David Moutard, a Wayne State University graduate student, has been selected to participate in the Office of Science Graduate Student Research (SCGSR) program. He will conduct research at the Lawrence Berkeley National Lab and study transient astronomical events, including supernovae and tidal disruption events.
Researchers at Wayne State University aim to address impaired relaxation of heart muscles through novel biomechanical tests and imaging techniques. The project, funded by the National Heart, Lung, and Blood Institute, will investigate how mechanical properties of the heart relate to models of heart failure.
Researchers at Wayne State University found that zinc supplementation can prevent mitochondrial damage in young egg and sperm cells, as well as enhance immunity against COVID-19. Zinc may also improve embryo quality and potentially lessen some pregnancy complications.
A Wayne State University research team is developing an artificial intelligence (AI) model to help identify severe SARS-CoV-2 illness in children. The project aims to predict disease severity and risk stratify patients, enabling early detection and timely intervention.
A Wayne State University study will explore how family migration stress affects infant development and health. The research, led by Dr. Dalia Khalil, aims to identify effective early intervention strategies for immigrant families.
The National Institutes of Health has awarded Wayne State University a total of $5.59 million to support research into preventing and treating cerebral palsy. Dr. Sidhartha Tan's projects aim to develop new drugs targeting neuronal nitric oxide synthase and explore the role of tetrahydrobiopterin in brain injury.
The Michigan Translational Research and Commercialization program awarded Wayne State researchers $270,000 to develop transformative innovation projects in AI, AR, and intelligent automation. The funding will support projects led by Jeremy Rickli, Ming Dong, and Arash Javanbakht, aiming to bring disruptive solutions to the market.
A new DOE grant will support research on developing efficient electrochemical systems for renewable energy generation and storage. Dr. Eranda Nikolla's project aims to design catalytically active sites in non-stoichiometric, mixed metal oxides for oxygen reduction and evolution.
A Wayne State University team has made significant breakthroughs in understanding the causal relationships between nonalcoholic fatty liver disease (NAFLD), type-2 diabetes, and obesity. They discovered two subtypes of NAFLD: one caused by genetic factors and another driven by metabolic syndrome.
A new patient-focused intervention, DISCO App, has been developed to improve patient-provider treatment cost discussions and related patient outcomes. The five-year grant-funded study will evaluate the effectiveness of the app in reducing financial toxicity among cancer patients.
Researchers from Wayne State University are developing a COVID-19 risk-prediction system to assess infection risk at different levels, including individually and at large-event levels. The system, CORPUS, will use edge intelligence and machine learning to predict risk based on various data inputs.
A Wayne State University team, led by Miriam Greenberg, is working on potential new targets for treating Barth syndrome, a life-threatening X-linked genetic disorder affecting mainly males. The four-year grant aims to identify specific metabolites as candidates for new treatments.
A new study provides the first in-depth look at the human sperm microbiome using RNA sequencing. The researchers found that non-targeted sequencing of human sperm RNA can identify micro-organisms such as bacteria and viruses, offering a potential diagnostic tool for microbial status and fertility assessment.
A new photoacoustic tomography technique aims to improve the detection and measurement of hypoxic-ischemic brain injuries in preterm newborns without sedation or radiation. The technology has the potential to revolutionize neonatal brain imaging management, enabling earlier treatment and improved outcomes for patients.
The TRUE Project will prepare 36 diverse professionals as K-12 STEM teachers over 18 months, integrating culturally responsive education and trauma-informed learning. The project aims to fill openings in science and math classrooms with a diverse pool of teachers.
A Wayne State University research team will develop algorithms to detect and prevent cyberattacks on chemical process control systems, enhancing production efficiency and safety. The three-year project aims to create stronger safeguards against automation system attacks.
A team of researchers at Wayne State University is developing a novel oral insulin delivery system to address the issues of low absorption and bioavailability. The goal is to create a safe and efficient treatment that can enhance the quality of life for diabetes patients.
Researchers at Wayne State University and Henry Ford Health System aim to develop a new therapeutic approach to reduce opioid addiction relapse using dual orexin antagonism. The study will investigate the role of sleep disturbance in opioid use disorder and its potential link to treatment cessation.
African Americans have lower survival rates and shorter survival times after cancer diagnosis compared to other racial groups. A new NIH-funded study will investigate the impact of community, interpersonal, and individual factors on health-related quality of life for African American cancer survivors.
A team of Wayne State University researchers is working to better understand the physical, chemical, and biological character of fatbergs through advanced analysis. Their study aims to identify contaminants in fatbergs and inform targeted prevention and mitigation efforts.
The ReBUILDetroit program, a partnership between University of Detroit Mercy and Wayne State University, has received a $19.4 million NIH grant renewal to provide scholarships and stipends for students enrolled in the program. The program aims to encourage underrepresented students to pursue careers in biomedical research.
The Detroit Cardiovascular Training Program at Wayne State University has received a significant boost from the NIH, with $1.29 million in additional funding. The program, which began in 2014, will now offer training to six trainees instead of four, strengthening its ability to attract top talent.
Researchers used electrocorticographic data from surgically implanted electrodes to investigate memory development in a cohort of 17 children and adolescents. The study found that earlier activity predicts greater memory accuracy, and sub-second deviations in activity flow between frontal subregions predict memory formation.
The Wayne State University team will address hypertension, hyperlipidemia, and obesity through innovative approaches to comprehensive population health initiatives. They will explore the use of community health workers, telehealth smartphone applications, and bi-directional referrals to promote better management of these conditions.
A Wayne State University research team received a $1.57 million NSF grant to study the interaction between drinking water and public health systems during crisis events. The project aims to enhance resilience and promote access to cleaner drinking water for vulnerable populations.
Researchers at Wayne State University have developed a nanoplatform technology that works in combination with existing chemotherapeutic drugs to reverse drug-resistance in renal cell carcinoma. The technology uses tumor hypoxia-directed nanoparticles to target the root cause of the problem and has shown promising results in animal trials.
A new diagnostic blood test developed by Banyan Biomarkers Inc. has been validated to correctly identify 99.6% of patients without traumatic brain injury (TBI) on head CT scans. The test reduces unnecessary head CT scans, radiation exposure and healthcare costs associated with TBI treatment.
A $1.54 million NIH grant will support research on modifying troponin T to improve cardiac function in heart failure. The study aims to develop a new approach for treating this condition by targeting the physiological modification of cardiac troponin T.
Researchers at Wayne State University are investigating the link between glutamate and memory processes in aging populations. The study, led by Drs. Jeffrey Stanley and Naftali Raz, aims to identify subtle deviations in brain chemistry that may indicate impending cognitive decline.
Haipeng Liu, assistant professor of chemical engineering at Wayne State University, received a $539,422 NSF CAREER grant to develop molecular adjuvants that can enhance the effectiveness of cancer vaccines and overcome tumor-related immune suppression. His research aims to bridge the gap between synthetic chemistry and immunology.
The Wayne State University College of Nursing is expanding its BSN training program with a $2.6 million HRSA grant to address the growing need for nurses working on community-based primary care and public health teams. Students will participate in immersive clinical experiences alongside RNs in Detroit's community settings.
Pai-Yen Chen, a Wayne State University professor, has received a $500,000 NSF CAREER grant to develop more efficient wireless wearable sensors using graphene-based bioelectronics. The technology holds promise for monitoring ocular health and detecting diseases.
Kristin O'Donovan's NSF-funded project examines how local governments learn from disaster experiences and the limits of policy change, shedding light on vulnerability differences between communities.
Researchers at Wayne State University are investigating a potential new direction for treating Barth syndrome, a rare and life-threatening genetic disorder. The study aims to activate pyruvate dehydrogenase (PDH) and/or supplement deficient metabolites to reveal a new treatment approach.
A statistical analysis found that most Legionnaires' disease cases in Flint can be attributed to the city's switch to the Flint River water source. The study also identified a specific strain of Legionella isolated from Flint residences that is not easily detectable by common diagnostic tests.
A new NIH-funded study aims to examine the association between environmental exposure to lead and cadmium and hearing loss in Detroit firefighters. The research project will test the hearing of 200 firefighters and assess genetic factors and bone lead levels.
A study by Wayne State University School of Medicine researchers found that sperm RNA elements can predict human health, potentially leading to improved fertility clinic predictions and better neonatal care outcomes. The discovery may also enable the development of preventive measures against diseases.
A new meta-analysis confirms the effectiveness of vaginal progesterone in reducing preterm birth risk and improving perinatal outcomes for women with a shortened cervix. The study found significant reductions in preterm birth rates and neonatal complications, as well as improved childhood neurodevelopment.
A Wayne State University research team has received a $1.85 million NIH grant to investigate non-Shine-Dalgarno translation initiation in bacteria. The goal is to identify new antibiotic targets effective against pathogens lacking Shine-Dalgarno sites.
A Wayne State research team is developing a novel approach to treat bacterial endophthalmitis with Resolvin D1, which has shown promise in reducing inflammation and preventing tissue damage. The study aims to identify new anti-inflammatory therapeutics for the prevention and treatment of blinding ocular infections.
Three WSU research teams received $1.1 million in funding to develop innovative biomedical technologies, including a smart artificial urinary sphincter and zwitterionic hydrogel-based islet encapsulation technology. The award complements Wayne State's Technology Commercialization Office and MTRAC Program.
Wayne State University will analyze 20 years of fetal alcohol spectrum disorders data to refine the new diagnosis and provide support for official recognition in the DSM. The study aims to identify key developmental outcomes, prenatal alcohol exposure levels, and critical dose effects.
A novel therapy, Emotional Awareness and Expression Therapy (EAET), has been found helpful in reducing widespread pain and symptoms of fibromyalgia. Patients who received EAET showed significant improvements compared to those receiving education or cognitive behavioral therapy.
Researchers at Wayne State University aim to develop an Autonomous Battery Operating System (ABOS) to enhance energy efficiency, lifespan and security of battery systems. The project will investigate the effectiveness of ABOS in a realistic environment, testing its ability to control physical battery systems and predict battery state.
A research team led by Deborah Ellis aims to improve asthma management and reduce deaths among minority children, with a focus on African American adolescents. The project will test an adapted intervention, REACH for Control, in real-world settings.
The Wayne State University team will train 122 students in an interdisciplinary approach to address complex urban problems, integrating science, engineering, policy, economics, and communication.
Researchers at Wayne State University are developing new therapeutic treatments and targets for environmental remediation for cholera using a zebrafish animal model. The goal is to better understand the infectious cycle and genes involved in causing the disease.
Researchers at Wayne State University are exploring leukodystrophies and genetic Leukoencephalopathies, rare disorders affecting the central nervous system. They will use a zebrafish mutant line of Vacuolar Protein Sorting 11 to better understand the progression and model for a disease causing progressive vision loss.
A Wayne State University researcher has received a $1.9 million grant from the National Institutes of Health to study the role of AMP-activated protein kinase in regulating innate responses to bacterial endophthalmitis. The study aims to identify novel pathways and new means to treat blinding ocular infections.
A Wayne State University researcher is leading a clinical research study to develop a better understanding of type 2 diabetes in obesity and improve therapy for veterans and others with the disease. The study aims to characterize a cohort of obese people with and without Type 2 diabetes to distinguish different genetic subtypes.