A new study found a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia. Individuals with long COVID face significantly higher rates of these disorders, alongside worse mental health and quality of life.
Bloomsbury is introducing Altmetric Explorer to track social attention and sharing of its publications, providing insights into reach, impact, and value. The tool will inform future editorial strategy and improve reader engagement.
A large-scale study found that zoos are often breeding endangered animals in skewed sex ratios, which can limit genetic diversity and increase the risk of extinction. The research highlights the need for zoos to collaborate and share data on their animal populations to manage conservation efforts effectively.
Researchers found that people who experienced malnutrition early in life may have survived threats like plague at greater rates until young adulthood. However, this survival advantage could drop significantly when entering middle and late adult years.
Long-term heat exposure negatively impacts students' cumulative learning, with complex tasks more affected than simpler ones. Lower socioeconomic groups face disproportionately greater impacts, underlining critical inequalities.
At ESC Congress 2025, over 40 pivotal studies will be presented, addressing major clinical questions and unmet needs in global cardiovascular care. The trials focus on innovative treatments for conditions like chronic Chagas cardiomyopathy and hypertrophic cardiomyopathy.
Recent scientific advances aim to enhance the efficacy of psychosocial treatments for mood and psychotic disorders, according to Dr. Marc J. Weintraub's upcoming webinar. Innovative approaches discussed include a mobile app adjunct therapy for adolescents at risk and psilocybin integration for adults with major depression.
Researchers discovered that cancer cells have a defensive mechanism to repair DNA damage and survive physical stress by activating mitochondria to pump in extra ATP. This finding could lead to new therapeutic approaches by targeting the mechanism's underlying scaffold.
A study found that users who exchanged daily walking steps for digital train tickets increased their walking by an average of 626.2 steps/day. Those using shopping coupon incentives walked 715.2 steps/day more on average than non-users. The results suggest effective promotion of active travel through well-designed mHealth apps.
The Brain & Behavior Research Foundation recognizes Joseph J. Taylor, Ash, and Harnett as recipients of the 2025 Klerman and Freedman Prizes for their outstanding work in mental illness research. Long Li receives the Freedman Prize for his basic research contributions to understanding depression and PTSD.
The new book highlights the transformative role of artificial intelligence (AI) and machine learning (ML) across various domains, including mechatronics, cybersecurity, digital health, and automation. Readers will gain practical insights into AI-based techniques in power systems, social media management, and healthcare diagnostics.
A recent study by UCLA researchers found that introducing new genetic variation from Texas reduced the influence of harmful mutations in Florida panthers, improving their fitness. However, the effect of this intervention may be temporary, and continued protection is needed to preserve the subspecies.
A team of astronomers captured a detailed image of a ribbon-like jet emerging from the heart of OJ 287, revealing extreme energy and motion near the black hole. The study sheds new light on supermassive black holes and their powerful jets, potentially offering clues to binary black hole mergers.
This book presents innovative nanomaterials for efficient pollutant removal from wastewater, reducing energy consumption and promoting eco-friendly treatment outcomes. It explores emerging trends and future directions in nanotechnology-based purification, providing practical insights for researchers and professionals.
A new study shows that delivering a single injection of gene therapy at birth may offer years-long protection against HIV. The treatment uses an adeno-associated virus to deliver instructions to muscle cells, which produce broadly neutralizing antibodies capable of neutralizing multiple strains of HIV.
Researchers from Trinity College Dublin develop a method to harness structural colour using microfabrication technique, enabling ultra-sensitive materials for environmental sensing and biomedical diagnostics. The breakthrough also paves the way for next-generation medical sensors that can track biochemical changes in real-time.
A UNLV study uses an mRNA cocktail to selectively route to the pancreas, reducing the risk of immune responses and side effects. The breakthrough offers new hope for treating pancreas-related diseases, including cancer and diabetes.
A team of researchers at Kyoto University has successfully developed a method to calculate the vibrations of black holes using exact WKB analysis. The approach reveals complex patterns in spiraling waves, enabling precise capture of frequency structure and bridging theoretical predictions with observational data.
A large-scale genetic study found ten new regions associated with the ability to detect specific odours, with three showing sex-specific effects. The research also uncovered a link between the risk of Alzheimer's disease and the sense of smell, highlighting the interconnectedness of these senses.
The EnIGMA framework demonstrates superior performance across multiple benchmarks, solving more than three times as many cybersecurity challenges as previous AI agents. The research also identifies a previously unknown phenomenon called 'soliloquizing,' where the AI model generates hallucinated observations.
A study in the Canadian Journal of Cardiology finds that delaying chest compressions to prevent tongue swallowing can lead to poor outcomes, including death or severe brain injury. The research exposes media-fueled misconceptions and emphasizes the importance of immediate CPR training.
Reinforcement learning world models are introduced as a promising tool for modeling complex atomic level changes in catalyst surfaces. The review presents advancements in using Dreamer-based architectures and multi-objective optimization strategies to address long-standing challenges in catalytic surface modeling.
Scientists generate collective molecular vibrations in a liquid by placing an electron ultrafast. These vibrations govern the electric behavior of the liquid and can be tuned to adapt its properties. The study reveals new insights into polar liquids' dynamics.
This article reviews bronchiectasis phenotypes and endotypes, exploring their impact on disease management and treatment strategies. Recent research has identified distinct inflammatory endotypes, guiding targeted therapies and improving patient outcomes through personalized approaches.
A recent study published in New Phytologist reveals a crucial gene necessary for plant reproductive structures. The gene, named SHOT GLASS, is found to regulate the development of air chambers and sexual organs in liverworts, a model organism for studying plant reproduction.
The Fibrosens project aims to develop a novel platform for real-time monitoring of fibrosis biomarkers in muscular dystrophies using nanoplasmonic sensors. The project will enable faster and cheaper testing of anti-fibrotic drug candidates, as well as personalized drug screenings for patients with specific mutations.
A recent study by Drexel University researchers analyzed 24 coastal New Jersey communities' communication of climate-related hazards. The analysis found wide variation in the number and extent of mitigation actions taken, with stormwater management and road improvements being the most frequently mentioned projects.
Researchers discovered that Candida albicans can persist in the mouse gut for at least 58 days without causing harm, and treatment with anti-fungal medication only reduced its presence. The fungus's ability to colonize was linked to the production of candidalysin and adhesins.
A multicenter study found influenza-associated acute necrotizing encephalopathy (ANE) carries a high risk of morbidity and mortality in children, with a 27% mortality rate. Survivors often experience neurological difficulties, emphasizing the need for rapid treatment and vaccination to prevent ANE.
Researchers developed an open-source software tool, Phoenix, to simulate light behavior in quantum systems, solving wave equations in record time without high-performance computing expertise. The program is up to a thousand times faster and 99.8% more energy-efficient than conventional tools.
This study uses AI to pinpoint optimal synergies in combination therapies, slashing experimental costs and accelerating discovery by up to 7.2% in accuracy.
Researchers found that high rates of coronary heart disease were linked to poverty, limited healthcare provider availability, and low broadband access. However, some counties with similar challenges reported lower-than-expected cardiovascular outcomes, suggesting the need for tailored strategies to address health disparities.
Cancer-associated fibroblasts (CAFs) exhibit paradoxical effects on immunotherapy, sometimes hindering and other times helping to control tumors. Research identifies specific CAF subtypes that enhance or suppress immune cells, offering promising targets for therapies.
A new study by Mass General Brigham found that states with flavored e-cigarette ban policies experienced a significant decline in e-cigarette use among young adults and adults, but a slower decrease in cigarette smoking rates. This mixed impact raises concerns about the unintended consequences of flavor bans.
Researchers from Japan studied DJ-1's catalytic mechanism, revealing key amino acids involved in cPGA hydrolysis. Mutations in these residues revoked cPGA hydrolase activity, confirming the pathophysiological implications of DJ-1.
A new AI-based technology analyzes mammograms to predict a woman's five-year breast cancer risk, outperforming standard methods by 2.2 times. The system provides an absolute risk score comparable to national incidence rates, enabling targeted prevention and early detection.
A $5.5 million federal grant will support clinical trials to treat fragile X-associated tremor/ataxia syndrome (FXTAS). The project aims to develop accurate outcome measures for future trials, ensuring patients and caregivers have a say in what matters most.
Researchers found that solar energy delivers the biggest climate payoff in certain US regions, with California and Florida seeing significant CO2 reductions. A 15% increase in solar power led to a reduction of up to 147.18 metric tons of CO2 in California alone.
Researchers have found electrolytes with boron additives can mitigate critical challenges of lithium metal batteries, including lithium dendrite formation and low Coulombic efficiency. The boron additives also improve the specific discharge capacity and high-rate performance of lithium-ion batteries.
Researchers from Italy developed a conductive biopaste to accelerate coral growth and a natural healing patch to target antibiotic delivery to diseased corals, both showing promising results in laboratory tests.
A study published in the Royal Society's Proceedings B found that closely related bat and bird species share the same habitat due to their shared evolutionary history. This challenges previous ideas about competition driving species apart, suggesting that animals with similar needs tend to group together in suitable habitats.
A new study reveals that a slowdown in the Atlantic Ocean current could halve annual precipitation in tropical regions, drying out rainforests and upending ecosystems. Climate change is predicted to weaken the current, leading to significant reductions in rainfall over Central America, the Amazon, and West Africa.
Researchers at the University of Basel have developed an engineered enzyme to precisely build complex molecules, such as pharmaceuticals and fine chemicals. The new approach uses metal hydride hydrogen atom transfer (MHAT) chemistry with enzymatic catalysis to produce three-dimensional molecules with single-handed configuration.
The CPADS web tool integrates data from GEO, TCGA, and GDSC databases to analyze gene expression changes, correlations between genes or drugs, and pathway enrichment in cancer samples. L1CAM was identified as a potential drug resistance target in non-small cell lung cancer through CPADS analysis.
The FDA has authorized artificial intelligence devices for Alzheimer's and related dementias despite limited demographic data. Disease status, age, sex, and race were reported for fewer than half of devices, raising concerns about real-world generalizability.
Researchers find large language models (LLMs) can predict drug-target interactions more accurately. LLMs are advancing drug discovery by optimizing molecule design and improving model reliability.
A Stanford Medicine-led report found that children with rare flu complications like influenza-associated acute necrotizing encephalopathy (ANE) need prompt treatment to survive. The condition causes brain swelling and a runaway immune response, leading to fatal outcomes if left untreated.
Researchers have developed a three-dimensional imaging method to distinguish between two fundamental processes by which light is transformed into electric current in quantum materials. The breakthrough could lead to improvements in solar energy systems and optical communications technology.
This book presents cutting-edge approaches to combat cancer, including exosomal delivery systems, CRISPR/Cas9 gene editing, and immunotoxin therapy. Natural compounds are also examined for their anticancer potential.
A cohort study found that stroke center certification decreases racial disparities in treatment for white patients within the same hospital, but such disparities remain for Black patients. This suggests continued systemic inequalities in stroke care settings.
A new study published in Ecology reveals traditional methods of tracking animal movement may be underestimating the actual distance travelled by whales, particularly for marine species.
The new book provides a comprehensive overview of engineered nanomaterials' interactions with biological systems, driving breakthroughs in biomedical applications and environmental sustainability. It explores critical applications in sustainable technologies, including bioremediation and heavy metal adsorption.
University Hospitals has received American Heart Association quality achievement awards for ensuring stroke patients receive best practices and life-saving care. The institution prioritizes early detection and treatment to improve survival, minimize disability, and accelerate recovery times.
A large meta-analysis of over 800,000 participants shows that high adherence to the Mediterranean Diet, Alternative Healthy Eating Index, and Dietary Approaches to Stop Hypertension reduces type 2 diabetes risk across diverse ethnic groups. These three diets have been recommended for general health and their potential benefits were fou...
Researchers map the path from liver fibrosis to cancer, revealing how scarred liver tissue becomes a breeding ground for tumor growth. Key findings include the role of hepatic stellate cells and dysregulated signaling pathways in remodeling the liver into a pro-tumor environment.
Researchers at WashU Medicine discovered that mast cells stand guard at tiny gates through which fluid waste leaves the brain, mounting a response when a pathogen is detected to close the gates and prevent invaders from entering. Enhanced mast cell activity before an infection reduced bacterial load.
A study merged rice growth models, genome-wide association studies, and machine learning to predict flowering time with high accuracy. The approach integrated climate indices and showed promise for precision agriculture and molecular breeding.
A new study uses GenAI models to extract pathological features for lung adenocarcinoma grading and prognosis, achieving striking accuracy and consistency. The research team discovered 11 key histological features and 4 clinical variables that provide a comprehensive risk assessment for patients.
Researchers found surprisingly high concentrations of small-diameter microplastics in air samples from their homes and cars, estimating adults inhale 68,000 particles per day. The study suggests health risks due to inhalation of lung-penetrating microplastics may be higher than previously thought.
Researchers at Max Planck Institute for Nuclear Physics have successfully detected antineutrinos from a nuclear reactor using the CONUS+ experiment. The detection uses Coherent Elastic Neutrino-Nucleus Scattering (CEvNS), allowing for improved sensitivity to new physics beyond the Standard Model.