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What happens when cats get fat? Scientists weigh in

Researchers found that as cats gained weight, their gastrointestinal transit time decreased, reducing nutrient extraction. The study also revealed changes in gut microbial composition, with an increase in Bifidobacterium and a decrease in Collinsella, opposite to what has been seen in overweight humans.

SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalJournal of Animal Science·TypeObservational study·DateNov 1, 2023

Light-activated molecular machines get cells ‘talking’

Rice University scientists use light-activated molecular machines to trigger intercellular calcium signals, revealing a powerful new strategy for controlling cellular activity. The technology could lead to improved treatments for people with heart problems, digestive issues, and more.

SourceRice University·JournalNature Nanotechnology·TypeExperimental study·DateJul 10, 2023

Chemical found in common sweetener damages DNA

A new study by North Carolina State University researchers finds that sucralose-6-acetate, a chemical formed when we digest sucralose, is genotoxic and breaks up DNA. The chemical is also present in trace amounts in the sweetener itself, posing potential health risks.

SourceNorth Carolina State University·JournalJournal of Toxicology and Environmental Health Part B·TypeExperimental study·DateMay 31, 2023

Microplastics are harming gut health

A study by McGill University found that microplastic pollution alters the gut microbiomes of seabirds, increasing pathogens and antibiotic-resistant microbes. The research warns humans to be wary of microplastics in their environment and food, as they can also impact human health.

SourceMcGill University·JournalNature Ecology & Evolution·TypeExperimental study·DateMay 24, 2023

Scientists discover microbes in the Alps and Arctic that can digest plastic at low temperatures

Researchers have identified microorganisms in the Alpine and Arctic regions capable of degrading biodegradable plastics at 15°C, including polyethylene, polyester-polyurethane, and polybutylene adipate terephthalate. The discovery could reduce costs and environmental burden associated with enzymatic recycling processes.

SourceFrontiers·JournalFrontiers in Microbiology·TypeExperimental study·DateMay 10, 2023

How diet quality affects the gut microbiota to promote health

A new study from the University of Illinois found that following the Dietary Guidelines for Americans promotes a diverse gut microbiota composition. The researchers analyzed data from the American Gut Project and discovered that individuals with higher diet quality had a greater abundance of beneficial bacteria involved in fiber metabo...

SourceUniversity of Illinois College of Agricultural, Consumer and Environmental Sciences·JournalJournal of Nutrition·TypeData/statistical analysis·DateMay 4, 2023

COVID-19 infections raise risk of long-term gastrointestinal problems

Researchers found that COVID-19 infections are linked to an increased risk of developing liver problems, acute pancreatitis, and other GI disorders. The study analyzed over 14 million medical records and estimated that SARS-CoV-2 infections have contributed to over 6 million new cases of GI disorders in the US.

SourceWashington University in St. Louis·JournalNature Communications·TypeData/statistical analysis·DateMar 7, 2023

Vibrating capsule doubles the ability for constipation sufferers to poop without drugs

A vibrating capsule designed to stimulate the colon has been shown to double the number of complete spontaneous bowel movements in adults with debilitating chronic constipation. The device, which is not a drug and works directly in the colon, showed significant improvement in symptoms such as straining and stool consistency.

Food coloring nanoparticles may affect human gut

Researchers at Cornell University have discovered that metal oxide nanoparticles commonly used as food coloring and anti-caking agents can damage parts of the human intestine. The study, led by Elad Tako, found negative effects on key digestive proteins in chickens injected with the nanoparticles.

SourceCornell University·JournalAntioxidants·DateFeb 15, 2023

UCalgary researchers develop new imaging technique for clearer picture of “brain in the gut”

Researchers have designed a novel imaging and experimental preparation system to record the activity of the enteric nervous system in mice, providing new insights into the complex processes of digestion and waste elimination. The findings suggest that physical distention of the gut controls how the entire neural network is coordinated.

SourceUniversity of Calgary·JournalThe Journal of Physiology·TypeExperimental study·DateFeb 15, 2023

Study links genetic variant to digestive disturbances in patients with Chagas disease

Researchers identified a genetic variant linked to digestive disturbances in patients with Chagas megaesophagus, a disorder characterized by esophageal dilation and loss of motility. The study suggests that increased interferon-gamma production leads to mitochondrial dysfunction, contributing to the development of the disease.

Snacking on almonds boosts gut health

Researchers at King's College London found that eating almonds increases butyrate production, promoting gut health and potentially alleviating constipation. The study also showed improved nutrient intake and a positive impact on the gut microbiome.

SourceKing's College London·JournalAmerican Journal of Clinical Nutrition·DateOct 20, 2022

Tracking down satiety mechanisms in the stomach

Researchers at Leibniz-Institut für Lebensmittel-Systembiologie an der TU München discovered that casein digestion produces peptides with a satiating effect, stimulating gastric acid secretion via bitter receptors. This mechanism may help regulate food intake and maintain a healthy body weight.

SourceLeibniz-Institut für Lebensmittel-Systembiologie an der TU München·JournalJournal of Agricultural and Food Chemistry·TypeExperimental study·DateOct 11, 2022

More than a gut feeling

Research reveals that gut flow velocity directly affects nutrient absorption and bacterial levels, with optimal conditions for each. The study suggests the gut adjusts its flow speed to regulate these processes in response to meal intake or fasting, potentially preventing diseases such as chronic fatigue and poor nutrient absorption.

Issue cover image a new study points to evolutionary causes and ecological consequences of the absence of a digestive enzyme in birds

A new study reveals that birds lost the ability to digest trehalose, a non-reducing disaccharide found in common food sources, likely due to evolutionary divergence from their common ancestor. This loss has significant ecological implications, including reduced access to energy-rich foods and potential adaptations by other species.

SourceUniversity of Chicago Press Journals·JournalPhysiological and Biochemical Zoology·TypeExperimental study·DateJun 3, 2022

Double agents: How stomach stem cells change allegiance upon injury

A molecular switch, p57, enables stomach stem cells to change allegiance from normal digestion to injury response, potentially leading to new treatments for gastric pathologies. The study's findings suggest that p57 is a key regulator of reserve stem cell state in gastric chief cells.

Eating prunes may help protect against bone loss in older women

Prunes have been found to help prevent or delay bone loss in postmenopausal women by reducing inflammation and oxidative stress. This is due to their potential to alter the gut microbiome, which can lead to lower levels of pro-inflammatory cytokines and markers of oxidative damage.

SourcePenn State·JournalAdvances in Nutrition·TypeMeta-analysis·DateFeb 9, 2022

New review suggests coffee consumption can stimulate digestion

A new review suggests that moderate coffee consumption can stimulate digestive processes and help movement through the colon. The study also found a possible association between coffee consumption and reduced risk of gallstones and certain liver diseases. However, further research is needed to confirm these findings.

SourceKaizo·JournalNutrients·TypeLiterature review·DateJan 18, 2022

Chewing to stay slim: how to savor your food better and dodge weight gain, too!

A recent study published in Scientific Reports found that chewing food thoroughly increases energy expenditure through diet-induced thermogenesis (DIT), which helps prevent obesity. The study involved participants who chewed liquid food for varying durations, revealing that prolonged chewing and tasting increased DIT, gas exchange, pro...

SourceWaseda University·JournalScientific Reports·TypeExperimental study·DateJan 12, 2022

Healthier tapioca starch is on the way

Researchers at RIKEN have developed a healthier form of tapioca starch by suppressing multiple genes that increase its resistance to digestion. The resulting starch is composed of longer chains with fewer branches, making it harder to digest and potentially improving intestinal function and blood sugar control.

SourceRIKEN·JournalPlant Molecular Biology·DateDec 16, 2021