A new study suggests that a low dose of ibuprofen can help alleviate chemo-brain symptoms in cancer patients, but exercise remains the most beneficial intervention. Researchers randomized 86 patients to receive either exercise plus ibuprofen or other treatments and found that exercise significantly improved cognitive function.
Researchers measured mitochondrial function using MRI in 11 cancer survivors, finding slower recovery time signals weaker function, but also a surprising correlation between worse mitochondrial recovery and lower fatigue. The study suggests that subjective experience of fatigue is multidimensional and not solely physical.
Researchers at Cornell University developed a soft robot gripper that can detect the ripeness of strawberries by touch, then gently twist them off their branch or vine. The technology has potential for more resilient and ecological food production.
A new study found that every type of epigenome protein produces a distinct pattern of gene expression, surpassing the on/off switch functionality. This discovery has significant implications for cellular engineering, enabling more dynamic control over cellular behavior and potential applications in biomanufacturing and bioproduction.
Researchers at University of Michigan created a stem cell model that produces a yolk-sac-like structure in a human embryo, mimicking early pregnancy loss. The model uses mechanical signals to guide development and does not require genetic manipulation.
Researchers show math underlying quantum gravity bears resemblance to quantum Hall effect, resolving cosmological constant problem. The Chern-Simons-Kodama state, a proposed ground state of quantum gravity, has a similar topology that keeps the cosmological constant's value stable.
A new study published in the Proceedings of the National Academy of Sciences found a link between elevated serotonin levels and tinnitus behavioral symptoms. The research suggests that clinicians should recognize and validate patient reports of medication-associated increases in tinnitus when prescribing antidepressants like SSRIs.
A new study found that pediatric patients with long-COVID experience a high symptom burden, including sleep disturbance, anxiety, depression, and fatigue. The study describes an interdisciplinary care approach that incorporates integrative medicine, nutrition, and lifestyle modifications to manage symptoms.
The Universitat Jaume I and AICE have established a joint GEA research laboratory to promote joint research and innovation in environmental engineering. The lab aims to foster knowledge transfer, train PhD graduates, and collaborate with companies in the region.
An international research team at the Mainz Microtron MAMI achieved the most precise measurement of hypertriton binding energy to date, revealing it is significantly more strongly bound than earlier experiments suggested. This breakthrough provides new insights into the interaction between hyperons and nucleons.
A global study has developed 15 internationally comparable indicators for climate communication and education, addressing the lack of reliable data on these essential actions. The indicators cover multiple dimensions of climate change mitigation and adaptation efforts.
Researchers from ICTER and the FDA Center for Devices and Radiological Health developed a new method to visualize the entire retina without refocusing. This breakthrough uses adaptive optics optical coherence tomography (AO-OCT) to generate three-dimensional retinal images with cellular resolution.
Researchers have developed a unified mathematical model explaining two types of 'breathing' solitons in ultrafast lasers, overcoming decades-old puzzle. The new framework accurately predicts complex behaviors and reveals underlying mechanisms.
Scientists discovered that deep-water coral ecosystems in the Galápagos region vanished for over 1,000 years due to prolonged La Niña-like conditions. The study found that these ecosystems may be more susceptible to climate change than previously thought, with significant implications for conservation efforts.
A study by the CNIO group has identified a genetic signature in precancerous breast lesions that can predict which ones will evolve into invasive tumours. This discovery could help avoid over-treatment of women diagnosed with ductal carcinoma in situ, a common precancerous lesion.
The discovery of seven millimeter-sized phosphatized fossils from the early Fortunian Kuanchuanpu Formation provides evidence of annelid body fossils from Cambrian Orsten-type fossil localities. The findings suggest that early annelids were polychaetes, supporting the hypothesis that polychaete morphologies were primitive among annelids.
Researchers developed a machine-learning model to predict protease behavior, enabling more precise and effective treatments. The ProSSpeC calculator suggests engineered synthetic proteases that outperform widely used enzymes.
Researchers found that connected natural habitats help maintain beneficial skin microbes that inhibit deadly fungal pathogens in tropical amphibians. Habitat fragmentation weakens these microbial defenses, leading to increased pathogen infection levels.
SourcePenn State·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateApr 20, 2026
Dr. Stuart Orkin has been awarded the Breakthrough Prize in Life Sciences for discovering genetic mechanisms underlying hemoglobin production and developing a therapy using CRISPR/Cas9 technology. The therapy, Casgevy, treats patients with sickle-cell anemia and beta-thalassemia, debilitating blood disorders affecting millions worldwide.
A new review highlights the role of intestinal stem cells (ISCs) and their supportive microenvironment in driving colorectal cancer initiation, therapy resistance, and relapse. Targeting the ISC–cancer stem cell ecosystem offers a promising strategy to develop next-generation precision care for patients.
SourceELSP·JournalAdvanced Cancer Research·TypeLiterature review·DateApr 20, 2026
A new study uses CRISPR technology to edit grapevine DNA, reducing vulnerability to downy mildew while improving water conservation. This breakthrough could lead to climate-resilient crops in Africa, addressing growing challenges in viticulture.
A new study reveals a significant link between obstructive sleep apnea and skeletal muscle quality, indicating an increased risk of muscle deterioration with aging. Researchers found that people with obstructive sleep apnea have lower skeletal muscle density and a higher skeletal muscle index than those without the condition.
The KIR-CAR T cell therapy has shown promising results in a Phase I clinical trial, demonstrating safety and increasing efficacy with higher doses. The treatment targets mesothelin, widely expressed on several solid tumor cancers, and limits side effects through its natural 'on-off' mechanism.
Researchers at TU Wien found that 2D materials are unsuitable for smaller electronic structures due to a tiny gap formed between the material and insulating layer. However, some materials can be combined with stronger bonds to eliminate this issue, potentially revolutionizing miniaturization steps.
Researchers tracked 30 patients with chronic blood cancers over time, finding that those whose disease remained stable had 'steady' blood cells without additional mutations. Conversely, those with progressing diseases developed changes in DNA years before symptoms worsened. This challenges current views on diagnosing patients without t...
The Helmholtz Association has launched a Water Safety and Security Campaign to protect human health and the environment. Two projects, URBAN-LE Solution Lab in Leipzig and SOLVE initiative in the Elbe River basin, focus on urban resilience and river ecosystem recovery through integrated approaches.
Researchers create molecular crystal with reversible color changes spanning from green to orange-red upon mechanical stress or pressure. The material exhibits adaptive intermolecular interactions and structural flexibility, enabling stimulus-responsive luminescence.
This review highlights the key findings of laser additive manufacturing of metallic lattice structures, including TPMS architectures, node reinforcement, and machine learning-driven optimization. The study demonstrates enhanced mechanical performance, energy absorption, and multifunctional capabilities such as thermal management and vi...
Compass combines Dimensions citation data and Altmetric attention metrics in a single platform, providing real-time publication intelligence. This solution addresses the fragmented data challenge faced by medical affairs teams, enabling them to make informed strategic decisions and communicate impact more effectively.
The report highlights rapid growth of solid-state implementation since SKKU's first successful realization in 2012, with China, US, and South Korea leading global research efforts. Sungkyunkwan University demonstrates world-class research competitiveness, ranking highly in key indicators.
A new AI framework combines digital pathology and structured clinical data to predict PIK3CA mutation status in breast cancer. The Multimodal PIK3CA Model outperformed single-modality models, achieving an AUC of 0.745, with strong performance across multiple clinical datasets.
Elif and Alp Tural teach interior designers to consider how spaces affect users every day, emphasizing trauma-informed design and visual accessibility. Their approach aims to create legible and comfortable environments that respond to users' needs.
Researchers discovered that HDAC7 plays a dual role in immune system development and cancer progression. Restoring HDAC7 in cancer cells can slow or stop tumor growth, offering new hope for diagnosis and treatment.
Researchers develop signal-processing method to suppress distortions, achieving 6mm spatial resolution in single-ended Brillouin sensing. This enables early detection of damage or abnormal conditions in aging infrastructure.
Researchers have identified a new geometric marker of the brain ventricles that can predict which patients with idiopathic normal pressure hydrocephalus (iNPH) will benefit from shunt surgery. The study found that a specific geometric feature, asphericity, is strongly associated with better surgical outcomes.
The Nordic Seas Overturning Circulation (NOC) has strengthened while the Atlantic Meridional Overturning Circulation (AMOC) has weakened due to global warming. Models project a slight increase in NOC's density-driven mechanism, which counterintuitively strengthens the northern branch despite AMOC weakening.
Dr. Eric Richards, a professor at BTI, has been awarded a 2026 Guggenheim Fellowship to investigate Daniel MacDougal's pioneering work on ovarial injection experiments in plant genetics. He aims to use archival research and modern DNA sequencing to determine if MacDougal's protocol actually created mutations.
Children who survive severe childhood malaria experience cognitive and academic impairment that persists into adolescence. The correlation highlights the urgent need for better prevention strategies and therapies to minimize lasting effects of the disease.
Astronauts experience difficulty transitioning between Earth and space due to brain predictions about gravity's pull. After prolonged periods in weightlessness, they overcompensate with their hand grip when returning to Earth, but gradually adjust over time.
Researchers at Hokkaido University developed a new method to measure small forces with high precision, discovering light can twist tiny objects sideways. This phenomenon depends on optical helicity, a subtle property of the light's electromagnetic field.
Researchers at NUS have developed a paired protein language model (PPLM) to predict protein interactions, improving accuracy by up to 17% over leading methods. The model has strong performance across multiple tasks and can capture biologically meaningful relationships between proteins.
Researchers review advanced AI algorithms and hardware acceleration techniques to predict material properties, optimize structures, and discover new materials. This review provides crucial guidance for accelerating data-driven materials research and fostering next-generation functional materials development.
Researchers at the University of Houston found that distraction disrupts memory consolidation primarily due to demands on central executive processing. To improve short-term memory, focus attention on a task for a few seconds before switching, and avoid multitasking.
Researchers at Saarland University have developed energy-efficient geometries for elastocaloric cooling elements using 3D printing. The technology uses shape-memory alloys to release heat when stretched and absorb it when released, promising a cleaner alternative to traditional cooling methods.
The American Geriatrics Society has honored 18 leaders in the field of geriatric medicine for their outstanding contributions to high-quality, person-centered care for older adults. These awards recognize individuals who have made significant impacts through education, research, and clinical practice.
Researchers at Ehime University discovered a π-stacked dimer of positively charged antiaromatic molecules stabilized upon stacking, contrary to their inherent instability. The findings suggest that intermolecular stacking can partially attenuate the intrinsic instability characteristic of antiaromatic molecules.
Professors José María Martín-Olalla and Jorge Mira Pérez refute the 2025 study linking Daylight Saving Time to negative health outcomes, citing a critical error in methodology. The original study's conclusions were based on an incorrect calculation of daily readjustments, which resulted in a zero annual cumulative total.
Scientists have demonstrated a reconfigurable photonic circuit implementing wide class of complex unitary transformations via optical manipulation at three layers only. The platform enables flexible access to many co-propagating structured modes, making it suitable for applications in communication, information processing, and simulation.
A new class of electrolytes has been developed that overcomes the bottleneck of water activity in traditional aqueous batteries. The electrolytes work with commonly used zinc salts and achieve exceptional electrochemical performance, including a wide stability window and ultra-long cycling life.
A retrospective study evaluates morphological irregularity parameters in Gamma Knife treatment planning for vestibular schwannoma patients. The analysis revealed strong correlations between these parameters and treatment plan outcomes, suggesting potential improvements in planning strategies.
Insilico's unified AI framework combines disease-specific predictive modeling with rigorous benchmarking to improve target identification accuracy and reliability. The validated system generates actionable intelligence, prioritizing targets with strong potential for successful development.
A new study removes bitter-tasting compounds from flaxseed oil, preserving its health-beneficial fatty acids and extending its shelf life. The approach uses bleaching earth to selectively reduce cyclolinopeptides, resulting in a flavor-stable oil that remains milder for longer.
The study found a concerning trend towards trial consolidation at top-performing sites in the US, with more limited access to clinical trials for lower-volume locations. This may be due to factors such as increased complexity of phase I trials and regulatory burdens.
A recent study identified distinct microbial signatures in the oral cavity and gut that serve as robust biomarkers for early gastric cancer detection. These microbial markers can be detected in saliva or stool samples using machine learning models, achieving an AUROC of 0.87 for saliva-based detection.
A new study reveals that strategically located poplar plantations can improve functional connectivity for forest birds in fragmented agricultural landscapes. The findings suggest that managed forests may contribute to both biomass supply and biodiversity conservation, particularly for species with moderate to high dispersal capacity.
A team of scientists has found that applying pressure to the heavy-fermion ferromagnet Ce5CoGe2 reveals superconductivity above a magnetic quantum critical point, defying typical expectations. The unusual phase diagram suggests that other ingredients beyond magnetic fluctuations may drive superconductivity in this material.
Researchers developed an AI model called Path-IO that uses machine learning to predict responses to immunotherapy for patients with metastatic non-small cell lung cancer. The model accurately stratified patients into high-risk and low-risk groups, with patients in the high-risk group having double the risk of death or disease progression.
Researchers have discovered two therapeutic vulnerabilities in LAR triple-negative breast cancer: ERBB2 mutations and senescence. Targeting these weaknesses with next-generation TKIs and immunotherapy could improve patient outcomes.
A digital single-session intervention (SSI) has been shown to meaningfully improve young people's sense of hope and control over their lives. The tool provides short, accessible and evidence-based psychological support and wellbeing activities, increasing feelings of hope and self-agency while reducing feelings of being out of control.
Researchers found that macrophages from CF patients display a pre-activated inflammatory state and exhibit exaggerated activation of NF-κB signaling. The extracellular matrix also acts as a persistent inflammatory stimulus, driving lung inflammation persistence despite CFTR function restoration.