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Regenstrief Institute


Helping the Helpers: Leveraging information technology to support caregiver medication management for the millions of individuals who live with dementia

Researchers developed an evidence-based app to support caregivers in managing complex medication regimens for individuals with dementia. The Helping the Helpers app leverages virtual component and participatory co-design with caregivers to address significant caregiver burden, stress, and potential mistakes.

SourceRegenstrief Institute·JournalResearch in Social and Administrative Pharmacy·DateJun 14, 2022

Regenstrief and Indiana University study explores eating, drinking, and physical activity among middle aged women living with obesity and urban poverty

Researchers analyzed mobile app data to gain insight into behaviors of middle-aged women living with severe obesity in urban poverty. The study found associations between anxiety and weight loss or gain, as well as correlations between location, timing, and eating/drinking frequency.

SourceRegenstrief Institute·JournalObesity Science & Practice·DateMay 25, 2022

Patient safety and quality of care: Regenstrief study explores medical record linkage with goal of improving match accuracy

A new Regenstrief Institute study evaluates commercially available matching methodologies against real-world gold standard data to identify opportunities for improving match accuracy. The study found that referential patient matching demonstrates greater sensitivity and accuracy than traditional probabilistic approach.

SourceRegenstrief Institute·JournalJournal of the American Medical Informatics Association·DateMay 19, 2022

The double-edged sword of clinical texting: Study explores improving patient care via more effective clinician communication

A new study from the Regenstrief Institute examines the effects of clinical texting on hospitalist and nurse communication, highlighting both benefits and challenges. The study suggests that clinical texting can improve communication, but also raises concerns about user buy-in and shared understanding.

SourceRegenstrief Institute·JournalApplied Clinical Informatics·DateMay 10, 2022

Depression detection has never been more important: PHQ-9 enables clinicians and patients to track and address depression with combined physical and emotion symptoms score

A large international study found that PHQ-9 accurately indicates the presence and severity of depression, regardless of sex, age, or language. The tool enables clinicians and patients to track and address depression by measuring both physical and emotional symptoms.

SourceRegenstrief Institute·JournalPsychological Assessment·DateMay 2, 2022

New data shows burden of dementia symptoms just as high in community population as nursing home residents

Researchers found that people with advanced Alzheimer’s disease and related dementias who live in the community experience similar symptom burdens to those in nursing homes. The study suggests that palliative care interventions could ease symptom burden and improve quality of life for patients and caregivers.

SourceRegenstrief Institute·JournalJournal of Palliative Medicine·DateApr 27, 2022

Regenstrief informaticians identify golden opportunities for improving delivery of preventive care and monitoring of acute and chronic conditions

Researchers propose that well-designed computerized clinical decision support can facilitate team approaches to healthcare, enhancing communication and coordinating group effort. The tool provides evidence-based information and guidance, enabling primary care physicians to oversee a diverse healthcare team more efficiently.

As number of ICU survivors increase, study validates first tool to utilize caregiver input to assess post-ICU syndrome symptoms

A new study validates the Healthy Aging Brain Care Monitor as an accurate tool for monitoring post-intensive care unit (ICU) symptoms among ICU survivors through caregiver input. The tool assesses both patient and caregiver burden, providing clinically relevant information on physical, mental, and emotional symptoms.

SourceRegenstrief Institute·JournalAmerican Journal of Critical Care·DateApr 6, 2022

Innovative AI technology aids personalized care for diabetes patients needing complex drug treatment

Researchers developed an AI method to analyze electronic health record data and predict optimal drug regimens for type 2 diabetes patients with similar characteristics. The algorithm successfully supported medication selection for over 83% of patients, leading to better management of the disease and improved patient engagement.

SourceRegenstrief Institute·JournalJournal of Biomedical Informatics·DateMar 25, 2022

Addressing healthcare needs of transgender adults: Qualitative study finds three main barriers to receiving primary care in a supportive environment

A qualitative study explores healthcare experiences of transgender patients in Indiana and reveals three major barriers: finding an affirming provider, navigating wait times, and feeling comfortable in care settings. The research highlights the need for primary care providers knowledgeable about transgender health and safe spaces to ad...

SourceRegenstrief Institute·JournalJournal of General Internal Medicine·DateMar 7, 2022

Prioritized supportive care needs of patients and caregivers during active cancer treatment

A new study from Regenstrief Institute identifies divergent priorities among cancer patients and their caregivers during active treatment, with patients focusing on physical issues like pain and caregivers prioritizing social support. The research emphasizes the need for enhanced whole-family approaches to supportive oncology care deli...

SourceRegenstrief Institute·JournalJCO Oncology Practice·DateFeb 1, 2022

Local policy matters when it comes to public health

A new study from Regenstrief Institute found that local mask policies have a strong impact on mask-wearing behavior in public places. The research team observed 76,000 people at various locations and found that most people wore masks even after the state lifted its mandate.

SourceRegenstrief Institute·JournalJournal of Public Health Management and Practice·DateJan 24, 2022

Data can help address health disparities

A local health department in Indiana used surveillance data to identify neighborhoods with high disease burden and set up test sites, resulting in a decline in new cases among targeted groups. The success of this intervention highlights the importance of using data to address systemic racism and promote health equity.

SourceRegenstrief Institute·JournalAmerican Journal of Public Health·DateDec 2, 2021

Study tackles reducing bladder cancer recurrence

A new study by the Regenstrief Institute found that lack of protocols or standard operating procedures in the recovery room is a significant barrier to administering post-operative chemotherapy to reduce bladder cancer recurrence. The researchers identified 58 Michigan urologists who reported this as a major obstacle, emphasizing the n...

SourceRegenstrief Institute·JournalThe Journal of Urology·DateNov 16, 2021

Vaccines effective against Delta variant

A national study found COVID-19 vaccines are effective in preventing hospitalizations and emergency department visits caused by the Delta variant. The Moderna vaccine is significantly more effective than Pfizer and Johnson & Johnson, with unvaccinated individuals being 5-7 times more likely to need emergency care or hospitalization.

SourceRegenstrief Institute·JournalMMWR Morbidity and Mortality Weekly Report·TypeData/statistical analysis·DateSep 10, 2021

COVID-19 vaccines are highly effective in preventing hospitalizations, emergency visits

A New England Journal of Medicine study found that COVID-19 vaccines are highly effective in preventing hospitalizations, emergency department visits, and intensive care admissions due to the virus. The vaccines provide significant protections for older adults and minorities, who have been disproportionately affected by the virus.

SourceRegenstrief Institute·JournalNew England Journal of Medicine·TypeData/statistical analysis·DateSep 9, 2021