Children who spend a significant amount of time on social media platforms experience a gradual decline in their ability to concentrate. The study found no association between TV watching or video game playing and attention symptoms.
A new study by researchers at Karolinska Institutet found that lower doses of approved immunotherapy drugs can give better results against tumours, while reducing side effects. The regimen with the lower dose of ipilimumab was more effective, with a higher proportion of patients responding to treatment and longer overall survival.
Researchers at Karolinska Institutet have discovered that specific DNA sequences, known as enhancers, are activated after spinal cord injury and instruct cells to respond. This knowledge could lead to more precise treatments targeting the affected cells, revolutionizing the treatment of spinal cord injuries.
A nationwide observational study from SWEDEHEART reveals that patients with type 1 diabetes have a significantly higher risk of stent complications compared to those without diabetes. The study emphasizes the need for adapted treatment and follow-up strategies for this patient group.
A new study identifies a brain circuit that can drive repetitive and compulsive behaviors in mice, even when natural rewards are available. The researchers used optogenetics to activate the circuit and induce negative states in mice, leading to prioritization of repetitive behaviors over natural needs.
A recent study published in Nature Genetics found that depression beginning before age 25 has a stronger hereditary component and is associated with a higher risk of suicide attempts. The research identified 12 genetic regions linked to early-onset depression, highlighting the potential for precision medicine in psychiatry.
A new study reveals that sons born to mothers with type 1 diabetes show early signs of vascular dysfunction in their blood vessels, even before metabolic health is affected. The research suggests that this sex-specific effect could help clinicians assess risk and prevent cardiovascular disease earlier in life.
A recent study from Karolinska Institutet has identified a specific protein pattern in the blood that may reflect an increased risk of hereditary atherosclerosis. The research found that certain proteins, such as follistatin and cathepsin D, are significantly elevated in people with a family history of early-onset coronary heart disease.
Researchers created a multidimensional molecular map of brain development after birth and its response to inflammation, finding that some developmental programmes can be reactivated during neuroinflammation. This study provides new clues for understanding how myelin is broken down in diseases like MS.
A nationwide study found that involuntary psychiatric patients have a significantly higher risk of suicide, particularly during the first month after discharge. The risk is elevated for several years and is associated with factors such as age, diagnosis, and previous self-harm.
Researchers at Karolinska Institutet identified four distinct subgroups of PCOS, showing clear differences in pregnancy rates and metabolic complications. These findings could lead to more tailored treatments for women with the disease.
Researchers found a genetic variant that protects against winter vomiting disease, which was introduced to Europe through early farmers around 6,000 BCE. The FUT2 gene variant is linked to an increased risk of stomach ulcers and gallstones, but provides full protection against the virus.
A new study from Karolinska Institutet found that countries with higher human development indices and lower gender inequality have higher levels of cardiorespiratory fitness among young adults. Women's VO2peak was significantly higher in countries with high gender equality compared to those with low gender equality.
Researchers at Karolinska Institutet have developed a system to classify individuals into different risk groups for atherosclerosis based on genetic data. The study identified four distinct risk groups, with one specific gene variant linked to increased cardiovascular risk in those with high predicted risk.
A new study from Karolinska Institutet and UCL found that living in a safe neighborhood with high personal trust reduces psychosis risk among Swedish or European origin residents, but increases it for North African or Middle Eastern origin individuals. The researchers emphasize the need for inclusive environments to promote mental heal...
A new study from Karolinska Institutet reveals that postural orthostatic tachycardia syndrome (POTS) affects nearly a third of patients with severe long COVID, with middle-aged women being the most common demographic. Researchers emphasize that POTS can be detected with simple tests and treated to alleviate symptoms.
A study of 27,500 people found that poor sleep leads to brains appearing older than their actual age. Low-grade inflammation is estimated to explain around 10% of the link between poor sleep and older brain age.
A recent study from Karolinska Institutet reveals how a gene associated with several rheumatic diseases affects cell movement. The researchers discovered that the DIORA1 gene regulates cell movement by interacting with MRCK kinases, which are important for the cell's skeleton and ability to move.
A simple blood analysis can predict the risk of developing severe liver disease, enabling earlier detection and potentially improving treatment outcomes. The CORE model, developed by Karolinska Institutet researchers, is based on three routine blood tests and has been shown to be highly accurate in predicting liver disease risk.
New studies from Karolinska Institutet show that mental health issues during pregnancy and postpartum can lead to long-term consequences, including depression and psychosis. The risk of these conditions increases significantly after childbirth.
A new study from Karolinska Institutet reveals that women who skip their first mammogram are more likely to be diagnosed with advanced breast cancer and die from the disease. The study found a 32% decline rate among women who missed their first screening, leading to poorer prognosis and higher mortality rates.
A study published in Journal of Internal Medicine found that people with moderate to high levels of albumin in their urine have a higher risk of developing dementia. The researchers discovered an association between albuminuria and increased risk of dementia, independent of kidney function.
A new study from Karolinska Institutet found that music training strengthens the brain's ability to focus under distracting conditions. Musical people were better at using top-down attention while being less sensitive to bottom-up distractions.
A randomized clinical trial shows that low-dose aspirin reduces the risk of recurrence by 55% in patients with colon and rectal cancer harboring a specific genetic mutation. Aspirin's anti-inflammatory and anti-tumor effects may be responsible for its therapeutic benefits.
A new study reveals that the brain integrates signals from taste and smell earlier than thought, activating the same parts of the brain's taste cortex. This overlap suggests a shared neural code for flavour experiences, which may influence our eating habits and preferences.
A comprehensive registry study in Sweden found that healthy, full-term babies under three months old are at risk of severe illness from RSV. The study highlights several risk factors, including birth weight and sibling age, which increase the risk of needing intensive care or dying.
A recent study published in Journal of Adolescent Health found that young people from diverse cultures worldwide perceive digital environments as affecting their mental health. They highlight the need for more support and involvement from adults in their digital lives, including reflection on one's own digital habits.
Two new studies from Karolinska Institutet investigate how somatic mutations in muscles and blood vessels affect ageing. The results show that such mutations can reduce muscle strength and accelerate blood vessel ageing.
A comprehensive epidemiological study found that people who had COVID-19 are at increased risk of developing certain inflammatory diseases of the airways, such as asthma and chronic sinusitis. Vaccination against SARS-CoV-2 virus appears to reduce this risk.
A nationwide Swedish study found nearly three times as many young adults under 50 diagnosed with colorectal cancer today compared to the early 1990s. The disease has become two to three times more common in this age group, with underlying causes not fully understood.
A comprehensive genetic analysis of nearly one million participants found hundreds of genetic markers influencing frailty risk. The study reveals frailty is not caused by a single factor but by multiple genes affecting the immune system, brain, and metabolism.
A new study from Karolinska Institutet found that centenarians tend to accumulate diseases at a slower rate compared to non-centenarians. The study showed that centenarians are less likely to develop multiple diseases simultaneously, and those diseases often occur later in life.
A new study from Karolinska Institutet shows that healthy diets can slow down the accumulation of chronic diseases in older adults, while inflammatory diets accelerate it. Researchers followed over 2,400 older adults for 15 years and found those on healthy diets had a slower development of cardiovascular disease and dementia.
Researchers identified over 250 proteins that change during malaria infection, enabling patients to be grouped according to severity. This allows for quicker identification of high-risk patients and more effective treatment.
A new study from Karolinska Institutet has found that women with premenstrual symptoms are at a higher risk of developing cardiovascular disease. The study, which followed over 99,000 women for up to 22 years, revealed a significant link between premenstrual symptoms and an increased risk of heart rhythm disorders and stroke.
Researchers identified TMEM9B-AS1, a long non-coding RNA that regulates cellular functions, as significantly reduced in skeletal muscles of people with type 2 diabetes. Its absence disrupts protein production, leading to muscle weakness and loss.
A new study from Karolinska Institutet found that adults who have survived childhood cancer are 58% more likely to develop severe COVID-19 if they contract the virus. Despite having a lower risk of infection, childhood cancer survivors experienced more serious consequences when they did become ill.
A study published in The International Journal of Cancer found that children born by planned C-section have a higher risk of developing acute lymphoblastic leukaemia (ALL) later in life. The risk was 21% higher in children born by planned C-section compared to those born vaginally.
Researchers from Karolinska Institutet have identified proliferating neural progenitors in the adult human hippocampus, confirming ongoing neuron formation. This discovery has implications for understanding brain changes during life and developing regenerative treatments for neurodegenerative and psychiatric disorders.
A study by Karolinska Institutet found that an AI tool improved pathologists' assessments of tissue samples from skin cancer tumours, leading to more consistent results and better prognoses. The tool helped quantify tumor-infiltrating lymphocytes, a biomarker in several cancers, including malignant melanoma.
A new study conducted at Karolinska Institutet reports that gene therapy improved hearing in all ten patients with congenital deafness or severe hearing impairment. The treatment was well-tolerated and showed remarkable results, with the majority of patients recovering some hearing after just one month.
A new study from Karolinska Institutet found that biological drugs used to treat severe asthma do not completely eradicate inflammatory cells. Researchers discovered an increase in blood levels of these cells during treatment, which could explain why inflammation often returns when treatment is tapered or discontinued. The study aims t...
A new potential drug treatment has shown promising results in reducing blood sugar levels and increasing fat burning in people with type 2 diabetes and obesity. The treatment activates metabolism in skeletal muscle, promoting healthy weight loss and preserving muscle mass, a key factor in metabolic health.
A new study from Karolinska Institutet found that infants who survive serious health problems in the first few weeks of life have a higher risk of dying during childhood and adolescence. Children with neurological health problems had almost six times the risk of death compared to healthy children.
Researchers at Karolinska Institutet found that a Western diet can cause long-lasting damage to the blood vessels of pancreatic islets, leading to impaired glucose metabolism. The study's findings highlight the importance of preserving islet vascular health in metabolic diseases.
A large-scale study from Karolinska Institutet reports that individuals with an autism diagnosis are four times more likely to develop early-onset Parkinson's disease. The researchers believe that shared underlying biological mechanisms may be at play, particularly involving the neurotransmitter dopamine.
An international team of researchers has identified a genetic link to long-term symptoms after COVID-19, with a gene variant increasing the risk by about 60%. The variant is located near the FOXP4 gene, which affects lung function and development. Impaired lung function plays a key role in developing long COVID.
A new study from Karolinska Institutet found that combining air pollution, dense urban development, and limited green spaces increases the risk of asthma. In contrast, a more favorable environment can prevent up to 11.6% of asthma cases, suggesting that urban planning can play a crucial role in reducing the disease.
A new study found that adults diagnosed with type 1 diabetes after age 40 have a higher risk of cardiovascular disease and death compared to those diagnosed earlier. Poor glucose control, obesity, and smoking are the main risk factors identified in the study.
Pregnant women with fatty liver disease are at an increased risk of giving birth prematurely, with a threefold higher risk compared to the general population. The study also found that women with fatty liver disease had a 63% higher risk of caesarean section.