A new study uses a human stem cell-derived model to identify potential therapies for inflammatory bowel disease (IBD), highlighting glycyrrhizin as a promising candidate. Glycyrrhizin significantly prevents intestinal cell death in both stem cell models and mice with IBD, reducing inflammation and cell death.
Researchers at Empa found that industrial chemicals, used in refrigerants and plastics, escape into the atmosphere at a rate of 3-4%, delaying ozone layer recovery by 7 years. These substances also emit significant greenhouse gases, posing a dual threat to the climate.
A team of researchers has identified a regulatory module centered on miR3699, MdMAN7, and eTM3699 that helps break down the cell wall of mature apple cells, promoting embryogenic cell formation and regeneration. Elevated MdMAN7 activity thins the cell wall, while miR3699 suppresses this process.
A new University of Kentucky Markey Cancer Center study identifies barriers to prescribing hormone therapy for cervical cancer patients who experience early menopause due to radiation treatment. Despite clinical guidelines supporting the use of hormonal therapy, research shows it remains underused. The study found that oncologists are ...
Researchers developed a powerful model to understand charge separation at the interface, influencing catalytic activity. The model provides insights into the formation of electric double layers and local electric potential variations.
A new single-chip camera captures ultraviolet, near-infrared and visible images using a compact design inspired by the multiwavelength vision capability of the mantis shrimp. The camera helps surgeons identify cancer-linked lymph nodes during surgery, making cancer treatment safer and less invasive.
Researchers have identified six key elements - meaning and purpose, life satisfaction, self-acceptance, strong relationships, autonomy, and happiness - as crucial for positive mental wellbeing. Experts say these factors can help policymakers better understand where to intervene in promoting mental health.
Researchers at City of Hope present findings on early-onset colorectal cancer, highlighting the role of gut microbiome differences and a new molecular pathway in immune resistance. The study uses AI tools to analyze complex relationships between data types, shedding light on potential strategies for earlier detection and treatment.
A new study has identified the WWOX protein as a molecular guardian that prevents common skin tumors from undergoing a dangerous metamorphosis and spreading to other parts of the body. The loss of this protein allows cancer cells to transform into more aggressive, invasive forms.
The newly discovered Bicharracosaurus dionidei is a 20-meter-long sauropod that shares characteristics of both Brachiosauridae and Diplodocids. Its fossil discovery in Patagonia provides valuable comparative material for understanding the evolutionary history of these animals in the Southern Hemisphere.
A recent study found that strengthening one's sense of belonging to natural environments has a protective effect against loneliness. The study investigated the impact of outdoor activities on loneliness and discovered that noticing details in nature, such as sounds and patterns, can be beneficial for mental well-being.
Research finds that the rounded shape of natural tips is due to random mechanical wear, not just evolutionary optimization. The experiment with pencils demonstrates how collisions can lead to a universal parabolic shape across different structures.
A new study from Florida Atlantic University challenges the narrative that rising temperatures will drive Americans away, finding that heat alone isn't driving large-scale out-migration. Instead, population shifts are shaped more by economic opportunity, housing affordability and local quality of life than climate conditions.
A specific protein, PKC-eta, has been identified as a central driver of aggressive breast cancer cell migration and metastasis. Reducing PKC-eta activity significantly slows tumor growth and reduces metastatic spread in laboratory and animal models.
A recent study published by the American Psychological Association found that people who rely heavily on AI programs for work tasks experience reduced confidence in their own independent reasoning. In contrast, those who actively challenge or modify AI suggestions report greater confidence and a stronger sense of authorship.
The 2026 cohort of Leon Levy Scholars in Neuroscience will pursue research projects addressing neurological disorders and developing new treatments. The program provides scientific and professional career development opportunities, including mentorship and networking.
A new remote psychological therapy program has been shown to improve symptoms and quality of life in young lupus patients. The six-session Treatment and Education Approach for Childhood-onset Lupus (TEACH) program incorporates cognitive behavioral therapy and mindfulness meditation to help kids manage depression, fatigue, and pain.
A new Washington State University study shows that recurring inflammation linked to endometriosis can sensitize the nervous system, driving lasting pain. This finding helps explain why pain persists even after lesions are removed.
A new coaching tool helps users identify biases in their prompts and generate more inclusive content. The study found that the intervention increased users' awareness of algorithmic bias and boosted confidence, but led to a less satisfactory user experience.
A recent study reveals that MLKL activation causes direct damage to mitochondria, impairing energy production and leading to functional decline in hematopoietic stem cells. In contrast, deletion or inhibition of MLKL significantly alleviates these defects, suggesting a post-transcriptional mechanism driving HSC aging.
A new study finds that warmer winters will lead to faster water transit times in the western United States, negatively impacting summer water levels and quality. The research focuses on the Naches River basin, where snowpack declines have already resulted in earlier spring discharges.
The device exhibits outstanding performance across a broad optical spectrum, with high responsivity and specific detectivity. Its polarization-sensitive detection capability enables the direct deciphering of light's polarization state without external filters.
A new study published in The Journal of Nutrition suggests that the widely cited 'adiposity rebound' may reflect lean muscle growth, not increased body fat. Waist-to-height ratio, a measure that better reflects body fat, continues to drop despite BMI increases after an initial decline.
Researchers at Chiba University have found that a balance between photocatalytic and photothermal processes is necessary for efficient CO2 conversion. The team achieved high rates of CO2-to-methane conversion by controlling temperature and light intensity, providing a pathway toward designing more efficient catalysts.
Research shows that nine weeks of Nordic hamstring exercise training increases eccentric knee flexor strength and allows participants to control the exercise through a greater range of motion. The study found that muscle fibers can stretch to longer lengths during exercise without overstretching, reducing injury risk.
Researchers found that Barrett's oesophagus is the starting point for all cases of oesophageal adenocarcinoma, even when telltale signs are no longer visible. The study suggests that detecting molecular markers such as TFF3 and REG4 could help identify individuals at risk of developing the disease.
Scientists calculate that high leakages of ozone-depleting substances from feedstocks could delay ozone recovery by about seven years. The Montreal Protocol made an exception for the use of these substances in producing other materials, but recent estimates suggest higher leakage rates than initially thought.
African elephants' genetic history shows they once moved across large distances, exchanging genes throughout the continent. However, current patchy habitats and human activities have led to genetic consequences of isolation, affecting conservation approaches.
A study analyzing Korean National Health and Nutrition Examination Survey data reveals higher awareness and treatment of major risk factors among Korean women with CVD, but lower control rates. Sex differences were observed in most management indicators, with men having more risk factors on average.
Researchers identify senescent macrophages as a driver of fatty liver disease, inflammation and aging. Clearing these cells reversed liver damage in mice on unhealthy diets.
Researchers at UCD have discovered a previously unknown courier system in cells that enables the transfer of coherent biological messages between cells. This breakthrough could lead to improved RNA-, gene- and protein-based therapies by ferrying functional biomolecules directly into previously inaccessible areas within cells.
The EU must reduce greenhouse gas emissions by 86% by 2040 to achieve 2050 climate neutrality through increased renewable energy and electrification. The study suggests a significant role for carbon capture and storage, with capacity needs rising by 26% annually from 2030 to 2040.
Scientists have confirmed the immense power of black hole jets, measuring over 10,000 times the energy released by the Sun. The research used a radio telescope array spanning the Earth to capture images of the 'dancing jets', revealing their movement pattern and speed, approximately half the speed of light.
Researchers at the John Innes Centre discovered a three-gene control hub that enables bacteria to share genes linked to antibiotic resistance. The study found that this mechanism is controlled by a bacterial immune system, which has been repurposed to release gene transfer agents.
A new laser method allows researchers to study radioactive elements like neptunium and fermium, which have rugby ball-shaped atomic nuclei. The technique provides crucial information about the size and shape of atomic nuclei, essential for understanding actinide properties.
A new tool identifies mangrove patches facing the greatest risk of degradation, allowing for proactive conservation. The Mangrove Threat Index provides a science-based way to identify areas where pressures are accumulating and where timely intervention can prevent long-term ecological and social costs.
Researchers discovered highly antibiotic-resistant bacteria in wildlife samples, including foxes and birds, indicating potential early warning system for AMR spread. The study highlights the need for environmental interventions to prevent resistance from reaching clinical settings.
Keratinocytes play a more active role in rabies infection than previously thought, supporting viral replication and transmitting the virus to neurons. This discovery provides new insights into the risk of infection from superficial scratches or minor bites.
Ricardo Baeza-Yates has made fundamental contributions to computer science through his pioneering work in algorithms and information retrieval. He has fostered a vibrant transnational research community across Latin America, inspiring young people with the South American Programming Contest.
The Journal of Management Analytics seeks high-quality research on the intersection of artificial intelligence and business disciplines, focusing on prescriptive intelligence to optimize organizational systems. The symposium will be held in June 2026 at ESCP Turin, Italy, with partial funding available for selected authors.
AEM expands its scope to cover the full breadth of modelling in agricultural and environmental sciences, introducing a structured range of article types for formal recognition. The journal applies FAIR principles to data, code, and models, requiring open access and reproducibility.
Researchers found that successive typhoons drive cumulative changes in chlorophyll a density, affecting ecosystem productivity. The study provides insights into forecasting variations in estuarine ecosystems during typhoon events.
Researchers discovered a new mechanism for deep earthquakes in the mantle transition zone, linked to the olivine-poirierite transition. The study found that a diffusionless phase transition of olivine to ringwoodite via poirierite releases high latent heat, weakening the fault gouge and inducing seismic activity.
A team from Dalian Institute of Chemical Physics proposed an atomic-to-macro multiscale electrode design to achieve high-efficiency and long-life hydrogen production. The design features abundant atomic heterointerfaces and tri-scale porosity, enhancing water electrolysis and improving mass transfer efficiency.
Researchers developed a novel hydrogel electrolyte that overcomes limitations of traditional hydrogels, enabling ultra-stretchability and anti-freezing capability. The material achieves high ionic conductivity and retains performance under severe deformation and extreme temperatures.
A team of researchers from Kyoto University has identified multiple types of stromal and secretory cells in the larynx, revealing new insights into vocal fold regeneration. The study's findings provide potential stem cells for treating vocal cord dysfunction and other voice disorders.
Researchers use global seismic networks and satellite observations to detect calving tidewater glaciers in Greenland. Large ice loss events are becoming more frequent, making it essential to understand their frequency, location, and factors leading to calving.
Researchers at USC, Caltech, and UC Irvine have developed a two-way brain interface that allows patients to control wearable robotic legs using their thoughts. The system accurately detected brain signals indicating the intent to walk about 92% of the time and restored walking sensations with about 93% accuracy in an early proof-of-con...
A new study suggests that a shallower Juan de Fuca slab beneath northern Oregon could increase estimated peak ground acceleration by 9-17% during Cascadia megathrust earthquakes. The research also identified a deep sedimentary basin beneath Tillamook, Oregon, which could amplify ground shaking and have been well-studied in other parts ...
Researchers tested swapping one meat-based lunch option for a vegetarian dish in six English worksite cafeterias, resulting in a 41% increase in choosing a veggie main. The intervention led to healthier and more sustainable meals with lower environmental impact.
Babies exclusively breastfed for at least three months have distinct epigenetic marks in their blood related to immunity and development. These findings come from the largest study on this topic, conducted across an international consortium.
A new Cochrane review of 17 clinical trials found that anti-amyloid Alzheimer's drugs have no significant impact on cognitive decline or dementia severity, but may increase the risk of brain swelling and bleeding. The evidence suggests that these drugs are unlikely to provide clear benefit to patients.
A new report estimates that sequencing DNA of all complex life in UK and Ireland could benefit the economy through improved crop resilience, medicine, and conservation. The Darwin Tree of Life Project has already saved research costs by providing over 2,500 reference genomes.
The FDA is reviewing a petition to revoke the approval of Roche's top-selling drug ocrelizumab for treating primary progressive multiple sclerosis in women due to concerns over its lack of effectiveness and potential increased risk of breast cancer. The investigation highlights internal FDA warnings about the drug's safety and effectiv...
New research suggests that relic black holes from before the big bang could help explain dark matter and several long-standing mysteries in cosmology. These primordial objects may have survived into the present day as 'cosmic fossils,' potentially influencing galaxy structure billions of years later.
Researchers at CU Boulder explore entangled particles for strong, adaptable materials. They found a 'two-legged' particle shape with optimal geometry delivers maximum entanglement, combining strength and toughness.
A new Simon Fraser University study suggests that freedom is a better gauge of happiness than positive feelings or pleasure. Autonomy, the feeling of being free to make choices, was found to be a stronger indicator of life satisfaction.
The underground laboratory in Nevada has extensive faulting, with signs of rock displacement and slickensides observed throughout the facility. The faults' age is unknown, and their potential impact on seismic safety designs is unclear.
A new study reveals that Waikiki is facing a fundamental shift in flood hazards as sea levels rise, transitioning from rainfall-driven floods to tidal process-dominated events. The team identified two key pathways, storm drain backflow and groundwater emergence, which will increase public exposure to sewage-contaminated waters.
A previously unknown floorplan has been discovered, pinpointing the exact location of Shakespeare's London property and revealing its layout and size. The finding challenges the long-held narrative that Shakespeare retired to Stratford after buying his Blackfriars house in 1613.