Articles tagged with Peer Review
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
The integration of Prophy with ARPHA's editorial platform enables data-driven reviewer recommendations based on researcher expertise and publication history. This supports a more sustainable and balanced approach to peer review, reducing delays and fatigue.
Researchers at participating institutions can now publish without paying individual Article Processing Charges (APCs) in 65 peer-reviewed journals published by Pensoft or hosted on its ARPHA platform. This partnership ensures open access to research under FAIR principles, making data Findable, Accessible, Interoperable, and Reusable.
Early recognition and surgical management are crucial in treating necrotizing fasciitis of the head and neck, a rare but life-threatening soft tissue infection. The authors emphasize the urgent need for coordinated care, including immediate surgery, broad-spectrum antibiotics, and airway protection to reduce mortality rates.
A rare diagnosis of a giant solitary neurofibroma in a 13-year-old boy was successfully treated with microsurgery. The tumor's location deep within the thigh along the sciatic nerve made it challenging to diagnose and treat, but careful surgical technique and postoperative care ensured optimal outcomes.
A new review proposes a two-stage model explaining how different determinants of aging interact to generate late-life disease. Early-life damage and late-life genetic activity are identified as key drivers of age-related illnesses.
A study analyzing millions of biomedical and life science articles reveals that female-authored articles spend longer under review than comparable male-authored articles across most fields. The disparity underscores the ongoing issue of women's underrepresentation in academia, particularly in STEMM fields.
Research finds age-related DNA methylation alterations in sperm may contribute to autism risk in offspring. Advanced paternal age is associated with specific changes in sperm DNA, influencing early development in children.
JMIR Publications has partnered with Norwegian Agency for Shared Services in Education and Research (Sikt) to offer a flat-fee unlimited open access publishing model to researchers in Norway. The pilot program provides full waivers of Article Processing Fees, eliminating financial and administrative burdens on researchers and librarians.
Researchers found that CD47 knockdown improves glucose homeostasis and alleviates dyslipidemia in aged male mice by reducing visceral fat and enhancing brown fat tissue function. This breakthrough suggests CD47 as a key regulator of age-related metabolic dysfunction.
A new hypothesis article proposes that HPV E6 and SARS-CoV-2 spike proteins could cooperate in suppressing host defenses including tumor suppressor mechanisms involving p53. Laboratory studies suggest that combined viral pressures on tumor-suppressor pathways may contribute to cancer progression.
JMIR Publications' JMIR Neurotechnology journal now accepts submissions on novel technological advances for neurological disorders. Researchers can submit review articles exploring emerging technologies, such as neurofeedback, neurosurgery, and brain-machine interfaces.
A global review of COVID-19 vaccination and infection cases found associations between the two and certain types of cancer. The study analyzed 69 publications and identified potential biological mechanisms, including immune responses and inflammation.
A team of scientists found alternative explanations for data in topological quantum computing, challenging the field's progress. They proposed changes to increase experimental result reliability by sharing more data and discussing alternative explanations.
The JMIR-Bibsam partnership has seen a 40% increase in annual publishing by Swedish authors, with over 130 digital health articles published without author payment. The renewed agreement simplifies the publishing process, allowing corresponding authors to publish immediately upon publication.
The meeting report highlights the emerging importance of infection-driven senescence in understanding chronic diseases, including respiratory viruses like influenza and SARS-CoV-2. Researchers found that senescent cells contribute to persistent inflammation and reduced healing, particularly in older adults during chronic infections.
Researchers identified common aging-related alterations in genes involved in RNA splicing and processing across eight human tissues. These findings suggest a shared biological response to aging, pointing to the importance of RNA processing in accurate protein production.
A new study introduced epigenetic clocks in skeletal muscle from an Asian population, identifying DNA methylation sites associated with age and developing accurate age prediction models using NGS and SBE. The findings offer a reliable method for estimating age and its potential applications in forensic science.
A new study validates OVCAR3 as a reliable model for high-grade serous ovarian carcinoma, providing insights into disease behavior and potential therapeutic targets. The research also explores the effects of repurposed drugs on ovarian cancer cells, revealing promising results for treatment responses.
A new study analyzed over 460,000 scientific abstracts to identify key themes, trends, and research gaps in aging research. The study found a growing separation between basic biological studies and clinical research, highlighting the need for integration to translate laboratory discoveries into medical applications.
Research found that older women with younger biological ages were more likely to experience increased depressive symptoms during the pandemic. The study suggests that this may be due to reduced social connections and daily routines, which can affect mental health.
A systematic review found that pancreatic cancer surgery significantly increases the risk of new-onset diabetes mellitus (NODM), particularly in patients with known risk factors. The study analyzed 45 studies and found an overall incidence of NODM of 24.5%, with a higher rate in those who underwent distal pancreatectomy.
Researchers used machine learning to combine clinical data with biological markers, achieving 89.58% accuracy in predicting patient survival. The study identified key markers such as E2F8, WDR77, and hsa-miR-495-3p, which were associated with tumor growth and cancer development.
The journal has integrated ResearchGate to improve accessibility and impact of research on aging. This allows authors to connect their work with a wider network of peers, fostering collaboration and advancing understanding of the biology of aging.
Researchers found that higher levels of theobromine are associated with slower biological aging in humans, as measured by epigenetic markers such as DNA methylation and telomere length. The study suggests that theobromine may support healthy aging by influencing molecular epigenetic processes.
Researchers found that glycation stress, caused by methylglyoxal, promotes aortic stiffening and cellular senescence. Natural compound Gly-Low, containing nicotinamide and alpha-lipoic acid, reversed these effects and reduced stiffness in aging mice.
A case report describes a woman with radiation-induced cellular changes in her Pap smear that mimicked cancer recurrence. The study emphasizes the importance of recognizing these changes to prevent misdiagnosis and unnecessary medical procedures.
This study found that older mice blood worsens Alzheimer’s-related changes, while younger blood improves memory and cognitive function. The researchers identified key proteins involved in neurodegeneration and inflammation, suggesting new avenues for targeting blood-borne factors to slow or modify disease progression.
Researchers found that sudden cardiac death (SCD) among colorectal cancer patients decreased overall, but disparities remained based on age, sex, and geographic location. The study highlights the need for tailored heart monitoring and care strategies for cancer patients, particularly in underserved groups.
Two Russian scientists' conceptual similarities challenge conventional aging views. Their ideas about hyperfunction and elevation remain relevant to modern research. Golubev explores the historical connections between Dilman and Blagosklonny, highlighting their contributions to aging science.
Researchers at eight German institutions will benefit from the expanded agreement, which removes financial barriers to open access publishing in JMIR's portfolio of over 30 Gold Open Access journals. The partnership demonstrates a commitment to open science and bibliodiversity.
Researchers developed a machine learning tool, SAMP-Score, to identify compounds that induce senescence in p16-positive cancer cells. The tool successfully identified a promising candidate, QM5928, which triggers senescence without killing cancer cells.
The collaboration enhances transparency in scholarly publishing by certifying reviewer contributions and providing rewards. Reviewers can earn redeemable credits for reviews on partner journals, promoting participation and quality in the research community.
A new meta-analysis published in Aging-US found a significant association between hospitalization for infections and the risk of developing dementia. Adults hospitalized with infections were at an increased risk of all-cause dementia, especially after a single infection-related hospitalization, which can speed up cognitive decline.
A new review connects gut microbiome imbalances to obesity, metabolic syndrome, and colorectal cancer, highlighting the potential for diet and microbiome-based treatments. The study also explores racial and socioeconomic disparities in microbiome-related diseases, emphasizing the need for inclusive prevention strategies.
JMIR Publications has joined the International Association of Scientific, Technical and Medical Publishers (STM) to enhance research quality and trust. The publisher is integrating STM's Integrity Hub to prevent paper mills from operating with fake credentials.
A new study found that embryo arrest in IVF is more common with advancing maternal age but not directly related to chromosomal abnormalities. The research suggests two independent factors contribute to the number of euploid embryos available for transfer and overall ART success.
Researchers found that excess growth hormone disrupts liver metabolism, leading to molecular and cellular patterns similar to those in naturally aged livers. Reducing glycation stress can reverse these negative effects, improving liver health and physical function.
Researchers found that bifidobacterium can boost cancer treatment by regulating the immune system, reducing inflammation, and supporting anti-tumor responses. The probiotic also helps detoxify carcinogens and convert food-based substances into cancer-fighting agents, offering a promising natural ally for cancer prevention and treatment.
Clinical trial participants are calling for more inclusive and patient-centered cancer research, highlighting the need for transparent designs and improved communication. The authors propose various improvements to trial design and delivery, including expanding eligibility criteria and involving patient advocates in trial design.
A new study found that high tyrosine levels are associated with a shorter lifespan in men, while phenylalanine showed no such link. The researchers suggest that dietary adjustments, such as protein restriction, could help reduce tyrosine levels and support healthier aging.
Lymphomas develop resistance to targeted therapies through various mechanisms, including loss of target antigens, reactivation of growth pathways, and changes in tumor microenvironment. Researchers explore new treatment approaches, such as dual-target therapies and biomarker-guided therapy, to overcome these challenges.
Researchers found that lower LRIG1 expression is linked to more aggressive gliomas, a type of brain tumor. The study suggests that LRIG1 could serve as a useful marker for tumor severity and potentially as a target for future therapies.
Researchers found that combining L-BAIBA supplementation with voluntary wheel running exercise enhances musculoskeletal properties in middle-aged male mice. The study showed significant improvements in muscle strength, bone density, and reduced bone marrow fat.
The partnership designates JMIR Bioinformatics and Biotechnology as the official journal of MCBIOS, ensuring high-visibility publication of cutting-edge bioinformatics research. The agreement also provides benefits such as a discount on article processing fees and virtual education and training for MCBIOS members.
Researchers developed green-synthesized cerium oxide nanoparticles that combined cidofovir with nanoceria, enhancing anticancer activity and binding affinity to DNA and RNA. The new compound destroyed over 97% of cancer cells, suggesting a promising candidate for future cancer therapies.
A new gene editing technique, P3a mutagenesis, achieves near 100% success in creating precise DNA mutations. This method simplifies protein engineering, accelerating biomedical research and reducing costs.
A new study from the University of Lübeck introduces a 'lottery-first' approach to research grant allocation, increasing female representation by 10% and funded projects led by women by 23%. This method reduces estimated economic costs by two-thirds while maintaining scientific excellence.
A new case report describes the successful treatment of a 37-year-old woman with HER2-positive breast cancer that had spread to the membranes surrounding the brain and spinal cord. Trastuzumab deruxtecan, an antibody-drug conjugate, improved the patient's neurological symptoms and reduced cancer growth.
A new study found that faster biological aging measured by DNA-based epigenetic clocks is associated with greater cognitive decline and higher risk of mild cognitive impairment in Hispanic/Latino adults. The study highlights the potential of epigenetic clocks to track changes in brain health over time.
A new study found that alpha-synuclein triggers early gene expression changes in a Parkinson's disease model, revealing brain region-specific and systemic transcriptomic alterations. These changes may contribute to disease development and serve as potential biomarkers.
A rare case of a mucinous vulvar cyst was reported, which resembled a benign lipoma and caused lower abdominal and back pain. The cyst was surgically removed and confirmed to be non-malignant. The case underscores the importance of careful clinical examination in reproductive-age women presenting with vulvar masses.
The 2026 APE Award for Innovation in Scholarly Communication is now open for applications. The award celebrates innovators who bring new ways of thinking and collaborative approaches to improve scholarly communication. Past recipients include Dr Daniel Hook, CEO of Digital Science.
Researchers found that TRF1 protein loss led to leaner mice with altered metabolic profiles, including lower LDL cholesterol levels and improved blood sugar regulation. These benefits occurred without any detectable shortening of telomeres.
The Journal of the Optical Society of America B will make its content freely available worldwide if institutional subscribers meet a target. This move aims to balance author fees with community-driven open access options.
Researchers found that PAI-1 levels increase with age in both sexes, but only female mice lacking the gene experienced significant protection against age-related muscle and bone loss. Female mice maintained stronger grip strength and greater muscle mass, while showing less cortical bone loss.
A rare case of pancreatic Hodgkin lymphoma was reported, emphasizing the need for tissue diagnosis before definitive treatment. The patient's symptoms and imaging findings initially raised concern for pancreatic adenocarcinoma, but a biopsy revealed nodular sclerosis subtype of Hodgkin lymphoma.
Longevity clinics have emerged globally, offering advanced diagnostic services and customized lifestyle interventions to extend healthspan. However, concerns arise from lack of scientific validation, high costs, and limited access to populations most at risk for premature aging.
Researchers discovered that folate receptor beta is widely expressed in various pediatric and adolescent solid tumors, making it a promising target for improving tumor surgery accuracy. Pafolacianine, a next-generation dye targeting folate receptors, shows promise as a tumor-agnostic imaging strategy for pediatric cancer surgery.
Researchers found that overactive Runx1 gene accelerates age-related degeneration of intervertebral discs, causing premature cellular aging and unhealthy tissue changes. Targeting Runx1 may be a promising strategy to prevent or slow disc aging.
Epithelioid hemangioendothelioma is a rare and potentially malignant vascular tumor that can be mistaken for benign conditions. A new case report highlights the diagnostic challenges raised by rare tumors and emphasizes the need for vigilant evaluation of slow-growing swellings.