In a groundbreaking study, African-American men with high blood pressure showed significant improvements when aided by pharmacists and local barbers. Nearly two-thirds of participants achieved healthy blood pressure levels after six months, with systolic blood pressure dropping from 153 mmHg to 126 mmHg.
A new study shows that injecting cardiac progenitor cells can reverse fatal heart disease caused by Duchenne muscular dystrophy, while also improving limb strength and movement ability. Exosomes secreted by the injected cells unexpectedly restore muscle function in a mouse model of muscular dystrophy.
A new study published in Circulation found that 8% of women with chest pain have myocardial scar, indicating previous heart muscle damage. The study suggests that women be taken seriously when complaining of chest pain and receive appropriate medical care.
A recent study found that nearly 60% of cases studied had combinations of obesity, hypertension, high cholesterol, diabetes, and smoking. Researchers suggest extending prevention efforts to routine preventive visits for children and young adults to reduce adult cardiovascular disease.
Researchers discovered that limiting an amino acid called asparagine can dramatically reduce breast cancer's ability to travel, suggesting a potential strategy to prevent its spread. Foods high in asparagine include dairy and meat products, while fruits and vegetables are low in this compound.
A specialized stenting system has been shown to benefit certain stroke patients by reducing the risk of complications. The Wingspan Stent System Post-Market Surveillance Study found a complication rate of just 2.6 percent among patients with intracranial stenosis due to cholesterol plaque.
A new study provides guidelines for assessing the severity of head and neck cancers by counting malignant lymph nodes, which are found to be a key factor in predicting patient survival. The number of positive nodes can categorize patients into distinct groups with varying outcomes.
A study by Cedars-Sinai researchers found no statistically significant impact of wearable biosensors on clinical outcomes such as weight, blood pressure, and body mass index. Despite early promise for certain conditions like obstructive pulmonary disease and Parkinson's disease, the devices' effectiveness remains unproven.
Cedars-Sinai finds that pharmacy staff taking medication histories reduces errors in both patient records and medication orders by over 80%. Pharmacy staff are now assigned to take medication histories for high-risk patients admitted through the Emergency Department.
A Phase I/II clinical trial found that cardiac progenitor cell infusions improved heart function and arm strength in patients with Duchenne muscular dystrophy. The study showed a 7% reduction in heart scar tissue and improved skeletal muscle function in the hands and forearms of patients who received the treatment.
A new study from Cedars-Sinai Medical Center found that the risk of sudden cardiac arrest during or after sex is exceedingly small. The study analyzed over 4,500 cases and found that only 34 cases occurred during or within an hour of engaging in sex, with nearly 20% of these patients surviving.
A new study by Cedars-Sinai investigators reveals how staph bacteria trick the body's immune system, allowing repeated infections throughout life. The study sheds light on how to develop an effective vaccine harnessing T cells to combat the superbug MRSA.
Researchers developed a noninvasive eye scan to detect Alzheimer's disease years before symptoms appear, revealing amyloid-beta deposits and toxic proteins in the retina. The findings offer new hope for early detection and disease monitoring, with the potential to intervene and change the course of the disorder.
A new study by Cedars-Sinai Medical Center suggests that cardiac stem cell infusions could reverse aging in the human heart. Cardiosphere-derived cells secrete tiny vesicles containing RNA and proteins, which may turn back the clock for age-related heart conditions.
A study led by Cedars-Sinai found that patients with lower Braden Scale scores have higher risks of nonambulation, prolonged hospital stays, and rehabilitation facility discharge after liver transplantation. Supervised exercise programs may improve physical functioning and quality of life for these patients.
Researchers found that treating patients with IdeS drug before transplantation significantly reduced donor-specific antibodies, allowing successful kidney transplants. The enzyme, produced by Streptococcus pyogenes, can remove organ-rejecting antibodies, making kidney transplantation possible.
A recent study published in the Journal of the American Heart Association found that health insurance expansion through the Affordable Care Act significantly reduced the incidence of sudden cardiac arrest among middle-aged adults who were previously uninsured. The study analyzed emergency medical services data from an urban Oregon coun...
A new risk assessment tool has been developed by Cedars-Sinai researchers to predict and prevent sudden cardiac arrest. The score is calculated using widely available and inexpensive 12-lead electrocardiogram (EKG) technology, and patients with scores above 4 have a 20 times increased risk of sudden cardiac arrest.
A new study reveals that nearly half of US women are not aware of the leading cause of death among females, with only 40% reporting a heart health assessment by their healthcare provider. Women's Heart Alliance reports alarming data on delayed medical care due to weight concerns and lack of education.
A major new study published in The New England Journal of Medicine found that completion lymph node dissection, a procedure to remove all lymph nodes near the original tumor, does not increase overall survival rates for melanoma patients. However, it can help gauge cancer spread and disease-free time.
A study by Cedars-Sinai Medical Center found that one in three hospitalized patients experience symptoms of depression. Depressive symptoms can delay recoveries, increase hospital stays, and lead to readmissions. The study emphasizes the importance of initiating a depression screening program in hospitals.
A Cedars-Sinai study found that quality improvement programs can significantly reduce hospital readmissions for heart failure patients and older adults with diverse health issues. However, the study's findings also showed that these interventions may not always result in net savings for healthcare systems.
Researchers analyzed thousands of social media posts to find that IBD patients are more concerned with the risks of biologic medications than their benefits or financial costs. The study suggests that physicians need to do a better job explaining the pros and cons of treatments.
A Cedars-Sinai-led team developed a technique that cues bone to regrow its own tissue, potentially replacing bone grafts. The innovative method combines ultrasound, stem cell and gene therapies to mend severely broken bones.
Researchers developed a lab-based model of the blood-brain barrier defect that causes Allan-Herndon-Dudley Syndrome, a rare congenital disorder. The study may hold promise for treating this syndrome and analyzing other neurological conditions.
Researchers used 3-D prints to compare three surgical techniques for treating Charcot-Marie-Tooth disease and found that none provide adequate correction of the heel bone deformity. The study, funded by the Charcot-Marie-Tooth Association, was presented at the American Academy of Orthopaedic Surgeons annual meeting.
Researchers identify that cardiac muscle cells both destroy and create new mitochondria in response to ischemia/reperfusion injury, which can cause long-term effects or fatal heart failure. This discovery may lead to the development of new treatments to speed up healing from open-heart surgery.
A new study published in JMIR Mental Health found that virtual reality therapy significantly reduced pain scores in hospitalized patients. Patients who wore VR goggles experienced a 24% drop in pain, while those who viewed standard video content saw a 13.2% decrease.
Researchers found that patients without the ZEB1 gene tend to have lower survival rates, as this gene regulates tumor growth. The study's results could lead to more accurate prognoses and personalized treatments for brain cancer patients.
A Cedars-Sinai study suggests that hormone replacement therapy is linked with lower levels of plaque buildup in the heart's arteries and improved survival rates among women. Women using HRT were found to be 30% less likely to die than those not on the therapy.
The Cedars-Sinai Heart Institute is developing a biological pacemaker that can treat patients with slow heartbeats. The device turns normal heart cells into pacemaker cells using gene therapy, potentially replacing electronic pacemakers one day.
Cedars-Sinai neuroscientists have uncovered the human brain's processes involved in creating and maintaining short-term memories. The study found that persistently active neurons in the medial frontal lobe and medial temporal lobe are critical for memorization, with activity levels correlating to memory recall.
A new treatment regimen combining hormonal therapy with radiation treatment significantly improves the average long-term survival of men with recurrent prostate cancer who have had their prostate gland removed. The study found that this regimen also reduces the frequency of spread of the cancer, improving patient outcomes.
A recent study by Cedars-Sinai found that implementing rigorous catheter safeguards can significantly reduce bloodstream infections related to central venous catheters. The study, which analyzed data from 113 hospitals, showed a 57% reduction in infection rates while producing net savings of $1.85 million for each site over three years.
A recent study has identified more than 2,000 genetic mutations in tissue samples of esophageal tumors, revealing the complexity of cancer cells within individual tumors. The findings demonstrate that different areas of a tumor have unique genetic patterns, making it difficult to target a specific genetic defect.
Researchers found a link between the loss of hyaluronan and AEC2 stem cell failure, leading to scarring in lungs. The study highlights potential treatment pathways using drugs that stimulate AEC2 cell reproduction.
A research team at Cedars-Sinai will use a $1.2 million grant to design a system using remote monitoring to predict heart attacks and other cardiovascular events. By combining different types of data, they aim to identify early signs of cardiovascular disease and empower patients to better manage their conditions.
Researchers at Cedars-Sinai discovered that cutting nerves to the kidneys dramatically improves liver sensitivity to insulin, effectively curing insulin resistance in laboratory animals. The study reveals a previously unknown communication pathway between the kidneys and liver to regulate blood sugar levels.
The Cedars-Sinai Board of Governors Regenerative Medicine Institute is conducting the first human trial of a novel combined stem cell and gene therapy for ALS patients. The therapy aims to preserve leg mobility by providing supportive cells that produce glial cell line derived neurotrophic factor (GDNF).
Cedars-Sinai has awarded nearly $700,000 to scientists developing new treatments and technologies for precision health. The goal is to tailor therapies and medications for specific patients based on their molecular makeups.
Cedars-Sinai Heart Institute researchers collaborate with DoD and VA to study cardiac progenitor cells for heart failure with preserved ejection fraction, a condition affecting millions. The clinical trial aims to improve symptoms and treatment options for patients.
Researchers developed a new way to identify aggressive prostate cancer patients by analyzing their tumor's genetic pathways. The study found three subtypes of prostate tumors, with one subtype showing high disease progression and poor clinical outcomes.
Researchers discovered a metabolic enzyme that acts as a gatekeeper for the innate immune system, triggering strong inflammatory responses against harmful bacteria. This finding may help explain why obesity, Type 2 diabetes, and coronary artery disease are often accompanied by inflammation.
Researchers at Cedars-Sinai Medical Center have discovered that current engineered stem cells are too immature to accurately model ALS. To improve this, they suggest 'aging' the motor neurons in a laboratory dish to better represent the disease's progression.
Julia Ljubimova, MD, PhD, receives grant to advance research on tumor nanoimmunology and develop new generation of drugs for brain, breast, lung cancers. The goal is to improve immune system and block tumors from forming.
Researchers at Cedars-Sinai Medical Center discovered that genetic variants can prevent 'good' gut bacteria from functioning properly, contributing to the development of Crohn's disease. This study provides new insight into the interaction between genes and microorganisms in promoting health and preventing inflammation.
Investigational stem cell therapy derived from a patient's own blood marrow significantly improved outcomes in patients with severe heart failure. The study found that the treatment reduced deaths by 37% and hospitalizations by 49% compared to placebo.
A study by Cedars-Sinai researchers found that the C9orf72 gene is crucial for immune cell function in the brain, leading to potential new therapies for ALS. The discovery highlights the active contribution of the brain's immune system to disease progression.
Researchers at Cedars-Sinai Medical Center have made a breakthrough in treating heart failure with preserved ejection fraction, a difficult-to-treat condition affecting millions. Cardiosphere-derived cells (CDCs) infused into laboratory rats reversed the condition, improving heart function and filling capacity.
Researchers at Cedars-Sinai are working on a new risk assessment tool to identify patients susceptible to sudden cardiac arrest. The goal is to predict those at risk for the fatal heart rhythm malfunction, which claims 350,000 lives annually in the US.