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Patients with severe brachial plexus injuries who undergo amputation report benefits, Mayo study finds

A Mayo Clinic study found that patients with severe brachial plexus injuries who undergo amputation experience reduced mechanical shoulder pain and higher employment rates. The study also showed improved prosthetic use among patients with myoelectric prostheses, suggesting a potential benefit to amputation for some individuals.

SourceMayo Clinic·JournalJournal of Bone and Joint Surgery·DateJun 30, 2022

Armed Forces Personnel who are injured in combat at greater risk of poor mental health

New research from King's College London found that members of the British Armed Forces who were physically injured while fighting in Afghanistan are more likely to experience poor mental health, including depression and PTSD. The study also suggests that the type of injury sustained can influence the overall outcome.

SourceKing's College London·JournalThe Lancet Psychiatry·TypeObservational study·DateJun 16, 2022

Study shows amputation, hospitalization rates fell among minorities following Medicaid expansion

A new study reveals that Medicaid expansion under the Affordable Care Act has led to a significant decrease in diabetic foot amputations among racial and ethnic minority adults. The study found that this expansion has resulted in better healthcare outcomes for these underserved populations, reducing rates of diabetes-related major ampu...

SourceUniversity of Arizona Health Sciences·JournalJAMA Network Open·TypeData/statistical analysis·DateMay 5, 2022

Personalizing treatment for severe limb injuries

A team of scientists at the University of Missouri used small wearable sensors to gather data on how people with a traumatic hand amputation use a prosthesis versus a transplanted hand. The study found that hand transplant recipients exhibit a more balanced pattern of limb use, while prosthesis users rely heavily on their prosthetic hand.

SourceUniversity of Missouri-Columbia·JournalNeurorehabilitation and Neural Repair·DateJan 10, 2022

Power walk

Researchers developed a powered exoskeleton that provides extra energy for walking, reducing the strain on amputee muscles. The device was tested by six individuals with above-knee amputations, showing a 15.6% improvement in metabolic rate and allowing users to walk for extended periods.

SourceUniversity of Utah·JournalNature Medicine·DateOct 11, 2021

Cleveland Clinic researchers develop bionic arm that restores natural behaviors in patients with upper limb amputations

Researchers created a bionic arm that combines intuitive motor control with touch and hand movement sensation, enabling wearers to think and behave like a person without an amputation. The system's bi-directional feedback and control allowed study participants to perform tasks with similar accuracy as non-disabled people.

SourceCleveland Clinic·JournalScience Robotics·DateSep 1, 2021

Amputation rates higher for people with PAD who are poor or Black; other health gaps noted in special issue

A study published in the Journal of the American Heart Association found that people with peripheral artery disease (PAD) living in poor or Black metropolitan areas have higher amputation rates. The analysis also noted significant disparities in healthcare access and quality among different racial and socioeconomic groups.

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateAug 25, 2021

Synthetic hinge could hold key to revolutionary 'smart' insulin therapy

A synthetic hinge concept developed by Indiana University School of Medicine Professor Michael A. Weiss and his team could lead to a breakthrough in 'smart' insulin therapy. The invention exploits a natural mechanism that allows the insulin to adjust its activity based on blood glucose levels, which could transform diabetes care.

SourceIndiana University School of Medicine·JournalProceedings of the National Academy of Sciences·DateAug 2, 2021

Improving amputation surgery

Researchers developed an agonist-antagonist myoneural interface (AMI) that restored physiological feedback, enabling greater precision of movement and reducing pain in amputees. Studies showed improved muscle activity coordination and lower pain levels compared to traditional amputation procedures.

SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateFeb 15, 2021

Bone-anchored leg prostheses also prove to be a valuable procedure after 5-year follow-up

After a 5-year follow-up, bone-anchored leg prostheses show significant improvements in daily functioning, mobility, and quality of life for patients with above-knee amputations. Despite initial stoma problems, these prostheses lead to permanent benefits, including increased prosthesis use and improved health-related quality of life.

SourceRadboud University Medical Center·JournalJournal of Bone and Joint Surgery·DateAug 6, 2020

Mind-controlled arm prostheses that 'feel' are now a part of everyday life

Researchers at Chalmers University of Technology have developed mind-controlled arm prostheses that deliver sensations of touch, revolutionizing prosthetic technology. The new neuromusculoskeletal prosthesis is connected to the user's nerves, muscles, and skeleton, enabling patients with arm amputations to experience a sense of touch i...

SourceChalmers University of Technology·JournalNew England Journal of Medicine·DateApr 29, 2020

Low income is a risk factor for 'catastrophic' amputation after knee joint replacement

A study published in Clinical Orthopaedics and Related Research found that low-income patients are at higher risk of above-knee amputation after periprosthetic joint infection. The researchers analyzed data from a nationally representative hospital database and found that patients living in areas with lower incomes were 58% more likely...

SourceWolters Kluwer Health·JournalClinical Orthopaedics and Related Research·DateApr 30, 2019

Algae could prevent limb amputation

Researchers develop small capsules from brown algae that hold macrophages, increasing blood flow to damaged limbs. The treatment aims to reduce the need for amputations in people with CLI, a condition affecting up to 60,000 new cases per year in the UK.

SourceBritish Heart Foundation·Journalnpj Regenerative Medicine·DateMar 20, 2019

Phantom limb sensation explained

A new study published in Scientific Reports found that brain areas responsible for movement and sensation alter their functional communication after a limb amputation. Researchers discovered that sensitive and motor areas of the brain exhibited abnormal patterns of communication among hemispheres, even in patients without phantom pain.

SourceD'Or Institute for Research and Education·JournalScientific Reports·DateFeb 21, 2019

Amputation injury is communicated to opposing limbs

Scientists at Tufts University have found that amputation of one limb immediately reflects in the bioelectric properties of the opposing, un-damaged limb in developing frogs. The phenomenon, dubbed 'bioelectric injury mirroring,' indicates that information about damage to tissues is available within 30 seconds.

SourceTufts University·JournalDevelopment·DateOct 4, 2018

Brain changes following childhood limb loss may be reversible

A recent study found that certain brain changes following limb amputation in children can be reversed through bilateral hand transplantation. The lead author suggests that the brain preserves functional areas and reactivates them upon recovery of the hands.

SourceWiley·JournalAnnals of Clinical and Translational Neurology·DateDec 6, 2017