A novel method for monitoring on-treatment disease burden in high-grade serous ovarian cancer uses tumor-informed breakpoints-spanning ddPCR, detecting superior sensitivity and specificity compared to real-time PCR. The approach may enable sensitive and specific detection of minimal residual disease and early relapse detection.
The 'leaky pipeline' metaphor oversimplifies the systemic barriers faced by women and marginalized scholars in archaeology. New research highlights multiple forms of inequity that diminish productivity, limit collaborations, and reduce future generations of archaeologists.
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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Dr. Sara Simblett brings expertise in digital health innovation, patient engagement, and technology integration to JMIR Neurotechnology. Her research focuses on improving access, quality, and outcomes of care through digital interventions.
Impact Journals is exhibiting at the AACR Annual Meeting 2026 in San Diego, showcasing recent publications and discussing collaboration opportunities. The meeting highlights the latest advances in cancer science and medicine, with a focus on research impact, ethical standards, and scientific integrity.
Researchers found that D, L-buthionine-(S, R)-sulfoximine (BSO) replicates the anti-obesity effects of sulfur amino acid restriction without causing bone loss in male mice. The study suggests BSO as a promising tool for dissecting the beneficial versus deleterious axes of sulfur amino acid biology.
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A new study found that MYC amplification in metastatic prostate cancer is associated with reduced tumor immunogenicity, making it harder for the immune system to detect and attack the tumor. This reduction in immunogenicity was linked to poorer progression-free survival outcomes in patients with MYC-amplified tumors.
A working group of scholars and experts proposes three principles - transparency, credit, and accountability - to form the foundation for responsible authorship. The principles aim to address issues of gift, ghost, and coercive authorship and promote a culture of transparency and accountability in scientific research.
A multidisciplinary team proposes three principles for responsible authorship: transparency, credit, and accountability. The guidelines aim to address issues like gift or honorific authorship, ghost authorship, and coercive authorship, and promote a culture of trustworthiness in science.
Anand Balasubramani joins AAI with expertise in scientific publishing, program development, and community engagement. As CSPO, he will shape AAI's scientific agenda and oversee publications, education, and scientific affairs.
A new study reveals that p38 MAPK plays a key role in epigenetic regulation of fibrotic genes in lung fibroblasts, particularly in senescent cells. Pharmacological inhibition of p38 MAPK significantly reduced α-SMA and Col3A1 expression, suggesting a potential therapeutic target for treating age-related fibrotic diseases like IPF.
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GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
JMIR Publications has partnered with the University of Turku to provide unlimited open-access publishing, eliminating financial barriers and administrative hurdles for researchers. The partnership offers APC waivers for corresponding authors affiliated with the university, allowing them to publish in prestigious titles at no cost.
Prince of Songkla University and Taylor & Francis have partnered for a new open access agreement, supporting PSU's sustainable development mission and research impact. The partnership provides access to over 2,000 journals and eBooks, enabling PSU researchers to publish and share their work globally.
A new case report describes a large, calcified solid pseudopapillary neoplasm of the pancreatic head, emphasizing the importance of multidisciplinary evaluation and long-term follow-up for monitoring recurrence. The case underscores the diagnostic value of integrating imaging, histopathology, and immunohistochemistry.
A new metabolic theory proposes that a decline in glycolytic ATP production is the fundamental mechanism limiting lifespan. Species with an optimal rate of decline survived, suggesting that maintaining a stable glycolytic flux may support repair processes and tissue regeneration. The authors propose testing this hypothesis through expe...
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A recent study found that higher IL6 levels are associated with increased mortality, while genetically higher IL6R levels reduce all-cause mortality through cardiovascular mechanisms. The researchers suggest that IL6R antagonism may be a potential strategy for preventing cardiovascular disease.
The peer review process is facing a crisis due to an increasing number of manuscript submissions and a decline in willing peer reviewers. Researchers propose potential interventions to address this issue, including selecting high-quality reviewing and using machine learning to support editors. This could help maintain the credibility o...
A study profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells from young and old human cohorts, revealing that circMT-RNR2 levels are depleted in older cohorts and are involved in promoting the TCA cycle. Loss of GRSF1 reduces circMT-RNR2 levels, decreasing mitochondrial TCA intermediates and accelerating cellular ...
A new study examines the mechanisms, clinicopathological features, and management strategies of GI toxicity induced by targeted cancer therapies. The authors highlight the importance of close collaboration between oncologists, gastroenterologists, and pathologists to ensure accurate diagnosis.
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Advances in Pollinator Research is a community-driven peer-reviewed journal championing research from underrepresented regions and taxa. It aims to find and amplify solutions to pollinator decline through transdisciplinary collaboration.
Researchers developed a new single-cell transcriptomic clock called Tictock to measure aging in specific immune cells. The study found that COVID-19 and HIV alter T cell composition and accelerate the biological age of naïve CD8 T cells, while long-term antiretroviral therapy stabilizes T cell proportions.
Researchers highlight polyploidy-induced senescence as a coordinated biological program that may drive aging, tissue repair, and cancer risk. Polyploidization in healthy tissues could help maintain organ structure and barrier integrity, but its instability can promote chromosomal instability and malignant transformation.
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Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A new commentary raises concerns about editorial bias in scientific publishing, particularly in relation to COVID-19 vaccine safety and efficacy. The authors highlight the rejection of a case report and literature review that raised potential links between mRNA vaccines and rare blood cancers.
A case report investigates a woman's development of acute lymphoblastic leukemia and lymphoblastic lymphoma after receiving her second dose of the Pfizer-BioNTech COVID-19 mRNA vaccine, highlighting potential genetic and molecular mechanisms involved in disease pathogenesis.
Researchers found that an experimental compound SB-216 reduced the growth of pancreatic ductal adenocarcinoma cells by inhibiting oncogenic microtubules and mitochondrial function. This approach may reduce cancer cell adaptation and survival.
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Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
The expanded partnership strengthens researcher collaboration, increases open access opportunities, and fosters the impact of trusted knowledge. Researchers can discover and access relevant content through ResearchGate's Community Engagement Upgrade, while Taylor & Francis editors use new tools to grow their journals' communities.
JMIR Publications introduces a new merit-based reward system, Karma, to recognize and reward high-quality peer reviews. The program provides incentives tied to the depth and rigor of feedback, ensuring that reviewers are properly honored for their contributions.
The partnership integrates Dimensions Author Check API into ScholarOne Manuscripts, providing publishers with reliable insights into authors' and reviewers' publishing histories. This integration enables quick detection of unusual activities, such as retractions or atypical collaboration patterns.
Early recognition and surgical management are crucial in treating necrotizing fasciitis of the head and neck, a rare but life-threatening soft tissue infection. The authors emphasize the urgent need for coordinated care, including immediate surgery, broad-spectrum antibiotics, and airway protection to reduce mortality rates.
JMIR Publications invites journalists, researchers, and experts to contribute to its News & Perspectives section with in-depth analysis and commentary on digital health trends. The publication aims to provide well-researched analysis that goes deeper than headlines, with a focus on factual precision, integrity, and empowerment.
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Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
Sangwoo Lee brings over 20 years of experience in communications to lead MDPI's operations in South Korea. The appointment coincides with the launch of MDPI's 500th journal, Journal of Innovation, with Prof. Dr. Junic Kim as founding Editor-in-Chief.
Pensoft has welcomed the Swiss Journal of Palaeontology (SJP) and Swiss Journal of Geosciences (SJG) to its portfolio. Both journals have transitioned to open-access models, leveraging Pensoft's ARPHA publishing platform for streamlined processes and increased visibility.
A rare diagnosis of a giant solitary neurofibroma in a 13-year-old boy was successfully treated with microsurgery. The tumor's location deep within the thigh along the sciatic nerve made it challenging to diagnose and treat, but careful surgical technique and postoperative care ensured optimal outcomes.
The Estuarine Management and Technologies journal has been accepted into the Directory of Open Access Journals, a key scientific index. The journal's recognition signifies its compliance with global standards of ethics, transparency, and quality.
A new review proposes a two-stage model explaining how different determinants of aging interact to generate late-life disease. Early-life damage and late-life genetic activity are identified as key drivers of age-related illnesses.
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Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Review of Clinical Pharmacology and Pharmacokinetics has transitioned to an open-access model, with all published content available on the new ARPHA website. The journal benefits from ARPHA's one-stop publishing solution, high-level integrations, semantic enhancements, and advanced metrics.
Research finds age-related DNA methylation alterations in sperm may contribute to autism risk in offspring. Advanced paternal age is associated with specific changes in sperm DNA, influencing early development in children.
Researchers found that CD47 knockdown improves glucose homeostasis and alleviates dyslipidemia in aged male mice by reducing visceral fat and enhancing brown fat tissue function. This breakthrough suggests CD47 as a key regulator of age-related metabolic dysfunction.
JMIR Publications has partnered with Norwegian Agency for Shared Services in Education and Research (Sikt) to offer a flat-fee unlimited open access publishing model to researchers in Norway. The pilot program provides full waivers of Article Processing Fees, eliminating financial and administrative burdens on researchers and librarians.
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Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Dr Anita Bandrowski has been awarded the 2026 APE Award for Innovation in Scholarly Communication for her innovative work on open research infrastructure. Her efforts have improved scientific transparency and reproducibility through the use of persistent identifiers, increasing discoverability to over a million RRIDs.
A new hypothesis article proposes that HPV E6 and SARS-CoV-2 spike proteins could cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53. Laboratory studies suggest that combined viral pressures on tumor-suppressor pathways may contribute to cancer progression.
Researchers in Hong Kong will have greater opportunities to share their work with a global audience through an open access agreement between JULAC and Taylor & Francis. The partnership enables OA publishing in over 2,000 journals without payment of an OA article publishing charge.
The JMIR-Bibsam partnership has seen a 40% increase in annual publishing by Swedish authors, with over 130 digital health articles published without author payment. The renewed agreement simplifies the publishing process, allowing corresponding authors to publish immediately upon publication.
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Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.
The meeting report highlights the emerging importance of infection-driven senescence in understanding chronic diseases, including respiratory viruses like influenza and SARS-CoV-2. Researchers found that senescent cells contribute to persistent inflammation and reduced healing, particularly in older adults during chronic infections.
PeerJ expands its scope to encompass research in Chemistry, Materials Science, and some fields of Engineering. The expanded scope allows for greater collaboration across disciplines, with new opportunities for authors.
Environmental Health Perspectives has joined the ACS Publications portfolio, ensuring continued publication of high-quality research articles connecting environmental factors to human health. The journal will remain open access with waived article publishing charges until the end of 2026.
Researchers identified common aging-related alterations in genes involved in RNA splicing and processing across eight human tissues. These findings suggest a shared biological response to aging, pointing to the importance of RNA processing in accurate protein production.
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Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
A new study introduced epigenetic clocks in skeletal muscle from an Asian population, identifying DNA methylation sites associated with age and developing accurate age prediction models using NGS and SBE. The findings offer a reliable method for estimating age and its potential applications in forensic science.
A new study analyzed over 460,000 scientific abstracts to identify key themes, trends, and research gaps in aging research. The study found a growing separation between basic biological studies and clinical research, highlighting the need for integration to translate laboratory discoveries into medical applications.
Research found that older women with younger biological ages were more likely to experience increased depressive symptoms during the pandemic. The study suggests that this may be due to reduced social connections and daily routines, which can affect mental health.
Researchers at participating UK institutions will benefit from a renewed and expanded agreement offering over 2,400 journals with open access publishing options. The partnership also enables the expansion of AI use in licensed Taylor & Francis proprietary content for non-commercial research and educational purposes.
A systematic review found that pancreatic cancer surgery significantly increases the risk of new-onset diabetes mellitus (NODM), particularly in patients with known risk factors. The study analyzed 45 studies and found an overall incidence of NODM of 24.5%, with a higher rate in those who underwent distal pancreatectomy.
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Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers used machine learning to combine clinical data with biological markers, achieving 89.58% accuracy in predicting patient survival. The study identified key markers such as E2F8, WDR77, and hsa-miR-495-3p, which were associated with tumor growth and cancer development.
The journal has integrated ResearchGate to improve accessibility and impact of research on aging. This allows authors to connect their work with a wider network of peers, fostering collaboration and advancing understanding of the biology of aging.
Researchers found that higher levels of theobromine are associated with slower biological aging in humans, as measured by epigenetic markers such as DNA methylation and telomere length. The study suggests that theobromine may support healthy aging by influencing molecular epigenetic processes.
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The five-year partnership aims to equip Hiroshima University researchers with new open policies, promoting transparency and accessibility in their work. The collaboration will also provide practical guidance on open publishing pathways and encourage reform of the research evaluation system.
Associate Professor Shefaly Shorey has been appointed Editor-in-Chief of Midwifery, a leading international journal in midwifery and maternal health. She aims to champion high-quality, compassionate care through evidence-based practice, honours dignity, strengthens equity.
Researchers found that glycation stress, caused by methylglyoxal, promotes aortic stiffening and cellular senescence. Natural compound Gly-Low, containing nicotinamide and alpha-lipoic acid, reversed these effects and reduced stiffness in aging mice.
Researchers in Australia and Aotearoa New Zealand will have expanded open access publishing options through a new three-year agreement. The partnership supports fully open access journals and enables the expansion of AI use in teaching and research.
A case report describes a woman with radiation-induced cellular changes in her Pap smear that mimicked cancer recurrence. The study emphasizes the importance of recognizing these changes to prevent misdiagnosis and unnecessary medical procedures.
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This study found that older mice blood worsens Alzheimer’s-related changes, while younger blood improves memory and cognitive function. The researchers identified key proteins involved in neurodegeneration and inflammation, suggesting new avenues for targeting blood-borne factors to slow or modify disease progression.