The EVEREST project, funded by the EU, aims to standardize methods for isolating and characterizing extracellular vesicles. This could lead to non-invasive diagnostics and personalized therapies for complex diseases like cancer and cardiovascular conditions.
A large-scale survey of over 1600 biomedical researchers identified common causes of research irreproducibility, including inadequate experimental design and lack of standardization. The study provides insights into the challenges faced by researchers in reproducing their results.
Researchers developed a new AI model, BiomedGPT, to support various biomedical tasks. The model achieved 16 state-of-the-art results in 9 biomedical tasks and demonstrated robust predictive abilities.
The University of Central Florida has established a new research lab to advance light-based technologies for disease prevention, detection, and treatment. The interdisciplinary lab will facilitate collaborations between physicians, scientists, and researchers from various fields, including biophotonics and biomedical sciences.
Pennington Biomedical researchers will lead courses, presentations, and speaker panels at ObesityWeek 2024, showcasing exceptional obesity research. The center's faculty, postdoctoral fellows, and staff will engage with global potential collaborators and demonstrate progress in metabolic health.
Researchers developed a screening technique to filter out low-quality data in wearable sensors, improving the performance of smartwatches for noninvasive blood glucose estimation. The approach enhances accuracy by discarding data with high phase errors and approximating missing values.
The EAT2 study, led by Dr. Ursula White, investigates the lasting health effects of short-term weight gain and loss on fat tissue and overall health. Participants will undergo a dietary intervention program followed by an eight-week weight loss treatment.
Researchers at Texas Biomedical Research Institute developed a human cell culture model of alveolar macrophages, which helped make a key finding about the role of tumor necrosis factor (TNF) in tuberculosis (TB). The study found that TNF is critical to protect against TB but not other infectious diseases.
A new study proposes a theoretically new mechanism to modulate spinal reflexes at the same spinal cord level as stretch reflexes during voluntary movements. The research, led by Biomedical engineering doctoral student Grace Niyo, suggests that a simple spinal circuit can correct self-perturbations from stretch reflexes to produce smoot...
Researchers are conducting a comprehensive health and nutrition examination study to assess the status of active-duty service members. The study will gather data on dietary intake, nutritional status, cardiovascular health, and other measures to guide evidence-based screening and intervention strategies for improving health in the mili...
Biomedical engineers at the University of Rochester have developed a novel technique using ultrasound waves to organize endothelial cells into patterns that promote the growth of new vessel networks. The team aims to treat ischemic injuries caused by damaged tissue in reconstructive and plastic surgeries.
The gift will support the expansion of the Vagelos-funded institute, construction of a new biomedical research building, and innovative collaborations in cell engineering and gene therapy. This investment aims to revolutionize treatment for various diseases, representing a new paradigm in medicine.
Researchers at Pennington Biomedical are conducting a 12-week study to examine the impact of soy on blood sugar, mood, and energy levels. Participants will receive meals with or without activated soy flour and undergo various tests, including insulin sensitivity and bone density assessments.
ProDOL, a novel microscopy technique, enables precise quantification of labelled proteins in living cells, overcoming existing limitations. The method's accuracy and versatility make it a valuable tool for biomedical research, particularly in understanding cellular signalling processes.
Dr. Elks' research focuses on the communication loop between fat cells and immune cells, which promotes inflammation and insulin resistance when disrupted. The grant aims to uncover patterns in cell communication that can be used to treat obesity and other metabolic diseases.
The paper explores evolving landscape of genetics research into obesity, emphasizing both new discoveries and challenges. Researchers highlight complexity of body weight regulation and advocate for precise phenotyping methods targeting relevant and refined phenotypes related to adiposity.
ChatGPT has shown impressive capabilities in tasks related to knowledge-mining and text-generation, but exhibited limitations in quantitative analysis and reasoning. The researchers emphasize the importance of human expert augmentation and efficient prompt engineering to minimize hallucination and improve response accuracy.
The grant will be used to investigate the genetic mechanisms underlying fentanyl addiction, with a focus on identifying genes and brain mechanisms that contribute to vulnerability and resistance to addiction. The research aims to pave the way for the development of novel, more effective treatments for fentanyl addiction.
African American woman breast cancer survivor talking about her experience with breast cancer and the impact of breast cancer on women's lives. The American Cancer Society is a leading organization in cancer research, patient services, and advocacy.
Researchers are exploring inflammation caused by COVID-19 as a trigger for Long Covid, a condition characterized by persistent symptoms like fatigue, brain fog, and shortness of breath. The study aims to identify potential causes and treatments for Long Covid, with findings that could lead to enhanced immune function in patients.
Chi-Min Ho, assistant professor at Columbia University Irving Medical Center, has been awarded the Pew Biomedical Scholars Program for her innovative work on malaria parasite biology. Her team plans to use integrated structural biology approaches to deepen our understanding of malaria parasite biology.
The Pennington Biomedical Research Center is conducting a clinical trial to better understand lipedema. Participants will undergo comprehensive assessments and imaging techniques to help advance medical knowledge related to chronic disease. Compensation of up to $475 is offered for participation in the three-month study.
The ACCELERATE program aims to enhance educational experiences of HCC students, providing access to resources and opportunities for biomedical research training. Students will participate in extracurricular laboratory modules, immersive research training, and mentorship programs.
Dr. George Bray's paper tracks the development of obesity research over 100 years, from early explorations to modern medication interventions. The study highlights the chronic and relapsing nature of obesity as a disease process.
A study of young people in contact with mental health services found that half met criteria for problematic smartphone use. The study also revealed high levels of sleep disturbance and self-harm among the participants.
Nach0 was trained on diverse tasks, including natural language understanding, synthetic route prediction, and molecular generation. The model performed well on molecular tasks using molecular data and outperformed ChatGPT, making it a significant step toward unlocking the full potential of LLMs for drug discovery.
F. William Studier, a senior biophysicist at Brookhaven National Laboratory, has won the 2024 Merkin Prize in Biomedical Technology for his T7 expression technology, enabling large-scale production of RNA and proteins for biomedical research and pharmaceuticals. His work has saved millions of lives with COVID-19 mRNA vaccines.
Researchers at George Mason University's Biomedical Research Laboratory are conducting Plaque Reduction Neutralization Tests (PRNTs) on patient serum samples from Athari BioSciences. The study aims to analyze the neutralizing ability of antibodies against SARS-CoV-2.
Researchers from Technion Faculty of Biomedical Engineering developed a breakthrough method for bio-printing live cells and tissues using external sound wave irradiation. The innovation enables precise localized delivery of biocompatible materials for various biomedical applications, reducing invasive surgeries and associated risks.
A study published in the New England Journal of Medicine provides recommendations for protein, carbohydrates, fat, fiber, and water intake at various stages of life to support overall health. The guidance, developed by Dr. Steven Heymsfield and Dr. Sue Shapses, aims to promote personalized diets with key macronutrients.
Researchers are developing a living knee replacement made from biomaterials and human stem cells, including patient's own cells. The goal is to create a permanent solution for patients with advanced OA where conventional knee replacements fail.
The Vilcek Foundation will award three prizes of $50,000 each to young immigrant scientists in the US whose early career work has a significant impact on their field. Applications close June 10, 2024, and prizewinners will be selected by a jury of biomedical science experts.
A minimal metadata set (MNMS) is established to enable in vivo data reuse and improve the sharing and reproducibility of research data. The MNMS is designed to contribute to making data from living animals compliant with the FAIR data concept, which emphasizes Easy-to-Find, Accessible, Interoperable, and Reusable data.
Researchers at UNSW Sydney have developed a new technology offering test strips for rapid, on-the-spot disease detection. The test strips are accurate and cost-effective, making them suitable for various applications including public health, environmental diagnostics, and cancer cell detection.
A new study highlights the contributions of 50 top scientists from elite universities to transforming medicine through cutting-edge biomedical engineering advances. Five primary medical challenges are identified, including precision engineering for personalized care and tissue engineering for human health.
Researchers at Pennington Biomedical confirmed the accuracy of remotely gathered physical measurements for children in a weight management study. The findings support the value of remote height and weight measurements for both research and clinical purposes.
A consortium of 50 renowned researchers from 34 prestigious universities identifies five primary medical challenges that can be addressed with advanced biomedical engineering approaches, aiming to improve human health. The paper outlines a roadmap for groundbreaking research and funding to achieve technological and medical breakthroughs.
A 12-year study published in JAMA found that bariatric surgery significantly improved blood glucose control and type 2 diabetes remission compared to medical management alone. Participants who underwent bariatric surgery experienced greater weight loss, reduced medication use, and higher rates of diabetes remission.
A study by 50 experts reveals five cutting-edge biomedical engineering advances with significant applications in medicine, including precision engineering, on-demand tissue engineering, and advanced brain interface systems. These advances aim to transform the practice of medicine, impacting various conditions and diseases.
A new roadmap has been published by IEEE EMBS, outlining five primary medical challenges that need to be addressed through advanced biomedical engineering approaches. The paper, written by 50 renowned researchers from 34 prestigious universities, aims to guide future research and funding for groundbreaking innovations.
Researchers found that a compound called BAM15 makes mitochondria less efficient at producing energy, extending life span and improving body composition in fruit flies. The study also showed reduced age-related decline in motor activity. Further studies are needed to confirm these findings in humans.
A new screening tool has been developed to catch endometrial cancer cases earlier, saving lives. The partnership between Pennington Biomedical's Metamor Institute and the LSU School of Medicine has already screened over 2,000 women and found abnormal bleeding in many cases.
Researchers have confirmed a new method for precise body composition analysis using 3D surface scans and dual-energy X-ray absorptiometry. This approach yields accurate measurements of fat, lean muscle, and bone, surpassing commercial software in clinical settings.
Researchers at Virginia Tech's Fralin Biomedical Research Institute found applying low-intensity focused ultrasound to the brain can reduce pain perception, brain activity, and cardiac responses. The non-invasive technique may provide a new therapeutic option for chronic pain treatment.
Researchers developed a compact, cost-effective PA sensing instrument for biomedical tissue diagnosis, showcasing its potential to streamline sampling processes and improve diagnostic accuracy for breast disease. The instrument successfully differentiated various tissue types based on quantitative spectral parameters.
A team of researchers has developed a novel mixing device that produces nanomedicines directly at the point of care, enabling rapid and cost-effective synthesis of personalized vaccines. The technology has potential implications for cancer therapies and infectious diseases.
The Vilcek Foundation has awarded $250,000 to four immigrant scientists for their pioneering work in biomedical science. Luciano Marraffini, Gerta Hoxhaj, Tomasz Nowakowski, and Takanori Takebe are recognized for their contributions to cancer research, pluripotent stem cells, and CRISPR-Cas systems.
Researchers at Pennington Biomedical aim to investigate the effects of intermittent fasting and calorie counting on healthspan. Participants in the DiAL-Health study will be compensated up to $2,500 for their involvement.
Researchers at Fralin Biomedical Research Institute and Carilion Clinic found that preserving leg vein grafts in heparinized arterial blood, rather than saline, improves their health and viability. This discovery could lead to better outcomes for patients undergoing coronary artery bypass graft procedures.
Flori Corpodean, a postdoctoral researcher at Pennington Biomedical, has been selected as the sole recipient of the 2024 Resident Research Award. She is exploring how the brain and intestinal tract communicate through her research on altered nutrient delivery.
A team of engineers has developed a novel printing method called deep-penetrating acoustic volumetric printing (DVAP) that uses soundwaves to solidify biologically compatible structures in deep tissues. The technique involves a specialized ink that reacts to ultrasound waves, enabling the creation of intricate structures for biomedical...
Researchers aim to determine optimal duration and intensity of behavioral interventions for childhood obesity among rural and minority children. The five-year study, funded by the Patient-Centered Outcomes Research Institute, will enroll 900 parent-child pairs and compare different 'dosing' combinations of face-to-face intervention time.
Scientists from SLAC National Accelerator Laboratory have gained valuable insights into producing nitroxide, a molecule with potential applications in the biomedical field. The team employed advanced X-ray spectroscopic techniques to understand the intricacies of the nitroxide production process and its bond-breaking mechanism.
Alem & Narayanan receive $2,495,244 from the National Institutes of Health to enhance safety and quality of BSL-3 laboratory practices and create two new research cores in high containment. The grant will accelerate vaccine and therapeutic drug discovery and improve understanding of infectious disease transmission and pathogenesis.
Researchers from Icahn School of Medicine at Mount Sinai and the University of California San Diego will lead a new data integration hub aiming to accelerate novel therapeutics and cures for diseases. The grant, worth $8.5 million, is part of the NIH Common Fund's efforts to enhance data findability, accessibility, interoperability, an...
An international team of scientists recommends a global shift in food choices due to the potential for addiction. They suggest that certain ultra-processed foods have characteristics similar to addictive substances, which may improve global health.
Insilico Medicine has identified 9 potential dual-purpose targets against aging and 14 major age-related diseases using Microsoft BioGPT. The proposed genes include CCR5 and PTH, which have not been previously correlated to the aging process.
A team of researchers identified a protein called RAC2 that appears to drive the foreign body response, which causes the body to reject biomedical implants. Suppressing production of this protein could reduce the risk of implant rejection and improve the design and safety of implants.
Two renowned biomedical researchers, Professor Emile R. Chimusa and Professor Simon Johnson, have been awarded £1 million to conduct world-leading research into prostate cancer and mitochondrial disease. The grant will support the establishment of new interdisciplinary research teams and advance medical science.
The new facility will enhance the lab's capabilities to study the impact of chemicals and nanomaterials on human health, with applications in areas like toxicology and disease prevention.