Articles tagged with Depression
A study published in Molecular Psychiatry reveals that deep brain stimulation (DBS) to the superolateral branch of the medial forebrain bundle can alter metabolic brain changes over 12 months, making it a strong potential therapy for treatment-resistant depression. The results showed that 8 out of 10 patients experienced significant sy...
Symptoms of cardiovascular diseases, including heart attack and heart failure, can profoundly affect quality of life. The American Heart Association scientific statement highlights the importance of tracking symptoms to detect changes and progression.
A systematic review and meta-analysis of 26 studies involving over 100,000 women found that mothers with a family history of psychiatric disorders are at almost twice the risk of developing postpartum depression. The findings suggest that family history may be a significant risk factor for postpartum depression.
A new study identifies an optimal rTMS treatment regimen for older adults with treatment-resistant depression. After six weeks of treatment, the degree of improvement in older and younger adults is the same.
A randomized controlled trial found that virtual museum visits significantly improved the health of seniors stuck at home, reducing social isolation and improving well-being, quality of life, and frailty. The study recruited 106 participants aged 65 and older who attended guided tours online once a week for three months.
A large meta-analysis suggests that vitamin D supplementation may alleviate depressive symptoms in adults with depression. The analysis included 41 studies and found that vitamin D was more effective than a placebo in alleviating symptoms. However, the results were limited by study heterogeneity and risk of bias.
A new study from the University of Missouri-Columbia found that American military veterans are less willing to seek treatment for sleep and alcohol use problems compared to physical health issues. Discrimination experiences also play a significant role in reducing treatment-seeking among veterans of color.
Researchers at HKUMed & CityU discover that transcorneal electrical stimulation can alleviate depression-like symptoms and improve cognitive function in animal models. The technique also induced the expression of genes involved in brain cell growth, offering a potential new treatment for Alzheimer's disease.
A study found that LGBTQ+ youth in both highly supportive and less supportive communities experience high rates of depressive symptoms and stigma. The research suggests that systemic changes are needed to address the negative impact of broader social stigma on mental health.
New research reveals that only 1 in 5 Syrian children living in refugee camps exhibit resilience to mental health problems. The study found that factors such as the child's environment, caregiver interactions, and access to resources significantly impact their ability to recover from war trauma.
A study published in NeuroReport reveals that ultrasound exposure improves depressive behavior in a rat model of depression. OB rats exposed to USV had significantly lower hyperemotionality scores and plasma corticosterone levels than unexposed rats, suggesting potential anti-depressant effects.
A new AI-based dynamic brain imaging technology has been introduced by Carnegie Mellon University, which can map out rapidly changing electrical activity in the brain with high precision and speed. The technology uses deep learning approaches to translate scalp EEG signals back to neural circuit activity without human intervention.
Researchers found that genetic variations in the serotonin 5-HT2A receptor impact its interaction with psychedelic drugs. Seven variants uniquely altered the receptor's response to psilocin, LSD, 5-MeO-DMT, and mescaline.
Research found that everyday discrimination during COVID-19 led to increased odds of moderate to severe depression and suicidal ideation, particularly among Hispanic/Latino and Asian/Pacific Islander participants. The study highlights the need for clinicians and society to address the toll of discrimination on mental health.
McGill University researchers identify ventral striatum as key area in brain decisions between future pain and profit, potentially advancing treatments for disorders characterized by excessive avoidance. The study uses brain scans to monitor activity and machine-learning algorithms to predict participants' choices.
Researchers at UNC School of Medicine have identified seven genetic variants that uniquely affect the response to four psychedelic drugs. These findings suggest that patients with different genetic variations may react differently to psychedelic-assisted treatments.
A large-scale survey of 62,000 participants found a significant association between everyday discrimination and moderate to severe depressive symptoms during the pandemic. Participants from Hispanic or Latino and non-Hispanic Asian backgrounds who experienced racism were at higher risk for these conditions.
Researchers say stereotypes and stigma surrounding mental illness can lead to poor workplace behavior. Employees with mental illnesses may face fear of discrimination, which drives inauthenticity and counterproductive work behaviors.
Research teams at Mass General Brigham will conduct large-scale studies to treat acute suicidal depressed state and bipolar depression. The studies aim to compare the effectiveness of various treatments and provide valuable data on treatment outcomes.
A new study found that experiencing the death of a spouse due to COVID-19 may be worse for mental health than deaths from other causes. People who lost a spouse to COVID-19 were more likely to report symptoms of depression and loneliness. The study underscores the ongoing health risks posed by the pandemic, even to those who have not b...
The American College of Physicians (ACP) has issued a position paper on the ethical use of genetic testing and precision medicine in internal medicine. The guidelines address key issues such as incidental findings, education for physicians and patients, and counseling needs. ACP emphasizes the need for ongoing surveillance and anticoag...
Salk researchers identify neurotensin as a key molecule in the brain's valence assignment process, which associates good or bad feelings with memories. The discovery could lead to a better understanding of why some people retain more negative emotions than positive ones, and may pave the way for new therapeutic targets.
Research at the University of Reading found that high-dose Vitamin B6 supplementation reduced feelings of anxiety and depression in young adults. The study links Vitamin B6 to its calming effect on the brain, which may help alleviate mood disorders.
A comprehensive review of research on serotonin and depression found no link between the two, contradicting long-held theories. The study suggests that antidepressants' effectiveness may be due to managing stressful life events rather than correcting chemical imbalances.
A recent study published in Frontiers found that older patients respond equally well to rTMS but with slower onset of effects compared to younger patients. The researchers suggest revising treatment protocols to consider longer courses for older adults, making this treatment more accessible.
Researchers found associations between perceived discrimination and epigenetic aging in US middle-aged and older adults. Depressive symptoms were identified as a potential mediator in these relationships, particularly among women and White adults.
The 9th World Congress on Targeting Microbiota will discuss recent advances in microbiome research, including the potential of naked mole rat's gut microbiome to extend human lifespan. The congress also explores gene editing and microbiome therapy for depression and cancer immunotherapy.
A new study published in Blood Advances found that caregivers for people with multiple myeloma experience higher levels of anxiety and depression compared to the patients they support. The study also highlights a critical gap in communication between providers and caregivers regarding the terminal nature of the disease.
A survey study found an association between childcare stress and burnout, anxiety, depression, and intent to reduce hours or leave the job. Healthcare workers experienced increased stress and burnout during the pandemic, leading to a higher likelihood of leaving their jobs.
A study of 428 adults found that frequent fruit consumption is linked to lower depression scores and higher mental wellbeing, independent of overall quantity. In contrast, nutrient-poor savoury snacks like crisps were associated with increased 'everyday mental lapses' and symptoms of anxiety, stress, and depression.
Researchers found that six years before a stroke, people who later developed a stroke had similar scores to those who didn't have a stroke. However, at two years before the stroke, scores of those who had a stroke started increasing, reaching a total of about 2.1 points and staying high for 10 years after the stroke.
Researchers found that a gene called Rgs2 plays a crucial role in depression-related behavior, particularly in women. Increasing this gene's expression in the nucleus accumbens reversed stress effects and improved motivation in female mice, suggesting a potential molecular mechanism contributing to the lack of response to depression tr...
A study found that pharmacogenomic testing can help providers avoid prescribing antidepressants with undesirable outcomes. The test, which analyzes genes related to drug metabolism, resulted in a significant improvement in depression symptoms compared to usual care.
A study from the University of Kansas found that social support was crucial in predicting good sleep quality among individuals with multiple sclerosis. The research, conducted during the pandemic, revealed that tangible and positive social interaction support significantly predicted better sleep quality.
A UBC Okanagan study published in Nature-Scientific Reports found that regular small amounts of psilocybin improved mood, mental health, and psychomotor ability in participants. Microdosing was associated with reduced symptoms of depression, anxiety, and stress, particularly among those over 55.
A long-term high-fat diet has been shown to cause significant weight gain and metabolic disorders in mice, leading to anxiety, depression, and worsening Alzheimer's disease. The study suggests a clear link between chronic obesity and diabetes with cognitive decline.
Grieving a close family member can significantly increase stress levels, contributing to poor prognosis in heart failure patients. The study found that bereavement was associated with increased mortality risk, particularly after death of a child or spouse/partner.
A study found that patients and their caregivers agreed on the severity of physical symptoms like pain and functionality, but disagreed on psychological symptoms like depression and anxiety. The researchers also noted that caregivers who were under stress overreported their patient's symptoms.
Research from Penn State and Michigan State found paternal depression symptoms associated with adolescent depression and behavior problems, even among non-genetically related families. Parent-child conflict was a key factor contributing to these effects.
The July issues of The American Journal of Psychiatry and Psychiatric Services feature new neuroscientific advances addressing major depression, anhedonia, and cognitive deficits. Research reports highlight the provision of care among underserved populations, including Hispanic communities with declining mental health services.
A study published by researchers at the University of Colorado Anschutz Medical Campus found that psychiatric drugs imipramine and olanzapine can improve symptoms of Alzheimer's disease, including boosting cognition and reversing clinical diagnoses.
A UC San Diego study reveals six overarching themes contributing to physician job stress and suicide, including physical health deterioration and financial stress. The research calls for short-term solutions like improved access to primary care and long-term changes to address workplace culture and self-care.
A recent study from Penn State's Center for Childhood Obesity Research found that second-born children in families where mothers received responsive parenting training slept an average of 40 minutes longer per night. The training also promoted healthier feeding practices and lower body mass indices (BMIs) in infants.
A Rutgers study found that parental depression affects about one in five US families and can have severe consequences on children's health. The research suggests that increased screening for parental depression across a wider age range has the potential to identify families in need of resources.
Scientists at Tohoku University have identified specific brain wave patterns related to social behavior in mice. These findings provide a unified understanding of brain activity underlying social behavior and its deficits in disease.
Patients experiencing dissociative symptoms after trauma may be at high risk of developing severe post-traumatic stress, depression, anxiety, and social impairment. Early interventions are crucial for these individuals.
Researchers found hyperactive amygdala-pons connectivity in individuals with major depressive disorder, associated with severity of psychological symptoms. The pons interacts with the amygdala to process sad affective information, suggesting a potential therapeutic target for mood regulation.
A new AI-powered mental health application, FuturSelf, uses machine learning to identify the shortest path to mental stability. The system offers personalized recommendations for improving long-term well-being.
New research from King's College London found that members of the British Armed Forces who were physically injured while fighting in Afghanistan are more likely to experience poor mental health, including depression and PTSD. The study also suggests that the type of injury sustained can influence the overall outcome.
A new study found that 64% of adults who had contact with the child welfare system as children achieve excellent mental health, highlighting resilience and factors associated with flourishing. Chronic pain, major depression, and social isolation hinder optimal mental health.
A new study suggests that losing a grandmother may have a significant impact on adolescent boys, leading to a 50% increase in depressive symptoms. The researchers also found that the loss of a grandparent can be a risk factor for teen depression and other negative outcomes.
A UC Davis Health study found that patients on stable but higher-dose opioid therapy who had their doses tapered by at least 15% had significantly higher rates of overdose and mental health crisis in the second year after tapering compared to their pre-tapering period. The risks were greatest in patients with the highest baseline doses.
A study by researchers from the University of Basel found that probiotics can improve depressive symptoms in patients taking antidepressants. The probiotic group showed a greater improvement in symptoms than the placebo group, with changes in intestinal flora composition and brain activity when viewing emotional stimuli.
A workplace mental health program significantly reduced employees' symptoms of depression and anxiety, allowing them to stay in the workforce. Employers also saw a positive financial return on investment from the program.
A recent Binghamton University study found that women experience reduced stress levels on weekends due to increased downtime. The research also discovered that physically fit individuals relax faster and can benefit from incorporating physical activity into their daily routine.
A recent study has found that prolonged use of videoconferencing for work, known as 'Zoom fatigue,' is associated with increased levels of loneliness, depression, and even food insecurity. The researchers concluded that employers and employees should consider the impact of videoconferencing on mental health and productivity.
Research found that stimulating a specific brain circuit relieves pain and reduces defensive behaviors in rats, indicating potential physical and psychological relief. The pathway also increases reward and feeding behavior, suggesting improved emotional state.
A new study has found that people who believe in COVID-19 conspiracy theories are more likely to experience severe anxiety and depression. The research, published in Frontiers in Psychiatry, used a scale to measure belief in conspiracy theories and found a significant correlation with increased symptoms of anxiety and depression.
A new study finds that women using hormonal contraceptives have lower rates of attempted suicides compared to those who do not use them. The research, published by the European Psychiatric Association, analyzed data from over 587,000 Finnish women and found a significant reduction in suicide attempts among hormonal contraceptive users.
A new study from Keck Medicine of USC shows that patients with IBD are nine times more likely to develop depression than the general population, while those with depression are twice as likely to develop IBD. Siblings without either condition are also at increased risk.