Articles tagged with Disease Outbreaks
A team of researchers at the University of Waterloo and Dalhousie University have developed a method for forecasting short-term disease progression using limited data. The Sparsity and Delay Embedding-based Forecasting model, or SPADE4, uses machine learning to predict epidemic progressions with high accuracy.
A new AI-powered triage platform uses machine learning and metabolomics data to predict patient disease severity and length of hospitalization during a viral outbreak. The platform integrates routine clinical data, patient comorbidity information, and untargeted plasma metabolomics data to drive its predictions.
A new study found that voluntary collective isolation alone was ineffective in preventing the spread of COVID-19 among the Amazonian Tsimané. The researchers used a computer model and serological testing to confirm their predictions, showing nearly identical infection rates across communities.
A new study found that voluntary collective isolation was unlikely to prevent rapid spread of COVID-19 among the Tsimané, a small-scale Indigenous society in remote Amazonia. The simulation predicted nearly identical rates of infection in real-world data, highlighting the need for targeted interventions and medical resources
Researchers developed a deep-learning model to assess CXR images for probable COVID-19 severity. The model achieved an area under the receiver operating characteristic curve of 0.78 when predicting intensive care need within 24 hours.
A recent study published in Cell Host and Microbe reveals how flaviviruses hijack human cells to promote replication. The discovery of KAT5γ's critical role in viral replication paves the way for designing inhibitory molecules to stop viral replication.
The first locally acquired malaria cases in the US in 20 years have been reported, highlighting the need for clinicians to be vigilant about the disease's symptoms. Malaria thrives in warmer climates and can cause serious illness and death if not treated, emphasizing the importance of rapid diagnosis and treatment.
A study found that climate influences the spread of polycystic echinococcosis, a neglected disease with high mortality rates, in the Amazon region. Climate factors can predict potential infection hotspots.
Biologists argue that building on genomic sequencing momentum is critical in society's response to future pandemics. The technology improved during the COVID-19 pandemic, but gaps remain in global infrastructure and data sharing.
A new study suggests that ancient pathogens trapped in melting permafrost could cause significant ecological damage, with up to 3% of invasive pathogens becoming dominant. The researchers found that these 'time-traveling' pathogens could lead to unpredictable results, including up to one-third of host species dying out.
A study found that targeting the bottom 12.3% of wall surfaces can kill over 85% of Aedes aegypti mosquitoes, a vector for serious diseases like dengue and Zika. This approach could make indoor residual spraying cheaper and easier for individual householders to undertake.
CEPI and HMRI collaborate to leverage AI technology for faster vaccine development. The partnership aims to identify epitopes that stimulate the immune system, enabling swift clinical testing.
A new study suggests that wastewater monitoring can be an effective way to track the spread of infectious diseases. The research found that testing for COVID-19 in wastewater was an objective way to measure where the disease was spreading, with most samples processed in under four days.
A new study reveals that mobile phone data can be skewed towards more accessible populations, leading to misleading predictions and ineffective outbreak responses. Researchers urge acknowledging and measuring bias in all types of data to ensure accurate public health decisions.
A UCLA-led team is tracking mpox outbreaks across the US with a new surveillance project called CRASHED. The research aims to identify cases beyond high-risk groups and determine if mpox remains rare or resurges more broadly.
A new study found consistently high TB case rates among incarcerated people, but low detection rates. Nearly half of TB cases were not detected, highlighting the need for increased efforts to reduce TB spread in prisons.
A new study models the spread of African swine fever in US swine farms, finding that control actions can reduce secondary infections by up to 79% but an outbreak could still be persistent and costly. The model suggests that between-farm movements are the primary route of transmission.
Researchers at the University of Queensland have uncovered the atomic structure of the Langya virus, a highly infectious virus with pandemic potential. The study aims to develop broad-spectrum human vaccines and treatments for Henipaviruses, which cause severe disease and have the potential to get out of control.
Researchers at Trudeau Institute and Texas Biomedical Research Institute found that prior dengue infection can worsen Zika virus outcomes during pregnancy. Pregnant marmoset monkeys infected with dengue passed significantly more Zika virus to their fetuses than those without dengue, suggesting a link between the two viruses.
Experts highlight nine public health workforce strengths, 22 weaknesses, 14 opportunities and 14 threats in the nation's information systems. The report calls for a technology-enabled information infrastructure to deliver day-to-day essential services and respond effectively to emergencies.
Researchers discovered three 4,000-year-old cases of Yersinia pestis in human remains from mass burials in Somerset and Cumbria. The findings indicate the plague may have been easily transmitted across Britain, contradicting previous assumptions that it was brought by fleas.
A new identification tool called IDphy has been developed to accurately identify Phytophthora species, which cause significant economic and environmental losses. The tool uses data from ex-type cultures and includes features such as an interactive key, factsheets, and a mobile app.
A breakthrough surveillance tool has been developed to detect elevated risks of Buruli ulcer outbreaks in Victoria, utilizing possum 'poo' analysis. The tool reveals significant spatial correlation between clusters of Mycobacterium ulcerans positive possum excreta and human Buruli ulcer cases.
A new study by University of Wyoming researchers found that regular diagnostic testing and self-isolation can deliver higher net benefits than physical distancing strategies in combating infectious diseases. The study took into account the concept of superspreading, which made the testing-isolation approach even more effective.
The European Centre for Disease Prevention and Control highlights the rapid spread of avian influenza viruses worldwide, affecting wild bird populations and mammals. The authors warn that human infections with A(H5N1) can be severe and increase the risk of reassortment with mammalian viruses.
A study by Carnegie Mellon University found that customers who wore masks spent 25% less time shopping during the pandemic. Non-compliant customers did not change their shopping duration, despite being five times more likely to wear protective N95 masks.
A cohort study of 196 people treated with tecovirimat found that HIV status did not impact treatment outcomes. Only 22% of participants experienced nonsevere adverse effects, and 4 serious adverse events occurred, with 3 being persons with HIV. The findings contradict previous uncertainty about HIV's role in mpox acquisition.
The International Vaccine Institute (IVI) has started clinical development of DuoChol, a new oral cholera vaccine in capsule form. This innovation offers improved thermostability, reducing storage challenges, while making vaccines more accessible to those who need them most.
Scientists have found a rare yeast pathogen, Lodderomyces elongisporus, causing neonatal outbreaks in India despite strong disinfectant bleach. The fungus is rapidly evolving and has been linked to hospital equipment and apples treated with fungicides.
Researchers at MIT have created a vaccine printer that can produce hundreds of vaccine doses in a day, using microneedle patches that can be stored long-term at room temperature. The printer can be deployed anywhere vaccines are needed, providing on-demand vaccine production.
A workshop at the Santa Fe Institute explores the complex interplay of contagions, including infectious diseases, social phenomena, and online behavior. Researchers aim to develop new tools to study interactions between different types of contagion.
A highly pathogenic bird flu, H5N1, is spreading rapidly in the US, decimating wild birds and impacting poultry, with egg prices soaring. The study's findings highlight the need for unprecedented coordination to manage the spread of the disease, which may become endemic, posing risks to food security and the economy.
Researchers studied H7N9 epidemic waves in China from 2013 to 2017, analyzing gene sequences to build phylogenetic trees. They found the virus likely circulated in poultry for months before being detected, and suggest continuous monitoring of animal health is crucial
Researchers suggest that 'network immunity', generated by core members of the sexual network, halted the mpox epidemic. The theory proposes that as core members were infected first, they developed infection-induced immunity which slowed transmission.
A multidisciplinary research team has developed a promising virus-fighting protein using a quick, portable process that could be easily deployed at the source of a future virus outbreak. The protein, Griffithsin, disables a wide range of viruses, including COVID-19, and can be manufactured without living cells.
A growing number of European countries have experienced diphtheria outbreaks primarily associated with recently arrived migrants. Key findings indicate that whole genome sequencing and phylogenetic analysis reveal that the toxin-producing bacteria were acquired during migration rather than in their home country or Germany.
A study found that mutant strains of Salmonella cause more severe infections in commercial poultry than wild-type bacteria. The deletion of genes ttrA and pduA led to increased immune response and pathogenicity, emphasizing the importance of animal health measures and proper food conservation.
A national survey found that South Carolina residents were more hesitant to receive COVID-19 vaccines due to low confidence in public health scientists and collective responsibility. Researchers hope that targeted education efforts will address these factors and reduce vaccine hesitancy.
Researchers in Southern Nevada have detected Candida auris genetic material in untreated sewage samples from seven wastewater treatment facilities. The fungus was also found in nearly 80% of untreated sewage samples, indicating its spread in the region. Wastewater surveillance may provide an early warning system for public health actio...
The CABI Distribution Database contributed to a synoptic review of plant disease epidemics and outbreaks in 2021, identifying 15 new pathogens reported in Asia, Europe, the USA, and other parts of the Americas. The study highlights the time lag between first reports of a pathogen being made and major disease outbreaks being observed.
Researchers have developed an online tool, the 'Tree-Based Alignment Selector (T-BAS) toolkit', to identify and monitor plant pathogens, including Phytophthora species responsible for devastating plant diseases. The tool provides a living 'tree of life' with genetic sequence data, evolutionary history, and relationships within groups.
A recent study found that ocean warming triggers dinoRNAV infections in coral colonies, intensified in unhealthy colonies. This is the first empirical evidence of reef-wide dynamics of viruses infecting coral symbionts during heat waves.
A large typhoid outbreak on a Dutch ship was traced to contaminated drinking water, with 72 cases confirmed. The investigation found that sewage containing Salmonella typhi leaked into freshwater tanks, highlighting the importance of regular water quality inspections.
Researchers analysed wastewater from 10 cities to detect chemical and biological markers of health, including pesticides, pharmaceuticals and disease-causing viruses. The study found that analysing wastewater on a large scale could spot new outbreaks of diseases in communities early on.
Researchers at Goethe University Frankfurt have identified nitroxoline as a potential treatment alternative for mpox. The antibiotic demonstrates effectiveness against both the current mpox virus and a tecovirimat-resistant strain, offering a promising solution to combat the outbreak.
A new study found that frequent COVID surveillance testing protected nursing home residents by detecting infected staff earlier, disrupting transmission chains. The research showed that high testing frequency facilities had clinically meaningful reductions in resident cases and deaths, particularly before vaccine availability.
A new study by Emory University researchers found that asymptomatic individuals account for a significant proportion (74%) of dengue infections in an Amazonian city. The 'super spreader' spaces, where infected people frequent, are crucial in predicting and controlling outbreaks.
A new study from Osaka University found that COVID-19 TV coverage significantly increased hand hygiene compliance from 5% to over 70% in a matter of months. The researchers tracked the correlation between TV coverage and hand hygiene, finding a strong statistical connection between added airtime and increased compliance.
A recent analysis found that TikTok health information videos on Mpox are often inaccurate, incomplete, and of poor quality. This poses significant risks to public health, particularly during outbreaks.
Researchers suggest a four-part framework to identify animal viruses that may infect humans, focusing on viruses from repeat offender families and those with known human compatibility. By studying these viruses early, scientists can develop diagnostic tools and treatments, and be better prepared to combat future pandemics.
A study found that a commercial water purifier may have caused Mycobacterium abscessus infections in 4 cardiac surgery patients due to chlorine depletion. The hospital's water system was contaminated via municipal water, emphasizing the importance of monitoring and preventing mycobacteria.
The U.S. laboratory system needs improvement to ensure timely and accurate diagnosis, tracking, and response to infectious diseases like COVID-19 and Mpox. The authors suggest government and private institutions collaborate to implement systemic changes, including federal funding and public-private partnerships.
Public health officials and community leaders must team up to disseminate accurate vaccine narratives, as anti-vaccine activism poses a significant threat to global health. The Lancet-led viewpoint piece emphasizes the importance of effective communication strategies to counter misinformation and promote vaccine uptake.
A new study by Rice University and Houston Health Department shows that wastewater-based monitoring is an effective way to detect viral outbreaks in schools. The system allows for early detection of illnesses such as influenza, COVID-19, and RSV, enabling strategies to stop the onset of potential outbreaks.
A longitudinal study reveals Yersinia pestis, the bacteria that causes plague, was reintroduced into the Danish population from other parts of Europe again and again, with devastating effects. The analysis, reported today in Current Biology, identified plague for the first time from medieval Denmark.
Researchers identified genetic variants associated with susceptibility to Epizootic Hemorrhagic Disease (EHD) in white-tailed deer. The study found that deer with specific mutations are less susceptible to the disease, which has been on the rise in northern Illinois and neighboring states.
A new Stanford-led study uses satellite and land use data to predict malaria outbreaks in Madagascar, providing insights into the disease's distribution and burden. The research identifies rural areas with flooded rice fields as high-risk zones for malaria transmission.
A study has identified a severe form of mpox with a 15% mortality rate in people with advanced HIV disease and immunosuppression. The researchers recommend adding this form of mpox to the list of AIDS-defining conditions to guide management of immunocompromised individuals.
The US is not prepared to combat the spread of animal-borne diseases due to gaps among governmental agencies. A 'One Health' approach is needed to govern human-animal interactions effectively.
Scientists have developed a mouse model of mpox virus, revealing differences in virulence among genetic groups. The new model shows that the current outbreak strain, clade IIb, has a significantly lower mortality rate than previous strains.