A new metalens array architecture eliminates vergence-accommodation conflict and offers a wide field of view, achieving a 50° FOV 3D display. The system is highly scalable, with simulations indicating a 86° FOV limit.
Researchers found that smaller networks can be Pareto optimal, where no bank can be made better off without making another worse off. The study suggests that larger networks can lead to free-riding, reducing expected profits and market efficiency.
Researchers developed cellulose metafibers with a maximum tensile strength of 3.29 GPa and a toughness of 349.5 MJ m–3, comparable to top-tier synthetic fibers and natural spider silk. The biodegradable fibers were used in lawn and vegetation maintenance, showing wear resistance and environmental benefits.
A new evaluation framework helps bridge the lab-to-manufacturing gap for battery prelithiation technologies. The framework assesses eight prelithiation strategies across eight dimensions, enabling informed industrial technology selection.
DigBat brings together solid-state electrolyte data, simulations, machine learning, and AI to support battery materials research, providing a clearer view of the solid-state electrolyte landscape. Researchers can compare experimental and computational data, build machine-learning models, and gain insight from the data.
Researchers purified and characterized four ζ-carotene isomers, revealing UV-A shielding and antioxidant activities. The study suggests ζ-carotene's potential as a natural ingredient for skin health and photoprotection.
New research suggests that current conservation efforts are insufficient to halt the decline in common bird and butterfly species in Europe. The study projects a decline in species abundance across Europe up to 2050, with farmland birds and grassland butterflies facing strong pressures.
Researchers developed a covalently bridged interface engineering method to improve organic transistor stability, reducing leakage currents and increasing device performance. The design enables low-voltage operation and excellent charge-transport capability, making it suitable for flexible electronics applications.
FPR2 plays a pivotal role in maintaining intestinal homeostasis and promoting tissue regeneration through the PKC-ERK signaling axis. The study reveals that FPR2 activation regulates the proliferation and differentiation of intestinal stem cells and transit-amplifying cells, suggesting a potential therapeutic target for intestinal damage.
A study published in Life Metabolism reveals that high progesterone exposure during pregnancy can significantly improve menstrual cyclicity in PCOS patients and a PCOS-like mouse model. Postpartum, 60.60% of patients with irregular cycles showed improved menstrual regularity, with progesterone treatment normalizing estrous cyclicity an...
Researchers at Kumamoto University and collaborators developed a method to produce human trophoblast stem cells from late-gestation placentas, opening a new avenue for studying pregnancy complications. The resulting patient-derived models reproduce key features associated with preeclampsia, enabling the uncovering of molecular mechanis...
A new study found that fasting induces the accumulation of TCA cycle metabolites in brain lysosomes, which could support neuronal metabolic resilience. The researchers also propose three possible routes for the origin of these metabolites, including mitochondrial delivery and local interconversion supported by lysosome-associated signals.
A 10-year prospective cohort study in China found that ABC risk factors carry greater cardiovascular relevance in younger adults, while associations become less pronounced at older ages. Higher HbA1c, systolic blood pressure, and LDL-C levels were associated with increased cardiovascular risk, with varying degrees of strength across ag...
Researchers analyzed 42 pediatric ependymomas, identifying subtype-associated metabolic programs and linking them to clinical aggressiveness. The study found that the ST-YAP1 subtype had the most distinct metabolic profile, while the ST-RELA subtype was characterized by a lipid-utilizing metabolic program.
Exercise improves glucose tolerance and insulin sensitivity, restoring islet architecture and function in type 2 diabetes. The study reveals that exercise reduces inflammation and promotes a pro-inflammatory state in islet macrophages, which can compromise β-cell function.
A new PCSK9 vaccine candidate, PVC3, has been shown to induce sustained anti-PCSK9 antibodies and reduce hypercholesterolemia and atherosclerosis in mouse models. The vaccine also demonstrated a favorable preclinical safety profile, with no overt systemic toxicity or major histopathological abnormalities observed.
Endothelial CPT2 loss impairs fatty acid oxidation, promoting kidney fibrosis and renal injury. This impairment leads to reduced acetyl-CoA availability, activating an endothelial-to-mesenchymal transition (EndoMT)-like program.
Researchers identified a hierarchical nerve network in aortic perivascular adipose tissue, which is required for cold-induced blood pressure rise. Local ablation of sympathetic nerves in this tissue prevented cold-induced hypertension, underscoring its specificity.
Researchers found that ZRSR1 reduces hepatic lipogenesis and insulin resistance in mice, independently of minor intron splicing, by regulating the LXR-SREBP1c lipogenic pathway. This discovery broadens the known functions of minor-spliceosome proteins and reveals a new regulatory layer in fatty liver biology.
Researchers developed a unified scaling framework to separate quantum geometry contributions from disorder in nonlinear Hall data. The framework identified quantum-metric and Berry-curvature signals in existing second-order Hall data, allowing for clearer understanding of quantum-metric and Berry-curvature signals.
NTU Singapore's eVTOL aircraft successfully flew to heights above 90 meters and speeds of over 120 km/h, generating critical data on its performance. The aircraft demonstrated its ability to hover, fly using its fixed wings, and transition between modes, marking a milestone for Singapore's aerospace sector.
A prospective cohort study found that higher residential greenness was associated with lower type 2 diabetes risk in Chinese adults. Participants in the highest greenness tertile had a 51% lower risk of incident T2D compared to those in the lowest tertile, with the risk decreasing monotonically with increasing greenness.
Researchers found that magnetotactic bacteria AMB-1 extended lifespan by 43.39% and improved neurological function and intestinal integrity in aged worms. AMB-1 reduced iron accumulation and lipid peroxidation levels, suppressing ferroptosis and aging-related pathways.
Researchers have identified an enzyme from cow gut that can break down bacterial biofilm components, making them more vulnerable to antibiotics. The enzyme, CRhAB, was found to be effective against two notorious pathogen groups, including Acinetobacter baumannii, which poses a significant threat in healthcare settings.
Researchers propose a new AI framework, Generative Electrochemical Intelligence, to accelerate the discovery and development of electrochemical energy technologies. The framework combines generative AI with automated robotic experimentation to create a closed-loop system that can generate new ideas, test them, and learn from feedback.
Aqueous Zn-based flow batteries offer flexible design and low-cost zinc, but face issues with Zn deposition, crossover, and performance decay. Researchers call for integrated materials and reactor engineering to improve durability and energy density.
Researchers use µSR to investigate Li(Zn,Mn)As, revealing its ferromagnetic ordering and critical spin dynamics. The study provides a new understanding of the material's magnetic ground state and phase evolution.
The collaboration aims to advance molecular imaging research and develop new treatments for patients across the UK. Funded through charitable giving, the partnership brings together specialist radiopharmaceutical production and cutting-edge research, strengthening the UK's radiopharmaceutical research base.
Researchers from Zhejiang University developed a hybrid mode/wavelength division multiplexing transmitter chip using lithium niobate on insulator, achieving an aggregate capacity of 8.64 Tbps. The chip combines six modes and six wavelengths, enabling 36 independent channels with each supporting 240 Gbps transmission.
Researchers created a detailed map of B cell development and behavior in melanoma tumours, revealing new insights into immunotherapy response. The study identified an 'inflamed' B cell state that persists throughout disease progression and after treatment.
A new precision oncology paper critiques the methodology used in a 2025 study on mRNA vaccine residual DNA, arguing that it systematically underestimates DNA impurities. The analysis highlights key methodological flaws, including primer design, sample preparation, and analytical platform limitations.
Researchers developed an oral drug that can increase the ability of T cells to attack tumors, improving the efficacy of cancer immunotherapy. The gut-borne compound 3,4-dihydroxybenzoic acid trains T cells to become memory T cells, which drive anti-tumor immune responses.
The University of Texas at San Antonio School of Nursing has earned a second prestigious Center of Excellence designation in nursing education, recognizing its commitment to advancing innovative approaches to nursing education and student success. The school is one of only 19 nursing education programs nationwide to receive this design...
A new study by Michigan State University and Oklahoma State University found that bird nesting season in Minnesota prairies is declining, with 33 species showing a 22% drop in spotting likelihood over 16 years. The loss affects common birds, not just rare species, and is linked to climate change.
A new study links severe water scarcity in wheat-growing regions to global wheat prices, finding that 3°C of warming could triple average wheat prices. The study used climate observations, crop geography, and global commodity prices to explore this connection.
Hai Sun's $2.9 million NIH grant aims to improve pre-surgical mapping for epilepsy surgery by identifying critical brain nodes that trigger seizures. The goal is to make surgery safer and more effective for patients whose seizures cannot be controlled with medication.
A new study suggests that specific brain waves during sleep provide protection against the cognitive decline associated with elevated levels of the neurotransmitter orexin. Individuals with stronger sleep spindles and sleep oscillations during nonrapid eye movement (NREM) sleep had less cognitive decline over time.
Researchers have developed an mRNA immunotherapy that eliminates pancreatic tumors in mice, achieving complete tumor responses and long-term disease-free periods. The treatment uses a cocktail of immune cytokine and tumor-associated antigen mRNAs, showing promise as a potential transformative treatment for pancreatic cancer.
A study analyzed 1,694 articles and found an annual growth rate of 9.5% in research addressing climate change and animal production. The study also noted an increase in interdisciplinarity, methodological sophistication, and new agendas focused on sustainability, adaptation, resilience, and animal welfare.
A new study has discovered a molecular navigation system that precisely directs neutrophils to sites of infection, allowing them to fight off disease-causing microbes without damaging healthy tissue. This finding represents a promising therapeutic strategy for treating chronic inflammatory diseases.
Researchers create synthetic materials that selectively recognize and bind to biological substances, improving detection and removal of harmful pathogens. The materials combine recognition and absorption capabilities to enhance performance in complex fluids, supporting advances in water purification, disease monitoring, and food safety.
A new kinetic model couples lignin and hemicellulose dynamics to sharpen biorefinery predictions. The model uses controlled kinetics to release phenolic compounds and acetic acid gradually, turning lignin-derived inhibitors into measurable proxies for tracking bond cleavage.
Scientists at St. Jude Children's Research Hospital discovered removing Regnase-1 from engineered immune cells enhances CAR T-cell therapy's ability to control osteosarcoma growth and prevent metastasis. The modified cells also alter their tumor microenvironment, activating immune cells and reducing immunosuppressive signals.
AnalySwift, a Purdue University-affiliated company, has received a Phase II STTR award to develop a robotic welding technology that enables disassembly and reassembly of large truss structures in space. The technology will simulate advanced materials and structures needed for this activity, including the feasibility of repurposing full...
A study by Maximilian Krolo found that higher intelligence is associated with greater wine knowledge, even in the absence of external incentives. Professional experience strengthens the effect, while simply drinking wine alone is not enough to develop extensive knowledge.
The University of Illinois-led NSF HQAN has been renewed for a second phase with $37.5 million in funding to develop an industry-ready pathway for implementing modular principles in quantum computing. The center has made significant technical achievements and is building a quantum workforce through educational programs.
A new study found a 16.8-percent increase in HIV cases among Hispanic populations in antisanctuary counties compared to baseline counties. The researchers attributed this increase to the 2018 announcement of changes to the public charge rule, which penalized immigrants for using public benefit programs.
Researchers at Keck School of Medicine of USC will investigate PFAS as a risk factor for liver and endometrial cancers. The studies aim to understand the biological mechanisms linking PFAS exposure to cancer risk and identify ways to mitigate that risk.
The NRG-GU005 trial shows that SBRT improves bowel health related quality of life in localized intermediate risk prostate cancer patients, with no significant impact on urinary HRQOL. SBRT is also associated with lower incontinence related quality of life and improved maintenance of erectile dysfunction compared to hypofractionated IMRT.
A systematic review and meta-analysis published in Cardiology Discovery shows AI-guided spatiotemporal dispersion area ablation yields an 87% pooled 12-month freedom-from-atrial-fibrillation rate for patients living with persistent atrial fibrillation. The technique aims to standardize substrate identification while preserving patient-...
Researchers validated Japan's seismic design guidelines through full-scale shaking table tests, revealing hidden vulnerabilities in cable trays. A simple steel-wire reinforcement method significantly improves seismic performance in new and existing buildings, enhancing public safety and business continuity.
A study of 79,000 Chinese university students found that team ball sports showed the most favorable mental health outcomes, while individual aerobic activities were less beneficial. The study also found that exercise frequency and duration, such as 3-4 sessions per week and 90-120 minute sessions, were linked to improved mental health.
Researchers mapped a five-stage roadmap for magnetic soft robots to advance minimally invasive medicine, including untethered and tethered designs for various applications. The review highlights the importance of standardized testing, biocompatibility validation, and clinical validation to bring these promising robots from laboratory p...
A new study by La Trobe University found that families navigating family courts amid family violence face substantial costs, including legal services, healthcare, counseling, and security measures. The average expenditure per parent is over $41,000 a year, with mothers carrying the greatest security and healthcare costs.
Wearable sweat sensors provide continuous real-time monitoring in ICUs, offering insights into hydration and homeostasis through electrolyte and metabolite tracking. The technology has vast application prospects, including sepsis warnings, renal management, and precision glycemic control.
The University of Eastern Finland has contributed to the development of a new international measure for assessing productivity-adjusted life years, considering health-related functional capacity and productivity. The new study provides Finnish norm values for estimating life expectancy adjusted for these factors, enabling comparisons a...
Researchers at the University of Turku discovered a molecular mechanism that regulates the spread of aggressive colorectal cancer. The mechanism involves the secretion of mucus onto the surface of tumour spheres, which facilitates their migration and invasion of tissue.
Researchers at Bielefeld University have discovered that microcline's most common surface is sufficient for ice to form in an ordered manner, known as epitaxial growth. This finding provides a new perspective on the importance of uncommon ice faces for understanding ice nucleation.
A study found that Radix isatidis herbal residue supplementation improved growth, mucosal immunity, gut microbiota, and lipid metabolism in broilers. The residue also increased serum immunoglobulin A, lowered low-density lipoprotein cholesterol, and enhanced meat composition.
Researchers developed a novel adaptive model, BLAC-Q4DIM, to address ionospheric modeling errors. The model achieved dramatic improvements, reducing errors by 80-85% compared to standard GIMs and 58% compared to fixed-parameter Q4DIM, making it suitable for high-precision navigation and space weather monitoring.