Articles tagged with Placebo Effect
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A new meta-analysis of over 6,500 patients found that antidepressants work better than placebos across various mental disorders, with the difference varying by disorder type. The study also highlights the strong placebo effect in depression and its potential for new treatment concepts.
A new study by researchers at the University of Gothenburg supports the notion that Selective Serotonin Reuptake Inhibitors (SSRIs) exert a specific antidepressant effect. Contrary to the 'placebo effect' theory, SSRIs are shown to be effective in treating depression, even in patients without side effects.
A study found that the brain's reward center is tricked into thinking expensive wine tastes better due to its higher price. The 'marketing placebo effect' plays a role in this phenomenon, where identical products are perceived differently based on their prices.
A study by Stanford scholars found that people who believe they are less active than peers die younger, even if their actual activity levels are similar. This suggests that mindsets play a crucial role in health outcomes.
A recent study by University of Freiburg researchers found that an individual's expectations and self-perception play a significant role in determining the level of strenuousness experienced during physical exercise. The study, which involved 78 test subjects, showed that those who believed they were more athletic or had faith in sport...
A study by INSEAD found that labeling energy drinks as part of an alcohol cocktail increases perceived intoxication, leading to greater risk-taking, sexual confidence, and decreased intentions to drive. The effects were stronger for those who believed energy drinks boost the effect of liquor.
A study found that labeling cocktails with energy drinks increases perceived intoxication, risk-taking, and sexual self-confidence. Adding energy drinks to alcohol reduces the intention to drive under the influence.
A recent CU Boulder study found that the placebo effect can significantly reduce emotional pain and brain activity associated with social rejection. The study used fMRI to track brain responses in volunteers who had recently experienced a breakup, finding that placebos reduced physical pain and emotional distress.
A meta-analysis by psychologists at the University of Basel found that patients' confidence in medical personnel has a positive effect on satisfaction, health-related behavior, and quality of life. However, the study did not find a clear-cut result when using objective clinical parameters or doctors' assessments.
A new study found that patients given psychological support before heart surgery scored lower on disability tests, had better mental quality-of-life, and reported more physical activity. Personalized support appeared to have the greatest benefit, and a short-term intervention can be easily implemented in cardiac surgery units.
A small study found that augmented reality and serious gaming therapy significantly reduced phantom limb pain, improving quality of life. The therapy involved training a virtual arm, racing, and copying movements, leading to halved pain intensity and frequency.
A study found that patients who knowingly took a placebo pill alongside traditional treatment for lower back pain saw more improvement than those given treatment alone. The placebo effect was triggered by the patient-clinician relationship and ritual of taking pills, rather than conscious expectation of an active medicine.
A new study found that vasopressin increases placebo analgesic effects in women, particularly those with lower acute stress and anxiety. The findings suggest a new mechanism for the neurobiology of placebo effects and open up research directions for understanding the vasopressin system.
A study by Frank Germann and colleagues found that strong performance brands can improve performance in tasks such as golf putting and math tests. Participants who believed they were using a high-performance brand performed better than those who did not know the brand, even when using the same product. The effect is strongest among nov...
A large-scale study by the University of Melbourne found that both real and sham acupuncture showed a 40% improvement in hot flush severity and frequency after eight weeks. The benefits were sustained at six months. Women with breast cancer or ovarian removal were not included.
The National Association of Science Writers announced the winners of its 2015 Science in Society Journalism Awards, recognizing outstanding reporting on science and society. Winners include Judy Foreman for her book A Nation in Pain: Healing Our Biggest Health Problem, and Erik Vance for his article Why Nothing Works.
A systematic evidence review published in Annals of Internal Medicine finds that the way a placebo is delivered affects how patients respond to therapy. The study suggests that some placebos have stronger effects than others, potentially impacting the effectiveness of medical treatments.
Researchers found that subjects who knew they were receiving a fake pain treatment still experienced pain relief after multiple sessions. The study suggests that conditioning can create independent placebo effects that require both belief and consistent experiences. This could lead to new treatments for drug addiction or pain management.
Research shows preconceived beliefs create a strong placebo effect, changing brain chemistry and altering taste experience. Marketing actions can harness this effect to influence purchasing decisions.
The study of genomics effects on placebos introduces the concept of 'the placebome,' identifying a network of genes that significantly influence medicine and clinical trial design. Genetic variations in neurotransmitter pathways modify placebo effects, suggesting placebos play a larger role in healthcare than previously recognized.
Researchers explore whether genetic variations can modify the placebo effect, potentially leading to better patient selection for clinical trials. Genetic tests could help identify individuals who are unlikely to benefit from treatment, allowing for more efficient and effective medical care.
Researchers found that beliefs about nicotine can modulate brain activity and influence behavior, potentially leading to new addiction treatments. The study suggests that belief systems can induce physiological changes, allowing for the reverse-engineering of addiction.
A study published in JAMA Pediatrics found that agave nectar and placebo were perceived to be more effective than doing nothing in treating nighttime cough and sleep disturbance in infants and toddlers. Researchers compared treatment with agave nectar, placebo or no treatment at all on symptoms.
A study by Beth Israel Deaconess Medical Center found that patients' expectations, whether positive, negative, or neutral, significantly influence the effects of both medications and placebos on migraine pain. The researchers discovered that a positive message and powerful medication are essential for effective clinical care.
A meta-analysis of 16 randomized controlled trials found that Transcendental Meditation (TM) practice reduced trait anxiety in people with high anxiety levels. Studies showed significant reductions in anxiety, especially in those with elevated anxiety levels.
A recent study by the University of York found that copper bracelets and magnetic wrist straps offer no meaningful benefits for patients with active rheumatoid arthritis symptoms. Participants who wore these devices reported no significant improvements in pain, swelling, or disease progression compared to a placebo.
University of Arizona researchers have discovered that ultrasound waves applied to specific areas of the brain can alter patients' moods. The study, led by Dr. Stuart Hameroff, found improvements in mood for up to 40 minutes following treatment with brain ultrasound, compared to no difference when the machine was switched off.
Psychological interventions often don't account for the placebo effect, which can lead to false claims of treatment effectiveness. Researchers found that even with active control groups, expectations for improvement can still be influenced by prior experiences with the training tasks.
A UK survey found that 97% of doctors have prescribed placebo treatments to patients at least once, with impure placebos being used more frequently. Doctors cited treating psychological effects and reassuring patients as reasons for prescribing placebos, while also acknowledging the need for patient trust.
A new study has identified a genetic marker for the placebo response in Irritable Bowel Syndrome (IBS) patients, which could influence patient care and clinical trial design. The findings suggest that individuals with a specific genotype have a higher response to placebos when treated by a warm, supportive healthcare provider.
Researchers identified a novel mechanism that explains the power of placebos and nocebos, demonstrating the unconscious mind plays a key role in pain experiences. Studies showed that patients can show clinical improvement even when receiving treatments devoid of active ingredients or known therapeutic efficacy.
Research highlights the need for better representation of placebo effects in clinical trial participant information leaflets. The study found that placebos were often described negatively and ignored potential benefits.
Research highlights suggestion's wide-ranging impact on human memory, learning, and behavior. The 'response expectancies' phenomenon explains how anticipating outcomes influences thoughts and actions.
A recent article in the Hastings Center Report raises questions about the AMA's policy on prescribing placebos, arguing that it may not be the best way to protect or benefit patients. The article suggests that some bioethicists argue that an undisclosed placebo is sometimes the best available treatment for certain patients.
A study by neuroscientists at the University at Buffalo proposes that ingesting placenta components may provide benefits to human mothers and potentially to non-human mammals. The research highlights the importance of further studying placentophagia, a practice observed in many non-human mammalian species.
Two randomized controlled trials found acupuncture to be equally effective as sham acupuncture in treating migraines. About half of patients showed improvement after 16 weeks. The clinical effect of acupuncture is considered minor and may be due to the placebo effect.
A study found that marijuana ingredients Δ9-THC and CBD affect different regions of the brain during visual processing tasks. Δ9-THC increased psychotic symptoms by modulating prefrontal and striatal function, while CBD enhanced response to salient stimuli.
A large-scale study found that saw palmetto extract did not improve lower urinary tract symptoms in men with prostate enlargement. The researchers tested up to three times the standard dose and discovered no measurable benefits or toxicity.
A study examining placebo treatments in asthma patients found that they were equally effective as albuterol inhalers in relieving patient-reported symptoms. However, there was no objective impact on lung function, highlighting the subjective nature of the placebo effect.
Researchers analyzed 119 clinical trials to determine the magnitude of placebo effect and no treatment effect on headache recovery rate. The study found a high overall recovery rate of 36% in 'no treatment' control groups.
Researchers have found that placebos work even when administered honestly, leading to improved symptoms for patients with irritable bowel syndrome. The study suggests that the performance of medical ritual may hold significant benefits, independent of patient knowledge.
A survey of over-the-counter medication users found that red and pink tablets are preferred due to their aesthetic appeal. The study suggests that the color of a pill can boost compliance and improve outcomes, and recommends considering aesthetics in pharmaceutical formulation.
A recent study found that transforaminal steroid injection is a viable alternative to surgery for lumbar radicular pain due to disc herniation, with 54% of patients achieving pain relief after 1 month. The treatment was shown to be more effective than other methods, including local anesthesia and saline injections.
Recent research highlights the existence of multiple placebo effects, influenced by psychological and neurobiological factors. Placebo effects can be robust in both laboratory and clinical settings, and can even enhance the efficacy of treatments.
Researchers successfully treated psoriasis patients with a reduced dose of steroid medication using the placebo effect, improving treatment for chronic diseases. The new technique could maximize drug benefits, reduce side effects and increase patient adherence.
The PROTECT trial found that rolofylline had no significant effect on primary or secondary end-points in patients with acute heart failure, including dyspnea improvement and persistent renal impairment. The study did show an increased risk of neurological events in rolofylline-treated patients.
Studies found that botanicals were safe, but did not have a significant effect on reducing hot flashes or improving cognitive function compared to hormone therapy. The studies enrolled over 150 women and followed them for 12 months.
A new study by The Endocrine Society found that male recreational athletes who believed they were using growth hormone experienced improved athletic performance, even when given a placebo. In contrast, female athletes showed little benefit from the placebo effect.
A study found that acupuncture reduces hot flushes in breast cancer patients taking tamoxifen by 50%, with a sustained effect after treatment cessation. Acupuncture also improves overall well-being and has the advantage of being cheap and side-effect-free compared to other treatments.
A study by Ohio State University found no improvement in immune status, wound healing, or pain control among participants exposed to aromatherapy oils. However, lemon oil showed a positive effect on moods, while lavender oil had no impact.
Homoeopathy faces growing opposition in the UK, where it is criticized for its lack of scientific evidence and promotion of ineffective treatments. Despite this, the practice remains popular with the public, with an estimated £38 million market value in 2007.
A recent study published in The Lancet found that artificial food colorings and additives can increase levels of hyperactivity in children up to middle childhood. The effects were observed across a wide range of severities and in the general population, not just in those with extreme hyperactivity.
Scientists pinpointed the nucleus accumbens as key player in the placebo effect, which influences treatment efficacy through expectation. The study found that anticipation of pain relief triggers dopamine release from NAC.
Researchers found that housekeepers' perceived levels of exercise positively impacted their health, with significant weight loss and improved blood pressure. The study suggests the placebo effect plays a role in exercise's benefits.
A study of 270 individuals with chronic arm pain found that patients receiving sham acupuncture reported a more significant decrease in pain and symptom severity than those receiving placebo pills. The results suggest the medical ritual of a device can deliver an enhanced placebo effect beyond that of a placebo pill.
A study of people with fibromyalgia found those with greater hour-to-hour and day-to-day variability in their pain levels were more likely to respond to placebos. The researchers used electronic diaries to track participants' pain levels, which proved more accurate than previous methods.
A study of 110 homoeopathy trials and 110 conventional medicine trials found that smaller, lower-quality trials showed more beneficial treatment effects for homoeopathy. However, larger, higher-quality trials revealed no significant evidence that homoeopathy was superior to placebo.
A new study provides direct evidence that the brain's own pain-fighting chemicals play a role in the placebo effect, reducing feelings of pain. Participants who received a sham pain treatment reported increased activity in their mu opioid endorphin system after being told they were receiving a medicine.
A small group of stroke patients showed significant improvement in motor function after receiving repetitive transcranial magnetic stimulation. The treatment, which is non-invasive and painless, promotes increased activity in the damaged hemisphere by reducing motor activity in the unaffected hemisphere.
A 12-month quality of life study with Parkinson's patients shows significant improvement in movement and quality of life after receiving a transplant or sham surgery, regardless of actual treatment. The study suggests that the placebo effect plays a crucial role in this disease.