Articles tagged with Academic Journals
Recent research suggests that senescence often limits stem cell activity in normal tissues but can also promote tumor progression in cancer. Understanding the dynamic interplay between these two biological processes is crucial for developing safer regenerative therapies and more effective cancer treatments.
The journal addresses ethical challenges, best practices, and scientific integrity issues through metascience and evidence-based research standards. Emerging technologies like AI are transforming how researchers conduct, communicate, and disseminate their work.
Researchers found that a 12-week lifestyle program combining exercise guidance, dietary counseling, and daily yogurt consumption significantly slowed DunedinPACE, an epigenetic measure of biological aging. The intervention resulted in a modest but statistically significant slowing of the pace of aging, corresponding to a 2.2% reduction.
Researchers found frequent silencing of TRAIL-R2 in breast tumors through promoter hypermethylation, associated with invasive ductal carcinoma and advanced tumor stage. Lower TRAIL-R2 expression was linked to more aggressive disease and reduced overall survival.
JMIR Publications and Jisc have expanded their Flat-Fee Unlimited Open Access Partnership, making APCs free for researchers affiliated with participating institutions. The agreement allows researchers to prioritize open access publishing without financial burdens.
Combined hepatocellular-cholangiocarcinoma is a rare and aggressive form of primary liver cancer that poses significant diagnostic and therapeutic challenges. The absence of standardized treatment guidelines limits effective management, emphasizing the need for thorough pathological evaluation and multidisciplinary management.
JMIR Publications has extended its agreement with Eindhoven University of Technology for two years, providing researchers with unlimited APC-free publishing in all JMIR's Gold Open Access journals. The partnership eliminates individual Article Processing Charges (APCs) and ensures equity for TU/e researchers.
A new study reveals that p38MAP kinase plays a central role in regulating senescence-related changes in human muscle cells. The researchers developed a human cell-based model to investigate how senescence develops in skeletal muscle cells and identified a signaling pathway that appears to drive aging in mature muscle fibers.
The Indonesian Academy of Sciences has launched an open access journal, Journal of the Indonesian Academy of Sciences, with Taylor & Francis to bridge research and policy. The multidisciplinary journal features original research, opinion pieces, and a policy forum, making it an authoritative source for policymakers and practitioners.
JMIR Publications' journals have achieved strong rankings, with 12 in the first quartile and 6 in the 90th percentile or higher. The journal of Medical Internet Research has an all-time high Journal Impact Factor of 8.2.
The Journal of Research on Research aims to support evidence-informed change in research systems through a unique dual role as both a publisher and researcher. It will occupy a dual role: publish and conduct research on research, providing access to data on publishing processes across its portfolio.
JMIR Publications has partnered with MetaROR to advance open science, elevate peer review quality, and recognize reviewers' contributions. The partnership integrates MetaROR's publish-review-curate platform with JMIRx overlay journals.
The Global Conference on Gerophysics brought together researchers from various disciplines to develop predictive models of aging. Key findings include the application of physical principles, such as thermodynamics and network theory, to biological systems. The conference highlighted the importance of collaboration between theory and ex...
VeriXiv's trust marker badges showcase rigorous verification checks, setting new standards for preprint integrity. The badges provide clear confirmation of the extensive checks each preprint undergoes before being made available on the site.
A 28-year-old woman was misdiagnosed with intussusception due to imaging similarities, but surgical removal revealed a rare ileal leiomyoma. Histopathology and immunohistochemistry confirmed the diagnosis, emphasizing the importance of combining imaging, histopathology, and immunohistochemistry for accurate diagnosis.
A new study reveals substantial differences in gene expression patterns between aging mouse and human skeletal muscle. Fewer than 5% of biological pathways show shared changes, emphasizing the need for cross-species targets in aging research.
A new study published in Genes & Cancer identifies activated beta-catenin as a key driver of aggressive pediatric osteosarcoma progression. The researchers found that cells expressing active beta-catenin exhibited enhanced invasive capacity and cancer-associated traits, suggesting a potential therapeutic target for this aggressive cancer.
Researchers investigated polyisoprenylated cysteinyl amide inhibitors (PCAIs) for their anticancer effects on pancreatic cancer cells with KRAS mutations. The compounds demonstrated strong activity against cell survival, migration, and invasion pathways. PCAI treatment caused hyperactivation of MAPK and PI3K/AKT pathways, leading to ox...
Cellular senescence has emerged as a key biological process linked to aging and age-related disease. Researchers have identified major features of senescence, including stable proliferative arrest and the senescence-associated secretory phenotype (SASP), which can influence inflammation and tissue dysfunction.
Sebaceous adenoma is a rare, slow-growing benign tumor arising from sebaceous glands. A new case report describes the clinical, histopathological, and immunohistochemical features of this tumor, highlighting its diagnostic challenges and importance of distinguishing it from more aggressive conditions.
Researchers found that CTHRC1, a secreted protein in tumor microenvironment, promotes colorectal cancer growth by limiting effective immune surveillance. The study suggests targeting CTHRC1 as a promising new strategy for future therapies.
A new PLOS report proposes a 'knowledge stack' publishing model to better support open science. This model connects articles with associated outputs like data, code, and methods to create a structured, open record of research. The report highlights the need for coordinated action beyond publishing to address challenges in existing models.
A new study found that DNA methylation aging biomarkers, such as GrimAge2 and DunedinPoAm, significantly mediate the relationship between social disadvantage and mortality risk. The findings suggest that epigenetic aging measures capture the cumulative effects of multiple social and environmental stressors.
The Bulgarian Society of Endocrinology's open-access journal, Endocrinologia, has moved to the ARPHA publishing platform developed by Pensoft. The platform provides a fast-track system for authors, reviewers, and editors, improving management and increasing international integration.
A new study reveals that nitrosylcobalamin, a vitamin B12 analog, selectively crosses the blood-brain barrier and targets glioblastoma tissue, demonstrating broad antitumor activity. The therapy also shows synergistic activity with existing treatments, offering a promising new strategy for treating this deadly brain cancer.
Research shows that adverts featuring people with a disability increase consumer attitudes towards brands and their products. Key findings include the benefits of disability inclusion and the importance of representing individuals with disabilities as capable advocates for a product or service.
The editorial highlights the growing importance of public health interventions to extend healthspan alongside lifespan. Key findings include the need for integrated strategies addressing environmental, metabolic, social, and behavioral exposures that accelerate biological aging and increase vulnerability to chronic disease. The authors...
Fayetteville State University and Taylor & Francis have partnered to provide FSU researchers with free access to over 2,500 journals. This three-year agreement eliminates costs associated with open access publishing, enabling FSU scholars to share their research globally and increase its visibility.
A rare case of high-grade laryngeal leiomyosarcoma was successfully treated with extended laryngectomy, left neck dissection, and adjuvant chemotherapy. Complete surgical excision remains the cornerstone of therapy, while multidisciplinary-guided adjuvant treatment may benefit selected high-grade or high-risk patients.
A new editorial provides guidance on writing constructive peer reviews, emphasizing key takeaways such as 'picking battles' and maintaining professional courtesy. The guidance aims to elevate scientific data quality while mitigating impacts on authors' reputation and mental wellbeing.
A new editorial proposes the use of agentic AI systems to address cancer-related malnutrition, a prevalent issue affecting up to 80% of patients. These systems aim to coordinate multiple functions simultaneously and support ongoing clinical decision-making throughout treatment.
The American Society for Nutrition has appointed Dr. Brian Lindshield as the new Interim Editor-in-Chief of Current Developments in Nutrition (CDN). With extensive experience and a strong record of leadership in academic nutrition, Dr. Lindshield will build on CDN's foundation for continued growth and innovation.
The FoSci Report 2026 examines individual paper-level fraud, coordinated criminal networks, systemic structural failures, and risks to government research. It charts the maturity and gaps in current research integrity practice, arguing that isolated infractions often signal more systemic issues.
A rare case of a small bowel GIST harboring concurrent KIT exon 9 duplication and SDHC mutation showed a strong response to high-dose imatinib, despite the presence of the SDHC mutation. Integrated molecular interpretation is crucial in GIST management.
The merger will enable significant operating efficiencies and combined scale with Project MUSE, while maintaining BioOne's flagship aggregation of bioscience research journals as a discrete product within Hopkins Press. The integration is expected to expand services, shared infrastructure, and sustain revenue for the nonprofit community.
The study reveals that human TERT is only compatible with non-human primate cells, while other species show limited or no telomere lengthening. This highlights the importance of using suitable preclinical models for telomerase-based therapies.
The International Osteoporosis Foundation is seeking an Editor-in-Chief for the European office of Osteoporosis International, a world-leading peer-reviewed journal focused on osteoporosis and metabolic bone diseases. The successful candidate will oversee content development, peer review, and strategic oversight of the journal.
The University of California and JMIR Publications have extended their institutional membership agreement, reinforcing a commitment to advancing open science. The multi-year extension supports over 450 articles published under the agreement, making open access publishing more equitable for UC researchers.
Researchers identified stage-specific gene expression changes that occur during cellular senescence, revealing an early immune-activating response and a shift in cellular priorities. This study offers new insight into the molecular mechanisms of aging and highlights potential therapeutic strategies for delaying age-related decline.
Dr Hendricks-Sturrup brings expertise in biomedical research, bioethics, and policy to lead the editorial board. Her experience will focus on disseminating high-quality research globally.
A new review found that lifestyle behaviors like physical activity and diet can positively modulate the gut microbiome of cancer patients, but these effects are often influenced by non-modifiable variables. The study also highlighted the role of intrinsic patient characteristics in shaping microbial composition.
A new hypothesis proposes that introducing Hydra-like gene expression patterns into rotifers could delay senescence and extend healthspan. The study focuses on conserved molecular pathways, including FoxO, which plays a central role in maintaining stem cell function and cellular resilience.
A recent study has found that epigenetic clocks are associated with cognitive impairment and dementia, but only specific epigenetic markers related to smoking exposure are linked to neurodegenerative changes. The study suggests that measures of epigenetic age acceleration capture different aspects of biological aging.
A rare case of mucinous ovarian carcinoma was reported in a postmenopausal woman, initially misdiagnosed as a pelvic abscess due to nonspecific symptoms and radiologic features. The diagnosis was confirmed after advanced imaging and tumor marker assessment. Early recognition is crucial for timely diagnosis and effective treatment of th...
The 12th ARDD meeting emphasized the importance of reversing biological age and identifying molecular mechanisms that can be targeted to modify them. Researchers presented new biomarkers and AI-designed proteins to develop novel therapeutics, with a focus on integrated, multi-targeted therapeutic strategies.
A rare scalp reaction resembling erosive pustular dermatosis was identified in a lung cancer patient treated with amivantamab following cranial radiotherapy. The reaction appeared to be related to impaired wound healing due to dual inhibition of EGFR and MET signaling pathways.
AEM expands its scope to cover the full breadth of modelling in agricultural and environmental sciences, introducing a structured range of article types for formal recognition. The journal applies FAIR principles to data, code, and models, requiring open access and reproducibility.
A new gene catalogue provides comprehensive insights into premature aging disorders, highlighting the central role of genome maintenance and DNA repair pathways. The catalogue organizes genetic and clinical information for 56 syndromes and 160 distinct clinical entities, offering a valuable framework for future research.
Research finds PDX1 gene plays a tumor-promoting role in human PCa cells by influencing metabolic pathways. The study identifies PDX1 as differentially hypermethylated in prostate cancer tissues, contributing to its aggressive characteristics.
The extension of the partnership aims to refine SnapShot's performance for live manuscript submission, providing enhanced author feedback and guidance on data sharing. The collaboration also focuses on iterative product development, expanding assessment graphs to accommodate additional data policies.
The International Association for Dental, Oral, and Craniofacial Research (IADR) and the American Association for Dental, Oral, and Craniofacial Research (AADOCR) have recognized a cover paper in their Journal of Dental Research. The award honors an aesthetically pleasing image that enhances the article's impact.
Oncology services are often excluded from emergency health priorities, resulting in delayed diagnosis and treatment interruptions. Vulnerable populations, including women and children, face advanced disease stages due to delays in care.
The Oncotarget Editorial Board discusses the journal's evolving approach to scientific integrity, highlighting the importance of modern image forensics tools. The article emphasizes the need for independent analytical and AI-based tools in journal evaluation.
Dr. Hongmei Wang joins Stem Cell Reports as an Associate Editor, bringing expertise in early embryo and placental development. Her laboratory investigates mechanisms governing embryonic and placental development, with potential for improving reproductive health outcomes.
The study found that immune checkpoint inhibitors significantly improved key clinical outcomes, including disease-free survival and distant metastasis-free survival. However, no clear improvement in overall survival was observed across studies, highlighting the need for careful patient selection and monitoring.