Research on therapies used across medicine and how they perform. Covers weight-loss injections, hormone therapy, stem-cell approaches, pain relief, and drug targets.
Researchers used mathematical modeling to better understand the causes of debilitating diseases like glaucoma, which could lead to more efficient treatments. The model helps doctors measure blood flow and oxygen levels in fine detail, improving their ability to treat root causes.
A team of researchers at the University of Manchester has found a novel solution to reducing inflammation by harnessing the power of hypertonic solutions. They discovered that bathing in or applying these solutions can shrink cells and deactivate the inflammatory response.
Researchers investigated three strategies for adjusting asthma therapy in adults with mild to moderate persistent asthma. The study found no significant differences in treatment failure rates among the groups, including those based on physician assessment, biomarkers, or symptom occurrence.
Researchers analyzed 70 press releases and 41 associated news stories, finding that 33 contained 'spin' in press releases and 28 in study abstracts, potentially leading readers to overestimate treatment benefits.
A study published in Neurosurgery found that women with moyamoya disease are at higher risk of adverse outcomes, including stroke, after surgical treatment. Despite this, both men and women experience significant improvements in health and functioning after surgery.
The fungi treatment process modifies the acoustic properties of the instrument, making it sound indistinguishably similar to a Stradivarius. The research could soon make high-quality wood available for violin making.
A new study found that untreated severe obstructive sleep apnea (OSA) increases cardiovascular mortality in the elderly. However, adequate continuous positive airway pressure (CPAP) treatment significantly reduces this risk, especially from stroke and heart failure.
The ACCESS-EU study found significant clinical improvements in patients treated with MitraClip therapy, including reduced death rates, mitral regurgitation, and need for surgery. The study's results confirmed the effectiveness of the device in a real-world setting.
The Wilderness Medical Society has released new guidelines to prevent and treat lightning injuries, with recommendations for effective medical treatments post-strike. These guidelines aim to lower the likelihood of being killed or injured from lightning strikes.
Increased copeptin levels are associated with increased frequencies of comorbidities, severity of heart failure, and risk of all-cause death. Copeptin measurements link to the strength of cardiac contractility and predict poorer kidney function. The risk of mortality from all causes increases with rising copeptin levels.
A study found that commercial drivers with sleep apnoea reported lower levels of daytime sleepiness despite similar night-time disturbances. The drivers also received less treatment and made more unscheduled visits to the clinic, suggesting they were struggling with their symptoms.
A new study links nasal irrigation with contaminated tap water to rare disease Naegleria fowleri infections. The Centers for Disease Control and Prevention reports two fatal cases in Louisiana where the organism was found in home water systems, highlighting the importance of using safely treated water for sinus irrigation.
A new study published in the Pediatrics Journal found that montelukast significantly improved respiratory disturbance and adenoid size in children with obstructive sleep apnea. The study showed a 50% decrease in obstructive apnea index in 65% of treated children.
A study published in JAMA found that couple's therapy, specifically cognitive-behavioral conjoint therapy (CBCT), can significantly decrease PTSD symptom severity and improve intimate relationship satisfaction in couples. The treatment was more effective than a wait-list condition, with improvements maintained at a 3-month follow-up.
A study found that deeply held religious beliefs are leading to futile care for sick children, causing needless suffering. Doctors argue that parental hopes of a 'miraculous intervention' should not override the child's best interests.
A cluster randomized trial found that pay for performance improved demonstration of competency in treatment delivery and increased the number of patients receiving targeted treatment procedures. However, no statistically significant difference was found in patient remission status between the two groups.
A Johns Hopkins review of over 38,000 patient records reveals that weekend hospital stays are associated with a higher mortality rate for older adults with head trauma. Even among patients with less severe injuries, weekend admissions resulted in 14% higher death rates compared to weekday admissions.
Research on Alzheimer's disease is gaining momentum, with over 150 companies working on innovative approaches to tackle the debilitating disease. New therapies, such as Antisenilin and Gammagard, are in Phase III trials and show promise in addressing the underlying biology of the disease.
A University of Michigan Health System study found that women with vulvodynia are at a higher risk for other chronic pain conditions. The study showed that millions of women suffer from unexplained vulvar pain that can severely impact daily life.
A novel intervention called Emotion Detectives Treatment Protocol (EDTP) has shown significant reductions in anxiety and depression severity after treatment. The program adapts age-appropriate techniques from adult and adolescent protocols to educate children about emotions, problem-solving skills, and behavior activation.
A new telephone-based motivational interviewing technique effectively increased treatment engagement among Iraq and Afghanistan war veterans with mental health diagnoses, reducing marijuana use and stigma. The study found that 62% of participants started treatment after receiving the intervention.
The newly established Therapeutic Innovation Australia Queensland Node will provide a testing model to speed up the movement of inventions from laboratory to therapeutic products. The Node will focus on four initial projects, including migraine prevention and diabetes management, aiming to deliver tangible commercial returns within fiv...
Dr. Nihal Altan-Bonnet, a Rutgers cell biologist, has been awarded the Presidential Early Career Award for Scientists and Engineers (PECASE). Her research identifies a common lipid blueprint for viral replication, paving the way for potential panviral therapeutics.
A team of scientists has developed low-lactose functional milk enriched with American ginseng, which maintained beneficial levels after processing. The product was well accepted by a niche group of consumers, particularly those interested in the health benefits of ginseng.
A study found that YouTube videos showing the Epley maneuver, a simple treatment for BPPV, are highly accurate and widely used by healthcare providers and people with vertigo. The videos have also helped to educate patients about how to treat this disorder.
Researchers study Bolivian and Paraguayan families' medical travel experiences seeking pediatric oncology care in Argentina. Medical travel can be a strategy for economically challenged patients to save their lives, but it also carries challenges like relocation uncertainty.
Research by Jesus Lovera and colleagues found that stress management therapy prevented new brain lesions in people with multiple sclerosis, with 77% of patients remaining free of lesions. The benefit did not continue beyond treatment, highlighting the need for longer therapy or continued support.
A new treatment protocol, Emotion Detectives Treatment Protocol (EDTP), shows significant reduction in anxiety and depression severity after treatment. The program delivers education about emotions, strategies for evaluating situations, problem solving skills, behavior activation, and parent training.
A study analyzing published data found that vertebroplasty provides better pain relief and function for patients with osteoporotic vertebral compression fractures compared to nonoperative treatments. Vertebral stabilization technique also offers benefits over other treatments despite conflicting results to date.
A study published in Archives of Neurology found that patients with stroke admitted on weekends received fewer urgent treatments and had higher mortality rates compared to weekday admissions. The study suggests that hospitals could potentially save hundreds of lives by improving care on weekends.
EP67, a powerful synthetic protein, is able to activate the innate immune system within two hours of administration, preventing flu symptoms. The study found that EP67 functions similarly across different flu strains, offering a promising alternative to traditional vaccines.
Researchers have identified the interfascicular matrix (IFM) as essential for tendon function, suggesting it may be critical in preventing tendon overuse injuries. The finding has significant implications for understanding and treating tendon disorders that cost the UK economy billions of pounds annually.
A study found that higher public reimbursement for fertility treatment increases access to care, reducing unmet needs in subfertile populations. Countries with more generous funding policies have a higher volume of ART cycles performed and lower rates of multiple births.
A study published in Neurology found that botulinum toxin injections significantly improved tremor severity and writing/drawing abilities in people with multiple sclerosis. The treatment also showed promise in reducing muscle weakness after treatment.
The American Psychiatric Association Task Force on Treatment of Gender Identity Disorder recommends clinical practice guidelines for psychiatrists caring for transgender patients. The report concludes that the quality of research evidence is not robust, but clinical consensus supports treatment recommendations.
IVF and ICSI technologies have reached a calculated total of 5 million births worldwide since 1978. The cumulative total has increased by nearly 10% this year, with over 1.5 million treatment cycles performed globally annually, producing around 350,000 babies.
A Michigan State University professor and colleague discuss the importance of plant research in a paper published in Science. They highlight the need to improve our understanding of plant metabolism to develop more sustainable agriculture and medicinal products.
A massive study of nearly 250,000 U.S. women found that live birth rates for fertility treatment can approach natural fertility rates with favorable patient and embryo characteristics. The study highlights the importance of factors such as age and embryo quality in determining success rates.
A stepped-care approach to weight loss resulted in clinically meaningful weight loss with lower costs compared to a standard behavioral weight loss intervention. The study found that the stepped-care intervention was more cost-effective, with a mean cost per participant of $358 compared to $494 for traditional programs.
Autism Speaks releases three new tool kits to help parents manage challenging behaviors, improve communication and social skills. The kits provide guidance on applied behavior analysis, professional behavioral treatments and toilet training strategies.
A new study suggests that Coenzyme Q10 reduces oxidative damage in patients with Huntington's disease, hinting at its potential to slow progression. The discovery also identifies a new biomarker, 80HdG, which could be used to screen experimental treatments for this and other neurological disorders.
Saskia B. Neher, a UNC School of Medicine assistant professor, is one of 22 promising scientists to receive the 2012 Pew Scholars award, supporting her research on LPL regulation and its implications for cardiovascular disease.
Research shows that CPAP therapy significantly improves sexual function and satisfaction in men with sleep apnea, regardless of their initial level of erectile dysfunction. The study found robust improvements in the majority of participants, including those with ED.
Advanced time-lapse imaging techniques show promise for increasing IVF success rates by selecting high-quality single embryos for transfer. Reliable assessment of embryonic quality could reduce emotional costs and improve procedure efficiency.
Roughly 28% of low-income HIV-positive pregnant women reported depression, with African-American women facing barriers to care due to mistrust and unequal quality of care. Untreated depression poses significant risks to both mothers and fetuses, highlighting the need for targeted screening and treatment strategies.
A team of researchers has identified a hereditary enzyme deficiency, MPS IIIE, which leads to cognitive decline and learning difficulties in mice. The discovery also sheds light on the role of heparan sulfate degradation in lysosomal storage disorders.
The prevalence of Type 1 diabetes among young people in the US has increased by 23% between 2001 and 2009, according to a new study. Researchers funded by organizations like JDRF are making progress in treatments, technology, and vaccines, but more support is needed to combat this life-threatening disease.
A molecular imaging study shows that ASV can improve cardiac function, exercise capacity, and sympathetic nerve activity in patients with congestive heart failure. The therapy was found to be just as effective as conservative treatments in reducing symptoms and improving overall health.
Researchers found nearly half of students with poor sleep also reported a fear of the dark. To treat this condition, new approaches may be needed to address the underlying phobia rather than just treating insomnia symptoms.
Baricitinib demonstrates dose-dependent efficacy in active rheumatoid arthritis, with 76% of patients achieving ACR20 response compared to 41% on placebo. Patients also showed significant improvements in disease activity and functional outcomes.
A recent study published at EULAR 2012 found that obese patients with psoriatic arthritis have a lower chance of achieving minimal disease activity when treated with anti-TNFs. However, following a hypocaloric diet can increase the likelihood of achieving treatment goals.
Developing a reliable measure of mental illness stigma in adolescents is crucial for encouraging teens to seek help. A study published in the Journal of Nursing Measurement found that the Revised Attribution Questionnaire (r-AQ) can be considered reliable and valid for assessing stigma among this age group.
The US Army has implemented a behavioral health screening program in primary care, resulting in improved PTSD outcomes. The program, RESPECT-Mil, has doubled the number of patients experiencing clinically significant reduction in PTSD symptom severity scores over eight weeks.
A new study demonstrates that a back brace with a tiny heat sensor can measure how long it is worn, leading to improved compliance rates among children. The Thermobrace system shows promising results in tracking brace wear and fostering better patient-physician relationships.
A follow-up NIH study confirms that hypothermia treatment increases infant survival, without increasing long-term disability risk. Children who received the cooling technique were more likely to survive to ages 6 and 7 compared to those who received routine care.
The International Osteoporosis Foundation predicts a significant rise in hip fractures in Brazil, projected to increase by 32% by 2050. This is largely attributed to the aging of the Brazilian population, with over 37% expected to be over 50 years old and 14% over 70 years old by then.
A new study found that weight loss significantly improved both sleep-disordered breathing (SDB) and metabolic dysregulation in obese children. After a six-month weight loss program, mean BMI was reduced to 29.2 kg/m2, leading to improvements in ASAT, ALAT, HDL-cholesterol levels.
Prior ICS treatment before CAP diagnosis is associated with lower incidence and severity of parapneumonic effusion. Patients treated with ICS had a significantly lower risk of developing this complication, regardless of their baseline chronic respiratory condition.
A study found that children with mild persistent asthma benefit from ICS treatment, but some groups benefit more than others. Younger children, non-Hispanic kids, those with eczema and high IgE levels experience greater benefits from ICS treatment.
A new study found that treating childhood OSA normalizes brain disturbances responsible for attention and executive function. Brain imaging showed improvements in verbal memory, attention, and frontal cortex metabolites after treatment.