Researchers found that individuals with autism have lower levels of GABA, a key inhibitory neurotransmitter, which suggests a breakdown in the signaling pathway. This breakthrough could lead to early intervention efforts through visual screening tests for younger children.
Researchers have discovered a direct link between autism symptoms and reduced action of the inhibitory neurotransmitter GABA. The study suggests that increasing brain concentrations of GABA may have potential as an autism treatment.
Researchers have discovered that autism-relevant biomarkers can be measured in adult saliva, providing a promising avenue for non-invasive diagnosis and treatment. The study, which analyzed levels of 10 biomarkers in saliva from neurotypical adults, brings us closer to effectively diagnosing and treating autism.
Researchers have uncovered a significant relationship between a chemical transmitting brain signals and genetic mutations in individuals with autism spectrum disorder. Targeting a specific serotonin receptor, 5-HT2cR, can reverse social deficits in mouse models of the autism risk gene Pten.
Researchers at UCI have found a biomarker for diagnosing certain forms of autism, which involves a cellular calcium signaling process. The study also points to potential new drug discovery advances by targeting the inositol trisphosphate receptor, a key player in this process.
A large study of individuals with autism found that both men and women with the condition performed similarly to typical males on an empathy test. This result supports the 'extreme male brain' theory, which predicts lower empathy scores in individuals with autism compared to females.
A University of Miami research team proposes a four-component model of cognitive flexibility, which helps understand autism spectrum disorder and other behavioral/neurological disorders. The study may inform the development of new interventions to improve cognitive flexibility skills in individuals with autism.
Researchers found significant gender differences in the severity of repetitive and restricted behaviors in girls with autism compared to boys. The study also identified distinct brain structure differences between boys and girls with autism, particularly in motor regions.
Dr. Kristin Sohl is expanding the ECHO Autism program to an additional 10 sites, aiming to improve healthcare for children with autism in underserved communities. The $15 million grant will enhance early identification of autism and treatment of co-occurring conditions in primary care.
Psychologists at Cardiff University developed a reliable adult self-assessment test to measure repetitive behaviors in autism. Adults with an autism diagnosis consistently scored higher on this measure than those without an autism diagnosis, highlighting its potential as a diagnostic tool.
The Interactive Autism Network (IAN) has been awarded $1.6 million by the Patient-Centered Outcomes Research Institute (PCORI) to join PCORnet, a national health research resource. IAN will collaborate with researchers, patient communities, and clinicians to accelerate autism research and improve patient outcomes.
A study by researchers at UCLA found that a social skills program for high-functioning young adults with autism improved their ability to engage with peers. The gains persisted 16 weeks after the program ended and were accompanied by increased empathy and greater responsibility.
A study analyzing special education data found that autism diagnoses increased, but so did reclassifications of intellectual disability cases. Researchers believe this shift may be attributed to the variability of autism and its overlap with other related disorders.
A new study reveals that young people with autism are struggling to find and keep jobs, with only 47% securing employment after receiving vocational services. Experts emphasize the importance of vocational counseling, guidance, and coordination between high schools and rehabilitation systems to support this growing population.
Researchers at Yale School of Medicine have developed a stem cell study that could help predict autism spectrum disorder and identify new drug targets. The study used skin cells to generate simulated brain organoids, revealing gene expression and developmental abnormalities in autism.
Researchers have discovered a key mechanism behind brain growth abnormalities in individuals with autism spectrum disorder, revealing how PTEN gene mutations alter the trajectory of early brain development. Excess glia cells and changes in β-Catenin signaling contribute to the observed brain overgrowth.
Individuals with autism spectrum disorders often exhibit poor nutrition due to selective eating patterns and sensory sensitivity. Early warning signs include lower folate, vitamin B-6, and vitamin B-12 concentrations, as well as abnormally accelerated growth rates in infants and children.
Researchers discovered that children with autism spectrum disorder exhibit a unique sniffing pattern when exposed to pleasant or unpleasant odors, allowing for accurate classification with high accuracy. The study suggests that olfactory tests could be used as an early indicator of ASD, potentially leading to more effective intervention.
A small study found that premature babies who avoid eye contact in early infancy are less likely to display symptoms of autism at age 2 compared to those who maintain eye contact. The researchers suggest that preemies may avert their gazes as a coping mechanism, signaling an inability to handle stressors.
A study examining cesarean section delivery and autism spectrum disorder found an initial association between the two, but further analysis of sibling pairs revealed no causal link. The study suggests that unknown genetic or environmental factors may contribute to the increased risk of both cesarean section and autism spectrum disorder.
Researchers have discovered that infants with superior perception skills are more likely to develop autism symptoms later in life. The study found that enhanced visual searching ability at 9 months old predicted more emergent autism symptoms at 15 months and 2 years of age.
A UCLA study finds that children with autism spectrum disorder who are overly sensitive to sensory stimuli have brains that react differently, leading to a condition called sensory over-responsivity. The research may lead to interventions that can help improve the lives of these children and their families.
A new study shows that early intensive autism intervention can lead to improved intellectual ability and reduced autism symptoms in young children. The therapy, known as the Early Start Denver Model, was found to be particularly effective in promoting social and communication skills.
A recent study published in Molecular Psychiatry found a significant increase in autism rates among children born to teenage mothers and parents with large age gaps. The research also confirmed that older parents are at higher risk of having children with autism.
Researchers at Salk Institute found that a low glycemic index diet reduced symptoms of autism in mice, including impaired social interactions and repetitive behaviors. The diet may influence gut bacteria and inflammation, which are linked to the development of autism.
Researchers found that boys with autism exhibit higher levels of stereotyped behaviors and cognitive difficulties than girls, but these sex differences also appear in children without ASD. The study suggests naturally occurring sex differences in all children may contribute to the observed sex differences in autism.
A new study reveals that social and sensory overstimulation is the primary driver of autistic behaviors, contradicting decades-old views of autism as a mental retardation. The research proposes that autistic brains are hyper-functional, requiring predictable and structured environments to function optimally.
A new NIH grant will help researchers at SDSU study brain connections and cognitive abilities in older adults with autism. This is a significant step towards understanding how autism affects individuals across the lifespan.
A study by Penn State researchers reveals that 64% of children initially diagnosed with autism also have apraxia, a rare neurological speech disorder. The Checklist for Autism Spectrum Disorder (CASD) accurately diagnoses autism in children with apraxia, and ongoing screenings are crucial to prevent long-term problems.
A new study by GW researcher Valerie Hu found significant sex-dependent differences in brain RORA protein levels, with males having lower baseline levels and stronger correlations with genes regulated by RORA. The findings suggest that RORA deficiency may contribute to the known male bias in autism susceptibility.
Researchers used a 3D simulator to test how individuals with Autism Spectrum Disorder process sensory stimuli. Contrary to previous theories, the study found that autistic participants demonstrated intact multi-sensory integration in both coherent and noisy environments.
New research reveals differences in the brains of girls and boys with autism, particularly in the corpus callosum and social impairments. The study suggests that girls with autism have more severe social impairments than boys, highlighting the need for targeted research and interventions.
Research published in Molecular Autism found that male toddlers with autism have distinct brain structure changes compared to females, suggesting separate evaluation and early developmental markers. Additionally, studies suggest a 'female protective effect' through sex differences in genes and prenatal hormones.
Researchers found that genetic mutations passed from mothers to sons are more likely to increase autism risk. The study provides a comprehensive genetic picture of autism and may lead to the discovery of biomarkers for diagnosis and targeted treatments.
Researchers from USC and CHLA found that adapting dental environments to be more calming for children with autism spectrum disorder significantly reduced psychological anxiety and pain intensity. The study used sensory adaptations such as soothing music, gentle lighting, and deep-pressure hugs to create a comfortable environment.
The 2015 Weatherstone Predoctoral Fellowship class of Autism Speaks will pursue two-year research projects under mentorship of leading scientists. The program aims to advance understanding of autism and support essential training opportunities for the brightest young investigators.
Researchers discovered that parents of children at high risk for autism spectrum disorder reported more early concerns, particularly sensory and motor issues starting at six months. Early parental concerns can be predictive of autism diagnosis, highlighting the importance of talking to parents and taking their concerns seriously.
A comprehensive report by Drexel University's A.J. Drexel Autism Institute highlights poor life outcomes for young adults on the autism spectrum, including high disconnection rates, limited employment and education opportunities, and increased health risks.
A multi-site study found that parent training reduced disruptive behavior by 48% compared to 32% for parent education. Parent training provided specific strategies for managing serious behavioral problems such as tantrums and aggression.
A new study published in Biological Psychiatry found no genome-wide significant associations between genetic variants and autism spectrum disorder. Instead, the researchers suggest that clinical variability in autism may be due to factors such as epigenetic changes or environmental responses. The study's results have implications for f...
Recent breakthroughs in autism spectrum disorder (ASD) research focus on precision medicine approaches, leveraging genetic technologies to identify risk genes and develop personalized therapies. Neuroimaging studies are also helping understand brain structure and function across the lifespan.
A small study found distinct patterns of regulatory tags in DNA from fathers' sperm linked to children's early signs of autism. The presence or absence of these tags was statistically related to Autism Observation Scale for Infants scores, suggesting a potential contribution to the condition.
A new Kaiser Permanente study found that children whose mothers developed gestational diabetes by the 26th week of pregnancy had a 63% increased risk of being diagnosed with an autism spectrum disorder. The study also found that early screening for autism in children of women with gestational diabetes may be warranted.
A study from the University of Missouri found that violent video games do not affect adults with autism spectrum disorder differently than typically developing adults. Over 100 participants, half with autism and half without, showed similar aggression levels after playing violent or nonviolent games for 15 minutes.
A Johns Hopkins-led team of researchers has identified a rare genetic cause of autism, which may also be linked to other complex genetic conditions. The study used a novel approach that focused on families severely affected by autism to pinpoint the CTNND2 gene as a potential culprit.
A child with autism improved dramatically while taking an antibiotic for strep throat, prompting a quest by the parent to understand the phenomenon. The collaboration led to a scientific conference and special issue in a scientific journal featuring articles on the microbiome's involvement in autism.
A recent study suggests a link between genes linked with autism and higher intelligence in individuals who do not have the condition. Researchers found that carrying genetic traits associated with autism is, on average, linked to slightly better cognitive test scores, even in those without autism.
A UK twin study found that genetics account for up to 95% of the risk of developing autism spectrum disorder, with moderate environmental influences also playing a role. The study's results provide new insights into the complex causes of autism and may help inform future treatments.
A clinical trial funded by Autism Speaks' DELSIA will test a cognitive video game designed to improve executive function skills in children and adolescents with autism. The study aims to assess the effectiveness of the game, Project: EVO, in improving brain function and motor skills.
A study published in Genes, Brain and Behavior found that animal models with autism risk gene mutations exhibit decreased aggressive behavior towards strangers, instead engaging in repetitive patterns. The research suggests a potential counter-narrative to the widespread perception of increased aggression in individuals with autism.
A growth hormone called IGF-1 has been shown to improve social impairment and restrictive behaviors in children with Phelan-McDermid syndrome, a disorder associated with autism. The treatment showed significant improvement in social withdrawal and repetitive behaviors compared to placebo.
Researchers from Marcus Autism Center found intensive behavioral intervention to be effective in eliminating pica in children with autism spectrum disorder. The treatment involved blocking inappropriate eating, redirecting behavior, and rewarding disposal of non-edible objects, resulting in a 96% reduction in pica in most cases.
A research collaboration found that induced or augmented labor does not increase the risk of children developing autism spectrum disorder. The study, which analyzed data from over 167,000 births, suggests that labor induction or augmentation is safe for mothers and babies.
A recent study published in JAACAP found that abandoned children placed in institutions have an increased risk for behaviors similar to those seen in children with autism. However, when moved into child-centered foster family care at a young age, their social behaviors improved significantly.
A recent study published in the Society for Maternal-Fetal Medicine's annual meeting found that induced or augmented labor is not associated with an increased risk of Autism spectrum disorder. The research analyzed data from over 166,000 children and found no link between labor induction/augmentation and ASD diagnosis.
A recent study of 340 whole genomes from 85 families with two children affected by autism found that most siblings share different autism-linked genes. The research, led by Stephen Scherer, provides new insights into the complex genetic underpinnings of autism and suggests that each child with autism is unique.
A new project at the University of Washington is working to ensure that children with autism are identified and helped early enough to prevent problems later on. The initiative uses a Web-based screening system and simple play-based interventions to identify and treat toddlers at risk for autism.
New research published in The Lancet Psychiatry suggests that video-based therapy can modify the emergence of autism-related behaviors and symptoms in infants at risk of autism. The therapy showed improvements in infant engagement, attention, and social behavior, with a moderate effect on reducing some children's risk of autism.
Advanced 3D facial imaging may aid in early detection of autism. Researchers identified three distinct subgroups of children with autism who had similar measurement patterns in their facial features.
Researchers at Virginia Tech Carilion Research Institute have developed a brain-imaging technique that can detect autism spectrum disorder in children. The test, which involves measuring perspective-tracking responses, has shown promising diagnostic potential and may revolutionize the way autism is diagnosed.