nurse staffing levels also play a significant role in these outcomes, with for-profit hospitals reporting lower safe staffing levels and higher nurse burnout rates.
Researchers at Monroe Carell Jr. Children's Hospital at Vanderbilt have successfully adapted a novel heart recovery technique, REUP, for pediatric patients, enabling the transplantation of 10 donor hearts in children and potentially expanding access to lifesaving heart transplants.
A new study demonstrates the safety and efficacy of optogenetic therapy for advanced retinitis pigmentosa, with 6 of 8 patients showing clinically meaningful improvements in visual tasks. The treatment, which combines gene therapy and light-stimulating goggles, enables blind individuals to detect objects and navigate their environment.
Researchers reconstruct a lush landscape of woodlands, wetlands, and waterways from the Pleistocene, inhabited by giant elephants and early toolmakers. The findings provide a rare glimpse into the environment shared by early humans and giant elephants, shedding light on human origins and the forces that shaped our species.
A landmark survey has revealed the Seychelles' giant tortoise population to be thriving and stable at approximately 180,000 individuals, following years of conservation efforts. The population is now considered healthy and stable, with the highest figure ever recorded for the species.
Researchers at Memorial Sloan Kettering Cancer Center identify a critical inflammatory signaling pathway and its role in protecting healthy cells from immune response damage. The discovery opens new avenues for understanding diseases where inflammation runs amok, including cancer, inflammatory bowel disease, and asthma.
Elevated lipoprotein(a) levels are associated with the progression of carotid atherosclerosis in East Asian populations. Participants with high Lp(a) levels (>50 mg/dL) had a higher risk of developing carotid plaques and faster progression to carotid stenosis, highlighting the importance of measuring Lp(a) for risk stratification.
Tampere University Hospital is introducing a novel radiotherapy to treat rectal cancer, targeting the tumour surface with high doses of radiation. This treatment aims to destroy the tumour, potentially avoiding major surgery and a stoma, and is being investigated in the NORPPA-2 study.
The event offers maternity unit tours, opportunities to meet care teams, and resources to help families prepare for a new baby. Local vendors will also be present.
A new Horizon Europe project, FIMI-RESIST, aims to evaluate the effectiveness of existing European tools against disinformation. The project, led by Johannes Gutenberg University Mainz, will assess 20 EU-funded tools using common criteria and shared benchmarks.
A new study from the University of Colorado Anschutz reveals how Prevotella melaninogenica reprograms immune cells to more effectively clear pneumonia-causing bacteria. The findings suggest that the lung microbiome may be part of the body's first line of defense against respiratory infections.
A national study found that individuals with higher neuroticism scores experienced greater and more persistent anxiety and depression symptoms during the pandemic. The study suggests that personality traits, particularly neuroticism, play a role in shaping mental health responses to large-scale societal stressors.