Articles tagged with Affective Disorders
Approximately 1 in 5 adolescents had major depressive disorder, with less than half receiving mental health treatment. Racial and ethnic minority groups, particularly Latinx, experienced the lowest treatment rates.
A new study found that depression risk in adolescents varies between boys and girls, with different cytokines linked to depression severity in each sex. In boys, higher levels of interleukin-2 were associated with increased risk and severity of depressive symptoms.
A randomized clinical trial of psilocybin treatment found a clinically significant sustained reduction in depressive symptoms and functional disability. The study's findings support the potential of psilocybin as a novel intervention for major depressive disorder when administered with psychological support.
A study of 1.3 million people found that those with hospital-treated depression have a high risk of developing conditions like bipolar disorder, schizophrenia, and anxiety disorders. Genetic analysis also revealed a link between depression and reduced cognitive abilities, such as abstract thinking and mental flexibility.
Researchers found that wildfire smoke triggers chronic brain inflammation affecting learning and memory regions, lasting up to 28 days. The study's findings are concerning given the frequent exposure of people to wildfire smoke.
Researchers propose GABA-modulating treatments as potential therapeutic targets for depression's cognitive and affective symptoms. The study highlights the importance of GABA-A receptors in regulating balance and signals between neurons, and suggests compounds that promote or inhibit these receptors may alleviate depressive symptoms.
Researchers identified three neurobehavioral profiles that distinguish individuals with elevated mania vulnerability based on reward sensitivity and sleep-circadian characteristics. These profiles can help detect mania risk and provide targets for early interventions.
Research from University of Limerick reveals that even moderate daily physical activity can lower the risk of depressive symptoms and major depression among older adults. Studies showed that doses equivalent to 20 minutes a day of moderate-intensity physical activity were associated with reduced risk of depression, highlighting the imp...
A study published in PLOS ONE found that equine-facilitated psychotherapy significantly improves the lives of patients struggling with substance use disorders. The therapy, which involves horses, has been shown to boost mood and overall well-being.
Researchers have identified a subtype of depression, labeled the cognitive biotype, which accounts for 27% of depressed patients. This group has difficulty with planning, self-control, and focus, and shows reduced activity in brain regions responsible for these tasks. Targeting cognitive dysfunctions with less commonly used antidepress...
A large Danish study suggests that cannabis use disorder is associated with an increased risk of developing depression and bipolar disorder. The research analyzed data from over six million individuals and found a two-to-three-times higher risk of developing bipolar disorder in both men and women.
Scientists have identified distinct mechanisms by which people remove information from their working memory and found that forgetting requires much effort. They also discovered four brain networks that activate when memories are maintained or purged through different mechanisms.
A new study reveals that childhood emotional trauma and sexual abuse are strongly associated with psychiatric symptoms in women, while childhood emotional and physical neglect increase the risk of symptoms in men. The research analyzed data from over 791 volunteers worldwide.
A new study has found that increased rumination is a predictor of greater severity of suicidal ideation in young people with major depressive disorder. The study, published in the Journal of Affective Disorders, suggests that elevated cognitive rumination is associated with lower cortical surface area and suicidal ideation.
Research suggests that participants in psychology studies are more likely to exhibit symptoms of personality disorders, which could impact the validity of study results. The prevalence of these disorders may be due to self-selection biases in participant recruitment.
Primary care physicians recommend screening adolescents and young adults for cyberbullying and social media misuse, citing the need for timely intervention due to underreported incidents. Screening tools like R-OBVQ, CBVS, CABS, and MARC can help identify potential risks.
Researchers found that loneliness is a major risk for mental health problems during pregnancy and after birth, with stigma, self-isolation, and emotional disconnection contributing factors.
A nationwide Finnish study found that around 58% of people with low educational attainment by age 30 will have a diagnosis of a mental disorder by age 52. The study also showed a stronger association between lower socioeconomic position and later diagnoses of substance misuse or schizophrenia spectrum disorders.
A study of 1,463 combat-deployed soldiers found significant associations between bullying/hazing and major depressive disorder, PTSD, suicidal thoughts, and substance use disorder. The findings highlight the need for efforts to prevent and address mental health problems among service members.
A new study published in JAMA Network Open found that patients with depression are less likely to adhere to essential medical therapies following percutaneous coronary intervention (PCI). The study examined over 124,000 patients who underwent PCI and were diagnosed with depression, revealing a significant proportion of individuals with...
Researchers found that experiences of early deprivation, such as parental neglect and financial difficulties, were more closely associated with cognitive and emotional functioning in adolescence. Deprivation was also linked to internalizing and externalizing problems, including lower performance on tests of intelligence.
A major birth cohort study reveals that children exposed to traumatic events, such as witnessing death or serious injury, are almost twice as likely to develop psychiatric disorders. By age 11, over a third of the children had been exposed to trauma, associated with a wide range of mental health problems.
A study of over 17,000 first-year medical residents found a strong correlation between hours worked and depression symptoms. Working long hours was associated with a larger rise in depression symptoms, pushing some residents into moderate or severe depression.
A comprehensive review of research on serotonin and depression found no link between the two, contradicting long-held theories. The study suggests that antidepressants' effectiveness may be due to managing stressful life events rather than correcting chemical imbalances.
A new study published in Behavior Genetics found that natural selection favors characteristics associated with lower earnings and poorer education, such as having more children. The research, led by UEA, analyzed data from over 300,000 people in the UK and suggests that this may be contributing to increasing income inequality.
The study found that the adapted version of the Re-Engineered Discharge (RED) Program, RED for Depression (RED-D), reduced hospital readmissions among patients with depressive symptoms by 48% and 70% at 30- and 90-day marks. The program included post-discharge depression treatment and transition support.
Researchers have demonstrated the efficacy of a six-week interpersonal emotion regulation (IER) intervention for addressing depression often experienced by individuals with multiple sclerosis. IER strategies, such as turning to others for emotional support, significantly reduced depression levels in the treatment group.
Adults exposed to chronic parental domestic violence have higher rates of depression, anxiety disorders, and substance abuse, but many thrive despite their early adversity. Social support plays a crucial role in maintaining good mental health.
A new study published in PLOS ONE finds that high and very high cardiovascular risk are associated with depressive symptoms, especially in women. The researchers used data from a Mediterranean Diet trial and found that participants with higher cardiovascular risk had lower depressive status scores after following the diet.
A new study found that integrating behavioral health into pediatric primary care at federally qualified health centers increases access, timeliness of care, and diagnostic rates of ADHD among diverse children. The model resulted in higher follow-up rates with behavioral health clinicians and reduced polypharmacy.
Researchers found that maternal post-traumatic stress disorder (PTSD) severity in early childhood predicts child somatisation at school age. The study highlights the importance of considering family trauma history in pediatric consultations to improve patient care.
A recent brain imaging study has found evidence of weakening connections between key brain areas in adolescents at high genetic risk of developing bipolar disorder. This study suggests that early intervention strategies may be effective in preventing the progression towards major changes in the brain.
A recent study published in JAMA Psychiatry has found that individuals without jobs or stable housing experience worse depression symptoms when treated with therapy or antidepressants. The researchers analyzed data from nine studies involving over 4,800 participants and discovered that unemployed patients had 28% poorer outcomes compar...
A research team developed an algorithm that instantly assesses and adjusts brain stimulation placement using electroencephalography (EEG) feedback. The method can find the optimal stimulation parameters in just 1-2 minutes, potentially improving the efficacy of TMS treatment for brain disorders like chronic pain and depression.
Researchers at Lancaster University developed a prototype that monitors brain signals while colouring mandalas, providing real-time feedback on mindfulness levels. The study found that technology could support emotional memory reflection and recolouring of completed mandalas.
A new study reveals that social isolation and loneliness can increase cardiovascular disease risk by 8% and 5% respectively. Women who experience high levels of both social isolation and loneliness have a 13-27% increased risk of heart disease, compared to those with low levels.
Forced family separation on the US-Mexico border led to a high incidence of PTSD, depressive, and anxiety disorders in asylum-seeking children and parents. Reunification did not alleviate these symptoms, highlighting the need for continued support and intervention.
A study of 2.5 million people found lower COVID-19 infection rates among those with schizophrenia and mood disorders, but higher death rates. The analysis suggests that underlying mental health conditions may impact COVID-19 outcomes.
Children of depressed parents are more likely to develop depression and poor academic performance, according to a new study published in PLOS ONE. The study found that both maternal and paternal depression have significant effects on children's mental health and educational outcomes.
Researchers found a significant rise in Instagram posts with hashtags related to self-injury, with nearly 110,000 posts in December compared to 58,000 at the start of 2018. The study also showed a connection between self-injury and depression, as well as suicide, highlighting the need for effective coping strategies and online monitoring.
Researchers developed a method to image lithium in living cells, finding that neurons from bipolar disorder patients accumulate higher levels of lithium than healthy controls. This new tool could help optimize lithium dosage and improve treatment outcomes for patients with bipolar disorder.
A new study by UCL researchers has found that staying on long-term antidepressants reduces the risk of relapse by 39% compared to those who stop taking them. The study involved 478 primary care patients and found that 56% experienced a relapse within a year if they discontinued their medication, while only 26% did so after a full year.
Researchers conducted a new trial to adapt Dialectical Behaviour Therapy (DPT) for people with frequent Bipolar mood swings. The study aimed to evaluate the feasibility and acceptability of this adapted therapy, finding that it has demand from individuals with Bipolar disorder.
Researchers found that cannabis use disorder is significantly associated with older age, male sex, black race, bipolar or other mood disorders, prior history of self-harm, and previous mental health service use. Cannabis use can worsen symptoms and interfere with successful mood disorder treatment.
A new study by the University of Turku suggests that premature babies are three times more likely to be diagnosed with reactive attachment disorder. The risk is also associated with low birth weight and monitoring in a Neonatal Intensive Care Unit.
A study of nearly 4,000 US Army soldiers found that 11.7% experienced suicidal thoughts at some point in their lives, with a peak risk period during the midpoint of deployment. Risk factors included being white, past noncombat trauma, and major depressive disorder.
Researchers found that specific patterns of brain connectivity were associated with the development of attention-deficit/hyperactivity disorder (ADHD) and major depressive disorder. By examining brain architecture at age 7, the study identified potential links between brain development and later mental health symptoms in children.
A randomized clinical trial examined two nutritional strategies: multinutrient supplementation and food-related behavioral activation therapy. The combination of both strategies showed promise in preventing new episodes of major depressive disorder among overweight and obese adults over one year.
A study of 61 popular mental health apps found they predominantly addressed anxiety and stress, framing problems as psychological symptoms. The analysis suggests these apps may be misleadingly simplistic in their approach to mental health issues.
A large-scale study in Northern Ireland found that children of married first cousins were more likely to receive medicine for common mood disorders and psychoses. The study, which analyzed data from over 363,000 individuals, suggests a potential link between consanguineous relationships and mental health outcomes.
A new study published in Pediatrics found that children with both autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are at a higher risk of developing anxiety and mood disorders. The study, which analyzed data from over 3,300 children, revealed that these psychiatric conditions were more prevalent in ol...
Researchers identified an association between a specific SLC6A15 polymorphism and resting-state brain function in multiple brain regions in patients with MDD. The study suggests a potential genetic link to the development of major depressive disorder.
A recent study found that 3.3% of all emergency department visits were avoidable, with the top causes being alcohol abuse, dental disorders, and depressive disorders. Increasing access to dental and mental health facilities could reduce these visits, providing treatment at a lower cost elsewhere.
A study published in JAMA Psychiatry suggests that reducing nicotine content in cigarettes can decrease their addictiveness in vulnerable populations. The research team found that low-nicotine dose cigarettes could serve as economic substitutes for higher-dose commercial-level nicotine cigarettes when the cost of the latter was greater.
A recent study published in the American Journal of Psychiatry found that valbenazine can significantly reduce tardive dyskinesia symptoms in patients with schizophrenia, schizoaffective disorder, and mood disorder. The medication showed a 50% improvement rate compared to the placebo group.
Research highlights the complex etiology of psychiatric polypharmacy, which can increase the risk of adverse effects and mortality. However, certain populations may benefit from combination therapy, emphasizing the need for tailored prescribing strategies to improve treatment efficacy.
A new study has found that gay and lesbian Canadians experience more mood and anxiety disorders than other Canadians, with bisexual Canadians reporting the highest rates. The research is based on data from over 220,000 Canadians who participated in the Canadian Community Health Survey between 2007 and 2012.
Staff at South London and Maudsley NHS Foundation Trust have reduced waiting times for mental health patients after redesigning their referral system. The results show an improvement in both waiting times and percentage of patients seen within set standards following a single intervention.
An international survey of mental health disorders and their association with chronic physical conditions found a significant link between the two. The study identified 16 mental health disorders and 10 chronic physical conditions, suggesting that mental disorders can increase the risk of developing these conditions.
An international team of researchers has identified two robust genetic variants associated with major depressive disorder (MDD). The study, published in Nature, found that these variants are located on chromosome 10 and may be linked to mitochondrial function.