Articles tagged with Population Genetics
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
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Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A recent study has uncovered three previously unreported genetic loci associated with eyebrow thickness in Europeans, as well as rediscovering two of the four genetic loci previously found in non-Europeans. The research expands genetic knowledge on human eyebrow variation, with implications for dermatology and other fields.
Researchers found that individuals within two Xiongnu elite cemeteries exhibited extremely high genetic diversity, confirming the empire as a multiethnic entity. High status individuals showed lower genetic diversity, while those of lower status had higher heterogeneity, suggesting a diverse origin pool.
Genetic welding proposes using CRISPR-Cas9 technology to rapidly change evolutionary courses in animals or plants. Cutting argues that this method requires scientific and ethical scrutiny before its application.
Researchers analyzed ancient DNA from Cueva del Malalmuerzo in southern Spain, uncovering the oldest known human genome from this region. The study found a direct genetic link between the new genome and earlier populations in Belgium and beyond, shedding light on the Iberian Peninsula's role as an Ice Age refuge.
The study of 356 prehistoric hunter-gatherers from across Eurasia sheds light on the movements and genetic replacements of ancient populations. Genetic analysis reveals that populations in western Europe took shelter during the Last Glacial Maximum, while those in central and southern Europe died out or replaced with new gene pools.
Researchers found 21 Alzheimer's disease-related genes associated with obesity, including those linked to neuro-inflammation and amyloid-beta protein deposition. Obesity in midlife and women is more closely linked to dementia risk than late life or men.
A study by the University of Tsukuba found that Siebold's beech populations on Okushiri Island have high genetic diversity, suggesting they may have persisted there since before the last glacial maximum. This challenges the assumption that island populations are less genetically diverse due to geographical isolation.
Researchers analyzed 100 ancient genomes to understand kinship and marriage rules in Minoan Crete and Mycenaean Greece. They found that cousin marriages were common, with over 90% of sons marrying within their own family's hamlet.
A new twin study by Karolinska Institutet suggests that the same genes may be behind both cardiometabolic diseases and dementia. The study found that individuals with multiple cardiometabolic conditions had a significantly increased risk of developing dementia.
Researchers advocate for descendant community involvement in ancient DNA research to ensure benefits and risks are shared fairly. Without such guidance, the science can be exploitative, perpetuating colonial practices and harming modern Indigenous groups.
Researchers found that wooded areas, cropland, roads, and housing developments are obstacles to snake relocation. Reconnecting fragmented populations through strategic habitat changes could help restore the species to a thriving state.
A global registry for gene-drive modified organisms could facilitate transparent communication, monitor ecological impacts, and inform local decision-making. Experts agree that a registry is necessary for the fair development, testing, and use of gene-drive technologies.
Researchers at the University of Huddersfield used ancient DNA to reveal large-scale immigration in Early Bronze Age Orkney, contrary to popular belief. The findings also showed unusual female-dominated immigration during this period.
A team of scientists analyzed ancient DNA from medieval German Jews and found that the Ashkenazi Jewish community was more genetically diverse than modern-day Jews. The study suggests that the founder event occurred before the 14th century, with a small population giving rise to the modern Ashkenazi Jewish population.
A study found that South Asian women with genes associated with type 2 diabetes are at a higher risk of developing gestational diabetes during pregnancy. The researchers identified genetic signatures linked with type 2 diabetes risk as strongly and independently associated with gestational diabetes in this population.
Researchers analyzed DNA from 13 Neandertals, finding evidence of a close-knit community with 10-20 individuals. Genetic data suggests that female migration played a key role in maintaining the group's cohesion, contradicting previous theories about male-dominated movements.
A large Kaiser Permanente study found that most patients with a thoracic aortic aneurysm less than 5.5 cm are not at high risk of experiencing dissection or requiring surgery. The study's findings support the current consensus guidelines recommending surgery for patients with larger aneurysms.
A recent study found that cancer biomarker data is biased towards European populations, potentially misclassifying patients of Asian or African descent. The researchers propose a computational approach to correct this bias, which could have significant implications for treatment selection.
A study published in Science found that more than one-tenth of the world's terrestrial genetic diversity may already be lost due to climate change and habitat destruction. This could have serious implications for species' ability to adapt to climate change, highlighting the need for urgent conservation efforts.
A recent genetic study has found that three-quarters of the Early Medieval population in Eastern England was comprised of migrants originating from Continental regions bordering the North Sea. These migrants intermarried with local populations, but integration varied greatly from region to region.
A recent genetic study has shed new light on the Anglo-Saxon migration to Britain, revealing that around 75% of Eastern and Southern English populations descended from continental migrants. The integration of these migrant families with the existing British population varied by region and community.
Researchers found that nearly nine in ten cases of sudden cardiac death due to hypertrophic cardiomyopathy (HCM) are preceded by symptoms, ECG abnormalities, or a positive family history. Expanded screening programs could aid in the prevention of SCD in young individuals with HCM.
A new study from Lund University reveals that PCA, a widely used statistical method in population genetics, is deeply flawed. The method can produce flexible and unreliable results, leading to misconceptions about ethnicity and genetic relationships.
A new study from Lund University reveals that the most common analytical method in population genetics is deeply flawed, leading to incorrect results and misconceptions about ethnicity and genetic relationships. The method has been used in hundreds of thousands of studies, including medical genetics and commercial ancestry tests.
The University of Guam is conducting a four-person research team's study on the genetics of corals from the Northern Mariana Islands to understand coral population connections, diversity, and adaptations. The study aims to identify potential reserves for declining reefs and assess the impact of warming waters.
A study by OIST Graduate University's Marine Biophysics Unit found that mangroves in the Ryukyu Islands have limited connectivity, making it crucial to protect isolated forests. The research used genetics and oceanography to track propagule dispersal, revealing rare genetic exchanges between islands.
The Sixty-third Supplement to the Check-list of North American Birds updates bird classifications, including meadowlark species splits, hummingbird recognitions, kite separations, and the addition of a giant-petrel. New subspecies are also recognized for some bird species, reflecting advances in genetic analysis.
A large genomic study of snapper has identified three distinct oceanic snapper populations between Shark Bay and Ceduna in South Australia. The populations are genetically distinct and have unique geographical ranges, suggesting that snapper can make long-distance movements.
Researchers have discovered rare colonies of Rock Doves, the wild ancestors of common domestic and feral pigeons, on secluded Scottish and Irish islands. The findings provide valuable insights into how the domestic pigeon came to be, with varying degrees of interbreeding between the two forms of the species.
A previously unknown subpopulation of polar bears living in Southeast Greenland has been genetically distinct and uniquely adapted to its environment. The study provides insight into how the species might persist into the future, but highlights the need for careful extrapolation due to limited access to sea ice.
A study of ancient DNA from a 100,000-year-old polar bear genome found that extensive hybridization between polar bears and brown bears occurred during the last warm interglacial period. As a result, all living brown bears today have some polar bear ancestry.
A world-first study from the University of South Australia found a direct link between vitamin D deficiency and increased risk of dementia and stroke. The study analyzed data from 294,514 participants and found that up to 17% of dementia cases might have been avoided by boosting vitamin D levels.
A study found that around one in 500 men carry an extra sex chromosome, putting them at increased risk of several common diseases. Men with XXY or XYY chromosomes have higher risks of reproductive problems, type 2 diabetes, and other health conditions.
Researchers analyzed 16 ancient genomes from Wallacea, revealing striking differences between regions and a previously unknown ancestry contribution from Mainland Southeast Asia. The findings suggest multiple human dispersals into Wallacea and major implications for the understanding of Neolithic dispersals into Island Southeast Asia.
A massive global study of diverse populations has significantly advanced the understanding of type 2 diabetes by identifying 117 genes that contribute to the disease. The research used genetic data from almost 181,000 people with type 2 diabetes and 1.16 million without it.
Human activity on Hainan Island is causing changes in the body shapes and diets of tropical birds, resulting in biotic homogenisation. Despite efforts to protect biodiversity, the island's unique ecosystem is being affected by large-scale economic and land-use changes.
The trial evaluated the use of mavacamten as an alternative to heart surgery or alcohol septal ablation for treating hypertrophic cardiomyopathy. Findings showed significant reduction in left ventricular outflow tract pressure gradient and improvements in quality-of-life measures.
A multidisciplinary team analyzed ancient DNA from the Carpathian Basin to reveal clues about the Avars' origins. The research found that the Avar elites had ancestry from Northeast Asia and the North Caucasus, suggesting a rapid trans-Eurasian migration
Scientists at UC San Diego are working on next-generation gene drive systems based on CRISPR technology to combat malaria and reduce mosquito populations. The $1.4 million grant will support the development of new technologies, including a neutralizing system called ERACR, to mitigate risks associated with gene editing in mosquitoes.
Researchers are combining optogenetics and fMRI to study the links between brain activity and behavior. This hybrid approach allows for targeted manipulation and monitoring of brain function in awake and behaving rodents, providing valuable insights into neural mechanisms.
A new Brazilian database of whole-genome sequences brings diverse genetic information to international databases, shedding light on the genetics of aging and disease in Brazil's elderly population. The study identified over 2 million novel genetic variants, providing insights into the health and well-being of older adults.
Researchers from OIST found that Escherichia coli bacteria form lanes of genetically similar individuals when constrained to a channel, aligning parallel to the barriers. The study, published in PNAS, used microfluidic platforms and simulations to observe population dynamics over several generations.
A comprehensive genetic study found actionable pharmacogenomic variation affecting drugs in the Qatari population, highlighting diverse distribution of variants compared to other world populations. The study suggests potential implications for preemptive pharmacogenomic implementation in Qatar and beyond.
A genetic database has been created in El Salvador to help identify missing persons and victims of the country's civil war. The database, which includes 400 individuals, uses advanced sequencing technologies to assess genetic relationships between remains and relatives.
Researchers have identified genes associated with spinach's resistance to downy mildew and its levels of oxalates. The findings could help breeders produce disease-resistant varieties with more consumer appeal, improving spinach's market prospects.
A study by UC Riverside scientists has identified a set of genes on a single chromosome associated with the production of male or female offspring in ant colonies. The discovery sheds light on the complex relationships between genetics and environmental factors in shaping the sex ratio of these societies.
A new study from the University of South Australia found that vitamin D deficiency is associated with a higher risk of heart disease and higher blood pressure. Increasing vitamin D levels in deficient individuals may prevent up to 4.4% of all CVD cases, according to the research.
A new study tracked the spread of a genetic mutation that causes young-onset heart arrhythmia across continents over centuries. The research found that the mutation was passed down from Northern Europe to other parts of the world through migration, and identified a specific gene, KCNQ1, as the cause of the disease.
A high-resolution map of Arab and Middle Eastern population genetics has been unveiled, providing new insights into human history in the region. The study revealed that ancient populations in the Arabian Peninsula played a central role in early human migration out of Africa.
Researchers found that heritage-specific diets varied across Latinx groups, with Mexican and Puerto Rican diets being healthier. The study suggests that longer years living in the US may lead to less healthy dietary patterns among Cuban, Mexican, and Puerto Rican groups.
Researchers analyzed 1,785 ancient human genomes to determine parental relatedness, revealing that cousin marriages occurred only 3% of the time. The new method allowed for more efficient screening of ancient DNA, also providing insights into population dynamics and demographic impact of agriculture.
A new study using Neanderthal fragments suggests that generation intervals have fluctuated over the past 40,000 years, with human life history changing in response to environmental and cultural factors. The research found that Eurasian populations reproduced at a younger age than those in Europe, indicating a difference of 3-5 years in...
Researchers identified distinct epigenetic patterns associated with heart disease in diverse populations, offering potential early warning signs. The study analyzed genome data from four cohorts and found unique methylation points linked to coronary heart disease.
A new study identifies at least three migratory events that shaped central European prehistory, revealing a more dynamic period than previously thought. Genetic profiles show evidence of recent migrations and novel insights into social processes, such as the expansion of Corded Ware culture and the assimilation of women.
A 7,000-year-old human skeleton from Sulawesi has provided new insights into ancient human relations. The genome analysis shows a connection to the first modern humans to reach Oceania and a mix of Denisovan and Asian genetic components.
Researchers sequenced DNA from plant specimens collected nearly 50 years ago to analyze genetic diversity and its response to climate change. The study found that several species restricted to the Guadalupe Mountains had surprisingly high amounts of genetic diversity, which could help them adapt to changing conditions.
A single butterfly species introduced to an island in the 1990s had a significant impact on several insect populations, leading to genetic decline and high extinction risk for some species. The parasitoid wasp's mobility and symbiotic bacterial relationships played key roles in shaping this outcome.
Researchers identified a novel lncRNA, Teshl, which plays a crucial role in the development of Y-bearing sperm and regulates sex chromosome gene expression. The study provides new insights into sex ratio variations and suggests that genetics may be a key factor in human male infertility.
Researchers analyzed Neandertal and Denisovan genomes to identify blood groups, confirming their African origin and Eurasian dispersal. The study also found evidence of low genetic diversity and possible demographic fragility, shedding light on the disappearance of Neandertals.
A genetic analysis of brook trout in Loyalsock Creek drainage reveals that fish are moving between tributaries, using the mainstem as a seasonal corridor. This finding contradicts previous research and suggests that conservation efforts should focus on larger streams and rivers to protect critical movement corridors.