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Saliva test to detect GHB and alcohol poisonings

Researchers developed a saliva-based test detecting methanol, ethanol, ethylene glycol, propan 1,3 glycol and γ-hydroxybutyric acid. The test uses gas chromatography-differential mobility spectrometry for accurate detection of toxic levels in saliva samples.

SourceIOP Publishing·JournalJournal of Breath Research·DateJan 7, 2016

Study finds tests used to measure internal bleeding for patients may not be reliable

A recent study found that coagulation tests used to monitor internal bleeding in patients taking blood thinners like Xarelto and Eliquis may not be reliable. The tests, such as prothrombin time (PT), PTT, or INR, were found to be elevated in a minority of cases but appear unreliable to measure the risk of internal bleeding.

SourceNationwide Children's Hospital·JournalAnnals of Emergency Medicine·DateAug 21, 2015

Eating wild, foraged mushrooms can result in liver failure or death as misidentification is common

A case study in Canadian Medical Association Journal highlights the risks of eating wild mushrooms, with a woman requiring a liver transplant after consuming misidentified Aminata bisporigera. The authors emphasize the importance of proper identification and caution against premature discharge from hospital or emergency department.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateJul 13, 2015

A multi-faceted poison

Researchers have developed a mass spectrometry-based process to detect the toxic bacteria's emetic toxin, cereulide. The new method identified 18 variants of cereulide and is being evaluated for its reliability in detecting contaminated products.

SourceTechnical University of Munich (TUM)·JournalAnalytical and Bioanalytical Chemistry·DateApr 1, 2015

A poisonous cure

A team of Michigan State University scientists has discovered an enzyme, called POPB, which converts toxins into cyclic peptides with missile-like precision in the human liver. This breakthrough could lead to single-minded medicines with zero side effects by harnessing the distinct properties of POPB.

Oral chelation for environmental lead toxicity

A study published in PLOS Medicine found that oral chelation therapy with dimercaptosuccinic acid (DMSA) reduced the amount of lead in blood of young children in Zamfara State, Nigeria. The treatment was associated with a significant reduction in venous blood lead levels, and no clinically severe adverse effects were reported.

SourcePLOS·JournalPLOS Medicine·DateOct 7, 2014

Annals of Internal Medicine tip sheet for May 6, 2014

A study published in Annals of Internal Medicine found that Massachusetts' comprehensive health care reform led to a significant decline in deaths, particularly among nonelderly residents. The researchers estimated that the reform prevented 320 deaths per year and saved one life for every 830 persons gaining insurance. Additionally, th...

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·DateMay 5, 2014

Impersonating poisonous prey

Prey animals adopt garish colors to live long and prosper, even if they aren't poisonous. The evolutionary benefit of mimicry works, with predators reacting to the impersonations and avoiding eating the imposters. This study used evolving populations of digital organisms in a virtual world called Avida.

SourceMichigan State University·JournalPLOS ONE·DateMar 10, 2014

Green poison-dart frog varies mating call to suit situation

A study found that green poison-dart frogs vary their mating calls according to the availability of potential mates, adjusting their behavior to balance the risk of predation and securing a mate. In certain contexts, green males appear more conspicuous to females than red males, but less visible to predators.

SourceSpringer·JournalBehavioral Ecology and Sociobiology·DateNov 11, 2013

How to achieve a well-balanced gut

A new study published in PLOS Pathogens highlights the importance of balancing the gut microbiome to prevent food-borne infections. The researchers found that SIGIRR protein plays a critical role in protecting the gut against bacterial pathogens, and its dysfunction can lead to increased susceptibility to colonization by harmful microbes.

SourcePLOS·JournalPLOS Pathogens·DateAug 8, 2013