The new technique, 3D optical coherence refraction tomography (3D OCRT), produces highly detailed images revealing features difficult to observe with traditional OCT. It has the potential for biomedical research and eventually more accurate medical diagnostic imaging.
Researchers have identified an anti-malarial compound, ML901, that inhibits the malaria parasite without harming mammalian cells. The compound works by hijacking a reaction to make the parasite self-destruct, showing rapid and prolonged action against resistant strains.
Researchers emphasize the need for targeted recruitment to make genetic tests clinically useful for non-European groups. By addressing cultural concerns and underrepresentation, efforts can reduce the incidence of variants of uncertain significance (VUS) in genetic databases.
Researchers uncover distinct metabolic defect in malnutrition-related diabetes, differing from type 1 and 2 diabetes. The condition affects tens of millions, mostly thin and impoverished adolescents and young adults, with limited treatment options available.
Researchers found five sites on the oxytocin and vasotocin receptors where modern humans are unique compared to archaic humans and non-human primates, affecting social behaviors such as autism and aggression. These variants are highly functional and active in brain regions involved in social cognition.
A recent study examined rates of experiencing and perpetrating sexual violence among nearly 4,200 youth aged 14-16. The research found significant differences in rates of violence based on gender identity. Younger and more marginalized individuals were disproportionately affected by both victimization and perpetration of sexual violence.
Researchers at Massachusetts General Hospital developed scission-accelerated fluorophore exchange (SAFE) to visualize molecules in living cells without disrupting normal physiological processes. The method uses immunofluorescence tags and fast chemical reactions to remove tags, creating a multi-color movie-like continuous stream of ima...
The NIH has launched a clinical trial testing dupilumab, an approved treatment for moderate-to-severe asthma, in children with poorly controlled allergic asthma living in low-income urban neighborhoods. The study aims to define the activity levels of gene networks associated with asthma attacks and improve lung function.
A meta-analysis by Dr. Maggi Price and colleagues found that Black youth living in communities with high levels of anti-Black racism are less likely to benefit from psychotherapy. The study suggests that addressing stigma and incorporating advocacy into treatment is crucial for improving mental health outcomes. Training programs must e...
Researchers used drone data to analyze vegetation indicators, such as color appearances, to predict southern rust outbreaks. The study revealed a positive correlation between the presence of southern rust at grain-filling time and yield, enabling informed decision making for growers.
A new report confirms the benefits of supplements containing lutein and zeaxanthin for slowing age-related macular degeneration progression. The AREDS2 study found that these supplements reduced the risk of AMD progression by 26% compared to the original formula, which contained beta-carotene.
A recent study at UC San Francisco discovered that fragmented tau protein in diseased neurons could be a new target for existing drugs, potentially improving diagnosis and treatment of Alzheimer's. The researchers found that measuring the fragments in cerebrospinal fluid may help distinguish between different forms of dementia.
A study of over 12 million emergency department visits reveals significant racial and ethnic disparities in imaging rates among children. Non-Hispanic white patients consistently received more diagnostic imaging than their black counterparts, highlighting systemic inequities in healthcare.
Researchers successfully created a two-body time-crystal system in an experiment that challenges our understanding of physics. They also found that time crystals can be used to build useful devices at room temperature, opening up new possibilities for quantum computing.
A recent study published in Nature Medicine predicts that China's abandonment of Zero-COVID policies could result in approximately 1.5 million deaths due to the highly contagious omicron variant of COVID-19. The study highlights the need for critical measures such as vaccination, antiviral therapies, and non-pharmaceutical intervention...
A study published in PLOS Medicine found that children exposed to road traffic noise in schools have slower attention and working memory development compared to those in quieter environments. The research suggests potential implications for environmental noise policies protecting school environments.
Recent papers in ACS Environmental Au explore the impact of aerosol acidity in the southeastern U.S. and the effects of environmental films on native ecosystems. The journal also investigates electrospun nanofibrous membranes for controlling airborne viruses.
Neuroscientists demonstrate that mice can learn to suppress their innate escape response, effectively ignoring stimuli deemed non-threatening. The study's findings show that this suppression is specific to the stimulus and dependent on recent threat-escape history.
In a mouse model, stromal cells developed before weaning age promote the maturation of the intestinal barrier by forming a specialized niche. Absence of these cells induces defect in postnatal growth and increases susceptibility to intestinal inflammatory diseases.
Researchers found that exercise increased levels of adrenalin, reprogramming the immune system to recognize and attack cancer cells. This led to a 50% reduction in cancer formation and 25% decrease in tumor weight in mouse models. In human patients, exercising before surgery also improved overall survival rates.
A new study finds that cancer patients are at a greater risk of developing diabetes, particularly those with lung, pancreatic, breast, brain, urinary tract, or uterine cancers. The study also shows that cancer patients who develop diabetes die sooner than survivors without diabetes.
Researchers suggest that giraffes' unique head and neck morphologies were adapted for fierce head-butting behavior in competition for mates. The discovery of ancient fossils reveals a complex evolution driven by both food competition and sexual selection.
Researchers at The University of Queensland have discovered a method to date calcite trapped in ancient ocean floors, which could aid in sourcing critical minerals for electric cars and solar panels. This breakthrough could help meet the growing demand for renewable energy technologies.
Researchers found that personal narratives increase empathy and encourage prosocial behaviors, particularly towards higher-risk groups like the incarcerated or healthcare workers. The study suggests using storytelling can shift an individual's perspective and promote behavioral changes in public health interventions.
Researchers developed highly efficient pure green-emitting InP-based QLEDs with an external quantum efficiency of 15.2%. The performance can be optimized by regulating the components of the inner alloyed ZnSe shell, reducing surface defects and increasing photoluminescence quantum yield.
Researchers have identified new biomarkers to detect non-small cell lung cancer in its early stages through a blood test, offering improved survival chances. The approach can also identify potential drug resistance, allowing clinicians to choose alternative treatment options.
A RAND Corporation survey found that fewer than half of public health officials expressed confidence in their jurisdiction's preparedness for the 988 mental health hotline. The survey revealed gaps in strategic planning, financing, infrastructure, and service coordination.
A study by Dr. Anja Weidenmüller reveals that glyphosate affects the collective thermoregulatory capacity of bumblebee colonies, impacting brood development and colony growth. This effect is particularly pronounced in times of resource scarcity, highlighting the need to reassess pesticide approval procedures.
The DAVINCI mission will descend through Venus' layered atmosphere to the surface, measuring critical aspects of the planet's climate system. The probe will acquire high-resolution images and detailed chemistry measurements of the atmosphere and surface.
A University of Queensland-led study found that millions of COVID-19 patients may have undiagnosed acute kidney injury (AKI), which can lead to serious illness or death. The true AKI diagnosis rates are likely double existing data, highlighting the need for improved detection and management strategies.
Researchers have discovered a novel chemical reaction that allows for the efficient migration of molecular fragments, enabling the production of health-promoting ingredients in food. This groundbreaking discovery has the potential to revolutionize the field of chemistry.
A recent study published in Kidney International Reports reveals that consuming at least one cup of coffee per day may reduce the risk of acute kidney injury (AKI) by 15%. The largest reductions were observed in individuals who drank two to three cups of coffee daily, with a 22% lower risk.
A team of researchers at The University of Texas at Austin has developed components that will allow future devices to achieve increased speeds necessary for 6G. The new radio frequency switches are made of two-dimensional materials, taking significantly less energy to operate, and can provide low-energy, high-speed functions.
A randomized clinical trial found that smokers who received cigarette packs with graphic warning labels hid their packs 38% more often. However, when they returned to regular packs without the labels, hiding behavior returned to baseline levels. The study suggests that graphic warnings may not be effective in reducing smoking behavior.
Researchers found that tobacco hawkmoths can identify vital nectar sources and suitable host plants despite a complex odor mixture, with female moths responding strongly to specific floral scents after mating. The study suggests that plant-typical mixing ratios play a crucial role in guiding the moths to the right oviposition sites.
Researchers discovered a massive protostellar disk in the Galactic Center with spiral arms, challenging previous understanding of star formation. The disk was perturbed by a close encounter with a nearby object, leading to the formation of spiral arms through accretion disk dynamics.
Researchers have identified 30 COVID-19 patient antibodies that can neutralize a variety of coronaviruses, including SARS-CoV-1 and bat coronaviruses. These broadly neutralizing antibodies may lead to the development of next-generation coronavirus vaccines offering broader protection.
Researchers found that neuronal damage in Alzheimer's disease originates from within brain cells' lysosomes, where amyloid beta appears. This discovery could explain why drugs designed to remove amyloid deposits have failed to stop the disease.
A new study presents a self-powering smart pillow that tracks head movement during sleep using triboelectric nanogenerators. This system could improve the accuracy of sleep monitoring and have uses beyond tracking sleep, such as monitoring patients with cervical spondylosis or detecting early warning signs for falls.
Researchers applied machine learning to MRI brain scans and found that autism does not cluster into distinct subtypes but rather exists as continuous variation in brain structure. The study's findings suggest that dimensional approaches can provide a better account of individual variation than discrete diagnostic categories.
A new fossil discovery solves the giraffe evolutionary mystery by revealing that long necks evolved as a weapon in male courtship competition. The unique characteristics of the fossil, including its disc-like ossicone and complex joints, suggest an extreme adaptation for high-speed head-to-head impact.
A study by Cedars-Sinai researchers confirms that counting metastatic lymph nodes is a dominant predictor of cancer death, improving staging and treatment for solid tumors. The simple process can be applied in virtually all medical settings without increased cost or complexity.
A study found that Brazil's Salmonella vaccine for poultry contributed to the emergence of antibiotic-resistant strains. However, these resistant bacteria have not increased food poisoning cases in humans in the UK.
A new study found that 68% of COVID-19 deaths were adults in low socioeconomic positions working in labor, service, and retail jobs. The study confirms associations between mortality rates and socioeconomic position, gender, ethnicity, and race.
Researchers have elucidated principles of human brain organisation across visual, auditory, somatosensory, and motor functional systems. The study revealed systematic changes in receptor architecture and gene expression within each system, reflecting increasing complexity of information processing.
A new research proposes a cloud model-based LDoS attack detection method with lower false positive and false negative rates, verified through NS2 simulation platform testing
Researchers have developed a rigorous computer simulation technique to optimize LNG tank design, reducing construction costs while improving safety against catastrophic failures. The new model can be used to mitigate environmental and economic consequences of failure, enabling Australia to store more energy at the right time.
Researchers at Chalmers University of Technology have developed a method to make shipping industry significantly greener by using hydrofoils to reduce water resistance. The new technology can increase the range of electric vessels and reduce fuel consumption by up to 80%.
Researchers at Karolinska Institutet have identified a new vaccine candidate based on nano-sized membrane vesicles that provide protection against multiple pneumococcal strains. The vaccine target two conserved lipoproteins MalX and PrsA, showing serotype-independent cross-protection.
Exposure to glyphosate herbicide impairs bumblebees' ability to maintain hive temperature, particularly during food scarcity. The study found a 25% decrease in collective thermoregulation capacity, suggesting a hidden cost of glyphosate use on already vulnerable pollinator species.
Bacteria's CRISPR system uses spacers to store viral information, but must balance risk of autoimmunity with immune memory. Longer spacers reduce autoimmune response risk, allowing more spacers to be stored without triggering an immune reaction.
A new study reveals that combinations of multiple genetic factors determine the risk and severity of symptoms in Autism Spectrum Disorder. Researchers analyzed 37,375 individuals from 11,213 families to understand how rare mutations and common genetic variation contribute to ASD.
Scientists propose a new classification scheme using the Beaumont number to describe whether mountain elevation is controlled by weathering and erosion or properties of the Earth's crust. The study resolves a long-standing question about the controlling factors of mountain growth, finding that it depends on geographic location, climate...
Researchers found that unpredictable parental behaviors disrupt optimal brain circuit formation in children, leading to increased vulnerability to mental illness and substance abuse. Studies using mice and human infants suggest that predictable signals and environments are crucial for healthy brain development.
A study published in PLoS Medicine found that traffic noise at schools is detrimental to working memory and attention in primary-school students. Children attending schools with higher levels of traffic noise showed slower cognitive development, with a 5 dB increase resulting in a 11.4% slower development rate.
A new study suggests China's ability to peak its carbon emissions by 2030 is tied to the country's economic growth rate. To achieve this goal, China must develop non-fossil energy sources rapidly.
A team led by University of Utah Health has improved the quality and consistency of care in emergency situations in Rwanda. The project, which began a decade ago, provided advanced training for emergency responders and hospital staff and established standardized checklists for patient care.
The study discovered that cyclic hypertensive pressure stimulation and matrix compliance regulate vascular smooth muscle cell phenotypic switch, leading to intimal thickening and early atherosclerosis progression. Cofilin is identified as the key regulator in this process.
A new study suggests achieving a 50% reduction in US greenhouse gas emissions by 2030 is possible through increasing renewable capacity and transitioning to electric vehicles. This would limit global warming to 1.5 degrees Celsius, aligning with the UN's climate target.
Debilitating snare injuries in female spotted hyenas of the Serengeti delayed their age at first reproduction and reduced litter size, while also decreasing offspring survival rates. This long-term decrease in reproductive performance may result from increased inflammatory and immune responses to snare injuries.