Articles tagged with Respiratory Disorders
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A new study found that exercise-based rehabilitation programs can improve immune cell function in individuals with post-COVID syndrome. This leads to reduced inflammation and symptoms such as fatigue and joint pain. The research suggests that exercise may help restore a more normal, well-regulated immune system.
A new study found that children who prefer pickled, smoked, and fried foods are more likely to have asthma. In contrast, seafood preference appears to reduce asthma risk among normal-weight children. The findings highlight the importance of early-life dietary habits in shaping respiratory health.
A global study found that children under 14 years old lose nearly 8.45 million years of healthy life due to second-hand smoke exposure. The study, presented at the European Respiratory Society Congress, highlights the disproportionate burden on low-socio-economic regions.
Research presented at the European Respiratory Society Congress found a link between indoor wood burning and decline in lung function. The study used data from the English Longitudinal Study of Aging and found that people using solid fuel stoves had lower FEV₁ values, indicating increased risk of respiratory complications.
A pilot study found that hypnosis significantly improved patients' tolerance of masks, allowing them to breathe more comfortably. The study showed a substantial improvement in non-invasive ventilation (NIV) tolerance, reduced agitation, and lower requirements for sedation and anti-anxiety medication.
A gold-standard randomised-controlled trial found that specialised singing programmes can improve the symptoms and quality of life of people with lung disease, particularly those with chronic breathlessness. The SINFONIA study showed a significant improvement in quality of life for patients with COPD and ILD.
A multi-national study found that higher levels of air pollution are linked to worse symptoms of obstructive sleep apnea (OSA) in European patients. The study revealed a modest but measurable increase in the apnoea hypopnea index (AHI) for every one unit increase in PM10 concentration.
Research shows that remote monitoring of children's asthma can prevent hospitalizations by around 57%. The system helps keep symptoms under control, leading to better outcomes and lasting self-management skills. This innovative approach could revolutionize healthcare services for patients with asthma.
A low-cost drug, heparin, has been shown to be effective in treating seriously ill COVID-19 patients by reducing the risk of ventilation and death. The study found that inhaling heparin targeted directly to the lungs improved breathing and oxygen levels in patients.
Research presented at the European Respiratory Society Congress found that a healthy diet rich in fruits and vegetables can partially mitigate the adverse effects of air pollution on lung function. Women who consumed four portions of fruit per day or more appeared to have smaller reductions in lung function associated with air pollution.
Researchers found that universal screening for asthma symptoms and environmental triggers can identify more patients with asthma in specific communities. The study also highlights the importance of addressing environmental triggers in homes, particularly among children with asthma.
A new robot-assisted bronchoscope has been shown to diagnose tiny lung tumors in hard-to-reach areas with over 84% success rate, more than three times higher than traditional methods. The technology enables accurate diagnosis in patients where conventional bronchoscopy offers no viable option.
Research suggests that exposure to dog allergens in the home may reduce the risk of developing childhood asthma by five years old. Babies with higher levels of Can f1, a dog skin protein, had around a 48% lower risk of developing asthma and better lung function.
A new study found that inhaling marijuana daily is associated with a 44% increased chance of developing asthma. Experts say people should avoid inhaling cannabis to reduce the risk of chronic lung disease. The study's authors emphasize the need for clearer messages about the risks of cannabis use.
Researchers from UMD found that cats can survive bird flu if treated promptly with oseltamivir, a common influenza treatment. Early intervention significantly increases the chances of survival and strong protection against reinfection for several months.
Researchers at Tulane University have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, detecting TB in samples with very low levels of bacteria. The new test shows high sensitivity and accuracy, offering a significant step forward toward effective diagnoses via a variety of samples.
The American College of Chest Physicians has achieved a critical milestone in its advocacy efforts, leading to changes in federal coverage guidelines for noninvasive ventilation devices used in the home. These revised guidelines reflect major recommendations submitted by CHEST and aim to enhance patient care.
Researchers used AI to identify shared biological features between aging and fibrosis, finding new potential targets for therapy. The study found that IPF is not simply accelerated aging, but a unique biological condition shaped by age-related dysfunction.
Researchers at King's College London have discovered that cells use electricity to selectively target and eliminate the weakest neighbours, helping to maintain a balanced and healthy protective layer. This process, known as extrusion, is crucial for balancing cell division and death, and disrupting it can lead to disease.
Emphysema detected on low-dose chest CT scans in asymptomatic adults increases mortality risk over a 25-year follow-up period. The study found that emphysema severity is associated with higher COPD and cardiovascular disease mortality rates, suggesting it as a distinct disease entity linked to poorer health outcomes.
Penn Engineering researchers used a technique called photochemical cross-linking to stiffen lung tissue, revealing changes in cell behavior that may drive fibrosis. The team observed transitional cells caught in an identity crisis, unable to perform either role well, which contributed to disease progression.
Researchers at Institute of Science Tokyo found that basophils suppress lung inflammation during ARDS recovery, suggesting potential treatment strategies. Basophils release interleukin-4, which helps immune cells coordinate responses and alleviate lung inflammation.
Research published in Thorax found that a father's exposure to passive smoking as a child may impair the lifelong lung function of his children, putting them at risk of chronic obstructive pulmonary disease (COPD). The study included over 9,000 child participants and found that fathers' childhood passive smoke exposure was associated w...
A recent study found a sharp increase in hospitalisations for pertussis among children and adolescents in Tuscany, Italy, between 2016 and 2024. The study emphasizes the critical role of timely vaccination administration to prevent further cases and hospitalisations.
Researchers are using nanodiamonds and VEGF to design treatments for Congenital Diaphragmatic Hernia (CDH), a devastating disease affecting 1 in 3,000 newborns. The treatment aims to stimulate lung growth before birth and improve survival rates.
A new guideline from the Canadian Task Force on Preventive Health Care provides a menu of effective options to help people quit smoking, including behavioural and medication options. The guideline aims to address the challenges of nicotine addiction and offers personalized choices for quitting tobacco.
A study found that patients who communicate with their providers have better disease management, reducing exacerbations and hospital visits. The study suggests increasing conversations about disease education and self-management strategies can improve quality of life.
A recent study has consistently linked e-cigarette use to a higher risk of cigarette smoking and various health concerns in young people. The review found that vaping often precedes smoking and can lead to increased frequency and intensity of smoking, as well as associated risks such as asthma and depression.
A new study published in Aging-US found that frailty is associated with increased respiratory exacerbations and mortality in individuals with a history of cigarette smoking. Frail participants had a three- to five-fold higher chance of developing serious or frequent respiratory attacks, even if they had normal lung function.
A new study will investigate whether low levels of the lung protein CC16 in childhood can predict who will develop early chronic obstructive pulmonary disease (COPD) later in life. The five-year study aims to identify children at risk for early COPD and potentially intervene to prevent lung disease.
A comprehensive epidemiological study found that people who had COVID-19 are at increased risk of developing certain inflammatory diseases of the airways, such as asthma and chronic sinusitis. Vaccination against SARS-CoV-2 virus appears to reduce this risk.
The BREATHE-3 clinical trial evaluates a novel bronchoscopic device to open airways and release trapped air in patients with severe emphysema. The study will assess the safety and efficacy of the Apreo BREATHE Airway Scaffold, an implantable device granted FDA Breakthrough Device Designation.
A new study highlights how neighborhood conditions shape the seasonal surge of virus-triggered asthma emergencies among children. Children living in under-resourced communities face sharply higher rates of asthma flare-ups tied to viral infections during the first weeks of school.
A small randomized controlled trial found that blowing through a conch shell for six months reduced symptoms of obstructive sleep apnea, including daytime sleepiness and breathing interruptions. The study suggests that conch blowing may be a simple, low-cost alternative to traditional treatments like CPAP.
A new clinical research study found that young children lacked immunity to common respiratory viruses during the pandemic, leading to a post-pandemic resurgence. The study's findings enable more accurate predictions for future outbreaks and demonstrate the utility of longitudinal immunologic surveillance in children.
A multi-year clinical research study in US children documents the rebound of endemic respiratory viruses after the COVID-19 pandemic. The study shows that non-pharmaceutical interventions decreased circulation rates of common respiratory pathogens in children, enabling more accurate predictions for future outbreaks.
The project aims to develop novel, interpretable biomarkers using advanced artificial intelligence to overcome limitations in current diagnostic tools. The team will integrate multi-modal data and biomechanics for better diagnosis and tracking of chronic obstructive pulmonary disease (COPD).
Researchers at Osaka Metropolitan University found that elevated phosphate levels are associated with poor outcomes in canine respiratory disorders. The study used medical records from 133 dogs and identified heart rate, body temperature, and other factors as significant prognostic indicators.
Research finds CPAP lowers cardiovascular risk by 17% in patients with high-risk OSA, but may increase risk by 22% in those without high-risk OSA. The study suggests a more personalized approach to treating OSA, focusing on patients with high-risk features.
A new study sampled different lung regions in cystic fibrosis patients before and after treatment with modulators, revealing that infections persisted throughout the lungs and drove inflammation. The findings suggest damage may not be the main cause of infection persistence, raising concerns about ongoing lung function deterioration.
Researchers conducted a randomized clinical trial to compare low- and high-dose methylprednisolone with azithromycin for treating severe Mycoplasma pneumoniae pneumonia. The study found that lower dose regimen of glucocorticoids is sufficient, equally effective, and safer than the high dose regimen.
This article reviews bronchiectasis phenotypes and endotypes, exploring their impact on disease management and treatment strategies. Recent research has identified distinct inflammatory endotypes, guiding targeted therapies and improving patient outcomes through personalized approaches.
The American College of Chest Physicians has released a clinical guideline on the management of patients with early-stage non-small cell lung cancer. The guideline provides evidence-based recommendations for primary treatment and outlines three flowchart graphs outlining the recommended course of treatment based on patient risk. These ...
A new genetic study has identified genes involved in neuronal signalling and sensory pathways as key drivers of chronic cough. The findings advance our understanding of cough reflex hypersensitivity as a nervous system-mediated process, opening up opportunities for targeted treatments.
A new European study using geolocation technologies and satellite imagery found a clear link between urban conditions and increased asthma risk. The combined impact of urban environmental factors was shown to contribute to up to 11.6% of new cases, emphasizing the importance of health-focused environmental policies.
Research found that chronic exposure to PM10 and PM2.5 air pollutants activates harmful allergic-like immune responses in the lungs, leading to inflammation and scarring. The study suggests targeting oxidative stress or modulating NRF2 activity could be a new strategy to treat pollution-induced allergic inflammation.
A new study by NYU Langone Health researchers found that the shutdown of a significant fossil fuel pollution source near Pittsburgh, PA resulted in immediate improvements in respiratory health. Respiratory related emergency visits decreased by about 20% within weeks after the plant's closure.
Four abstracts using Bronchiectasis and NTM Research Registry data were presented at the World Bronchiectasis Conference, highlighting the importance of collaborative research and planning for multi-center clinical trials. The registry provides valuable clinical data from individuals with non-cystic fibrosis bronchiectasis and nontuber...
Research warns that GLP-1 drugs may not provide the long-term health benefit of improved heart and lung function. While they help with weight loss, patients may experience significant muscle loss, which can increase cardiovascular disease risk. Doctors are urging additional research to better understand the effects of these drugs.
A new study from Emory University reveals that maintaining optimal cardiovascular health can significantly improve overall physical and psychological well-being. The review confirms that heart-healthy behaviors positively impact brain function, vision, hearing, muscle strength, and reduce the risk of chronic diseases.
A study by University of California, Riverside researchers found that inhaling agricultural dust can alter the gut microbiome and impair intestinal function, leading to increased 'leaky gut' and associated chronic diseases. The study highlights the need for protective measures for agricultural workers.
A new study by Mass General Brigham investigators identified an ancient immune pathway that is activated in patients with acute chest syndrome (ACS) and serves as a key driver of the disease. Blocking this pathway with clinically approved drugs alleviated disease severity in preclinical models.
Researchers have discovered ancestral evolutionary links of Aspergillus latus strains through genome sequencing analyses, revealing potential for reduced susceptibility to antifungal medications. The study highlights the need for improved molecular diagnostic tools to accurately identify A. latus strains and manage aspergillosis.
Researchers have engineered a monoclonal antibody that blocks allergic reactions against common pollen when applied inside the nose of mice, providing new hope for hay fever sufferers. The treatment, known as a 'molecular shield,' acts immediately and locally at the lining of the nose to prevent IgE antibodies from being activated.
Clinical trials show sutezolid and delpazolid are safer alternatives to linezolid for treating drug-resistant TB, with no cases of nerve damage or blood toxicity reported. The findings suggest these drugs could replace linezolid in treatment regimens.
A special issue of Journal of Intensive Medicine provides key insights into selecting optimal non-invasive respiratory support strategies for AHRF, featuring review articles and original research. The collection offers guidance on the efficacy of HFNC, CPAP, NIV, and awake prone positioning to improve patient outcomes.
A study by Università Cattolica del Sacro Cuore found that individuals with negative asthma expectations report worse symptoms over time. Conversely, optimistic patients exhibit improved respiratory function and slower disease progression.
Researchers at the University of Surrey have identified genes that disrupt the survival of 'zombie' TB cells, which are resistant to antibiotics. By understanding these mechanisms, scientists can develop new drugs that target persisters and shorten treatment regimens.
Scientists successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology. The AT2-like cells were generated in just 7 to 10 days, a significant reduction compared to conventional methods.
Researchers at Stanford Medicine discovered that a common signaling pathway protects airways from damage caused by toxins like wildfire smoke or respiratory viruses. The drug, which activates the pathway, protected mice with influenza or COVID-19 infections, while blocking it caused severe damage to their airways.