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CNIC scientists uncover opposing roles of p38 proteins in cardiac hypertrophy

A study by CNIC scientists has identified a key role for the MKK3/6–p38γ/δ signaling pathway in cardiac hypertrophy. Inhibition of p38α promotes an unexpected activation of the other branch of the pathway, consisting of the proteins MKK3, p38γ, and p38δ. This activation induces another key pathway in cardiac hypertrophy, the mTOR pathway.

Towards higher nanopatterning resolution with molecules that fill nanogaps better

A research group from Tokyo University of Science has discovered molecular features that govern the filling process at nanoscales, enabling finer resolutions in ultraviolet nanoimprint lithography. The findings provide valuable insights for guiding the selection and design of optimized resists for sub-10 nm resolution.

SourceTokyo University of Science·JournalNanomaterials·TypeComputational simulation/modeling·DateAug 8, 2022

Future-proofing the Great Lakes region through climate research: Improved regional climate models will help the Great Lakes Region become more informed, ready and resilient

A new study uses high-resolution regional model experiments to explore how lake surface temperatures may affect the climate of the Great Lakes region. Small differences in lake surface temperatures can have a significant impact on summer climate and fuel extreme weather events.

SourceDOE/Argonne National Laboratory·JournalJournal of Geophysical Research Atmospheres·DateAug 3, 2022

Clever COVID-19

MU researchers have identified specific mutations in the Omicron variant's spike protein that help it evade existing antibodies from vaccines or previous COVID-19 infections. These findings can inform developers of COVID-19 treatments and vaccines, which may need to target different parts of the virus to produce effective outcomes.

SourceUniversity of Missouri-Columbia·JournalInternational Journal of Molecular Sciences·TypeMeta-analysis·DateJul 18, 2022

DOE backs Rice physicists’ collaboration

Rice University physicists Frank Geurts and Wei Li have received a $1.8 million grant from the Department of Energy to conduct research on relativistic heavy-ion physics at both Brookhaven National Laboratory and the Large Hadron Collider at CERN. Their work focuses on creating quark-gluon plasmas, a

Let machines do the work: Automating semiconductor research with machine learning

Researchers use machine learning to automatically analyze Reflection High-Energy Electron Diffraction (RHEED) data, enabling faster and more efficient discovery of new materials. The study focused on surface superstructures in thin-film silicon surfaces and identified optimal synthesis conditions using non-negative matrix factorization.

SourceTokyo University of Science·JournalScience and Technology of Advanced Materials Methods·TypeExperimental study·DateJun 16, 2022

German Research Foundation approves funding for excellent research in JGU’s core research areas

The German Research Foundation has granted funding to Johannes Gutenberg University Mainz (JGU) and its strategic alliance partners for four years. Researchers in materials sciences, biophysics, and medicine are working on three collaborative projects with a total funding volume of EUR 35 million. The focus is on developing multiscale ...

A novel path for sustainable photon upconversion with non-precious metals

Researchers from Johannes Gutenberg University Mainz have achieved a breakthrough in using chromium compounds for efficient green-to-blue photon upconversion. This process can expand the use of low-energy sunlight in solar cells and photochemical reactions, reducing environmental impacts associated with rare metal extraction.

SourceJohannes Gutenberg Universitaet Mainz·JournalAngewandte Chemie International Edition·DateJun 3, 2022

High fat diet, unregulated athletic exercise endurance enhancers linked to risk of pancreatic cancer

A study found that high fat diets and synthetic substances in unregulated athletic performance enhancers can activate a receptor accelerating the progression of pre-cancerous lesions to pancreatic cancer in mice. Limiting exposure to these substances may help prevent pancreatic cancer development.

SourceMichigan Medicine - University of Michigan·JournalNature Communications·TypeExperimental study·DateJun 1, 2022

Addressing racial gaps in NIH grant funding

Racial gaps in NIH grant funding are attributed to the subjective review process and lack of diversity among reviewers. The NIH has proposed initiatives to address these disparities, including appointing diversity officers and allocating funding for research on health equity and health disparities.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateMay 25, 2022