Articles tagged with Integrative Neuroscience
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study from the Stowers Institute has identified a mechanism that makes fleeting moments unforgettable, revealing a critical step in forming long-lasting memories. The research discovered a specific type of chaperone protein that allows proteins to change shape and form functional amyloids that house long-term memory.
Researchers at Rockefeller University discovered that fruit flies use a two-neuron system to calculate wind direction, leveraging double-duty signaling mechanisms. This finding redefines our understanding of how neurons compute direction and navigate their environment.
A study by Dr. Esther Sternberg highlights the importance of social engagement, intellectual stimulation, purposeful activity, humor, and spiritual exploration in achieving exceptional cognitive and social functioning in advanced age. Dr. Reichlin's example challenges conventional assumptions about aging trajectories.
Bioengineering researchers at Harvard John A. Paulson School of Engineering and Applied Sciences developed a soft, thin, stretchable bioelectronic device that can be implanted into a tadpole embryo's neural plate, recording electrical activity from single brain cells with millisecond precision.
The Greater Mouse-Tailed Bat uses its long tail as a dynamic sensing tool to avoid obstacles and orient itself in complex environments, especially when vision and echolocation are limited. The study found that the bats' ability to navigate decreased significantly when their tail was numbed.
The Open Brain Institute launches a groundbreaking platform to simulate and study digital brains, empowering researchers to explore brain complexity and diseases. With its virtual neuroscience laboratories, the OBI enables global collaboration and access to cutting-edge virtual labs.
Researchers used fMRI data to uncover how the hippocampus coordinates memory processes by analyzing neural activity patterns. The study found that participants remembered scenes with lower novelty more accurately and that the hippocampus integrates diverse forms of novel information.
Researchers at Cold Spring Harbor Laboratory have devised a potential solution to the paradox of animal innate abilities using artificial intelligence. The genomic bottleneck algorithm allows for compression levels unseen in AI, enabling faster runtimes and potentially leading to more evolved AI systems.
The team plans to use a multidisciplinary approach to characterize brain mechanisms that underlie resiliency, aiming to develop better therapies and address public need. Most individuals exposed to high levels of stress and trauma are able to avoid serious mental illness, suggesting that biological resilience is prevalent.
Researchers identified hundreds of brain proteins associated with inter-individual differences in functional connectivity and structural covariation. The proteins were enriched for those involved in synapses, energy metabolism, and RNA processing, providing insights into the mechanistic basis of human cognition and behavior.
Researchers develop transcranial ultrasound stimulation (TUS) as a non-invasive therapy for brain-related issues, with potential for personalized treatments. A 'search and rescue tool' for the brain, TUS enables precise targeting of specific areas before treatment.
Researchers at Brigham and Women's Hospital have identified a specific brain circuit that may protect against post-traumatic stress disorder (PTSD) in veterans with traumatic brain injury. The study suggests using neurostimulation therapies on this circuit could treat PTSD, offering a new potential non-invasive treatment option.
Researchers used fMRI to observe brain activity in participants exposed to varying levels of pain stimuli, manipulating their expectations about the level of pain. The study found that higher-level networks integrated pain-related signals into the experience of pain by adding preserved expectation and stimulus information together.
Researchers developed a shape-morphing cortex-adhesive sensor to monitor brain activity during tFUS stimulation, enabling real-time adjustments and suppressing seizures. The innovative device overcomes challenges in existing cortex-interfacing devices, providing stable and accurate monitoring.
A new study reveals that a third of glioma cells, a type of brain tumor, fire electrical impulses. These hybrid cells combine features of neurons and glia, challenging the long-held notion that only neurons generate electric signals in the brain.
A roundtable discussion explores the integration of positive psychology and autism, highlighting its potential to amplify strengths and improve interpersonal dynamics. The study suggests that appreciating character strengths can have a significant impact on daily life.
Researchers discovered that propofol, a commonly used anesthesia drug, induces unconsciousness by causing the brain to become increasingly unstable. This instability leads to chaotic brain activity, resulting in loss of consciousness. The study's findings could help develop better tools for monitoring patients during general anesthesia.
A global task force of scientists created an integrative framework to study emotions and moods, situating experiences within a single theoretical framework. This framework helps understand mental disorders like depression and anxiety, as well as decision-making and human behavior.
Researchers found a correlation between body temperature and depression symptom severity in a large international study. Participants with higher depression scores had higher body temperatures, suggesting that cooling the body may be a novel treatment approach for depression.
Researchers developed an ingestible capsule to measure vital signs from within the GI tract, detecting sleep apnea episodes and breathing rate depression. The device shows promise for early detection of respiratory changes, including those caused by opioids or asthma/COPD.
Researchers found that hierarchical cortical organization is impaired in people with schizophrenia, leading to disruptions in processing stimuli from the external world. This disruption affects secondary processing of sensorimotor-visual gradients, explaining behavioral and clinical symptoms of the disease.
The Human Brain Project has driven outstanding advances in brain research and medicine, producing over 3000 academic publications and 160 digital tools. The EBRAINS infrastructure will remain accessible to the scientific community after the project's end.
The Human Brain Project has achieved major breakthroughs in understanding the complex structure and function of the brain, enabling novel medical and technological applications. The project's digital atlas and personalized virtual models have provided unprecedented insights into brain conditions such as epilepsy and Parkinson's disease.
Neurologist Soma Sengupta introduces the concept of integrative neuro-oncology, combining conventional treatments with alternative therapies to enhance patient well-being. Her approach prioritizes the unique needs of brain tumor patients and their caregivers, promoting a holistic understanding of medicine.
A community-engaged approach to research prioritizes the concerns of participating communities, leading to a better reflection of community needs and issues. By incorporating CBPR, researchers can minimize biases and increase public trust in science.
The Human Brain Project Summit 2023 will highlight the scientific achievements of the project at the interface of neuroscience and technology. Researchers will present cutting-edge research on European advances in neuroscience and applications in medicine and brain-derived technologies.
Researchers discovered a neural system for self-localization in larval zebrafish using whole-brain functional imaging. The multiregional hindbrain circuit integrates visual information to form a memory of past displacements, correcting for accumulated displacements over many seconds.
Researchers discovered that humans automatically integrate extralinguistic information into grammatical processing, improving communication. The study used EEG data from 37 native Russian speakers, finding both linguistic and extralinguistic features processed simultaneously.
The Human Brain Project (HBP) has brought together neuroscientists from different disciplines to work collaboratively on common goals. The HBP researchers outline their scientific approach and illustrate the potential of EBRAINS infrastructure for neuroscience research.
Researchers reexamined hundreds of experiments on neural activity and consciousness, finding that experiment parameters determine results. The study used artificial intelligence to predict which theory would be supported by each experiment with 80% success.
Researchers at MIT and University of London found that collective electric fields produced by neurons provide a stable and consistent signal of information in working memory. This allows the brain to function even if individual neurons die or change.
The Human Brain Project's Scientific Conference presents abundant scientific achievements in neuroscience, brain medicine, and technology. Renowned experts discuss past, present, and future of brain research, highlighting the role of HBP in driving innovation.
An international study found that the protein PRMT6 ensures transport along axons, and its loss leads to neural impairment. Increasing PRMT6 expression may restore huntingtin function and improve neural health in patients with Huntington's disease.
A recent study used neuroimaging and AI to uncover the brain's network for sentence understanding, finding activity in multiple regions including anterior and posterior temporal lobes. The researchers also predict patterns of brain activity using an AI model trained on Facebook data.
Researchers are developing personalized, democratized technological solutions to transform vision rehabilitation for children and adults. Digital haptics and sound technology are being integrated to enable the visually impaired to learn about new objects and spaces instantly.
A special issue of Current Opinions in Psychology maps the state of mindfulness research, exploring its historical foundations, clinical applications, and social implications. The study reveals that mindfulness can be learned and applied uniquely across different contexts, with mobile apps emerging as a promising platform for deliverin...
Researchers found three distinct brain circuits involved in making good and bad decisions, with the third circuit storing memories of past choices. The study may help explain addiction and inform novel treatments for substance abuse.
A new conceptual framework proposes examining exercise effects on brain connectivity, structure, and molecular mechanisms in multiple sclerosis. This systematic approach may lead to new strategies for rehabilitative care and treatment.
Researchers developed 4-D goggles that allow wearers to feel a looming object on screen, such as an approaching spacecraft. The device synchronizes with entertainment content to deliver immersive multisensory effects near the face and enhance sense of presence.
Scientists propose a computational model explaining multisensory integration in humans, utilizing a Multisensory Correlation Detector. The brain detects similarity across visual and auditory signals to integrate stimuli, opening new clinical perspectives for neurological syndromes like Autism Spectrum Disorder and Dyslexia.
Experts in neuroscience education call for reinvestment in graduate training to prepare students for the challenges of brain science and disease. The paper proposes creating two types of training programs: those that extend traditional neuroscience training and those that engage students with backgrounds in other disciplines.
A new common format, Neurodata Without Borders (NWB): Neurophysiology, enables free and open exchange of complex brain information. The format allows researchers to capture and share data generated by optical and electrical neurophysiology methods.
Attention plays a critical role in structuring the internal world, prioritizing relevant thoughts and emotions for goal-oriented processing. The integrated theory proposes that attention is a cascade of effects beginning with stimulus detection, suppressing competing stimuli, and resetting upon completion.
A high-fat diet changes the populations of bacteria residing in the gut, altering signaling to the brain and leading to overeating. The study found that this shift can cause inflammation in brain regions responsible for feeding behavior, resulting in gut-brain miscommunication and obesity.
The special issue emphasizes the importance of combining intervention strategies focusing on both nutrition and early learning to support healthy development. The research reveals that 200 million children under five are not reaching their developmental potential due to poverty, nutritional deficiencies, and lack of responsive caregiving.
Extensive musical training affects brain structure and function, particularly when started before age 7. Research suggests that musical improvisation can rewire the brain, fostering plasticity and enhancing creativity, cognition, and learning.
Jonathan Wisco, associate professor at Brigham Young University and UCLA, receives the Basmajian Award for his outstanding contributions to teaching and research in anatomy. He has increased teaching responsibilities and established a laboratory to support translational anatomy research.
Humans exploit correlation between signal temporal structures to decide which signals to combine. Multisensory integration occurs when auditory and visual streams have similar temporal patterns, resulting in improved precision and accuracy. This research highlights a key organizational principle for multisensory perceptual grouping.
A new open digital brain atlasing framework, combining Waxholm Space and Digital Atlasing Infrastructure, facilitates the integration of genetic, anatomical, and functional imaging studies. This framework is expected to catalyze both basic and medical neuroscience research by linking genetic studies with large-scale brain structure and...
Researchers at UC Berkeley found that dominant hyenas produce steady, confident-sounding giggles, while subordinate ones have more variable calls. The study's findings suggest that the frequency analysis of these calls can reveal an animal's social stature and age.
Researchers aim to understand how sensory integration goes awry in autism and its implications for clinical management. They will compare multisensory integration in subjects with autism to healthy control subjects using high-density electrical recordings.