Articles tagged with Research Impact
Researchers develop unsupervised machine learning algorithm to classify osteosarcoma at diagnosis based on gene expression modules. This approach enables personalized treatment strategies for osteosarcoma patients.
A Swansea University research study has evaluated the long-term environmental impacts of different Japanese knotweed management methods. The study found that glyphosate-based foliar spray control is the most sustainable approach, using the least materials and having the lowest economic costs.
Researchers at Houston Methodist discovered a way to reverse infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein. The study showed that this protein, called serum opacity factor, lowered HDL cholesterol levels by over 40% in three hours and restored fertility in the mice.
A recent study analyzed 7,301 metastatic breast cancer patients with MTAP loss, revealing younger age, higher TNBC cases, and BRCA1 mutations. The findings also suggest potential therapeutic agents targeting PRMT5 and MTA2 in MTAP-deficient cancers.
A population data linkage study found fewer people in Wales diagnosed with long-term conditions in 2020 and 2021 than expected, indicating a potential backlog of undiagnosed patients. This disparity affects chronic obstructive pulmonary disease (COPD) and anxiety disorders, corresponding to over 30 and 80 missing diagnoses respectively.
A study found that telemedicine visits did not adversely affect the quality of care for patients with major depression, and even improved some aspects of care. The transition to virtual visits also led to increased adherence to measurement-based care practices.
A recent study published in JNCCN found that the lack of genomic research for people with African ancestry is hindering efforts to reduce disparities in prostate cancer outcomes. The researchers evaluated molecular genetic results for 113 Black South African men diagnosed with advanced prostate cancer, identifying 17 pathogenic and pot...
The March issue of CHEST journal features 44 articles on topics such as asthma, critical care, and sleep medicine. The journal also includes complementary web resources, including visual abstracts.
Researchers developed a new AI-driven method to detect and predict defects in 3D printed metals, enabling rapid improvements in additive manufacturing. The method uses X-ray imaging and machine learning to identify pore generation in real-time with near-perfect accuracy.
The study estimates that tap water scald burns result in significant healthcare costs, with average costs of $572 per emergency department visit and $28,431 per hospital stay. Thermostatic mixing valves could reduce the risk of these burns by mixing hot water with cold water.
Researchers found that suppressing AMPKα1 but not AMPKα2 isoforms improved aging-related impairments in mice. The study revealed novel insights into the roles of AMPK signaling pathway in cognitive aging.
The study found that phenolic extracts from roselle inhibited fat cell formation by 95%, while hydroxycitric acid had no effect. Researchers hope the plant's antioxidants can be used in health food products to manage obesity without side effects.
Researchers have uncovered the ancient roots of a gene in wheat that provides resistance to the devastating Wheat Yellow Mosaic Virus, which causes significant economic losses. The discovery could lead to more resistant wheat cultivars, increased crop yields, and reduced use of harmful fungicides.
Research on caregiving after neurotrauma and neurological disability emphasizes the need to address unmet caregiver needs, which can impact the quality of care provided. Studies found that brain injury caregivers experience higher burden, decreased physical and neuropsychological functioning, and lower mental health.
The University of Missouri will receive a $10 million grant from the USDA National Institute of Food and Agriculture to double cover crop seed production in the US by 2030. The project aims to educate farmers about new varieties of cover crops, examine their performance with root growth, and distribute them nationwide.
The NCCN Annual Conference will debut a new hybrid format featuring in-person events at a new venue, allowing for hallway conversations and networking opportunities. The conference will also showcase more than 100 abstract poster presentations on various oncology-related categories.
A new Argonne study compares drone energy usage to diesel trucks and electric vehicles, finding that drones consume as much energy as either on average windy days. The models are based on regional energy consumption and facility costs of direct delivery drones under various wind speed scenarios.
A systematic review of Cognitive Functional Therapy found it to be no better than traditional therapies in reducing pain and disability in people with chronic low back pain. The researchers call for future trials featuring blinded participants and larger sample sizes to improve current evidence.
The American Roentgen Ray Society (ARRS) has awarded four radiologists with the 2023 Resident/Fellow in Radiology Awards for their exceptional research, education, and administrative work. Drs. Elliot T. Varney, Vincius Alves, Luca Pasquini, and Pallavi Srivastava will present their research findings at the upcoming ARRS Annual Meeting...
A study by MedUni Vienna's Center for Public Health used GPT-3 to analyze the potential of AI in addressing societal megatrends, including digitization, urbanization, and climate change. The findings suggest that AI can improve understanding of these complex issues and provide suggestions for solutions.
The war in Ukraine may trigger a new global land race, threatening rural livelihoods and the environment. Large-scale land acquisitions could exacerbate conditions of water scarcity and land degradation, prompting concerns about policy implications and long-lasting effects on rural development.
A three-year effort to conserve bee populations showed positive effects, with increased bee abundance and diversity in studied areas. However, quality of the habitat played a key role in these positive effects, and its impact on maintenance over time was also significant.
A decade-long international study has linked genetic changes in kidney cancer to patient outcomes, identifying four groups of patients based on specific genes. The findings suggest that tumour DNA sequencing may provide a more effective way to predict patient risk of kidney cancer recurrence.
A recent study found that metformin users had distinct DNA methylation profiles compared to non-users, potentially revealing its role in longevity. The research identified several pathways related to delirium and aging, highlighting the need for further investigation into metformin's mechanism of action.
Researchers at Gladstone Institutes found that ApoE4 from neurons plays a critical role in Alzheimer's disease, contrary to previous focus on glial cells. The study shows that deleting ApoE4 from neurons reduces brain changes resembling Alzheimer's disease, offering new possibilities for treatment.
The ENIGMA Initiative aims to bridge knowledge gaps on brain aging factors in developing countries, particularly in India. The study will collect comprehensive data on risk and protective factors through clinical interviews, bloodwork, and brain MRI to identify universal and population-specific predictors of dementia.
Scientists have created a non-destructive method to detect and differentiate gibberellins, a class of plant hormones crucial for growth. The new nanosensors can identify changes in GA levels across various plant species, enabling early interventions against salinity stress.
A recent study found that mothers struggling with depression tend to respond slower to their child during back-and-forth dialogue. This delayed response time may have long-term impacts on children's language development and academic outcomes.
Researchers developed a testing model to understand cognitive challenges of superior semicircular canal dehiscence (SSCD), a rare condition causing sound-induced dizziness and hearing abnormalities. The Mongolian gerbil model shows promise for accelerating recovery with reversible diagnostic findings characteristic of patients with SSCD.
The Brain Canada Foundation and the Canadian Institutes of Health Research have invested $663,000 in two groundbreaking projects: REBALANCE and HiCALS. REBALANCE explores focused ultrasound as a potential treatment for Alzheimer's disease, while HiCALS investigates the link between high-fat diets and ALS survival.
The addition of antioxidants to cell cultures can improve the production of monoclonal antibodies by reducing oxidative stress and increasing cell viability. This has potential benefits for therapies targeting cancer and autoimmune diseases.
Researchers have developed a novel prognostic index to predict survival outcomes in gastric cancer patients. The inflammation-combined prognostic index (ICPI) combines three biomarkers - lymphocyte-to-monocyte ratio, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio - to provide a personalized prognosis for each patient.
The University of Canterbury researchers found that rocket launches emit gases and particulates that damage the ozone layer. The study highlights the need for coordinated global action to protect the upper atmosphere environment.
A Texas A&M University study found that an intervention program increased physical activity in older rural women, leading to improved quality of life and reduced health risks. The Strong Hearts, Healthy Communities 2.0 program was successful in increasing exercise levels at both 12 and 24 weeks.
Researchers have discovered licorice leaf extract as a potent bactericide and fungicide, offering a sustainable alternative to synthetic pesticides. The extract modulates plant immune responses to pathogens and acts against resistant oomycetes, making it a potential solution for naturally controlling plant diseases.
The grant aims to eliminate barriers and facilitate access to early phase cancer clinical trials for medically underserved communities. Researchers will develop and implement a multilevel program to improve referrals and enrollment, exploring the impact of remote clinical trials on enhancing diversity in trials.
Researchers highlight CD200's role in regulating immunosuppressive tumor microenvironments and propose alternative strategies for its neutralization. Unbiased genomic- and proteomic-based approaches may help clarify CD200 expression regulation across various human cancers.
A nationwide Finnish study found that around 58% of people with low educational attainment by age 30 will have a diagnosis of a mental disorder by age 52. The study also showed a stronger association between lower socioeconomic position and later diagnoses of substance misuse or schizophrenia spectrum disorders.
A new study suggests that current coal exit efforts are unlikely to succeed without stronger policies, including carbon pricing and phase-out of coal mining. China plays a critical role in achieving this goal, as it produces and consumes over half of global coal, and its swift action can help propel Paris-aligned momentum.
A recent study published in BMJ Open Sport & Exercise Medicine suggests that golf may be just as healthy or even healthier than Nordic walking for older adults. The research compared the acute effects of three aerobic exercises: an 18-hole round of golf, 6km of Nordic walking, and a 6km walk. The results showed that all three types of ...
New research from Center for BrainHealth demonstrates the positive impact of online Strategic Memory Advanced Reasoning Tactics (SMART) training on mental health symptoms. The study found improvements in depression, anxiety, and stress symptoms in healthy adults, with lasting effects six months post-training.
A new study found Black South Africans who migrated to find work reported better emotional well-being and were at lower risk for depression after the move. The research may help policymakers tailor mental health resources to underprivileged migrants and those seeking economic mobility.
Researchers from Purdue University have received funding from the Trask Innovation Fund to develop and test their innovations. The awards will support projects in various fields, including plant phenotyping, genome editing, and radiative cooling paints, aiming to enhance commercial value and industry applications.
Researchers found that electric car adoption in California was associated with real-world reductions in air pollution and asthma-related emergency room visits. The study also highlighted an 'adoption gap' between low-resource zip codes, pointing to opportunities for environmental justice.
A new study published in the Journal of the American Heart Association found that people hospitalized for sepsis are at a higher risk of heart failure and rehospitalization within 12 years. The researchers analyzed data from over 2 million adults who survived non-surgical hospitalizations between 2009 and 2019.
Dr. Ruth Ann Marrie has made significant contributions to multiple sclerosis research, including the discovery of comorbidities' impact on MS evolution and development of personalized medicine strategies. Her work aims to improve quality of life by stopping and preventing MS through early intervention and targeted treatments.
Researchers identified 7 key symptoms of long COVID, including heart issues and joint pain, in a study of 52,461 patients. The findings could help healthcare providers diagnose and treat the condition more effectively.
Etoposide's impact on DNA structure has been untangled by Cornell researchers using optical tweezers and magnetic tweezers. The study found that etoposide promotes DNA loop trapping and barrier formation by topoisomerase II, enabling the creation of sensitive screening tools for improving patient treatment.
Research from Cornell University finds that replacement work-from-home (working during regular hours) boosts psychological well-being and engagement, while extension work-from-home (working outside of regular hours) leads to lower well-being, higher turnover intentions, and conflict between work and family. Women are particularly affec...
A new study published by the University of Leeds reveals that people with arthritis are 20% less likely to be in work compared to their peers without the condition. The most striking finding is that non-university educated women aged 60-plus are at least 37% less likely to be in work if they have arthritis.
The Chan Zuckerberg Initiative grant will support advanced imaging training for over 2,000 scientists through a combination of hands-on events and online resources. Array tomography, an imaging technique that offers higher resolution and detailed molecular labeling, will be a key focus of the project.
A randomized controlled study found significant reductions in both burnout and depression symptoms among academic physicians who practiced Transcendental Meditation. The technique produced large effect sizes in decreasing burnout and depression symptoms, with improvements also observed in emotional exhaustion and personal accomplishmen...
A team of researchers is using the Frontera supercomputer to develop medium to long-term fishery forecasts driven by high-resolution coupled climate forecasts. They find that changes to upwelling are predicted to be warmer, not colder, and may impact the sustainability of fisheries in the US and globally.
Research from Texas A&M University reveals that male alcohol use has a significant negative influence on in vitro fertilization (IVF) success rates. The study highlights the importance of expanding fertility and prepregnancy messaging to emphasize the reproductive dangers of alcohol use by both parents.
Researchers examined factors that led to discriminatory lending decisions in Ohio's 1930s loan applications, finding neighborhoods with Black families were 40 times more likely to be redlined. The study highlights ongoing consequences of racist policies, including poverty and life-expectancy disparities.
The number of cardiovascular disease-related deaths in the US rose significantly between 2019 and 2020, with Asian, Black and Hispanic populations most affected. The largest single-year increase since 2015 was seen in CVD deaths among these populations, highlighting structural and societal disparities.
A comprehensive study found that up to 82 percent of Berlin's vegetable demand could be met locally if all available land was used for urban gardening. Investing in water and human resources would be crucial for this production, with a total investment cost of 753 million euros required.
A new study by University of Georgia researcher Shane Singh found that mandatory voting laws increase voter turnout when enforced, not the severity of the law. Turnout can increase by nearly 20 points with credible sanctions, compared to 8-10 points without them.
USC researchers found that music education benefits adolescents' wellbeing, boosting hopes for the future and positive development. Younger students received musical training scored higher in key measures of positive youth development.
A large Danish population study found that premature birth before 34 weeks is linked to lower scores in maths and language tests as a teenager. However, the researchers noted that cognitive outcomes are not predetermined at birth but are heavily influenced by social circumstances.