Research programs focused on child health and development. Covers pediatric research standards, infant nutrition and sleep, rare disorders, and childhood diabetes.
A decade-long review of Kids First DRC shows how shared data expands research opportunities across diseases, institutions, and scientific disciplines. The resource has supported findings with potential to improve diagnosis, risk assessment, and treatment in pediatric care.
A nationwide Japanese study of over 82,000 children found that exclusive breastfeeding for six months significantly reduces the risk of short sleep duration at one year of age. The study also suggests that breast milk's adaptability to infant needs and its melatonin content help regulate healthy sleep rhythms.
Researchers describe a novel disorder caused by biallelic loss-of-function variants in the TMEM63B gene, resulting in severe lung disease. The disorder presents with early onset respiratory distress, lung abnormalities, and developmental delay but no epilepsy.
The global incidence of type 1 diabetes nearly tripled over the past three decades, while health inequalities worsened. Lower-income countries carry a disproportionately large share of T1DM-related deaths and years of life lost due to disparities in access to insulin treatment and healthcare resources.
A new study by the Child Mind Institute found that more than one in four youth with mental health and neurodevelopmental concerns experienced negative online experiences, including cyberbullying and harassment. Despite this, only 20% of these incidents were reported through platform tools.
Research in Malawi finds that attempts to combat child marriage often neglect local perspectives and cultural norms, leading to challenges in implementing effective solutions. The study proposes an African feminist lens to address the issue, considering relationality, community, and cultural embeddedness to understand the problem.
A new Cochrane review found that sucrose can effectively reduce pain in newborn babies during painful procedures like venepuncture. The study examined 29 clinical trials involving over 2,700 babies and showed that a small amount of sucrose given before the procedure significantly reduces pain when combined with non-nutritive sucking.
A new study found that families prioritize VR features increasing physical activity over educational content, highlighting the need for research-based information on VR's impact on children. Families also emphasize the importance of safety controls to detect bullying or harassment on VR platforms.
A new survey reveals a significant difference between girls' and boys' well-being at school. Girls are found to be happier than boys due to stronger connections with their peers and feeling safe at school. In contrast, boys tend to score lower in academic subjects like reading and science but excel in physical education.
Researchers are expanding options for patients with hard-to-treat cancers using a personalized approach that identifies effective therapies by testing large libraries of drugs on living tumor cells. The approach has shown stronger responses than initial findings, suggesting it can reveal opportunities missed by traditional methods.
The American Pediatric Society has reinstated the APS Howland Visiting Professor Program at Vanderbilt University School of Medicine, enabling renowned pediatric leader Bonnie W. Ramsey, MD, to share her expertise and engage with academic professionals.
A new study published in the ECNU Review of Education warns that digital inequality has not disappeared but has become more hidden. School leaders play a critical role in inequities, particularly in how technology is used and in the social context of its implementation.
Dr. Tara O. Henderson is the recipient of the 2026 Norman J. Siegel New Member Outstanding Science Award, recognizing her groundbreaking research and dedication to improving outcomes for children with cancer. She has established a distinguished record as a mentor and educator, shaping the careers of numerous physicians and scientists i...
Researchers found a novel link between shared brain-gene patterns and autism symptom severity in children with autism and ADHD. The study suggests that focusing on specific symptom dimensions and their biological correlates may lead to more precise recognition and treatment approaches.
Dr. Harolyn Belcher is recognized for her significant contributions to advancing child and adolescent health, well-being, and equity through quality improvement, advocacy, practice, or research. Her work has had a far-reaching impact on the lives of marginalized communities.
The Gabriella Miller Kids First Data Resource Center has released its 37th study on extracranial germ cell tumors, a rare group of childhood cancers. The dataset comprises information from 393 children and young adults, including inherited genetic data and tumor-specific changes.
Pennington Biomedical researchers will participate in numerous panels and presentations during the conference, sharing their latest findings on obesity treatment and prevention. The institution is well-represented at the event, with faculty members among the experts leading courses, presentations, and speaker panels.
The termination of thousands of federal grants has raised ethical concerns about clinical trial closures, particularly among children and adolescents. Researchers argue that sudden stops can break trust and harm participants, violating long-standing principles.
The European Society of Endocrinology has released the EndoCompass Research Roadmap, a major new initiative to align research efforts and improve funding strategies for hormone-related health challenges. The roadmap identifies specific research needs across eight endocrine specialties and five cross-cutting areas.
The Variant Workbench enables researchers to explore genetic data in a single, integrated workspace, linking genomic information with clinical conditions. By reducing data complexity, the tool facilitates scientific discovery and accelerates pace of research.
Dr. Wendy K. Chung, MD, PhD, receives the 2026 Mary Ellen Avery Neonatal Research Award for her outstanding contributions to neonatal health through basic or translational research. Her discoveries have transformed newborn screening and improved health outcomes for children with congenital anomalies.
Researchers have identified four distinct profiles of Nonverbal Learning Disability, each with different strengths and challenges. The study suggests that current diagnostic criteria may be too broad, highlighting the importance of individualized approaches to care for children with NVLD.
The SURPASS-PEDS trial shows that tirzepatide significantly improves HbA1c levels, BMI, and fasting glucose in children aged 10-17 years with type 2 diabetes. The study demonstrates sustained improvements over a year-long period, making it a potential safe and efficacious treatment option for youth-onset type 2 diabetes.
The Gabriella Miller Kids First Pediatric Research Program has released its 36th study, introducing significant new data updates to two existing studies. These advances aim to uncover the genetic foundations of childhood cancers and congenital conditions. With over 110,000 data files available, researchers can explore publicly accessib...
A cohort study found that obesity in childhood cancer survivors is linked to an increased risk of developing multiple subsequent neoplasms. Conversely, high levels of physical activity are associated with a reduced risk of these cancers.
Research suggests that antibiotics taken during infancy, especially in the first three months, may lead to earlier onset of puberty in girls. The study, which analyzed data on over 322,000 children in South Korea, found a significant association between early antibiotic exposure and increased risk of central precocious puberty.
A cohort study of 12,480 mother-offspring pairs found that pre-pregnancy obesity, gestational diabetes, and hypertensive disorders of pregnancy are associated with increased offspring blood pressure. These risk factors may also promote a faster rate of blood pressure change from age 2 to 18 years.
A study published in Journal of the American Academy of Child & Adolescent Psychiatry found that adolescents who are more physically active have a lower risk of developing depression symptoms. The research followed 873 participants from age 6 to 18 and found that physical activity protected against depression symptoms in adolescence.
The MyoStep project represents a significant advancement in pediatric mobility aids for children with cerebral palsy, addressing motor impairments that restrict participation in physical activities. The soft power suit provides a lightweight, discreet solution tailored to fit seamlessly into the lives of children and their families.
A new study suggests that higher cigarette taxes can significantly improve childhood survival rates, particularly among the poorest children. The research found that increasing tax on cigarettes could narrow the socioeconomic gap in child mortality rates and save over 280,000 lives annually.
Researchers at Amsterdam UMC have developed a new diagnostic test that measures CRP protein in cerebrospinal fluid to quickly diagnose bacterial meningitis. The test has been shown to be very reliable and can start treatment within half an hour of diagnosis.
Researchers found it takes parents about a year to attune to their child's attitudes towards school once they start education. By Year 1, parental perceptions of how a child feels about school most closely match responses given by the child when they were in Reception class a year earlier.
The CHLA team has demonstrated the possibility of using genetically engineered pig hearts as a 'bridge' to heart transplant for critically ill babies. Eight baboons have survived with a pig heart, with one living for nearly 21 months.
A virtual crisis prevention program for autistic children and their families has shown significant improvement in confidence, preparedness, and knowledge around crisis management. The 3-session program guided caregivers through a four-stage framework, equipping them with practical tools to navigate challenging situations.
A study published in Hepatology reveals that children with metabolic dysfunction-associated steatotic liver disease (MASLD) are at a significantly increased risk of premature death and serious long-term health complications. The mortality rate was found to be nearly 40 times higher than the national average.
The Pediatric Heart Transplant Alliance is a coalition of six leading organizations working to advance pediatric heart transplantation through research, education, and advocacy. The alliance aims to improve patient outcomes and quality of life for children with transplanted hearts.
Researchers used umbilical cord blood to analyze genetic changes linked to metabolic dysfunction in children. The study found multiple regions of altered DNA associated with metabolic issues later in childhood.
Researchers found that babies from insecure backgrounds can still follow social cues, sparking hope for their development. The study used eye movement measurements and interviewed parents to assess a child's background and circumstances, concluding that some skills are intact despite trauma.
A longitudinal and multi-country study found that parental warmth during childhood and adolescence predicts positive world beliefs, while other experiences have little impact. The study provides insights into human development across diverse cultural contexts.
A recent psychological study found that high levels of toxic metals in mothers and newborns are associated with early childhood development problems. Breastfeeding during the first six months is generally considered favourable to an infant’s health, but exposure to toxic metals reduces its intensity and duration.
Researchers discovered that infants at 15 months old can use conversational contexts to form initial representations of new words, which helps them later recognize the word when the object is visible. By 12 months, infants may not yet have enough familiarity with familiar words to begin forming a representation of a new word's meaning.
A new report warns of a sharp decline in pre-primary education aid, highlighting the scale of inequalities between rich and poor nations. The total aid spent on pre-primary education was the second highest since records began, but represented just 1.2% of global education aid.
Long COVID can result in significant health risks for young people, including chronic kidney disease, gastrointestinal symptoms, and cardiovascular conditions. Studies found that children with COVID-19 face elevated risks of developing these conditions, even years after the initial infection.
The Kosair for Kids Center for Pediatric NeuroRecovery is expanding its facilities to increase treatment capacity by 50%, allowing up to 24 children per day to receive life-changing therapies. The new 12,500-square-foot space will also enhance research collaboration and improve patient care.
Research from the University of Ottawa reveals distressing levels of violence in Ontario schools, with workers facing normalization of violence and lack of support. The report highlights the consequences of austerity cuts on education systems, leading to overcrowded classrooms, limited resources, and delayed access to assessments.
Researchers at UT Arlington's CIHI are developing innovative solutions to address complex health needs in children with disabilities, behavioral health issues, and medical conditions. The projects aim to improve healthcare services, enhance quality of life, and promote healthier aging through cutting-edge research and model organisms.
Researchers at UCLA Health are launching a clinical trial to test whether wearable nerve stimulation can ease ADHD symptoms in children with prenatal alcohol exposure. The study aims to improve focus and behavior by gently stimulating the trigeminal nerve, which is linked to attention and executive function.
New research found that COVID vaccines significantly reduced the risk of long COVID in children and adolescents. Vaccination was about 95% effective in preventing long COVID in some cohorts, primarily due to its ability to prevent initial infection.
Researchers developed a new method that uses simple grayscale eye photos to predict anemia in children. The technique analyzes patterns and textures in the conjunctiva of the eye, avoiding problems caused by different light conditions or camera models.
Research from Rutgers Health finds that children exposed to paternal depression at kindergarten entry are more likely to have behavioral difficulties and poor social skills at age 9. Fathers' mental health is crucial in supporting their children's development, and early intervention can help improve well-being for both parents and kids.
Researchers found that repeated antibiotic use before age 2 is associated with a higher risk for asthma, food allergies, and hay fever later in life. The study suggests that judicious use of antibiotics in children under 2 may impact long-term health outcomes.
The COVID-19 pandemic has exposed and magnified the mental health vulnerabilities of children from disadvantaged backgrounds. Research highlights the surge in anxiety, stunted social development, and loneliness, potentially leading to lifelong psychological wounds.
A novel cannula delivery system allows repeated, nondisruptive delivery of imaging agents to the mouse brain during long-term multiphoton microscopy. This innovation enhances longitudinal studies on brain function, disease progression, and potential treatments.
Research published by the American Psychological Association finds that positive maternal parenting in childhood can foster key personality traits such as openness, conscientiousness, and agreeableness. Twin study data suggests that modest changes in these traits could lead to significant population-wide benefits.
Two studies found concerning levels of phthalates, flame retardants, and UV-filters in bedroom air around children's beds, linked to neurological and reproductive problems. The researchers call for stronger regulations on the use of these chemicals in children's mattresses and recommend parents take actions to reduce exposure.
Researchers at the University of Missouri's Thompson Center for Autism and Neurodevelopment have found that behavior at 9 months old can indicate a 1-year-old's likelihood of being at risk for autism. Parent surveys reported fussiness, irritability, and difficulty calming down were associated with early signs of autism by 12 months.
A recent study by University of Fukui researchers found that impaired empathy in parents who experienced childhood trauma increases the risk of abusive parenting, perpetuating a cycle of abuse. The study highlights the importance of targeted interventions, such as mental health support and parenting programs, to break this cycle.
A study of 296 Canadian and 309 Hong Kong children found that those with feminine-behaving peers showed signs of fear and disgust, while those with masculine-behaving peers displayed happy emotions. This suggests that children learn to imitate these emotional responses from their peers, family members, and media.
A study of over 500 schools in Canada found that 98% exhibit risky driving behaviors, including double parking and not obeying traffic controls. The authors suggest improvements to the built environment and parental education to address this serious issue.
A new study from the University of Georgia found that children who attend school-based pre-K in Georgia start kindergarten with better preparedness than their peers, scoring 6 percentiles higher in reading and math. However, these academic gains fade by fourth grade, raising questions about how to sustain them.