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Nanodiamond-enhanced MRI offers greater range of diagnostic and therapeutic applications

Researchers have developed a means of non-invasively tracking nanodiamonds with magnetic resonance imaging (MRI), opening up new applications in disease diagnosis and therapy. The technique uses the Overhauser effect to boost the weak magnetic resonance signal of diamond, allowing for high-contrast imaging over indefinite periods.

SourceMassachusetts General Hospital·JournalNature Communications·DateApr 26, 2017

3-D-printed model of stenotic intracranial artery enables vessel-wall MRI standardization

A collaboration created a 3D-printed phantom of a stenotic intracranial artery to standardize high-resolution MRI protocols for studying intracranial atherosclerotic disease. The phantom enables standardized vessel-wall MRI at multiple sites, facilitating multicenter trials and accelerating research.

SourceMedical University of South Carolina·JournalJournal of NeuroInterventional Surgery·DateApr 14, 2017

Major new issue of CVIA on imaging

The first issue of Volume 2 of Cardiovascular Innovations and Applications (CVIA) has been published with a Special Issue on Imaging. The issue brings together contributions from leading cardiologists and features recent advances in noninvasive cardiac imaging, as well as clinical applications and future directions.

SourceCardiovascular Innovations and Applications·JournalCardiovascular Innovations and Applications·DateMar 22, 2017

Women at high risk for breast cancer more likely to get MRI when informed directly

A study published in Health Communications shows that women at high risk for breast cancer who received a letter informing them of their options for additional imaging with contrast-enhanced MRI were more likely to return for additional screening. The researchers found that direct communication increased follow-up screening rates among...

SourceUniversity of Colorado Anschutz Medical Campus·JournalHealth Communication·DateMar 8, 2017

A new contrast agent for MRI

Researchers have developed new iron oxide nanoparticles with zwitterion coating that can produce similar MRI contrast to gadolinium-based agents without the risk of adverse effects. The particles are water-soluble, compact and biocompatible, making them a potential safer substitute for current contrast agents.

SourceMassachusetts Institute of Technology·JournalProceedings of the National Academy of Sciences·DateFeb 14, 2017

Study discusses model for understanding nutrition and brain development

Researchers at the University of Illinois have developed a piglet model to study nutrition's effects on infant brain development and behavior. The new review article highlights several studies on pediatric nutrition, including those that assess brain development outcomes using advanced MRI methods.

The lasting effects of ministrokes may contribute to dementia

Recent preclinical research suggests microinfarcts can induce prolonged dysfunction in brain areas estimated 12-times larger than the visible injury site, contributing to cognitive decline and dementia. The study used a mouse model to examine the effects of individual cortical microinfarcts on surrounding tissue function in vivo.

SourceMedical University of South Carolina·JournalJournal of Cerebral Blood Flow & Metabolism·DateJan 16, 2017

Visualizing gene expression with MRI

Researchers at Caltech have developed a method to link magnetic resonance imaging signals to gene expression in cells, allowing for non-invasive monitoring of disease. The technique uses aquaporin reporter genes to visualize gene expression in living tissues, with potential clinical translation.

SourceCalifornia Institute of Technology·JournalNature Communications·DateDec 23, 2016

High-precision magnetic field sensing

Researchers developed a high-precision sensor to measure small variations in strong magnetic fields, enabling the detection of mechanical processes in the body. The technique has broad applications in medicine and biological research, including the development of new contrast agents for MRI.

SourceETH Zurich·JournalNature Communications·DateDec 2, 2016

World first MRI study sheds light on heart damage during kidney dialysis

A world-first MRI study has investigated the heart function of kidney patients undergoing dialysis treatment, revealing significant cardiovascular effects with both standard haemodialysis and hemodiafiltration. Both treatments caused falls in cardiac performance, with partial recovery after dialysis, highlighting the need for intervent...

SourceUniversity of Nottingham·JournalJournal of the American Society of Nephrology·DateNov 30, 2016

Researchers identify group of brain structural networks linked to loss of cognitive function

A new study has identified a group of brain structural networks linked to loss of cognitive function, highlighting the importance of cerebral small vessel disease. The research found that certain networks are less affected by age, while others show decreased expression and correlation with impaired cognitive functioning.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalBrain Connectivity·DateNov 2, 2016