Researchers at MIT have found that chromatin can exist in two different categories: constrained and free, which affects its interaction with genes and DNA regulatory sequences. This study provides insight into gene regulation and DNA repair processes.
A recent study found that older adults experiencing economic instability, poor housing, and fuel poverty are at a higher risk of physical and mental decline. The research, conducted over 14 years, suggests that living in precarious social circumstances can drive greater exposure to frailty in later life.
A study analyzing 100 million posts from underground cybercrime communities found that most cybercriminals lack the skills to use AI effectively, and its adoption has limited benefits for their work. However, AI coding assistants are mostly useful for already skilled actors, and poorly secured agentic AI systems pose a significant risk.
A pioneering study by the University of Eastern Finland confirms that total hip arthroplasty leads to better outcomes than conservative treatment for patients with moderate-to-severe hip osteoarthritis. The surgery significantly improved pain, functional capacity, and quality of life compared to conservative treatment alone.
A new paper outlines a practical framework for supporting residents' sexual health in long-term care, emphasizing autonomy, safety, and person-centered care. The framework establishes a Sexual Health Committee to develop policies and guide staff on sensitive aspects of care.
Researchers discover hydrogen radicals play central role in PFAS degradation under high-energy UV light, breaking down molecules into smaller, less persistent compounds. This breakthrough provides a clearer understanding of the underlying mechanism and challenges previous assumptions.
Researchers identified how Mycobacterium abscessus evades treatment and proposed a strategy to overcome resistance, offering a pathway towards more effective treatments. A combination therapy targeting both smooth and rough variants proved more effective than single-phage treatment.
A doctoral thesis reveals two drug molecules that can initiate the regrowth of a protective layer surrounding neurons, enhancing remyelination and accelerating brain tissue repair. The study also identifies scar tissue as a physical barrier to neural regeneration and demonstrates effective treatment with a second drug molecule.
When proteins become unbalanced, plant cells use a molecular recycling system to break down defective proteins. Central regulators NAC53 and NAC78 adjust this activity in response to stress, activating genes that strengthen protein breakdown while suppressing photosynthesis.
The International Osteoporosis Foundation is seeking an Editor-in-Chief for the European office of Osteoporosis International, a world-leading peer-reviewed journal focused on osteoporosis and metabolic bone diseases. The successful candidate will oversee content development, peer review, and strategic oversight of the journal.
Researchers at RMIT University have discovered that eucalyptus bark can be converted into a highly porous form of carbon that traps pollutants, providing a practical solution to clean polluted water and air. The findings highlight the potential of turning waste materials into useful environmental resources.
A new chemical pathway has been discovered that can convert amino acids into hydrogen cyanide without requiring methane. Manganese dioxide is the key mineral involved in this reaction, which occurs under a wide range of conditions resembling those of early Earth.
For the first time, researchers have identified the direction of neural signals in the brain using functional MRI. The study showed that feedforward and feedback nervous impulses each have unique signatures that can be detected with a new method called uFLARE.
A team of astronomers using a new method to find planets has detected 27 potential circumbinary planet candidates in double star systems. The findings, published in the Monthly Notices of the Royal Astronomical Society, broaden our understanding of planet formation and evolution in complex environments.
A team of researchers at Bielefeld University has developed a precise mathematical approach to plotting routes through space and time. The new method could help make space missions more efficient and also improve transportation systems on Earth.
Physicists at the University of Vienna have successfully extended the lifetime of magnons, tiny waves in magnetization, to a hundredfold, paving the way for mini quantum computers. The discovery reveals that materials science is key to further progress, rather than fundamental physics.
Unsecure firearm storage is common among older adults with subjective cognitive decline, despite clinical guidance recommending secure storage for those with cognitive symptoms. The study highlights the need for improved household practices and access to fire safety education.
A new Northwestern University study found that 60% of paternal deaths in Georgia between 2017 and 2022 were preventable, resulting from homicide, accidental injury, suicide, or overdose. The study also revealed that fatherhood appears to be protective for men, with lower death rates among those who are fathers.
A new study found that nonprofit hospitals spent at least $7.8 billion on management consulting services between 2010-2022, but saw no significant changes in finances, staffing, operations, or patient outcomes. The study suggests greater transparency and public accountability for how hospitals use tax-subsidized dollars.
A team of astronomers found a thin atmosphere around a small trans-Neptunian object (TNO), which is not expected to retain atmospheres due to its cold temperature and weak surface gravity. The atmosphere is thought to be less than 1000 years old, suggesting recent formation or replenishment.
This article provides an overview of anxiety disorders, including their symptoms, diagnosis, and treatment options. The study found that anxiety disorders can be effectively managed with a combination of therapy and medication.
A research team at Hiroshima University has discovered the key gene GEMMIFER responsible for initiating asexual reproduction in the model plant Marchantia polymorpha. The gene is essential for gemma development, acting as a master switch to start cloning in this plant species.
A new physics-based simulation framework predicts the likelihood of failure for different transmission tower designs across entire networks with 96% accuracy. The model accounts for various factors, including wind speed and direction, and rainfall intensity, to help power companies identify vulnerable towers and reduce power outage risks.
The American Medical Association (AMA) has developed guidelines for treating anxiety disorders in adults in primary care settings. Behavioral therapy, including cognitive-behavioral therapy (CBT), and medication, such as selective serotonin reuptake inhibitors (SSRIs), are recommended treatments.
Scientists have discovered a previously undescribed nematode species, Caenorhabditis apta, which forms 'towers' that can attach to fruit flies and other insects. The study found that two sap-feeding beetles are likely the primary vectors of this new species, highlighting the importance of understanding how nematodes spread in the wild.
Hospital-based shootings in the US have increased over 25 years, with large hospitals and urban areas being high-risk settings. The study emphasizes the need for hospital-specific prevention strategies, including weapons screening technology, to address rising firearm violence.
Recent shifts in federal policy and funding have impacted hundreds of clinical trials designed to study disease burdens in underrepresented populations. The report highlights a systemic crisis in medical research, citing a disruption at scale that has affected over 74,000 participants across 383 trials.
Astronomers using the James Webb Space Telescope discovered a galaxy that is not rotating, contradicting current theories about galaxy formation. The team believes this galaxy may have been formed after a single collision between two galaxies, making it a rare and unexpected finding.
Researchers found that providing food baskets to households affected by TB can prevent 10,470 years of poor health or early death for every 10,000 patients. The intervention is estimated to be cost-effective, costing $141 per health gain, and could avert approximately 120,000 TB deaths per year nationwide.
Nir Barzilai, MD, and Richard J. Hodes, MD, will receive the George M. Martin Lifetime Achievement in Mentoring Award and Irving S. Wright Award of Distinction, respectively, for their contributions to aging research. Marianna Sadagurski, PhD, is the recipient of the Vincent Cristofalo Rising Star Award in Aging Research.
Researchers at Cal Poly have discovered a way to create exotic quantum matter by controlling the timing of magnetic fields. This breakthrough could lead to more stable and error-free quantum technologies, including quantum computing and simulation.
Researchers at the University of Colorado Boulder have discovered that experienced ballroom dancers' brains synchronize when they move together. The study used EEG caps and movement sensors to track brain activity and found that neural synchronization increased as dancers moved in sync, revealing a phenomenon called interbrain coupling.
Researchers at Princeton University developed a system to mimic natural structures' microstructural patterns and mechanical properties. By combining origami and tensegrity, they found that the same equation describes both engineering structures, enabling designers to create irregular shapes with less computational complexity.
A recent study found that cranberry juice enhanced the antibiotic activity of fosfomycin against 72% of uropathogenic E. coli strains, while suppressing resistance-related mutations. The findings suggest that natural compounds in cranberry juice may be a useful frontier in fighting antibiotic resistance.
Researchers have identified a signaling pathway that prompts plant cells to form walls, revealing the process of how cell walls create plants' shapes and structure. This discovery sheds light on how plant life evolved and sustained human civilization.
The International Progressive MS Alliance has launched the MS Clinical and Imaging Data Resource (MS CIDR) to accelerate understanding of MS progression. The resource contains anonymized data from 14 pharmaceutical industry clinical trials, including MRI scans and clinical visits data from over 13,000 people with progressive MS.
Researchers discover that using filters with larger pore sizes significantly improves the recovery of eukaryotic DNA in seawater samples, allowing for more accurate detection of marine life. This breakthrough could enhance the application of environmental DNA analysis in biomonitoring and conservation efforts.
A coordinated 10-year plan to improve long-term wellbeing and reverse child obesity trends is underway. The GenHEART program, spearheaded by Murdoch Childrens Research Institute, targets heart health, diet, exercise, sleep, and more.
Researchers fine-tune a new type of glass made from metal-organic frameworks (MOFs) that efficiently trap gases like CO2 and hydrogen. The discovery provides a new design framework for making customized MOF glasses with tailored properties, enabling applications in gas separation, chemical storage, and advanced coatings.
A new study published in Communications Sustainability reveals that investing in renewable energy yields more combined climate and public health benefits than direct air capture. The analysis models the health and climate benefit of cost-equivalent deployments of DAC, solar, and onshore wind across US grid regions from 2020 to 2050.
Researchers argue that Louisiana's climate-driven land loss and population shifts could position the state as a global leader in planning for climate adaptation. The study combines coastal geology with archaeology, demography, and public policy to outline a long-term vision for the region.
The team analyzed LHS 3844 b's infrared radiation, finding it doesn't match Earth-like silicate-rich minerals. Instead, the spectrum suggests a dark, rocky surface composed of basaltic or magmatic minerals, possibly with a recently active geological history.
Researchers have identified a novel genetic locus in the common agricultural weed Elymus repens that provides significant resistance to Fusarium Head Blight, a destructive fungal disease threatening global food security. The novel Fhb.Er-1StL locus has been successfully transferred into wheat, reducing diseased plant spikelets by up to...
High-intensity interval training shows strongest vascular benefits in cardiovascular patients. HIIE consistently improves flow-mediated dilation and vasodilation, with combined high-intensity programs showing the largest estimated effects on endothelial function.
Research finds that warmer autumns delay lake freezing, leading to colder winter under-ice temperatures. Autumn surface waters have also warmed by an average of 1.85 °C, while large lake size and strong winds influence under-ice bottom water temperatures.
Researchers at ETH Zurich created a machine-learning-based map showing Europe's most beautiful and scenic regions. The study found that excluding these areas would reduce wind energy potential but increase costs per unit of electricity generated.
Researchers found that accelerated biological aging of a type of white blood cell called monocytes is linked to cognitive and mood-related symptoms of depression. This discovery could lead to earlier diagnosis and personalized treatment for depression, particularly in high-risk populations such as women with HIV.
The new recommendations provide a practical approach for clinicians to initiate conversations about alcohol use and identify potential problems earlier. The guidelines update offer easy-to-use tables with tips on reducing alcohol use, helping clinicians focus on patients' unique needs while saving time when circumstances allow.
A new study suggests that fitspiration content on social media can lead to negative self-esteem, unhealthy dieting, and exercise habits among young adults. Researchers analyzed 26 studies involving 6,111 individuals across seven countries, finding that even brief exposure to idealized images can trigger harmful comparisons.
More than 50% of people with diabetes develop diabetic peripheral neuropathy, which causes painful sensations like burning, tingling, or shooting pains. The brain and spinal cord can also contribute to pain, as their pain-blocking systems are less effective in people with diabetes.
Researchers at NUS create Lytic Selection and Evolution (LySE) platform, harnessing modified bacteriophage to rapidly create and test genetic changes. After five cycles, plastic degradation improved by over 50%, demonstrating a faster and more controllable method for training bacteria to consume plastics.
A new study highlights the importance of involving older people in technology design to ensure devices are useful, respectful, and culturally appropriate. Co-design helps build trust and ensures technologies support older people's autonomy and dignity.
A new approach has been proposed to address the problem of overconfidence in AI, enabling it to recognize situations involving unfamiliar or unseen knowledge. By incorporating key principles of brain development, AI can develop the ability to distinguish 'what it knows' from 'what it does not know', a crucial step towards meta-cognition.
Researchers at Michigan State University have developed a digital twin tool that uses AI and laser mapping to test different management strategies in simulated pine forests. The tool predicts trunk diameter and volume with high accuracy, enabling targeted treatments to minimize waste and bolster financial returns.
A long-term MRI study finds that lower accumulation of visceral fat is associated with preservation of key brain structures, better cognitive performance, and slower brain atrophy. The study suggests that glucose control and insulin sensitivity mediate the relationship between abdominal fat and brain aging.
A new method for measuring homogeneity in transparent cylindrical materials has been developed, allowing for non-destructive inspection without slicing. This approach significantly reduces costs and improves quality control, making it suitable for industries such as semiconductor manufacturing and medical imaging.
A team of scientists developed a wafer-level-manufactured meta-aspheric lens that achieves simultaneous wide field-of-view, ultrathin form factor, and high imaging quality. The design enables compact near-infrared imaging systems with robust performance in eye tracking, blood vessel imaging, and computational pixel super-resolution tasks.
A new study from Karolinska Institutet shows that low doses of endoxifen reduce breast density to the same extent as tamoxifen without causing severe side effects. The results suggest a lower dose may be sufficient for therapeutic effect while being better tolerated.
Creatine supplementation has been shown to increase muscle energy and improve cognitive function, particularly in populations with lower baseline creatine levels. Emerging evidence also explores its potential therapeutic applications for conditions like Parkinson's disease and menopause-related muscle loss.
The Arctic winter sea-ice extent reached a new record low in 2026, following the previous record low in March 2025. Temperatures in the Sea of Okhotsk and Baffin Bay-Labrador Sea region remained higher than average, limiting the southward expansion of sea ice.