A team of NYU Abu Dhabi and University of Denver researchers have identified a promising small molecule, SK-129, that could slow or stop the progression of serious brain diseases such as Parkinson's disease. The molecule works by preventing the aggregation and spread of a neuronal protein, which damages brain cells over time.
Researchers found that a single general factor, called the 'Q-factor', captures how people rate their relationship across multiple facets. This means that many prominent self-report relationship measures may not be as empirically distinct as assumed.
A new soft sensing system allows humanoid robots to perceive complex finger posture in real time, enabling precise movement and dexterous manipulation. The system features an omnidirectional bending sensor that tracks pitch and yaw at the finger joints, providing stability and repeatability for demanding actions.
A compact chip holder with integrated electrodes enables temperature control, electric actuation, pressure handling, and optical readout for nanofluidic systems. The platform supports studies on molecular transport, catalytic reactions, and protein aggregation in confined environments.
Researchers developed a Rydberg dipolar atom chain approach for low-frequency vector electric-field sensing. The technique encodes field amplitude and direction into the many-body dynamical response, offering traceability, micrometer-scale spatial resolution, and vector sensitivity.
The NIH grant will support the creation of a comprehensive long-term dataset on Hispanic and Latino brain aging, examining the factors that matter most for healthy cognitive aging. The study aims to understand how Alzheimer's disease, vascular injury, and other brain changes develop over time in Latino adults.
A team of researchers has developed rechargeable batteries using biomass-based materials, including sunflower seed shells, as an alternative to lithium-ion batteries. The batteries achieved competitive results with low environmental impact and can store sufficient energy.
Research warns AI can compromise creativity, critical thinking with overly automated learning systems; 'learning vaults' suggested to safeguard adaptive knowledge. HR teams must ensure continued access to first-hand learning and human interaction.
The Deutsche Forschungsgemeinschaft will allocate funds for 14 new research units to drive cutting-edge scientific inquiry in Germany. These initiatives aim to boost collaboration and innovation across various disciplines.
The formation of freshwater lakes at the edge of Greenland's melting ice sheet is accelerating glacier flow, potentially increasing global sea-level rise. The lakes can destabilize glaciers, triggering movement and heightening ice loss.
The book chronicles two centuries of weather stories and observations, including Britain's longest continuous daily weather records. It highlights the diversity of British weather, from scorching summers to devastating floods, and shares insights into climate change.
A new study documents the rapid expansion of the Indo-Pacific crab Gonioinfradens giardi in the Ionian Sea, indicating a shift from sporadic occurrence to stable populations. The species' establishment raises concerns about its ecological role and interactions with native species.
Researchers discovered that DNA polymerases can generate highly sophisticated DNA sequences from scratch, with some exceeding 85,000 bases. By controlling the reaction conditions and temperature, scientists can steer the composition of the sequences produced.
The BBVA Foundation awards Carl Wunsch for his groundbreaking work revealing the ocean's central role in regulating Earth's climate. His innovative methods allow scientists to quantify ocean state under a changing climate, highlighting the need for a global ocean observing system.
A new AI chatbot helps patients access retinal detachment advice through personalized, real-time, clinically grounded conversations. The system outperformed leading large language models and includes accessibility features for people with low vision or limited English proficiency.
A genomic study found that cholera bacteria rapidly gain and lose defensive systems against a viral nemesis, ICP1, resulting in lower disease severity and reduced ability to spread globally. The study challenges the long-held belief that the Ganges Delta is the global source of cholera.
Researchers have confirmed that giant planets like Saturn operate under a unique magnetospheric regime, with a shifted cusp location due to its rapid rotation. This discovery alters models of magnetic reconnection and high-energy particle acceleration, revealing new insights into Saturn's auroral activity.
WorldFish Ventures aims to accelerate the scaling of aquatic food innovations through market-based approaches and strategic partnerships. The venture will focus on translating scientific breakthroughs into investable solutions that reach underserved markets more effectively and sustainably.
Researchers developed CausalBridgeQA, integrating causal inference into Multi-Hop Question Answering (MHQA) to address reasoning breakdowns and feature spurious correlations. The method significantly improves accuracy and robustness in complex questioning tasks.
Gravitational waves may have contributed to dark matter formation through stochastic gravitational waves during the early universe's formation. This new mechanism could lead to mass-free or nearly mass-free fermions that would acquire mass and form dark matter particles.
A University of Manchester Professor has been appointed as an Expert Reviewer for the NDA 2026 Review, led by Dr Tim Stone CBE. The review assesses the NDA's strategic planning, project delivery, and financial management to ensure value for money and highest safety standards.
Research at Tohoku University reveals that mushrooms adjust their communication levels in response to urine application, with increased flow when water is applied and decreased flow when urine is applied. The findings suggest that forest mushrooms can flexibly change their electrical information flow in response to various disturbances.
City St George's, University of London, is partnering with Paradigm Biopharmaceuticals to test a potential treatment for osteoarthritis. The partnership aims to investigate the mechanism of action of pentosan polysulfate sodium (iPPS) on bone marrow lesions, which are linked to pain in osteoarthritis.
The RFGDG framework uses a dynamic parameter aggregation strategy powered by Deep Reinforcement Learning to unify disparate feature representations and reduce redundancy across clients. This approach enhances global model accuracy and provides superior adaptability in multi-client environments.
Researchers at Aarhus University have developed an artificial virus-like DNA needle that can deliver molecules directly into cells. The technique uses DNA origami to assemble the needle and deliver its payload, potentially solving a major issue with many therapies being trapped inside cells.
Insilico Medicine will present four novel cancer inhibitors discovered via its Pharma.AI platform, targeting KRAS and Cbl-b pathways. ISM6166 and ISM3830 demonstrate robust anti-tumor activity against solid tumors with KRAS alterations and restored innate and adaptive immunity, respectively.
The research presents a comprehensive taxonomy of prompt engineering techniques, categorizing them by underlying principles and outlining a pipeline for designing effective prompts. This enables developers to optimize prompts for various applications, from creative content generation to high-stakes decision-making.
Researchers at KIT analyzed scientific papers using AI to identify emerging trends and relationships. The study suggests that large language models and machine learning can help reveal new avenues of research and opportunities for interdisciplinary cooperation.
A new UBC study found that global aquaculture production is increasingly relying on less beneficial species for food security, climate mitigation, and biodiversity. The industry's shift towards finfish has lower sustainability potential, while earlier systems like seaweed and shellfish had higher sustainability.
Researchers at Charité develop test to determine circadian rhythm using hair roots, revealing genetic and lifestyle factors influencing internal clock. The new method shows promise for tailoring therapies to individual rhythms, potentially improving treatment outcomes.
Researchers propose a novel approach to dataset acquisition in spatial data marketplaces, optimizing spatial coverage and connectivity under budget constraints. The proposed Budgeted Maximum Coverage with Connectivity Constraint (BMCC) algorithm achieves up to 68% larger spatial coverage with 89% speedups compared to existing methods.
Researchers propose adaptive protocol for GHZ states, combining short and long measurements to achieve high precision while maintaining dynamic range. This approach enables dual Heisenberg-limited scaling, surpassing older methods, and proves more resilient to noise and dephasing.
Research reveals a potential connection between gut microbiota and atopic diseases such as bronchial asthma and food allergies. Small intestinal bacterial overgrowth (SIBO) may contribute to the worsening of symptoms in these conditions. Further studies are needed to confirm this association.
Researchers challenge long-held assumptions about vegetation patterns in dryland ecosystems, finding that such patterns can actually indicate reduced ecosystem resilience. The new theoretical framework takes into account spatial constraints and environmental heterogeneities, revealing that ecosystem stability depends on specific enviro...
In this randomized clinical trial, mirtazapine effectively reduced methamphetamine use in adults with methamphetamine use disorder. The study's findings have important implications for the treatment of this condition, which currently lacks approved pharmacotherapies.
Scientists at the University of Manchester discovered a rare mathematical process underlying the formation of corrugations in soda cans. The sequence of buckles follows homoclinic snaking, a phenomenon where bumps or ripples appear one by one in a precise order.
A team of researchers discovered that inflammation in multiple sclerosis causes DNA damage to neurons essential for higher thinking and cognition. This finding provides a new direction for the field and highlights the importance of protecting grey matter neurons from damage.
Mohamed Abou-el-Enein, a USC physician-scientist, has received the Outstanding New Investigator Award and Best of Molecular Therapy Award from the American Society of Gene + Cell Therapy. His work focuses on translating scientific discoveries into clinical applications, with a particular emphasis on cell therapies.
A new study reveals that blocking the aryl hydrocarbon receptor (AHR) helps neurons regrow damaged axons and recover motor and sensory function. AHR acts as a key regulator that determines how neurons respond after injury, slowing down axon growth.
The review highlights LRRK2's diverse cellular functions and pathogenic mechanisms in various diseases, including Parkinson's disease and inflammatory disorders. Therapeutic strategies targeting LRRK2, such as kinase inhibitors and emerging approaches like PROTACs and gene therapy, show promise for correcting cellular imbalances and re...
A collaborative effort involving 865 researchers has published new empirical evidence on reproducibility, robustness, and replicability of social and behavioral sciences research. The SCORE program's outcomes will contribute to strengthening how research is interpreted and communicated.
Dr Amy Shirong Lu joins JMIR Serious Games as Editor-in-Chief with extensive research on digital health technologies and their impact on physical activity and cognitive health.
MDPI has opened its first US office in Philadelphia, serving as a central hub for scholarly engagement across the country. The new office will provide regional support to US scholars, manage scholar visits, and represent MDPI at conferences throughout the US.
A multi-site study found that AI scribes reduced electronic health record usage by 3% and clinical documentation time by 10%, with primary care physicians experiencing the greatest reductions. The technology also showed a slight increase in productivity, measured as 0.5 additional patient visits per week.
Current AI systems lack internal embodiment, a property that humans take for granted, which can lead to performance and behavior limitations. Researchers propose a dual-embodiment framework to guide future research in building safer and more aligned AI models.
Researchers at NIH have identified a novel opioid compound that shows potential as a therapy for both pain and opioid use disorder. The new drug, called DFNZ, has high pain-relieving effects without causing respiratory depression or addiction.
A 500-million-year-old fossil reveals the earliest known chelicerate with a claw, pushing back the evolutionary history of chelicerates by 20 million years. This discovery sheds light on the assembly of the chelicerate body plan and their early ecological context.
Between 2021 and 2024, government organizations accounted for around one-tenth of the estimated $336 million spent on advertising to news websites publishing health misinformation. Pharmaceutical companies also made notable contributions.
The adoption of AI-powered scribes was associated with modest decreases in total electronic health record time and documentation time. This is due to automation of routine tasks allowing clinicians more time for high-value patient care.
A new catalytic strategy using hydroxyl-induced cobalt oxide enables efficient conversion of syngas to light olefins through Fischer-Tropsch synthesis. The catalyst achieved high CO conversion and light olefin selectivity, with carbon utilization efficiency reaching up to 13%.
This study introduces a novel method that couples buoyancy-driven convection with localized acoustic microstreaming to enhance macroscopic mixing and microscopic mass transfer. The results show significant advantages in high-viscosity media, including increased effective coverage area and mean flow velocity amplitude.
A new UAV perching system utilizes a magnetic tensegrity-enabled robotic gripper with an adaptive energy barrier, enabling low-power and stable aerial operations. The system demonstrates rapid closure and high holding capability, with improved performance on rough surfaces.
The American Society of Hematology has published clinical practice guidelines for diagnosing and managing severe acquired aplastic anemia, a rare and life-threatening bone marrow failure disorder. The guidelines highlight the importance of shared decision-making between patients and providers, as well as the need for additional researc...
A new study found that popular vitamin B3 derivatives, commonly taken by cancer patients to manage chemotherapy side effects, can actually make cancer cells more resistant to treatment. This means that supplements like NMN, NR, and NAM may be undermining treatment in critical ways.
A recent FAU study found that individuals with prior criminal behavior, low self-control, and favorable attitudes toward deviance are more likely to access the dark web. The research highlights the importance of understanding who accesses this platform and why, particularly for those intending to engage in illicit activities.
A recent study reveals that Alaskan permafrost is thawing rapidly, leading to increased runoff, carbon releases, and altered coastal ecosystems. The research focused on a Wisconsin-sized area of Alaska's North Slope, simulating daily river flows and coastal exports over 44 years.
A review by an international team of researchers highlights that air monitoring is essential for global public health strategies, as airborne antibiotic resistance genes can spread silently between humans, animals, and the environment.
The NCCN 2026 Annual Conference emphasized the need for holistic care for adolescents and young adults with cancer, highlighting unique challenges and the importance of supportive services. The conference also addressed global cancer care realities and future strategies, emphasizing the need for collaboration and investment to address ...
A team of researchers found that Gli2 and Gli3 function synergistically to regulate tooth root morphogenesis. Their study revealed a critical interaction between HH signaling and TGF-β signaling, which is essential for normal root development.
A study published in BMC Public Health found an association between antibiotic use and maternal mental health during pregnancy. Researchers analyzed data from over 94,000 pregnant women and discovered a stepwise pattern of psychological distress linked to increasing antibiotic exposure. The findings suggest that avoiding unnecessary an...