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Flexible DNA transforms protein crystallization

Northwestern University chemists have developed a new approach that replaces traditional trial-and-error methods with intentional design using flexible DNA strands. The strategy enables precise control over protein connections, creating soft, flexible crystals with high structural order. This breakthrough simplifies one of structural b...

SourceNorthwestern University·JournalScience Advances·DateJul 29, 2026

Wild chimps filmed sharing ‘boozy’ fruit

Researchers at the University of Exeter have observed wild chimpanzees consuming and sharing fermented African breadfruit containing ethanol, raising questions about the potential benefits of alcohol consumption in primates. The study suggests that chimps may be seeking out alcohol for social bonding and relaxation, similar to humans.

SourceUniversity of Exeter·JournalCurrent Biology·DateApr 21, 2025

UV light activation of peracetic acid: new insights into radical generation based on excited states

Researchers developed an in-situ EPR setup to accurately identify radicals generated by PAA activation under different UV wavelengths, revealing distinct radical generation pathways. The study provides new insights into the mechanisms of radical formation and transformation using density functional theory calculations.

SourceScience China Press·JournalScience Bulletin·TypeExperimental study·DateApr 9, 2025

What social rejection teaches your brain

A USC study reveals that forming social ties relies on learning from positive outcomes, such as rewards, and tracking relational value. The findings help explain why we are drawn to certain people and how we navigate relationships, with implications for mental health and social behavior.

SourceUniversity of Southern California·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateDec 10, 2024

Advancing the synthesis of two-dimensional gold monolayers

Scientists at Lund University and Hokkaido University have successfully synthesized 2D gold monolayers with remarkable thermal stability and potential catalytic utility. The team used a novel bottom-up approach combined with high-performance computations to create macroscopically large gold monolayers with unique nanostructured patterns.

SourceHokkaido University·JournalNature Communications·TypeExperimental study·DateDec 10, 2024

Buffalo besties: Feral female buffalo build friendships based on similar personality traits

A new study has discovered that close spatial proximity serves as an indicator of friendship in feral female buffalo, with individual personalities playing a key role. The research found that buffalo with similar social tension, vigilance, and general dominance traits tended to spend more time together.

UBCO researchers engineer DNA to mimic biological catch bonds

Researchers have developed an artificial adhesion system that closely mimics natural biological interactions, enabling precise control over its strength under varying forces. The innovative 'fish-hook' bond has vast potential in materials science and medicine, inspiring responsive materials and force-sensitive drug delivery systems.

SourceUniversity of British Columbia Okanagan campus·JournalNature Communications·TypeExperimental study·DateDec 2, 2024

First successful synthesis of naphthocyclinones since their discovery fifty years ago

Researchers at Institute of Science Tokyo develop an innovative strategy to produce β- and γ-naphthocyclinones, challenging compounds that have potential for medical and biological applications. They successfully synthesize the molecules using a retrosynthetic analysis approach, achieving yields of over 70%.

SourceInstitute of Science Tokyo·JournalAngewandte Chemie International Edition·TypeExperimental study·DateNov 18, 2024

A holy grail found for catalytic alkane activation

Hokkaido University researchers have developed a novel method to activate alkanes, making it easier to convert these building blocks into valuable compounds. The new technique utilizes confined chiral Brønsted acids, improving efficiency and selectivity in producing desired products.

SourceHokkaido University·JournalScience·TypeExperimental study·DateOct 10, 2024

Fluorescent molecules to illuminate life: simplified synthesis with formaldehyde

A research team has developed a simplified synthesis method for organic fluorophores using formaldehyde, reducing molecular size and increasing atomic efficiency. The new technique can also be applied to in vivo environments, showing promise for life sciences research and diagnostics applications.

SourcePohang University of Science & Technology (POSTECH)·JournalAngewandte Chemie International Edition·DateSep 30, 2024

Fast folding for synthetic peptides and microproteins

Researchers at Xi'an Jiaotong-Liverpool University developed a new method that enables the efficient production of cysteine-rich peptides and microproteins in their naturally folded 3D structure. The approach uses organic solvents to mimic nature's oxidative folding process, resulting in speeds of over 100,000 times faster than aqueous...

SourceXi'an Jiaotong-Liverpool University·JournalAngewandte Chemie·TypeExperimental study·DateMar 21, 2024

Light stimulates a new twist for synthetic chemistry

Researchers at Hokkaido University have developed a new category of molecules that can undergo internal rotation on interaction with light, opening possibilities for photochemical switching functions and bioactive molecules. This breakthrough could lead to precisely targeted applications in biological systems and eventual therapeutic p...

SourceHokkaido University·JournalNature Chemistry·TypeExperimental study·DateFeb 28, 2024

The rock that creates clouds

Researchers at TU Wien discovered that feldspar's unique surface geometry provides the perfect anchoring point for water molecules, enabling efficient cloud formation. The hydroxyl layer formed on the feldspar surface allows water molecules to stick and freeze, forming clouds.

SourceVienna University of Technology·JournalThe Journal of Physical Chemistry Letters·DateJan 9, 2024

Carbon atoms coming together in space

Researchers at Hokkaido University have discovered a mechanism for carbon atoms to come together on the surface of interstellar ice grains, producing complex organic molecules. This process occurs at temperatures above 30 Kelvin and may have played a role in the origin of life on Earth.

SourceHokkaido University·JournalNature Astronomy·TypeExperimental study·DateSep 14, 2023

Adult friendships can triumph over childhood trauma, even in baboons

A new study of nearly 200 baboons in southern Kenya found that adversity early in life can take years off their lifespan, but strong social bonds with other baboons in adulthood can help get them back. Baboons who formed stronger social connections added 2.2 years to their lives, no matter what they had faced when they were younger.

SourceDuke University·JournalScience Advances·TypeData/statistical analysis·DateMay 17, 2023

Oncotarget | Oncogenic driver FGFR3-TACC3 requires 5 coiled-coil heptads for activation and disulfide bonds for stability

Researchers identify the minimum contribution of TACC3 for FGFR3-TACC3 fusion protein activation, revealing a novel target for treating FGFR translocation-driven cancers. The study shows that clinically identified FGFR3-TACC3 fusion proteins differ in biological activity depending on specific breakpoints.

SourceImpact Journals LLC·JournalOncotarget·TypeExperimental study·DateFeb 23, 2023