Articles tagged with Medical Treatments
The new COBRE grant will help WVU recruit researchers and clinician-scientists to develop innovative solutions for preventing and treating incurable vision problems. The project aims to reduce visual disparities in West Virginia by understanding the complex combination of factors that contribute to these problems.
A study has identified disease mechanisms in children with severe COVID-19, including blood clotting and immune protein pathways. The research found specific proteins involved in multisystem inflammatory syndrome and acute respiratory distress syndrome, which are major potential outcomes of severe COVID-19.
A Rutgers study found that nontraditional 9/11 emergency workers are more than five times as likely to have considered suicide, with 12.5% expressing suicidal ideation compared to 2.2% of traditional first responders. Factors contributing to this disparity include inadequate training and financial hardship.
A study in rural Malawi found high mortality rates for children admitted to hospital with low blood sugar or oxygen levels. The findings suggest that earlier identification and prompt care-seeking could help reduce the risk of death, emphasizing the need for better clinical management of severely ill children.
Researchers at the University of Oxford have demonstrated the efficacy of adalimumab in treating early-stage Dupuytren's disease. The trial found that patients receiving adalimumab experienced softening and reduction in size of treated nodules, with sustained effects up to nine months after treatment.
A new study using a citizen science board of people affected by Long Covid identifies key research areas, including treatment, diagnosis, and disease management. The findings highlight the need for clear diagnoses and access to care that meets their multidimensional needs.
Cancer cells employ a unique defense mechanism to evade the effects of radiation treatment by exploiting an enzyme called Caspase-activated DNase (CAD). Removing CAD from cancer cells increases the effectiveness of radiotherapy. Researchers hope their discovery can lead to the development of targeted drugs to enhance cancer treatment.
A study found that pediatric transplant patients attend on average less than one appointment per year after transferring to adult care, resulting in longer hospital stays and poorer health outcomes. Maintaining regular appointments is crucial for continued transplant success, according to the researchers.
A study from the Healthy Nevada Project found that only 10% of patients with electronic health records containing genetic diagnosis experienced a change in care, emphasizing the need for follow-up education and conversations. The study also highlights the importance of including genetic diagnoses into electronic health records to maxim...
A UK study of over 2,000 COVID-19 patients found that only around 25% feel fully recovered after one year. Women and obese individuals are more likely to experience lower recovery rates. The study highlights the need for effective interventions to address long-term symptoms and improve patient care.
A study of 8,900 patients in New York State hospitals revealed racial and ethnic disparities in pain treatment for obstetric patients. Obstetric patients in minority groups were less likely to receive an epidural blood patch (EBP) for postdural puncture headache during delivery hospitalization.
A doctor's visit from the future describes patient care in 2042, where diagnosis and treatment are personalized based on individual biological abnormalities. Researchers believe this approach could lead to more effective treatments for neurodegenerative disorders.
A survey of veterinarians in the US and Canada reveals a significant increase in cannabis poisoning cases among pets since Canada's 2018 legalization, with most cases treated successfully. The study highlights the importance of understanding the effects of cannabis on pets to inform veterinary efforts and policies.
A study led by MUSC researchers found that inhibiting the complement system with CR2Crry can prevent long-term brain damage and improve outcomes in premature infants with germinal matrix hemorrhage. The treatment has shown improved survival, weight gain, reduced brain injury, and enhanced motor and cognitive performances.
The UK National Osteoporosis Guideline Group has published a new guideline for the prevention and treatment of osteoporosis, which includes updated recommendations for vertebral fracture detection and anabolic treatment options. The guidance aims to improve service provision in both primary and secondary care settings.
Researchers at Karolinska Institutet study how the immune system protects against malaria, finding that people who have contracted the disease before develop a tolerance that prevents severe disease. This knowledge can aid in the development of more effective vaccines.
A new Michigan Medicine study found that for children with a pelvic tilt and lower lumbar spine tilt of fewer than 10 degrees, the pelvis did not need to be included when inserting growing rods. This could help avoid painful complications such as skin breakdown and infection.
Researchers studied two strains of Mycobacterium tuberculosis with different lung attack mechanisms, finding that high-transmission strains trigger granulomas that may aid bacterial escape into the airways. In contrast, low-transmission strains cause inflammation that traps bacteria, reducing transmissibility.
Researchers at Tokyo University of Science discovered that disulfiram inhibits FROUNT protein and chemokine signaling pathways, reducing anxiety levels in mice. The study suggests a potential breakthrough anti-anxiety medication with safe and effective treatment for elderly patients suffering from anxiety and insomnia.
A survey found that individuals experiencing food insecurity were twice as likely to delay or forego medical care due to cost concerns. Food insecurity disproportionately affected racial and ethnic minority groups, low-income individuals, and those who lost their jobs or income.
A new study by researchers at the University of Birmingham has identified two distinct brain structure patterns associated with poor outcomes in patients with recent onset psychosis and depression. The study used MRI scans to analyze grey matter volume and found that lower volumes were linked to poorer outcomes, while higher volumes we...
Current guidelines for treating women's obesity, hypertension and diabetes are based on men's studies. Researchers call for sex-specific guidelines to accurately treat these conditions in women, as they have different risk factors and manifestations.
A new study shows that the telestroke program prevents unnecessary hospital transfers for stroke patients, decreasing rural healthcare disparities. The program increases care efficiency and cost-effectiveness, while optimizing care for patients.
Researchers from Goethe University and University of Kent found aprotinin effective against SARS-CoV-2 variants, including Delta and Omicron, by preventing virus entry into host cells. A recent phase III clinical study demonstrated the treatment reduced hospital stays by five days.
A new study reveals funding for fertility preservation policies varies across the UK, with Scotland offering the most inclusive approach. The study highlights the need for standardization of policies to ensure equal access to care for patients.
A study published in the Journal of Alzheimer's Disease Reports suggests that damage to the blood-brain barrier is the determining cause of Alzheimer's disease. The Lipid Invasion Model proposes that lipids entering the brain due to barrier damage lead to brain shrinkage, amyloid plaques, and tau tangles, characteristic of the disease.
A recent UCLA study found that the injury rate for e-scooter riders in Los Angeles is higher than the national rates for motorcycle, bicycle, car, and pedestrian injuries. The study estimates 115 injuries per 1 million e-scooter rides, highlighting a growing risk as e-scooters proliferate globally.
The study found significant improvements in blood flow through the heart and quality of life at one year, with all 36 patients achieving a reduction in tricuspid regurgitation severity. Longer follow-up is needed to determine how well the device continues to perform.
A randomized clinical trial comparing FFR-guided and IVUS-guided PCI found similar outcomes for patients with intermediate coronary artery stenosis. Patients evaluated by FFR underwent fewer stents but had similar rates of adverse events and improved quality of life.
A study found that implantable heart monitors do not reduce cardiovascular events overall, but patients with non-ST segment elevation myocardial infarction (NSTEMI) heart attacks saw strong benefits. Monitoring for abnormal heart rhythms may help guide care for NSTEMI patients.
Researchers found a significant decline in in-hospital mortality and secondary endpoints for STEMI patients with COVID-19 in 2021 compared to 2020. Vaccination status showed zero hospital deaths among vaccinated patients, while unvaccinated patients experienced high death rates.
A study in rats suggests that vitamin C supplementation can help preserve skeletal muscle after doxorubicin therapy, reducing oxidative stress and inflammation. The findings suggest vitamin C may represent a promising opportunity to reduce some of the drug's most debilitating side effects.
A study presented at the American College of Cardiology's Annual Scientific Session found that personalized nutrition education in grocery stores significantly improved DASH diet adherence. Participants who received six one-on-one sessions with a dietitian showed an average increase of 4.7 points on their DASH scores.
A new study suggests that cardamonin, a compound from the cardamom spice, can kill triple-negative breast cancer cells and reduce PD-L1 expression. The findings hold promise for improving cancer therapy without severe side effects.
Researchers developed an algorithm to classify 16 distinct adult sleep patterns based on arm acceleration data from 100,000 UK Biobank participants. These patterns can be used to diagnose insomnia and develop personalized treatment methods, offering new insights into human sleep behavior.
A new collaboration between UW Oshkosh and Fauna Bio aims to translate animal disease resistance into human treatments. The partnership will enable researchers to study emerging animal models, such as the 13-lined ground squirrel, to develop novel therapeutic programs.
H. Alex Choi receives NIH grant to develop protein biomarkers for delayed cerebral ischemia, a complication after subarachnoid hemorrhage that affects approximately 50,000 Americans annually. The goal is to predict which patients will worsen and identify biological processes causing worsening patients.
Researchers at Okayama University have created a new method to kill cancer cells using light-activated protein AR3, reducing the risk of adverse reactions. The approach uses green light to trigger apoptosis in targeted cells, offering a promising alternative to conventional treatments.
A new treatment approach has been proposed for children with congenital muscle disorders, using inhibitors to improve muscle function and movement in mice with mutations in the RYR1 gene. The therapy targets genetic material overload caused by excessive enzyme production, leading to reduced access of genes to cellular machinery.
Researchers at UVA Health System discovered a cluster of cells in the brainstem that controls the body's response to severe blood loss. The study found that re-activating these neurons can restore blood pressure and heart rate in lab rats, offering new hope for treating traumatic injuries.
Researchers at Boston University have developed optoacoustic neurostimulation with single neuron and subcellular level precision. Optoacoustic neuromodulation may offer advantages over ultrasonic neuromodulation, including higher spatial temporal resolution.
A report by the British Pharmacological Society and Royal College of Physicians recommends integrating pharmacogenomic testing to ensure medicines work safely and effectively for individual patients. The UK is a world leader in genomic medicine, and expanded testing would further demonstrate this leadership.
The Experimental Biology (EB) 2022 meeting features live presentations and a moderated Q&A session on groundbreaking studies. The virtual press conference reveals potential treatments for Parkinson's disease, COVID-19 vaccine-associated side effects, and alleviating food allergies.
In an animal study, researchers created an implantable biotechnology called MASTER that produces and releases CAR-T cells for attacking cancerous tumors. This technology reduces the manufacturing time from weeks to hours, increasing efficiency and effectiveness.
Research found that IVF clinics offering money-back guarantees have a higher live-birth success rate and lower multiple birth risks compared to those without MBGs. The study suggests that these programs serve as signals of high-quality care in the field of IVF and other healthcare services.
A study found that 42% of TikTok videos on high blood pressure focused on alternative medicine, while only 5% mentioned exercise. Most creators were not healthcare professionals, highlighting the need for more emphasis on credible sources.
Researchers have identified a new family of proteins in blood vessels that prevent fluid from entering the lungs, offering a potential new avenue for treating acute respiratory distress syndrome. Stimulating these bitter taste receptors has been shown to provide protection against fluid leak into the lung.
A study found that 25.3% of children with mild head injuries continue to suffer from persistent post-concussion syndrome for years, often misdiagnosed as ADHD or sleep disorders. The syndrome causes chronic symptoms like forgetfulness, memory problems, and sensitivity to light and noise.
A recent study found that approximately 1 in 3 heart attack survivors experience significant mental decline in the days and months following their heart attack. Cognitive deficits can impact quality of life and treatment adherence, emphasizing the need for cardiologists to monitor patients regularly.
The American College of Chest Physicians journal features cutting-edge original research on various chest medicine topics, including asthma, COPD, critical care, and sleep. The March issue includes a special series on nontuberculous mycobacterial pulmonary disease, offering insights into clinical epidemiology, risk factors, and diagnosis.
Researchers found that obstructive sleep apnea (OSA) accelerates the biological aging process and causes epigenetic age acceleration, leading to increased mortality risk. However, one year of CPAP treatment significantly slows down biological age acceleration in OSA patients, suggesting a potential reversal of age-related trends.
Researchers found that four-month treatment is as effective as six months in non-severe TB cases, allowing for savings on screening and training healthcare workers. The study's results led to a change in the World Health Organisation's global guidelines, recommending a shorter treatment course for children with non-severe TB.
A study of 1,164 patients with COVID-19 found that continuing dexamethasone treatment at hospital discharge was associated with lower readmission rates and mortality within 14 days. The treatment also showed significant benefits in reducing the risk of severe disease progression.
The World Congress on Osteoporosis, Osteoarthritis & Musculoskeletal Diseases (WCO-IOF-ESCEO) 2022 will discuss secondary fracture prevention. Global experts will provide clinical guidance and information on post-fracture care through various sessions.
A team of UTSA researchers has developed an innovative inhibitor that blocks the effects of cytochrome P450 8B1, a key enzyme linked to cholesterol absorption and obesity. The treatment shows promise in reducing glucose levels without affecting body weight, offering potential relief from obesity-associated metabolic disorders.
Researchers analyzed mortality rates and complications among 5,500 COVID-19 patients treated at dedicated vs non-dedicated hospitals in Minnesota. The study found no significant difference in outcomes between the two types of hospitals.
Researchers at University of Texas at Austin create first-ever biologically authentic computer model of HIV-1 virus liposome, shedding light on replication and infectivity. The study reveals key characteristics of the liposome's asymmetry and its role in shaping macroscopic properties.
Researchers found that it took nearly three years for these drugs and biologics to be incorporated into clinical guidelines, highlighting a significant delay in patient access. The study suggests that expedited approval processes are only the first step, and planning ahead is crucial to bring needed treatments to patients.
Researchers at MIT have performed a systematic study on how different-sized polymer nanoparticles circulate in the body and interact with platelets to stop bleeding. They found that intermediate-sized particles (150 nanometers) were the most effective, with less likelihood of accumulating in off-target sites.
Researchers have made a significant breakthrough in predicting heart attacks and strokes by developing a non-invasive method using super-resolution ultrasound imaging. The technology aims to detect high-risk atherosclerotic plaques that are prone to rupture, allowing doctors to prescribe life-saving interventions.