Articles tagged with Brain
A new study found that people with sleep apnea are more likely to engage in risky driving behaviors such as speeding and hard braking. The researchers monitored the driving habits of 96 older adults under real-world conditions and collected data on over 100,000 trips. They also assessed cognitive impairments and molecular signs of earl...
Researchers at University of Bonn identified a key enzyme, RIM1, that maintains synaptic homeostasis and prevents excessive brain activity. The discovery has implications for understanding diseases such as epilepsy, schizophrenia, and autism.
A study at the University of Helsinki found that in utero exposure to mother's antiepileptic or antidepressant medication can lead to widespread changes in cortical networks, affecting local and global brain function. This may have implications for infants' neuropsychological development and future research on environmental factors.
A study led by MUSC researchers found that inhibiting the complement system with CR2Crry can prevent long-term brain damage and improve outcomes in premature infants with germinal matrix hemorrhage. The treatment has shown improved survival, weight gain, reduced brain injury, and enhanced motor and cognitive performances.
A study by Tokyo University of Science researchers has demonstrated that a computationally-light model can simulate complex brain cell responses, including periodic and quasi-periodic responses. The Izhikevich neuron model was found to be capable of reproducing both types of responses at lower computational cost.
Researchers at Institut Pasteur have found that hypothalamic neurons can directly detect variations in bacterial activity, adapting appetite and body temperature accordingly. This discovery could lead to new treatments for diabetes and obesity.
Researchers found that neuronal ensembles in the amygdala and prefrontal cortex existed before memory acquisition, but developed through experience in the hippocampus. The study also revealed that ensemble synchrony across brain regions was particularly strong during transient bursts of activity, suggesting a role in memory consolidation.
A study from the University of Pittsburgh found that methionine restriction can slow down the growth of difficult-to-treat brain tumors in children, known as diffuse midline gliomas. The researchers discovered that these tumors are uniquely dependent on methionine, an amino acid, and that depleting it can repress cancer cell growth.
Researchers have identified a potential method of preventing damaging seizure activity by restoring the integrity of blood vessels in the brain. This breakthrough could hold promise for treating patients who are currently non-responsive to anti-seizure medications.
A study by Kyoto University researchers reveals that human fetuses develop slower shoulder growth before birth, alleviating complications during delivery. This adaptation allows for a safer passage through the birth canal, reconciling the incompatibility between wide shoulders and narrow pelvis.
Dr. Aaron Phillips received the 2021 Turnbull-Tator Award for his innovative research on neuroprosthetic baroreflex controls after spinal cord injury. He aims to develop a widely available therapy to improve blood pressure stability and quality of life for those affected.
Researchers found a higher number of small HDL particles in cerebrospinal fluid is associated with better cognitive performance and lower risk for Alzheimer's disease. These particles may play a key role in clearing amyloid beta peptides, which contribute to the disease.
A new robotic system allows surgeons to remotely treat patients experiencing a stroke or aneurysm, providing teleoperated endovascular treatment during the critical golden hour. With just one hour of training, neurosurgeons can successfully operate the system to guide a wire through complex vessels and reach difficult-to-reach areas.
A team of researchers from Kobe and Kyoto universities proposes an ethical framework for conducting research on conscious brain organoids. The framework assumes that brain organoids already possess consciousness and recommends guidelines similar to those for animal experiments. Key considerations include minimizing the number of organo...
A recent study of 280 mother-infant pairs found that prenatal exposure to social disadvantage and psychosocial stress was associated with reduced infant brain volumes at birth. The researchers used magnetic resonance imaging (MRI) to measure the brain volumes of the infants at birth.
A study of NASA, ESA, and Russian space agency data found that extended spaceflight leads to changes in the brain's perivascular spaces. The research, led by Medical University of South Carolina scientists, used MRI scans to evaluate brain changes before and after six months on the International Space Station.
Research found that bilingualism can slow down age-related changes in the human brain, with longer language proficiency linked to improved conflict resolution skills. Bilingual speakers showed better performance in a flanker task, indicating enhanced inhibitory executive control.
A new study by the University of Washington's Institute for Learning & Brain Sciences finds that children can develop key reading skills in a virtual classroom with other students. The 'Reading Camp' program demonstrates not only its effectiveness but also its potential to reach larger numbers of students remotely.
A kindness training program adapted from Children's Kindness Network improves both parents' resilience and children's empathy. The study found that teaching kindness at home boosts parental resilience and enhances emotional intelligence in preschoolers, supporting overall brain health.
A Norwegian University of Science and Technology-developed nasal spray has been tested on over 200 acute overdose patients, restoring breathing in 80% of cases within 10 minutes. The study's findings suggest the nasal spray provides enough antidote for patients to breathe on their own while minimizing the risk of triggering abstinence.
Researchers discovered that the brain formats working memory representations into a shared, line-like shape. This finding suggests that the brain selectively stores relevant information while discarding irrelevant content, and has implications for our understanding of psychiatric and neurologic symptoms such as schizophrenia.
A new study validates the Healthy Aging Brain Care Monitor as an accurate tool for monitoring post-intensive care unit (ICU) symptoms among ICU survivors through caregiver input. The tool assesses both patient and caregiver burden, providing clinically relevant information on physical, mental, and emotional symptoms.
A study found a shift in the profile of specialized lipid mediators from pro-resolving to pro-inflammatory in patients with cognitive impairment, correlating with severity of cognition impairment. The researchers identified novel mechanisms of brain health and potential therapeutic targets for slowing down Alzheimer's disease onset.
Researchers developed an audio-tactile sensory substitution device (SSD) that converts sound frequencies to vibrations, significantly improving speech comprehension in noisy environments. The technology has shown promise in training hearing-impaired individuals to better understand speech.
Researchers at Washington State University have demonstrated a way to make memristors using honey, which can mimic the work of human synapses and process data in memory. The honey memristor chips could lead to the development of neuromorphic computing systems that function like the human brain.
Researchers at Aarhus University review 20 years of music and brain research, revealing music's unique property of using expectations to influence behavior and emotions. The study explores how music activates the brain's reward system through dopamine release and explains music processing mechanisms.
A new study reveals that greater left-brain asymmetry is related to both better and average performance on reading ability tests, depending on the analysis method used. The findings support two opposing theories of language processing, suggesting a complex relationship between brain structure and speech sound processing.
Scientists at Johannes Gutenberg University discovered that fruit fly eyes can distinguish six types of global motion patterns generated by self-motion. The T4/T5 cell subtypes directly represent complex motion cues rather than uniform directions, matching the fly's actual behavior closely.
Electrical synapses play a vital role in brain function and stability, influencing individual nerve cell activity. In Drosophila, researchers found electrical synapses occur in almost all brain areas, affecting visual processing and neuron stability.
A study of patients treated with edoxaban and dual antiplatelet therapy (DAPT) after TAVR found that edoxaban reduced subclinical leaflet thrombosis, but did not affect stroke risk. Rates of death, stroke, and cognitive decline were similar in both groups.
Researchers have discovered a significant association between acute kidney injury and an increased risk of developing dementia in patients hospitalized with AKI. Early detection and monitoring may lead to improved outcomes for this high-risk population.
A clinical study from Lund University found that athletes with prolonged concussion symptoms have damaged nerves in the inner ear, particularly the vestibular nerve. This impairment leads to balance problems, dizziness, and difficulty focusing, affecting daily life.
A study published in Current Biology found that people share similar odour preferences regardless of cultural background. The researchers discovered that the structure of the odour molecule determines whether a smell is considered pleasant or not.
A study reveals that Alzheimer's patients experience lethargy due to the degeneration of neurons that keep them awake, not a lack of sleep. Researchers developed a hypothesis that these patients have trouble staying awake and are testing a treatment approach to shut down the system keeping them awake.
The completed human genome assembly has revealed new insights into human evolution and diseases. Researchers found that highly repetitive regions, including segmental duplications, contain genes critical for brain development and function. These findings shed light on the genetic factors that make humans distinct from other primates.
A recent report by the International Society of Microbiota confirms a bidirectional interplay between gut microbiota and various organs, highlighting the crucial role of microbiota in disease pathogenesis. The report also explores therapeutic strategies for manipulating gut microbiota to prevent and treat disorders.
A landmark study found that autistic individuals think as quickly and rationally as non-autistic people, challenging the idea that autism is a mental processing disorder. The research suggests that certain fundamental processes are more similar between autistic and non-autistic individuals than previously thought.
A study of over 365,000 adults found that people who survive an ischemic stroke are more likely to develop major heart complications and have an increased risk of death and future strokes. Researchers highlight the importance of secondary prevention efforts for this high-risk population.
Neural speech processing matures significantly in infancy, but certain abilities like sound discrimination still develop. A study found that children from birth to 2.5 years show varying levels of maturation in auditory skills essential for language learning.
A genetic disease in children, CHARGE syndrome causes intellectual disability, attention deficit disorder, and autism. The INRS team is studying the gene's impact on brain development to identify potential treatments.
Researchers developed a novel delirium severity score to assess its impact on patient outcomes. The DEL-S score is associated with longer hospital stays, increased costs, and mortality in older patients with delirium.
The Biophotonics Congress: Biomedical Optics will bring together biomedical experts to discuss advancements in clinical and translational biophotonics. Key findings include the development of label-free spectroscopy methods for identifying parathyroid glands during thyroidectomies.
A new study published in Drug and Alcohol Review found that binaural beats are being used as digital drugs by over 30,000 people worldwide, with users primarily seeking relaxation and mood change. The survey also revealed that binaural beat listeners are more likely to be younger and report recent use of prohibited drugs.
A new multimodal eye scanner combining optical coherence tomography (OCT) and Raman spectroscopy enables the detection of molecular information in the internal structure of the eye. This technology aims to detect neurodegenerative diseases, such as Alzheimer's and Parkinson's, at an early stage, improving treatment options.
A new study by researchers at the University of Chicago Medicine has identified a set of sporadic genetic mutations that make it more likely a person will develop cavernous angiomas, which can lead to stroke and seizures. Understanding these underlying causes is key to identifying patients at risk and finding effective treatments.
A new study shows that a potential treatment for Alzheimer's disease, sargramostim, improves cognitive function in people with Down syndrome and normal aging mice. The drug reverses learning and memory deficits, nerve cell loss, and brain abnormalities in mouse models of Down syndrome and aging.
A study led by Max Planck researchers found that parrots with large relative brain sizes have longer lifespans, averaging up to 30 years. This suggests that increased cognitive ability may help parrots navigate threats and enjoy longer lives.
A new study by University of Cincinnati researchers analyzed outcome data from a large cohort of patients and found correlations between different risk factors, including age, hemorrhage size, location, and cognitive impairment, which were associated with poor outcomes. The results also showed that Black and Hispanic populations were m...
Researchers developed a compound consisting of insulin bound to an antioxidant group, improving glucose consumption and brain function in mice with type 1 diabetes. The combination therapy showed better cognitive performance than individual treatments alone.
Researchers found that aesthetically appealing experiences trigger fast gamma waves after a one-second delay, indicating active meaning formation. Alpha waves were also observed, reflecting increased attention for high- or low-rated artworks.
A nationwide case-time-control study found that new users of antidopaminergic antiemetics (ADAs) could be at a three-fold increased risk of stroke shortly after treatment started. The risk was highest for metopimazine and metoclopramide, which cross the blood-brain barrier.
A new study led by Kelly Monaghan at West Virginia University suggests that interrupting the immune response may improve multiple sclerosis outcomes. The researchers found that targeting a specific protein called CCL17 can prevent the disease from attacking the central nervous system, leading to milder symptoms and delayed paralysis.
Researchers have identified a novel drug candidate, lonafarnib, that improves neuronal morphological defects, abnormal function, and memory impairments in a mouse model of tuberous sclerosis complex. The study suggests that reducing the levels of active Rheb is crucial for normalizing memory in TSC mice.
A novel system to control protein aggregation in a model of Parkinson’s disease suggests that aggregation of alpha-synuclein plays a critical role in disrupting neuronal homeostasis and triggering neurodegeneration. Light treatment led to formation of Lewy body-like aggregates, neurodegeneration, and Parkinson-like motor deficits in mice.
The American Academy of Neurology recommends using medications such as aspirin and clopidogrel, alongside statins and regular physical activity, to prevent a second stroke in people with intracranial atherosclerosis. This approach is more beneficial than placing a stent in the blood vessel.
Researchers at LSU Health New Orleans and Karolinska Institutet found that intranasal application of pro-resolving lipid mediators arrested memory loss and brain degeneration in an experimental Alzheimer's model. This discovery opens up new possibilities for therapeutic interventions for Alzheimer's disease.
Scientists have created electrodes from recycled coffee grounds that can detect trace levels of biomolecules in vitro, offering a more sensitive surface for neurochemistry detection. The researchers hope to boost their neurochemical detection abilities by fabricating entire electrodes with carbon from coffee grounds.
The study highlights the need to analyze molecular markers, such as genetic sequences or brain proteins, to obtain more accurate assays, diagnoses and therapies. The results show changes in astrocytes attempting to adapt to toxic environments from the disease, worsening its progression.
A recent study found that stimulating reactive astrocytes promotes the elimination of toxic protein aggregates in Huntington's disease. This cooperative mechanism between neurons and astrocytes holds promise for potential treatments.
A study found that microglia's TREM2 receptor is activated up to two decades before Alzheimer's symptoms appear in individuals with a genetic predisposition. This activation may slow cognitive decline and pathological brain changes. The research suggests modulating microglial activity could be a promising therapeutic strategy.