Scientists at Salk Institute find protein CCN1, secreted by astrocytes, maintains stable neural circuits in adult brains. The discovery could lead to new therapeutics for brain injury and stroke.
A University of Sydney-led study found that 42% of Australian adults experienced traumatic events as children, leading to a 50% higher risk of developing mental health or substance use disorders. Childhood trauma is linked to chronic physical health conditions and can have lifelong consequences.
A recent study published by the American Psychological Association found that about a quarter of U.S. service members and veterans who start psychotherapy for post-traumatic stress disorder (PTSD) quit before finishing treatment. The study analyzed 181 studies covering over 124,000 military participants and discovered significant diffe...
A University of East Anglia study found that trauma-focused CBT significantly improved PTSD symptoms, anxiety, depression, and emotion regulation in children with multiple traumas. The therapy was effective and safe, even for those with complex and severe symptoms.
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Researchers at the Institute for Basic Science have discovered that excessive GABA produced by astrocytes impairs fear extinction in PTSD. A new brain-permeable drug called KDS2010 has reversed PTSD-like symptoms in mice, providing a promising therapeutic approach.
A new study confirms that the Bergen 4-Day Treatment (B4DT) is effective in treating panic disorder, with patients reporting significant improvement weeks after treatment. Long-term follow-up studies show that the treatment's benefits persist and even increase over time, reducing symptoms of anxiety and depression.
A study of nearly 11,000 individuals found that men with panic disorder are more vulnerable to developing problematic drinking behaviors than women, potentially due to self-medication. The research highlights the need for sex-specific assessment and intervention strategies in treating comorbid conditions
Researchers at the Salk Institute identified a specific brain circuit responsible for slowing anxious breathing, connecting the frontal cortex to the brainstem. This discovery may offer a scientific explanation for the beneficial effects of practices like yoga and mindfulness on alleviating negative emotions and could lead to the devel...
Researchers found that prenatal exposure to synthetic cannabinoid led to cardiovascular problems in female rats and increased respiratory sensitivity to carbon dioxide in male rats. Sleep quality also deteriorated in both sexes, with males experiencing sleep fragmentation due to frequent wakefulness episodes.
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The latest APA journal issues explore schizophrenia spectrum disorders, PTSD treatment, and college mental health. Research highlights include new approaches to psychosis treatment and findings on mental health in higher education.
Salk researchers created tools to study neuropeptides, finding they control the brain's fear response in mice. Neuropeptides are released during a mild stimulus, triggering fear behaviors, which can be reduced by silencing their release.
Researchers have discovered a brain circuit that mediates panic disorder, consisting of specialized neurons that send and receive the neuropeptide PACAP. Inhibiting PACAP signaling reduces panic symptoms, offering promising findings for future treatments.
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A study published in Psychological Medicine found that the widely prescribed sedative alprazolam XR may be less effective than believed, with publication bias inflating its efficacy by over 40%. This suggests caution for patients and clinicians starting a prescription for panic disorder.
A community-engaged approach to research prioritizes the concerns of participating communities, leading to a better reflection of community needs and issues. By incorporating CBPR, researchers can minimize biases and increase public trust in science.
A new study found that dogs can differentiate between breath and sweat samples from people before and after a stress-inducing task with an accuracy of 93.75%. The researchers believe that dogs are able to detect changes in volatile organic compounds produced by humans in response to stress.
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Research reveals mental illness disrupts autonomic functions, leading to greater blood pressure variations during the day. People with mental health issues often experience reduced heart rate variation, indicating poor stress response and exacerbating chronic stress effects.
A new VA study finds a strong connection between PTSD symptom severity and anxiety sensitivity among female Veterans who experienced military sexual trauma. Treating anxiety may ease core PTSD symptoms, suggesting anxiety sensitivity as a potential target for treatment.
Researchers found that people with mental health disorders experience brain activity differently when sensing internal bodily conditions. The dorsal mid-insula region showed distinct activity patterns across various disorders, including depression, anxiety, and eating disorders.
A computerized brain implant effectively relieves short-term and chronic pain in rodents, detecting brain activity linked to pain and triggering therapeutic stimulation of the prefrontal cortex. The device reduces pain intensity and is less likely to cause addiction, offering a promising new strategy for pain therapy.
A large-scale study from Lund University found that psychotherapy for panic disorder produces lasting improvements in symptoms and quality of life. Two years after treatment, 70% of patients were clearly improved and 45% were remitted.
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A study by Alexa Barrett and Al Kopak found that male detainees with PTSD, PD, and AUD were more likely to commit violent offenses. The combination of these conditions significantly increased the likelihood of violence.
A recent study has found that chronic stress can lead to changes in the mitochondria of brain cells, which may contribute to anxiety symptoms. Researchers identified differences in mitochondrial pathways between stressed and non-stressed mice and patients with panic disorder.
A 18-year study of thousands of Americans found that people who persist in their goals and have a positive outlook tend to experience less depression, anxiety, and panic attacks. The study suggests that perseverance and optimism can create resilience against mental health disorders.
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Researchers at the University of Cincinnati have discovered a link between acid-sensing receptor TDAG8 and panic disorder symptoms. The study found significantly increased levels of TDAG8 in patients with panic disorder, correlating with symptom severity and treatment response.
Researchers investigated whether easily identifiable patient characteristics can improve treatment outcomes for panic disorders. They found correlations between longer illness duration and lower response rates to venlafaxine XR, higher age and increased side effects with paroxetine, and longer treatment durations and improved response ...
A new diagnostic model, Hierarchical Taxonomy of Psychopathology (HiTOP), has been proposed to address fundamental flaws in the current DSM-5 model. HiTOP allows for a continuous, dimensional assessment of psychopathology, enabling more personalized treatment and recognition of significant problems.
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Patients taking antidepressants for depression are more likely to report gastrointestinal and cardiovascular side effects if they also have panic disorder, according to a new study. Co-occurring panic disorder is associated with an increased risk of worsening depressive symptoms.
Researchers found that increased sensitivity to uncertain threat is a common trait among anxiety disorders, including panic disorder and social anxiety disorder. This finding could lead to more impactful and efficient treatment approaches by targeting shared neurobiological characteristics.
A large national survey found nearly 10% of Americans have lifetime drug use disorder diagnoses, resulting in significant impairment and comorbidities. The study also highlights the importance of treatment, with only 24.6% of those with lifetime diagnoses receiving treatment.
A new spectrum disorder called ALPIM syndrome has been identified by researchers, which links anxiety to physical disorders. The study found a high correlation between panic disorder and four domains of physical illness, including joint laxity, fibromyalgia, and immune disorders.
Research identifies ASIC1a gene variants associated with panic disorder and respiratory symptoms such as shortness of breath and feelings of suffocation. The study found that the genes are also linked to amygdala structure and function, raising hopes for new treatments.
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A study published at the ECNP congress found that individuals with photophobia (fear of bright light) experience medium to high levels of aversion to bright light. The research suggests a possible association between photophobia and panic disorder, but further studies are needed to confirm this relationship.
A new study from Johns Hopkins Bloomberg School of Public Health reveals substantial discrepancies among mid-life and late-life adults in reporting past mental health disorders compared to physical disorders. The study found that lifetime estimates of mental disorders ascertained by retrospective versus cumulative evaluations were sign...
Scientists at EMBL discovered that different brain regions handle various fears, with mice displaying distinct brain activity responses to threats from same-species and predator species. This finding could lead to targeted treatments for specific phobias and panic attacks in humans.
Researchers found that sleep deprivation triggers excessive anticipatory anxiety by activating the amygdala and insular cortex. Innate worriers are more vulnerable to this impact, suggesting that sleep therapy could be a potential treatment for anxiety disorders.
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Researchers have identified multiple brain regions responsible for generating fear and panic, including the amygdala, brainstem, diencephalon, and insular cortex. The findings suggest that an intact amygdala normally inhibits panic, and its absence can lead to anxiety-related conditions.
Researchers found that a combination of cognitive-behavioral therapy with a transdiagnostic approach significantly improved anxiety disorders such as fear of flying and public speaking. This approach treats patients with one set of principles across all types of anxiety disorders, leading to considerable improvement in comorbid diagnoses.
A new study found that individuals with mood and anxiety disorders are more likely to abuse opioids. Non-medical prescription opioid use was associated with an increased risk of developing any mood disorder, major depressive disorder, bipolar disorder, and all anxiety disorders. Early identification and treatment of mood and anxiety di...
Rescue and recovery workers suffered high rates of asthma, sinusitis, and gastroesophageal reflux disease (GERD) due to inhalation of toxic dust. The study also found a significant burden of depression, post-traumatic stress disorder (PTSD), and panic disorder among these workers.
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Panic attack sufferers experience significant physiological instability for at least 60 minutes before the attack, including changes in heart rate, respiration, and carbon dioxide levels. This finding challenges the common notion of sudden, unexpected panic attacks.
A recent study published in Psychosomatic Medicine found that individuals with high anxiety sensitivity exhibited reduced anxiety reactivity when engaging in high levels of physical activity. Regular exercise was shown to be an effective alternative or complementary strategy to traditional treatments for depression and anxiety problems.
A study by Brown University researchers found that certain stressful life events cause panic symptoms to increase steadily over succeeding months, rather than acutely. This challenges the common assumption that stress triggers immediate panic attacks.
Researchers found that four microRNAs (miR-22, miR-138-2, miR-148a, and miR-488) are associated with panic disorder, regulating genes related to anxiety pathways in the brain. The study suggests a coordinated involvement of multiple risk genes, implying the existence of molecular 'switches' that control gene function.
A new breathing therapy, CART, has been shown to be more effective than traditional cognitive therapy in reducing panic symptoms by reversing hyperventilation. The treatment program teaches patients to breathe normally, reducing chronic and acute hyperventilation and associated physical symptoms.
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A new online treatment system using biofeedback therapy and web technologies aims to improve patient care for individuals suffering from panic disorder. The system, developed by researchers in Taiwan, has shown promising results in reducing panic attacks and improving symptoms.
A nationally representative survey found that about 13% of American children and teenagers have a mental disorder, with lower socioeconomic status linked to higher rates. Mental health services are often underutilized, particularly among minority youth, highlighting the need for increased access and support.
A study found that individuals diagnosed with panic attacks or disorder have a significantly increased risk of developing coronary heart disease and suffering a heart attack, particularly among those under 50 years old. However, the research also showed that people with panic disorders face a reduced risk of dying from heart conditions.
A study of 404,654 people found that those diagnosed with panic attacks were more likely to develop coronary heart disease (CHD) and suffer a heart attack, particularly in younger individuals. However, the risk of dying from CHD was reduced among all age groups who had been diagnosed with panic attacks.
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A meta-analysis of D-cycloserine and fear extinction found that the medication improves the effectiveness of behavioral therapy for anxiety disorders. Tolerance may develop to its effects, suggesting it should be used before therapy sessions to enhance brain responsiveness.
A new NIH study identifies high incidence rates of substance use disorders and major mood and anxiety disorders in the US population. The study found that age is a critical general risk factor for first onset DSM-IV substance use, mood, and anxiety disorders.
A Florida State University professor is developing a new approach to help smokers with anxiety disorders quit. The study focuses on reducing anxiety sensitivity, which is a risk factor for developing anxiety problems.
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A study found that carbon dioxide inhalation triggers emotional distress and a panic response in healthy volunteers. The reaction is dose-dependent, with higher CO2 concentrations causing stronger negative emotions. Older subjects exhibited a weaker reaction, suggesting an underlying protective brain alarm may be blunted in the elderly.
A study of 3,369 postmenopausal women found that those who experienced at least one full-blown panic attack had a four times higher risk of heart attack and nearly twice the risk of death from any cause. The findings suggest that panic attacks may be an independent risk factor for cardiovascular events.
Scientists identified how brain responds to an approaching menace, shifting from strategic areas to reactive responses. The study found that the closer a threat gets, the more impulsive the response, reducing free will.
Researchers at the University of Illinois found that brain activity patterns differ between two types of anxiety: anxious apprehension (verbal rumination, worry) and anxious arousal (intense fear, panic). The study used fMRI to identify distinct brain regions active in each type of anxiety.
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A recent study by Columbia University's Mailman School of Public Health reveals that nearly 22% of pregnant U.S. women smoke cigarettes, with a significant association between smoking and mental disorders among pregnant women.
Researchers at the University of Iowa have discovered a link between genetic information in white blood cells and mental health conditions like panic disorder. The study found distinct patterns of gene expression in individuals with and without panic disorder, which could lead to new diagnostic tools and therapies.
A study by Group Health found that panic episodes in diabetic patients are linked to poorer health outcomes, including higher blood sugar levels and greater disability. The researchers also discovered that half of the patients with panic also had major depression.
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A new FSU study reveals that individuals with high anxiety sensitivity are more likely to develop a clinical case of anxiety or panic disorder. This link was established through a two-year follow-up study involving 404 young adults, indicating anxiety sensitivity as a risk factor for anxiety disorders.
Panic disorder affects up to 5% of the population, causing recurrent anxiety attacks and agoraphobia. Anti-depressants and cognitive-behavioural therapy (CBT) are effective treatments, but less than half of those in need receive care due to barriers such as diagnosis difficulties and insurance coverage issues.