Articles tagged with Phosphates
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A team of researchers at the University of Leicester has made significant progress in understanding the role of inositol phosphate molecules in regulating gene expression. By developing a novel peptide-based inhibitor, they have gained insights into how enzymes are activated by these small molecules, paving the way for more specific an...
In a groundbreaking study, researchers found that plants deliberately choose which fungal partners to provide with more nutrients, effectively forcing the less cooperative partner to supply more phosphates. This market-based process allows for optimal resource allocation and increased plant productivity.
Researchers have discovered a chemical method to immobilize uranium in contaminated groundwater, which could lead to more precise water remediation efforts. The technique involves adding specific amounts of phosphate to form a calcium phosphate barrier that traps uranium, rendering it inert.
Researchers at the University of Delaware have developed a method to break down glyphosate, a common commercial herbicide, using manganese oxide minerals. The study found that the mineral can degrade glyphosate and AMPA, a major byproduct, within hours, providing a potential solution to environmental concerns about these compounds.
Researchers discovered that thale cress plant tolerates fungus when it needs help obtaining phosphate, rejecting it otherwise. The plant controls interaction through its immune system linked to a sensor for phosphate availability.
A $1.2 million DOE grant will support the development of biosensors to track phosphate movement in real-time, enabling more efficient use of symbiotic relationships between plants and AM fungi. This technology has broad applications beyond biofuels, benefiting economically important crops worldwide.
Researchers have identified biomarkers and potential therapeutic approaches for pulmonary alveolar microlithiasis (PAM), a rare lung disease. A low-phosphate diet and EDTA treatment were found to prevent stone development and reverse lung calcification in animal models.
Researchers have discovered how bacteria convert phosphonate compounds into phosphate, using a complex of fourteen proteins. This mechanism could be used to develop techniques for removing pesticide residues from drinking water and understanding the greenhouse effect.
A new study by Houston Methodist researchers finds that artificially added phosphates in dairy and cereal products cause bigger spikes in blood phosphorus levels than natural phosphates. This can lead to increased kidney function problems and heart damage, especially for people with healthy kidneys.
A new Northwestern Medicine research center will investigate the potential heart damage caused by excess dietary phosphate, particularly in African Americans. The goal is to find new ways to prevent and treat heart failure and build evidence for regulating phosphate in the food supply.
Researchers developed a new method to map critical chemical tags on proteins, enabling better understanding of protein formation and function. The technique allows pinpointing phosphates' location and studying unstable amino acids like histidine.
A new study reveals a complex marine phosphorus cycle with a hidden role for microbial communities. Microbes transform phosphorus into phosphonates at varying rates depending on depth, shedding light on the ocean's ability to absorb atmospheric carbon dioxide.
A study by Woods Hole Oceanographic Institution and Columbia University reveals a more complex marine phosphorus cycle than previously thought, with microbes playing a key role in using and breaking down forms of the essential element. In the process, about five percent of phosphate is converted to phosphonates in shallow water samples.
New research found that mycorrhizal fungus triggers additional root growth in rice crops, allowing them to absorb more nutrients. The fungus also enmeshes itself within plant cells, providing a direct mineral boost.
A new study found that high phosphate levels cause a stress signal inside blood vessel cells, leading to the release of microparticles that promote blood clot formation. This process is a common cause of injury and death, particularly in patients with kidney disease who lose the ability to excrete excess phosphate.
Phosphorylation and methylation of desmoplakin regulate its interaction with the cytoskeleton, affecting cell-to-cell connections. The study reveals a regulatory mechanism that contributes to skin and heart diseases.
A new study published in Proceedings of the National Academy of Sciences has found microscopic spheres of calcium phosphate in eyes with age-related macular degeneration (AMD), a leading cause of blindness. The discovery opens up new avenues for diagnosis and treatment, potentially allowing early detection and prevention of the disease.
Researchers at the University of Alberta have explained how a key protein in the heart changes in heart failure, shedding light on the molecular mechanisms behind this complex condition. By studying troponin I, they discovered that increased calcium sensitivity actually helps trigger contraction, despite slower relaxation.
Researchers estimate mercury levels in global ocean, separating natural and human sources for the first time. The study found that ocean waters shallower than 100m have tripled in mercury concentration since the Industrial Revolution.
Scientists used X-ray imaging and chemical fingerprinting to analyze lithium iron phosphate battery material under operating conditions. The results show that fast charging inhibits the material's performance due to inhomogeneous phase transformation, while slower charging yields higher capacity.
Researchers at MIT have discovered a 'random solid solution' that affects how ions move through the material, explaining the unexpectedly high power and long cycle life of lithium-ion batteries. The study provides new insights into the dynamic processes within electrode materials.
Excessive phosphate consumption stimulates the production of FGF23, leading to negative effects on the cardiovascular system, including high blood pressure and vascular calcification. The study provides new insights into the connection between renal disease, FGF23 levels, and cardiovascular disease.
Researchers from the University of Granada have patented a technique that allows for real-time and non-invasive measurement of phosphate ions inside osteoblasts, precursors to bone cells. This breakthrough could lead to the development of new drugs against osteoporosis.
The Silver Banksia plant genus has developed a strategy to cope with phosphorus scarcity by reducing ribosomal RNA in their cells, saving phosphorus and water. By optimizing phosphate use, Proteaceae plants outperform Arabidopsis thaliana in photosynthetic efficiency.
Researchers at Johns Hopkins University have discovered that reversible chemical tags attached to the PTEN protein can regulate its activity. When these phosphate groups are bound, PTEN becomes inactive, suppressing cell division and migration. This finding may lead to new options for drug design to keep PTEN working.
A study found that a phosphate-binding drug did not reduce cardiovascular measures in patients with early chronic kidney disease, suggesting dietary restriction may be the best way to mitigate phosphate's negative effects on the heart. Higher blood phosphate levels increase the risk of dying from heart-related causes.
Scientists at McGill University and the Federal University of Sao Paulo have identified osteopontin as a key player in X-linked hypophosphatemia (XLH), a rare bone disease characterized by soft bones and tooth abnormalities. This discovery may lead to the development of an enzyme-replacement therapy to treat XLH patients.
The project aims to optimise the process of reducing lead in tap water by identifying the least soluble minerals. Researchers will investigate water from various sources and work on-site at Yorkshire Water treatment plants.
A new antibiotic, tedizolid phosphate, has been shown to be effective in treating skin infections with a shorter course than traditional treatments. The study found that the new antibiotic was noninferior to linezolid in both early and sustained clinical responses.
Researchers at Ruhr-University Bochum found an overactive CaM kinase II enzyme in failing hearts, which relaxes muscle cells by phosphorylating the giant protein titin. This may lead to a new starting point for treating heart failure.
Researchers discovered that bacteria in arsenic-rich environments developed a protein, PBP, with extreme selectivity for phosphate over arsenate. The unique bond between the protein and arsenate molecule led to repulsion and prevented its entry into the cell.
Researchers at Ruhr-Universität Bochum use infrared spectroscopy and computer simulations to study the Ras protein's role in cell growth. They found that Ras accelerates the cleavage of GTP by putting a phosphate chain under tension, which slows down cell growth.
Researchers at Simon Fraser University have identified a key protein kinase, Hipk, that regulates the growth-promoting protein Yorkie, which is often found in human tumors. The study suggests that inhibiting Hipk activity may prevent tumor growth and cancer.
A recent study has questioned the safety and effectiveness of commonly prescribed kidney disease drugs, which may cause unexpected harm to blood vessels. The study found that these drugs did not substantially reduce serum phosphorus levels and may be associated with cardiovascular problems in patients with chronic kidney disease.
A study by the University of Illinois discovered that supplementing pig feed with varying levels of phytase increases phosphorus digestibility in different ingredients. The research found that enzymes can unlock bound phosphorus, reducing environmental impact and costs for producers.
A new protein called Lem4 has been discovered to direct a crucial step in cell division by preventing the addition of phosphate tags to BAF while promoting their removal. This process is essential for cellular growth and division, and its regulation may be key to understanding various cellular processes.
Researchers have increased knowledge of the O-GlcNAc regulatory system, a little-known mechanism that regulates proteins in cells. The study found hundreds of proteins modified by O-GlcNAc, which suggests a larger coordination between the O-GlcNAc and phosphate-based regulatory systems.
Researchers at Queen's University Belfast have developed a biotechnological route to remove and recycle phosphate from wastewater. The team has discovered a physiological 'shock' treatment that significantly increases microbial uptake of phosphorus and its accumulation inside cells.
A new study reveals that cells employ a dual-pump mechanism to maintain optimal nutrient levels, allowing for efficient preparation for starvation and rapid recovery afterwards. This regulatory system enables the cell to deal with fluctuations in nutrient supply, offering crucial survival advantages.
A new study by Washington University in St. Louis found that joining old lead pipes with new copper lines using brass fittings increases the amount of lead released into drinking water supplies due to galvanic corrosion. This can make the problem worse for safety-minded, lead-pipe-removal programs at water utilities across the country.
Chronic kidney disease patients with high blood phosphate levels may be at risk of progressing to kidney failure faster. Lowering phosphate levels could help optimize the effectiveness of important kidney medications like ramipril.
Researchers found that European alpine soils generally retain similar amounts of phosphate, ranging from 9-145 mmol kg-1, with aluminum oxide concentration being the key factor. Acidified soils retain more phosphate than non-acidified ones.
Mycorrhizal fungi can increase plant growth with less phosphate fertilizer, solving a pressing challenge for global food production. Researchers have discovered that using mycorrhizal fungus gel can produce the same yield as traditional farming with up to half less phosphate fertilizer.
A new study reveals that glycogen synthase mistakenly incorporates phosphate molecules into glycogen, leading to the accumulation of 'wrecked' glucose in neurons and the formation of deposits called Lafora bodies. This discovery may lead to a viable therapeutic intervention for Lafora disease, which has no current effective treatment.
Scientists at Indiana University School of Medicine have identified the source of excessive phosphate buildup in glycogen, a chain-like molecule used to store energy. This finding sheds light on a possible route to treatment for Lafora disease, a rare and deadly condition caused by genetic mutation.
New phosphate-free automatic dishwashing detergents are being developed to combat water pollution, but they may not be as effective as previously thought. Researchers are working on alternative formulas that can clean dishes without contributing to environmental harm.
Researchers fill in a missing gap in the mechanism of how brassinosteroids cause plant genes to be expressed, with implications for agricultural science and evolutionary research. Protein phosphatase 2A (PP2A) is identified as the key component of the signaling pathway.
A study by Brigham and Women's Hospital found that restricting dietary phosphate does not improve survival rates among hemodialysis patients. In fact, patients with more liberal phosphate restrictions were 27% less likely to die than those on restrictive diets.
A study found that low socioeconomic status is associated with higher serum phosphate levels in patients with chronic kidney disease, regardless of race. This suggests that limited access to healthy food choices contributes to the racial disparity in kidney disease progression.
Toxic blue-green algae, like Aphanizomenon ovalisporum, dominate freshwater ecosystems by inducing phosphate-limitation responses in other microorganisms. This 'enslavement' mechanism enables the algae to gain a nutrient advantage and proliferate dangerously in freshwater bodies.
Researchers at PNNL developed a simple one-step method to create high-capacity lithium manganese phosphate electrodes using paraffin wax and soap. The new process enables the exploration of cheaper alternatives to current lithium-ion-metal oxide batteries, with potential applications in electric vehicles and consumer electronics.
Researchers create nanoparticle that effectively delivers genetic material into cells, outperforming existing methods. The device, a vector, is between 2 ½ and 10 times more effective than other experimental materials, according to the research.
Researchers found that manipulating fungal genetics increases rice growth by five-fold, addressing global phosphate reserves critically low issues. The breakthrough exploits the fungus's genetic variation and segregation processes without introducing new genes.
New research shows that high phosphate levels in sodas and processed foods can accelerate the aging process in mice, contributing to age-associated complications like chronic kidney disease. Humans need a balanced diet, and avoiding phosphate toxicity may be important for longevity.
Research at Emory University School of Medicine found that high phosphate diet promotes tumor formation and growth in skin cancer, while restricting phosphate may prevent cancer. The study suggests that altered levels of phosphate could tip the balance of chemical reactions influencing cancer development.
Researchers at Johns Hopkins Medicine discovered that sugar-based protein modification called O-GlcNAcylation regulates cell division. Disrupting this process can lead to polyploidy, a condition exhibited by many cancer cells. The findings have implications for new treatments for diseases like cancer.
Researchers identified a phosphatase enzyme that removes phosphate from LHCII proteins, allowing for the balance of light energy between two photosystems. This discovery has practical implications for improving plant growth and potentially reducing energy bills.
A study published in World Journal of Gastroenterology found that oral sodium phosphate (OSP) laxatives can induce hyperphosphatemia in low-risk patients, particularly those with lower weights. The research suggests that preoperative evaluation and adjusting OSP doses according to weight may help prevent this condition.
A University of Iowa study reveals a critical link in the sugar chain of an important muscle protein, providing insights into congenital muscular dystrophies and cancer progression. The discovery may lead to new therapies for treating these conditions.
Researchers at Penn State have developed a new type of glass that blocks ultraviolet light and has increased radiation damage resistance. The cerium-containing phosphate glasses can be used in windows, sunglasses, and solar cells.