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New mechanisms and therapeutic possibilities for heart failure uncovered by scientists at the Lewis Katz School of Medicine at Temple University and Johns Hopkins University

Researchers at Temple University and Johns Hopkins University found that brain-derived neurotrophic factor (BDNF) loss underlies post-myocardial infarction heart failure. BDNF levels can be replenished therapeutically, abolishing damage to heart tissue and enabling recovery.

SourceTemple University Health System·JournalCirculation Research·DateMar 30, 2023

Scientists of the University of Malaga found the origin of congenital coronary fistulae

Scientists have discovered the origin of congenital coronary fistulae, a condition where abnormal connections form between blood vessels and heart chambers. This study may help improve early diagnosis and treatment of this condition, which affects up to 0.2% of patients undergoing medical examination.

SourceUniversity of Malaga·JournalExperimental & Molecular Medicine·TypeExperimental study·DateMar 30, 2023

How to prepare for ocean acidification, a framework

An international research team has developed a framework to evaluate government preparedness for ocean acidification, a pressing threat to marine ecosystems. The framework identifies six aspects of effective policy and specific indicators, enabling policymakers to assess their own preparedness and identify areas for improvement.

SourceCalifornia Academy of Sciences·JournalEnvironmental Research Letters·DateMar 28, 2023

Cooking up plasmas with microwaves

Researchers at Kyoto University have successfully created stable plasmas using microwaves, a key step towards harnessing nuclear fusion's massive energy potential. The team identified three crucial steps in plasma production and used Heliotron J to generate the dense plasmas.

SourceKyoto University·JournalProblems of Atomic Science and Technology·TypeExperimental study·DateMar 28, 2023

ENGOT-EN6-NSGO/GOG-3031/RUBY trial results: The new standard of care in advanced/recurrent endometrial cancer

The ENGOT-EN6-NSGO/GOG-3031/RUBY trial reveals significant improvements in progression-free survival and overall survival for patients with primary advanced or recurrent endometrial cancer when treated with dostarlimab in combination with standard of care carboplatin/paclitaxel. The new treatment regimen offers a substantial increase i...

SourceThe GOG Foundation Inc·TypeRandomized controlled/clinical trial·DateMar 27, 2023

LSU Health New Orleans study suggests interprofessional team training could prove effective in AUD prevention & treatment

A new LSU Health New Orleans study suggests that single, focused Interprofessional Education-based exercises can significantly decrease stigma associated with alcohol use and improve knowledge and confidence in screening for Alcohol Use Disorder (AUD). The exercise led to substantial improvements in student understanding of AUD risks, ...

SourceLouisiana State University Health Sciences Center·JournalBMC Medical Education·TypeSurvey·DateMar 21, 2023

Impact of Covid-19 pandemic on incidence of long-term conditions in Wales

A population data linkage study found fewer people in Wales diagnosed with long-term conditions in 2020 and 2021 than expected, indicating a potential backlog of undiagnosed patients. This disparity affects chronic obstructive pulmonary disease (COPD) and anxiety disorders, corresponding to over 30 and 80 missing diagnoses respectively.

SourceSwansea University·JournalBritish Journal of General Practice·TypeData/statistical analysis·DateMar 13, 2023

A European consortium achieves record efficiency in direct conversion of CO2 and H2O into sustainable fuels using earth-abundant materials

A European consortium has achieved a world-record solar-to-fuel efficiency of over 10% in converting CO2 and H2O into sustainable fuels using sunlight. The innovative cell produces hydrogen continuously (24/7) without the use of critical raw materials.

SourceInstitute of Chemical Research of Catalonia (ICIQ)·JournalEnergy & Environmental Science·DateMar 13, 2023

Wayne State researcher publishes new research to bring Brillouin microscopy closer to widespread use in diagnostic medicine

Researchers have improved Brillouin microscopy to acquire mechanical images of cells and tissues at speeds 50-100 times faster than existing methods. This innovation enables the investigation of cell behaviors in real-time, with potential applications in cancer diagnosis and embryonic tissue development.

SourceWayne State University - Office of the Vice President for Research·JournalNature Methods·TypeImaging analysis·DateMar 10, 2023

Meta-analysis shows association between autism in children and cardiometabolic diseases

A meta-analysis of 34 studies found a significant association between autism spectrum disorder (ASD) and increased risks of developing diabetes, dyslipidemia, and heart disease. Children with ASD were more likely to develop these metabolic complications, prompting clinicians to monitor them closely.

SourceTexas Tech University Health Sciences Center·JournalJAMA Pediatrics·TypeMeta-analysis·DateMar 10, 2023

MSU-led international research network welcomes new Ibero-American partner to advance nuclear astrophysics

The International Research Network for Nuclear Astrophysics (IReNA) has partnered with the Ibero-American Network of Nuclear Astrophysics (IANNA) to enhance knowledge in nuclear astrophysics. The new collaboration will enable researchers from both networks to access cutting-edge technology and combine their expertise, resources, and ac...

SourceMichigan State University Facility for Rare Isotope Beams·TypeComputational simulation/modeling·DateMar 10, 2023

Group exercise program for older adults led to more independent exercise despite pandemic restrictions, MU study finds

A study by the University of Missouri found that older adults who completed an eight-week resistance training program maintained long-term exercise habits and increased their physical energy despite COVID-19 restrictions. The Stay Strong, Stay Healthy program improved participants' sleep, balance, flexibility, and self-confidence in da...

SourceUniversity of Missouri-Columbia·JournalJournal of Sports Sciences·TypeSurvey·DateMar 8, 2023

Researchers take a step towards turning interactions that normally ruin quantum information into a way of protecting it

Researchers developed a technique to predict how quantum systems behave when connected to their environment, turning a problem into a solution. The approach combines techniques from quantum many-body physics and non-Hermitian quantum physics, providing a crucial tool for real-world applications of quantum technology.

SourceAalto University·JournalPhysical Review Letters·DateMar 8, 2023

SMART researchers develop novel combination bacterium- and host-targeted therapy for treating vancomycin-resistant bacterial infections

Researchers develop a novel combination therapy using mitoxantrone and vancomycin to treat vancomycin-resistant Enterococcus faecalis (VRE) infections. The therapy stimulates the host immune system, accelerating wound healing and killing bacteria more effectively.

SourceSingapore-MIT Alliance for Research and Technology (SMART)·JournalScience Advances·TypeExperimental study·DateMar 7, 2023

Mass General Brigham study finds virtual care team strategy improved treatment for heart failure patients

A virtual care team consisting of physicians and pharmacists improved the adoption of life-saving therapies in patients with heart failure, leading to increased use of evidence-based treatments and better patient outcomes. The strategy was safe and effective, with comparable length of stay and safety events between the groups.

SourceMass General Brigham·JournalJournal of the American College of Cardiology·TypeRandomized controlled/clinical trial·DateMar 6, 2023

Too many babies are still dying from serious intestinal disease, as improvements slow and disparities persist

A recent study found that Black infants in the US were disproportionately affected by necrotizing enterocolitis, with higher mortality rates compared to White infants. Despite overall improvements in NEC-related deaths between 1999 and 2020, racial disparities persisted.

SourceNecrotizing Enterocolitis (NEC) Society·JournalJAMA Network Open·TypeData/statistical analysis·DateMar 3, 2023

Biologists, chemical engineers collaborate to reveal complex cellular process inside petunias

A team of Purdue University scientists has identified a protein that plays a key role in helping petunias emit volatiles, challenging the idea that simple diffusion is responsible. The study focuses on how volatiles cross the cell wall, a barrier that separates the cellular interior from the plant's outermost protective layer.

SourcePurdue University·JournalNature Communications·TypeExperimental study·DateMar 2, 2023

Wastewater study monitors Houston schools for viral threats

A new study by Rice University and Houston Health Department shows that wastewater-based monitoring is an effective way to detect viral outbreaks in schools. The system allows for early detection of illnesses such as influenza, COVID-19, and RSV, enabling strategies to stop the onset of potential outbreaks.

SourceRice University·JournalWater Research·TypeData/statistical analysis·DateMar 1, 2023

Home-based cardiac rehabilitation may help people live longer

A new study published in the Journal of the American Heart Association found that participating in home-based cardiac rehabilitation was associated with a 36% lower likelihood of death from heart-related complications among US military veterans within four years. The study analyzed data from 1,120 veterans who enrolled in a 12-week hom...

SourceAmerican Heart Association·JournalJournal of the American Heart Association·DateMar 1, 2023

The largest genomic study of rare cancer metastathic pheochromocytoma identifies patients at highest risk of metastasis and those who would respond to immunotherapy

Researchers have identified markers associated with an increased risk of metastasis in patients with metastatic pheochromocytoma, allowing for personalized clinical management. The study also identifies patients who could benefit from immunotherapy treatments, paving the way for potential new therapies.

SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalNature Communications·TypeObservational study·DateFeb 28, 2023

Engineered wood grows stronger while trapping carbon dioxide

Rice University scientists have developed a method to engineer wood that traps carbon dioxide while increasing its strength. This process involves removing lignin and hemicellulose from the wood and replacing them with metal-organic framework particles, making it a sustainable alternative to traditional materials.

SourceRice University·JournalCell Reports Physical Science·TypeExperimental study·DateFeb 16, 2023