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University of Pittsburgh


Uncovering patterns amid chaos

A recent NSF grant will support the development of new diagnostics and predictive models for understanding self-competition and weak asymmetry in turbulent flows. The project aims to uncover hidden patterns that current models miss, leading to improved simulations in weather forecasting, climate modeling, and engineering design.

An open source breakthrough in hemodynamics

Researchers have developed an open-source pressure myography tool, HemoLens, which reduces the cost of vascular research to $750 from $40,000. The tool uses affordable manufacturing processes and customizable components, making it easier for researchers to study vascular function.

SourceUniversity of Pittsburgh·JournalDevice·TypeExperimental study·DateFeb 2, 2026

Pitt and UPMC study finds epigenetic signature of pediatric traumatic brain injury, paves way for precision recovery tools

Researchers at Pitt and UPMC Children's Hospital discovered a biomarker of complicated pediatric traumatic brain injury, which may serve as dynamic indicators of post-injury recovery. The study found that children with TBI had a different epigenetic profile compared to those with orthopaedic injuries.

SourceUniversity of Pittsburgh·JournalJournal of Neurotrauma·DateDec 9, 2025

From light to logic

McMaster and Pittsburgh researchers have developed a soft material that can perform a NAND logic operation using only three beams of visible light. The breakthrough paves the way for autonomous systems with computation capabilities without traditional electronics.

SourceUniversity of Pittsburgh·JournalNature Communications·TypeObservational study·DateNov 20, 2025

Pitt researchers reveal hidden impacts of drinking-water treatment on urban streams

Pitt researchers found that orthophosphate additions in drinking water treatment can leak into urban streams, increasing phosphorus concentrations by over 600% and trace metals like copper and iron by nearly 3,500%. The study suggests urgent corrective actions to address phosphate leakage from buried infrastructure systems.

SourceUniversity of Pittsburgh·JournalPLOS Water·TypeData/statistical analysis·DateNov 13, 2025

Hitting a nerve

Engineers at the University of Pittsburgh have created a soft material with a nerve net that mimics how simple living systems coordinate motion. The material responds to chemical reactions, producing mechanical movement without electronics or motors.

SourceUniversity of Pittsburgh·JournalPNAS Nexus·TypeComputational simulation/modeling·DateOct 20, 2025

Retinal implant restores central vision in patients with advanced AMD, study co-led by Pitt investigator shows

A wireless retinal implant has been shown to restore central vision in patients with advanced age-related macular degeneration (AMD), with 81% of participants achieving clinically meaningful improvements in visual acuity. The device converted light into electrical signals, stimulating remaining retinal cells and restoring visual inform...

SourceUniversity of Pittsburgh·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial·DateOct 20, 2025

When the wireless data runs dry

Researchers developed a novel framework to qualitatively evaluate the quality of synthetic wireless data, improving AI model training with 4.3% performance gain. The framework assesses affinity and diversity in wireless signals, essential qualities for effective training.

SourceUniversity of Pittsburgh·TypeComputational simulation/modeling·DateSep 15, 2025

New Pitt research suggests cellphone data could help clinicians identify and treat mental health disorders

Researchers found that cellphone sensor data can be linked to a wider array of mental disorder symptoms, including those not specific to any one condition. The study used statistical analysis to correlate sensor data with symptom dimensions, revealing correlations with both specific behaviors and a general p-factor marker.

SourceUniversity of Pittsburgh·JournalJAMA Network Open·TypeData/statistical analysis·DateAug 5, 2025

The challenge to define true surface topography

Researchers from the University of Pittsburgh, University of Freiburg, and Saarland University launched a global challenge to measure and describe surface topography. The results showed that current industry-standard methods are limited and that more precise measurements are needed to accurately predict surface behavior.

SourceUniversity of Pittsburgh·JournalTribology Letters·TypeData/statistical analysis·DateJul 26, 2025

Pavlov’s dogs were conditioned to go to their treat. Why do some animals learn to interact with the bell instead?

Researchers discovered that sign trackers, which prioritize interacting with cues over waiting for rewards, rely on dopamine in specific brain regions. The study found that inhibiting dopamine prevented rats from learning to sign track, while increasing dopamine did not speed up the process.

SourceUniversity of Pittsburgh·JournalNeuroscience·TypeExperimental study·DateJul 15, 2025

Genetic ancestry linked to risk of severe dengue

Researchers found that individuals with European ancestry have a higher inflammatory response to the dengue virus, which can lead to severe disease. In contrast, those with African ancestry have a lower inflammatory response, making them less susceptible to severe dengue fever. The study's findings could lead to precision medicine appr...

SourceUniversity of Pittsburgh·JournalProceedings of the National Academy of Sciences·DateJun 30, 2025

A Pitt study has identified a protein that can separate critical metals from electronic waste

A University of Pittsburgh study has identified a protein called ferritin that can selectively recover critical metals like cobalt and nickel from liquid solutions. The process uses benign conditions and could significantly reduce energy demands and costs associated with metal recovery.

SourceUniversity of Pittsburgh·JournalEnvironmental Science & Technology Letters·TypeExperimental study·DateJun 26, 2025