Articles tagged with Internal Medicine
Researchers at the University of Tokyo have developed a pill-shaped device that can collect samples from the small intestine using a tiny extendable brush. The device is designed to be magnetically controlled, allowing it to move through extracted intestines and sweep useful samples from the intestinal surface. The technology has the p...
Researchers found that host immune status significantly influences herpesvirus retinitis phenotypes and clinical outcomes. Acute retinal necrosis (ARN) is associated with a higher risk of retinal detachment, while cytomegalovirus retinitis (CMVR) follows an indolent course.
A systematic review and meta-analysis found that approximately 40% of patients with chronic pancreatitis worldwide develop exocrine pancreatic insufficiency, a condition that can lead to malabsorption, weight loss, and deficiencies in fat-soluble vitamins. Smoking emerged as a significant modifiable risk factor, emphasizing the need fo...
A pharmacist-led medication review improved medication quality in older adults with cancer, with 29.9% fewer patients on potentially inappropriate prescriptions and 34.2% less medication overuse. The review also recommended 337 missing vaccinations.
The new guidelines, developed by leading experts, focus on improving sepsis care by strengthening systems for diagnosis, treatment, prevention, and quality improvement. Emerging technologies, such as next-generation diagnostics and artificial intelligence, are also being explored to enhance sepsis care.
A multicenter qualitative study identified key differences in palliative care and oncology teams, affecting end-of-life patient outcomes. The findings highlight the importance of high-quality care for patients with cancer during hospice transitions.
The ACC Latin America 2026 conference will bring together experts and cardiovascular clinicians to examine emerging cardiovascular science and evidence-based strategies for improving global heart health. The conference will also recognize individuals who have earned the distinguished Fellow of the ACC (FACC) designation.
Physician David Wenzel's ethnographic fieldwork in acute hospital settings reveals how his clinical identity shapes interactions with staff. He found that introducing himself as a PhD student led to more open discussions about emotions and relational work, while wearing a student lanyard made him less visible to medical staff.
A new study found that 23% of emergency department boarding patients wait at least 4 hours before receiving inpatient-quality care, with some patients waiting 12 or 24 hours. The study highlights the importance of efficient handoffs from emergency to inpatient care, particularly for vulnerable populations.
A new book by University of Virginia Health System expert Daniel J. Cox outlines a practical alternative to medication for managing pre-diabetes and type 2 diabetes. The GEM program emphasizes smart eating, physical activity, and listening to the body to regulate blood sugar levels.
A recent study found that nearly half of the US internal medicine workforce consists of doctors born outside the United States, with significant implications for patient care in underserved communities. These foreign-born physicians provide essential care to patients from diverse backgrounds, including Black and Latino populations, and...
Non-US-born physicians, including US medical graduates and international medical graduates, account for nearly half of the US internal medicine workforce. They provide a disproportionate share of care for underserved patient populations.
In a rat model of ischemic stroke, administering rapamycin immediately after blood flow restoration reduced brain damage and improved neurological recovery. The drug's protective effects extend beyond improving circulation, suggesting additional biological mechanisms that could be targeted to improve stroke recovery.
A systematic review examined rare tumor bleeding after radiosurgery for vestibular schwannoma, identifying reported symptoms and risk factors. The study highlights the need for personalized follow-up and individualized management strategies to prevent complications.
Autonomous oxygen titration increased the proportion of time spent in normoxemia and decreased time spent in hypoxemia compared to usual care. The intervention safely increased targeted normoxemia range time in acutely ill adults.
Artificial intelligence can exacerbate or mitigate inequities in correctional health systems. Designing AI for access, inclusion, and trust is crucial for ensuring health equity among incarcerated populations. The study outlines policy and implementation considerations necessary to address these concerns.
Researchers discover soy-derived LPC70 promotes organ-specific, receptor-dependent PG signaling to counteract HS-induced cardiovascular and cognitive abnormalities. LPC70 enhances AA utilization, promoting AA-derived PG production under HSD conditions.
Researchers found perilla oil supplementation significantly prolonged platelet function and reduced inflammation in healthy smokers. The study also showed increased levels of omega-3 fatty acids and antioxidants in the body.
Researchers will examine whether online support strengthens brain development linked to emotional and mental health in prematurely born infants. The scalable intervention could transform how families receive support after discharge from the neonatal intensive care unit, bringing evidence-based support into the home.
The Pulmonary Embolism Reporting and Data Systems (PE-RADS) framework provides a simple, 0-4 grading scale for classifying acute pulmonary embolism using CT and MR angiography. The system aims to improve communication and patient care with standardized terminology and risk stratification.
A new study published in Hepatobiliary Communications reveals that standard CT scans can detect stage-specific tissue patterns predicting severe liver complications in chronic hepatitis B-related cirrhosis. Visceral fat and muscle shifts carry different warning meanings based on the patient's disease stage.
A new five-year, $2.5 million grant will support a street medicine program serving unsheltered populations in urban and rural areas of southcentral Pennsylvania. The program aims to break down healthcare barriers and provide primary care within community settings.
A recent hantavirus outbreak on a nature cruise has sparked concerns about the potential for a global pandemic. Experts warn that Ebola-like viruses pose significant threats to public health.
A new study found that hypoxic liver injury is a common complication affecting over one in five patients with severe ARDS, strongly associated with increased mortality. The study suggests that HLI may serve as a valuable prognostic marker and reflection of systemic disease severity in critically ill patients.
A mindfulness-based group medical visit program for persons with chronic low back pain showed significant improvements in pain intensity and interference compared to usual care. However, the changes did not meet the minimal clinically important difference threshold.
A national survey of 1,006 adults found that only 71% of young adults have a primary care doctor, compared to 97% of older adults. Fewer than half of young adults who do have a doctor have had a checkup in the past year.
A population-based study found no association between prenatal paracetamol exposure and risk of autism spectrum disorder or attention-deficit/hyperactivity disorder in offspring. The study suggests that positive signals from previous research may be due to familial confounding.
Researchers found a strong association between gut microbiome composition and bone health in patients with primary hyperparathyroidism. Bifidobacterium longum was identified as a key microbial driver of bone loss through immune-mediated mechanisms.
The project aims to expand University Hospitals' collaborative care model from 26 practices to all 88 practices within the UH Primary Care Institute. It will also broaden services to include screening and treatment for conditions such as bipolar disorder and post-traumatic stress disorder (PTSD).
A new AI-powered cardiopulmonary resuscitation instructor has been developed to support bystanders during out-of-hospital cardiac arrests. The study suggests that this technology could be a scalable public health intervention to save lives.
A cohort study found chronic obstructive pulmonary disease (COPD) associated with reduced life expectancy. Adults with COPD had shorter lifespans compared to those without the condition, regardless of smoking history.
Matthew Simpson, MD, receives 2026 Collaborative Fellow Scholarship from CHEST and APCCMPD to improve diversity in medical education. He aims to develop innovative approaches to teaching and mentorship.
A study found that PEG tube aspirate and vomitus display distinct color patterns, with the aspirate being yellow-green and the vomitus dark brown. This contrast can serve as a diagnostic clue for gastric outlet obstruction in resource-limited settings.
The ERASur clinical trial is investigating whether total ablative therapy can improve overall survival in patients with newly diagnosed, limited metastatic colorectal cancer. The study has reached one-third patient accrual milestone, signaling strong momentum.
This article provides an overview of anxiety disorders, including their symptoms, diagnosis, and treatment options. The study found that anxiety disorders can be effectively managed with a combination of therapy and medication.
The ASPIRE trial aims to enroll 1,200 participants with advanced prostate cancer and assess the impact of chemotherapy on overall survival and disease progression. Genetic profiling is included to identify patients who benefit most from intensified treatment.
The American Medical Association (AMA) has developed guidelines for treating anxiety disorders in adults in primary care settings. Behavioral therapy, including cognitive-behavioral therapy (CBT), and medication, such as selective serotonin reuptake inhibitors (SSRIs), are recommended treatments.
Unsecure firearm storage is common among older adults with subjective cognitive decline, despite clinical guidance recommending secure storage for those with cognitive symptoms. The study highlights the need for improved household practices and access to fire safety education.
A nationally representative study found nearly 1 in 10 U.S. adults with heavy drinking and obesity conditions, highlighting the need for preventive efforts in younger and middle-aged adults without insurance or Medicaid coverage to curb rising rates of alcohol-associated liver disease deaths.
A $35 monthly insulin out-of-pocket cap is associated with significantly lower insulin costs, increased access to insulin, and decreased blood glucose levels among Medicare beneficiaries. This finding suggests that federal cost-sharing policies could improve access to essential medications in diabetes.
Dr. Cudjoe's research examines the influence of social connection on health and developing interventions to address social isolation in older adults. He is a recipient of several awards, including the National Institute on Aging GEMSSTAR award and the Robert Wood Johnson Foundation Amos award.
A study found that high screen time and low physical activity are strongly linked with cardiovascular risk among young adults. Screen time was independently associated with markers of cardiovascular risk, even after accounting for differences in daily physical activity.
A study analyzing monthly temperatures and cardiovascular deaths found that cold weather accounted for about 6.3% of all cardiovascular deaths, resulting in 800,000 excess deaths over two decades. The research highlights the need for communities to prepare for climate change's impact on extreme cold.
Continuing GLP-1/GIP agonists before upper endoscopy increased clinically significant residual gastric volume, but did not elevate adverse event risk. Clear liquids the day prior to the procedure may mitigate this risk.
A new clinical trial will investigate whether adding the oral medication vorasidenib to standard chemotherapy improves progression-free survival for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma. The study aims to recruit 400 individuals with this type of brain cancer and evaluate the safety and side-effect profile of the...
A $3.4 million NIH grant will fund a semi-automated feedback system to support people tracking diet, exercise, and weight in weight-management programs. The system aims to provide personalized feedback to increase tracking and weight loss success.
A systematic review and meta-analysis found GLP-1 RAs produce significant weight loss across various subpopulations, including women who show improved outcomes compared to men. These findings have implications for clinical decision-making.
The study found that increased community disadvantage leads to fewer options for receiving hemodialysis and more likelihood of living without nearby dialysis facilities. Patients with end-stage kidney disease in these areas have limited access to essential care services.
A group of nerve cells in the brainstem has been identified as a stabilizing system for blood pressure, preventing fluctuations between daily activities. The study suggests that loss or dysfunction of these cells can lead to unstable blood pressure and is associated with conditions such as multiple system atrophy.
A population-based study reveals that rotator cuff abnormalities are common after age 40 and often represent normal age-related changes. The findings challenge the clinical value of routine imaging for atraumatic shoulder pain, questioning the need for regular scans in this demographic.
A recent study published in JAMA Internal Medicine found that oral semaglutide has a potential benefit in reducing heart failure events among people with type 2 diabetes and existing heart failure. The data support the use of oral semaglutide as a treatment option for these patients.
The American College of Chest Physicians' CHEST Critical Care journal has been added to the Web of Science Core Collection through the Emerging Sources Citation Index. This indexing marks a significant milestone for the journal, increasing access to high-quality research and supporting its commitment to advancing critical care medicine.
The study examines the characterization of the international-born health care workforce in rural US communities. It highlights the Conrad 30 waiver program, which enabled thousands of J-1 visa holders to remain in the US, caring for approximately 44 million patients, and H1-B visas as additional vehicles for immigrant clinicians.
The Ann Arbor Guide provides two algorithms for triaging adults with suspected UTIs, one for non-pregnant women and the other for men. It also emphasizes the importance of accurate testing and treatment to prevent overuse of antibiotics and antibiotic resistance.
A comparative effectiveness study found that SGLT2 inhibitors were associated with a lower risk of chronic kidney disease and acute kidney injury compared to GLP-1 receptor agonists. These findings suggest that SGLT2 inhibitor treatment may be an effective strategy for preventing kidney disease in individuals with type 2 diabetes.
Researchers identify circulating extracellular vesicles produced in diseased kidneys as the culprit behind toxicity in the heart. The discovery could lead to the development of a blood test to identify patients at high risk for serious heart problems and novel treatments to prevent and treat heart failure.
A recent University of Michigan study analyzed over 60 million Medicare participants and found that total visits remained stable or declined slightly through June 2024. Despite widespread adoption of telehealth, overall healthcare visits stayed steady or decreased, contradicting predictions of increased utilization.
Research finds cancer cachexia-related immune cells impair T-cell negative selection, leading to irAEs. This study establishes a critical mechanism connecting cancer cachexia and irAEs, opening new avenues for targeted interventions.
A recent study published in JAMA Internal Medicine found that a significant majority of Americans will experience cost burdens due to healthcare expenses throughout their lives. The study suggests that policies aiming to reduce out-of-pocket costs could potentially improve the well-being of individuals in the US.
The study will select the exact phage that is appropriate for each patient's bacteria, and aims to reduce antibiotic use and healthcare costs. Bacteriophages have been shown to be effective against resistant bacteria causing urinary tract infections.