A new study shows that while dental opioid prescription fills in the US have dropped by 27% since 2021, the rate remains higher than in other developed countries and the US territory of Puerto Rico. The study suggests that some US dentists are still overprescribing opioids.
A national study found that people with severe strokes have a five times higher odds of developing dementia. Stroke severity also affects thinking and memory after stroke, highlighting the need for close monitoring and treatment of dementia risk factors.
Researchers found distinct gut microbiome characteristics that predicted treatment response to the low FODMAP diet and rifaximin. Patients who responded to these treatments had different microbial signatures, with increases in diversity for those on the low FODMAP diet and resilience against antibiotics for those on rifaximin.
A national poll suggests that one in three parents report their young adult children are minimally active or inactive, with lack of interest and screen time being major barriers. Parents often try to encourage physical activity through verbal encouragement, activities, and exercising together, but many efforts are not successful.
A new study found that pregnancy-related deaths increased sharply during the pandemic, particularly among Black women, but rates have since returned to pre-pandemic levels for most groups. However, disparities persist, especially in later postpartum deaths, which remain elevated for non-Hispanic Black mothers.
A new University of Michigan-led research has identified a connection between keratin 16 and type 1 interferon in the molecular pathways of pachyonychia congenita. The study found that losing or altering K16 causes amplification of the inflammatory response, but also helps pump the brakes on that response.
People aged 50 and over who serve as unpaid family caregivers are more likely to support government-funded care, while non-caregivers prefer family or older adult payment. Concerns about long-term care costs and access persist among caregivers versus non-caregivers.
A new study identified PIKfyve as a promising therapeutic target for gastroenteropancreatic neuroendocrine tumors (GEP-NETs), leading to longer survival in mouse models. By targeting two separate pathways that control lipid synthesis, the researchers found that inhibiting PIKfyve reduced tumor volume and weight compared to controls.
A new study identified two enzymes, glucose-6-phosphate dehydrogenase and malic enzyme 1, that can influence metabolic changes in pancreatic cells. Decreased activity of these enzymes results in increased reactive oxygen species, leading to precancerous lesion formation.
Researchers have developed copper-loaded starch nanoparticles that can be broken down by specific bacteria to release antibacterial copper molecules. These nanoparticles were effective against Staphylococcus aureus and Bacillus subtilis, with improved targeting capabilities compared to previous studies.
A web-based platform, GIFT, educates people with cancer about the impact of genetic variants on their family. The tool allows patients to invite relatives and provides information, decision support, and access to genetic testing.
A new poll finds that nearly a third of Americans over 50 provide regular care to an adult relative or friend with a health issue or disability, highlighting the need for increased awareness of existing programs such as adult day programs and respite care. Many caregivers face financial stress and don't know about or use these resource...
A new study from Michigan Medicine found that over 7% of Americans have thought about shooting someone, while 8.7 million adults considered it in the last year. Firearm owners were no more likely to have these thoughts than non-owners, but 21% of those who had thoughts said they would consider giving their gun to someone for safekeeping.
A new pediatric mental health care model, P2C3, combines primary care and psychiatry to improve access and training for future pediatricians. The model, which has completed over 1,500 visits and cared for over 400 patients, has shown durable and scalable results, reducing fragmentation and providing timely access to mental health care.
A national poll finds 1 in 3 parents worry their teen or young adult driver could cause an accident, with most witnessing unsafe driving behaviors. Despite concerns, most parents rate their child's driving as average or better, and relatively few impose consequences for risky behaviors.
Researchers found that fedratinib inhibits BRD4, activating a transcriptional pathway that induces ERMCS formation and causes structural changes in organelles. The study provides a potential therapeutic avenue for diseases like neurodegeneration, obesity, and cancer.
Researchers from Michigan Medicine discovered that photoreceptor cell death is reversible and can be rescued by removing damaged mitochondria. The study found that mitophagy, a process that removes dysfunctional mitochondria, plays a crucial role in this recovery process.
Researchers discovered that 53% of newborns with myelomeningocele had sleep-disordered breathing, highlighting the need for routine screening and early intervention to prevent long-term complications. The study's findings suggest that addressing sleep disorders in high-risk infants could meaningfully improve their neurodevelopment.
Researchers found that glucose levels sustain increased STAT3 activation in colorectal cancer cells. Targeting glucose metabolism could inhibit STAT3 and lead to novel therapeutic strategies.
Seq-Scope-eXpanded allows researchers to see even finer transcription detail, enabling discoveries that weren't possible with previous methods. The technology has been expanded to capture transcriptome from tissue with greater resolution.
A new poll finds that pets contribute to healthy aging benefits for older adults, including increased sense of purpose and reduced stress. However, 31% of pet owners aged 50+ report that owning a pet strains their budget, mainly due to financial costs.
A national poll found that nearly half of parents are aware of the risk of sudden cardiac arrest in teens, but only about half know their school has an automated external defibrillator (AED) on site. Parents support CPR and AED training, with four in 10 already trained to use an AED, and nearly nine in 10 willing to receive free training.
Researchers used AI to analyze RNA sequences from patients with antiphospholipid syndrome (APS), uncovering four distinct molecular patterns or 'endotypes' that drive disease. These patterns suggest different immune system behaviors and may require tailored treatments, offering a more personalized approach to APS care.
A new AI-powered model can read a brain MRI and diagnose neurological conditions with up to 97.5% accuracy, predicting treatment urgency and automating alerts for immediate medical attention. The technology has the potential to transform neuroimaging at health systems across the US, reducing workload and improving patient outcomes.
A machine learning model identified 17 environmental and social factors that contribute to out-of-hospital cardiac arrests. Mean ambient temperature and higher relative humidity are associated with an increase in OHCA incidents.
A recent poll found that 42% of people over 50 haven't gotten either flu or COVID-19 vaccines in the past six months. The leading reason for not getting vaccinated was a lack of perceived need, despite clear evidence showing vaccination reduces the risk of serious illness and death in older adults.
The Ann Arbor Guide provides two algorithms for triaging adults with suspected UTIs, one for non-pregnant women and the other for men. It also emphasizes the importance of accurate testing and treatment to prevent overuse of antibiotics and antibiotic resistance.
Researchers developed a novel tool, CytoTape, to record temporal cell activities in situ along a flexible intracellular protein fiber. This technology enables scientists to view interactions on a large scale and over long periods of time, breaking through the tradeoff between resolution and scale.
A pilot study found that long-term exposure to higher pollen levels leads to worse symptoms and quality of life for patients with chronic rhinosinusitis. Higher ragweed pollen exposure correlated with worse Sino-Nasal Outcome Test scores.
A new study finds that hospitals treating more patients with Medicare Advantage plans face higher readmission penalties despite taking similar actions to prevent repeat hospitalizations. The analysis highlights the need to incorporate Medicare Advantage data into the Hospital Readmissions Reduction Program.
A new study suggests that gaps in the nation's stroke transfer system reduce survivors' chances of receiving critical treatment and increase disability. Patients with longer delays in hospital transfer experienced worse disability after their stroke, highlighting missed opportunities for many stroke patients.
A statewide partnership in Michigan led to a significant increase in patients receiving follow-up imaging after aortic aneurysm repair. This resulted in a reduced likelihood of dying within one year of surgery and improved detection of early problems that can lead to device failure or future complications.
A national poll found that only half of parents believe children should never swear, with many acknowledging their own kids' occasional use of curse words. Peers are the top source of profanity, followed by popular media and home language.
Researchers developed a model that can predict long-term prostate cancer mortality risk using PSA scores, helping doctors and patients make informed decisions about further screening and treatment. The model was tested on over 200,000 patients and showed improved accuracy compared to existing risk calculators.
A recent University of Michigan study analyzed over 60 million Medicare participants and found that total visits remained stable or declined slightly through June 2024. Despite widespread adoption of telehealth, overall healthcare visits stayed steady or decreased, contradicting predictions of increased utilization.
A study analyzing 218.1 million notes from 1.6 million patients found 372 emojis in 4,162 notes between 2020 and 2025, with smileys/emoticons being the most common type used.
Researchers have uncovered the critical function of occludin in regulating cell barriers, particularly in diabetic retinopathy. The study revealed that occludin's alternative splicing produces a form of occludin that controls leaky blood vessels and excessive vessel growth.
Researchers found that over half of IVF cycles in the US were performed at clinics affiliated with private equity firms, sparking concerns about the impact on quality and accessibility. The study's authors emphasize the need for further research to understand the benefits and risks of this business model.
Researchers developed a microfluidic device to capture biomarkers released by tumor cells in glioblastoma patients. The device detected specific proteins associated with the disease and predicted patient responses to chemotherapy, improving treatment outcomes.
Researchers discovered a new protein target and developed a drug to treat non-small cell lung cancers with KRAS mutations. The molecular glue RPT04402 stabilizes the protein phosphatase 2A complex, leading to cancer cell death and delaying resistance to therapies.
Researchers developed an AI model that can detect coronary microvascular dysfunction using a common electrocardiogram, outperforming previous models in diagnostic tasks. The model can accurately identify a condition often missed in emergency department visits, providing a cost-effective and non-invasive way to diagnose serious heart co...
A national poll reveals that many parents struggle to provide guidance on healthy eating habits for their teens, particularly during the holiday season. The poll found that only half of parents report their teen eats three meals a day, and nearly a third report their teen snacks throughout the day.
A study published by Michigan Medicine suggests that AI can help increase the chance of people with risky drinking patterns or signs of alcohol use disorder getting outreach and help. The NLP tool analyzed full text of health records and identified over 47,500 patients with some sign of risky drinking.
A study from Michigan Medicine found that only 24% of public insurance patients and 30% of private insurance patients received primary care follow-up within one week of ICU discharge. Younger, healthier children were more likely to receive timely care. The lack of guidance led researchers to investigate this issue.
Scientists at Michigan Medicine have developed machine learning models that can analyze blood samples for biomarkers to detect ALS earlier and predict disease severity. The models show promising results, with predictions accurate up to 91% in some cases, and could lead to improved diagnostic accuracy and treatment options.
A new study suggests that prevention campaigns for cannabis-related vehicle crashes should target middle-aged and older adults, who are at risk of driving after using the drug. Adults over 50 who use cannabis daily or have mental health reasons are most likely to drive after using THC-containing products.
The new guideline recommends full-time infection prevention staff, comprehensive training, and support for all staff, as well as partnerships with hospitals and public health agencies. This guidance aims to reduce the risk of infections in nursing homes, saving lives and money.
A new study from Michigan Medicine found that its data-driven command center increased hospital bed use efficiency by 63%, reducing emergency department boarding time by 33% and patient transfers by 13%. The initiative also streamlined discharge processes, resulting in a 12% drop in waiting times for patients ready to leave the hospital.
A new poll suggests that more than 80% of people over 65 drive at least weekly, but less than half have made a plan for when they can no longer drive safely due to health changes. Only 6% of older drivers have discussed their driving with a healthcare provider.
A recent University of Michigan study sheds light on the critical protein Sarm1, which controls both nerve breakdown and regeneration. The research found that blocking Sarm1 boosts nerve regeneration but only if it preserves a delicate balance between protection and repair.