A new study found that the Fuster-BEWAT score accurately predicts cardiovascular risk in healthy individuals, even without blood analysis. The score uses five health indicators: blood pressure, physical activity, BMI, fruit and vegetable intake, and smoking status.
Reservoirs of oxygen-rich iron between the Earth's core and mantle may have played a major role in shaping our planet's history. The discovery suggests that massive iron dioxide rocks could be generated annually above the core, releasing oxygen into the atmosphere, potentially triggering the Great Oxygenation Event.
Suture ligation is a common but ineffective treatment for polydactyly, often requiring corrective surgery due to complications such as painful neuromas and infection. Surgical excision is considered a more effective option with fewer risks and less scarring.
A global study of over 5,000 patients found that restrictive blood transfusion practices are safe and effective, reducing deaths, heart attacks, strokes, and kidney failures. The study also reduced the number of transfusions by 28% and the amount of blood transfused by 30%.
La Jolla Institute researchers find Histamine-Releasing Factor (HRF) exacerbates both asthma and food allergies. Inhibiting HRF may prevent allergic reactions, offering a new treatment avenue.
Researchers at MIT have created a new delivery system for the CRISPR genome-editing system, using nanoparticles to target and delete disease-causing genes. The technique achieved an 80% success rate in deleting the Pcsk9 gene, which regulates cholesterol levels, resulting in a 35% drop in total cholesterol levels.
Scientists discovered a new cell signaling pathway governed by Notch signaling protein that keeps blood vessels intact, which could lead to better drug development and reduce side effects of cancer and cardiovascular treatments. The new pathway operates through a different mechanism than the protein's known transcription-based pathway.
Researchers at Lund University found that large ears increase air resistance in bats, making flight less energy-efficient. However, they also provide better hearing and generate more lift, which is crucial for echolocation. The study suggests that evolution has made a compromise between flying efficiency and optimal echolocation ability.
Researchers found that sitting in or standing near a charging Tesla port did not trigger a shock or affect defibrillator performance. The study's findings suggest electric vehicles are safe for individuals with cardiac defibrillators, according to the principal investigator.
Researchers analyzed anonymous Google location data to understand human mobility patterns before and after Hurricane Maria. Travel out of Puerto Rico increased by 20% the day before the storm, with people flocking to cities like Orlando and Miami for shelter.
CANDLE, a scalable deep learning framework developed by Argonne's Exascale Deep Learning and Simulation Enabled Precision Medicine for Cancer project, was recognized with the award. The framework has achieved impressive results, including explaining over 92% of variance in drug response.
A £200,000 research project aims to enhance ballistics evidence with similar scientific accuracy as DNA analysis. The LOQUITUR project will develop software to measure minute surface details on ammunition and weapons, enabling more accurate matches and improving forensic analysis.
A new study of patients who underwent laser treatment to vaporize floaters found a very low complication rate and significant improvement in vision. Most patients reported no complications and experienced improved vision after the procedure.
The new software, called Scallop, can reconstruct complete RNA transcripts from fragments of RNA sequences with improved accuracy. This advancement will help scientists better understand the regulation of gene expression.
A new analysis found that when low-income adults were newly covered by Medicaid under the Affordable Care Act, they were more likely to quit smoking cigarettes than their counterparts in states without Medicaid expansion. Smoking cessation programs provided through Medicaid led to a significant increase in quitting rates.
A new study from the University of Eastern Finland supports earlier findings that omega-6 fatty acids do not increase inflammatory responses. The research found that a high serum linoleic acid level is associated with lower CRP levels, suggesting that linoleic acid may actually alleviate inflammation.
A new scanning wave photopolymerization technique allows for arbitrary alignment of liquid crystals with fine control over large areas without the need for strong dyes or additional processing steps. This method enables the creation of highly functional organic materials with arbitrary molecular alignment patterns on the nanoscale.
Adults with treated HIV experience cognitive decline and smaller brain volumes, but effective therapy may halt progression. Brain changes were observed even after two years of treatment, highlighting the importance of monitoring viral suppression in HIV patients.
Researchers from the University of Leeds found two genetic variants in non-invasive bladder cancer tumours, which could lead to more personalized therapy. The study also revealed that women are more likely to have a defect in a specific tumour suppressor gene, opening up new avenues for research.
A new system using thousands of Raspberry Pi nodes brings a powerful HPC testbed to system-software developers and researchers, enabling them to work on large supercomputers without dedicating expensive machine time. The scalable clusters have applications in education, internet of things, and HPC network topology research.
Researchers linked major cholera outbreaks to Asian origin, highlighting need for targeted control strategies. Genomic analysis identified antibiotic-resistant strains originating from South Asia.
Researchers at the University of Birmingham identified two previously unknown mechanisms that bacteria use to protect themselves from antibiotics. The discovery provides new insights into how bacteria develop resistance and could lead to the development of new drugs to combat bacterial infections.
Researchers used Facebook ads targeted at users' personality traits, showing up to 1.4 times more clicks and 1.5 times more product purchases than non-targeted ads. The study suggests that psychological targeting is an effective approach to digital mass persuasion.
The NSF grant aims to improve the properties of magnetic shape-memory alloys, enabling efficient and economical production of magnetic actuators used in various industries. The researchers will use binder jet printing to enhance the microstructure and properties of these alloys.
Columbia University's SCRIPTS system uses AI to process documents in low-resource languages, providing summaries and translations. The project aims to enhance efficiency for intelligence analysts worldwide.
Measuring hsCRP levels after canakinumab treatment identifies individuals likely to see greatest improvements from continued therapy. Patients with lower hsCRP levels after a single dose experience significant reductions in cardiovascular and all-cause mortality.
Studies show that gut-derived metabolites may prevent neurodegeneration, while probiotic treatment corrects memory problems in an Alzheimer's mouse model. The research suggests targeting the gut could be a promising angle to tackle brain disorders across the lifespan.
Researchers tested participants 24 months after a decade-long memory test, finding they recognized 55% of the original images. The study suggests three exposures are sufficient for long-term image recognition.
Researchers found a decreased risk of heart failure by 7 percent and stroke by 8 percent with every additional cup of coffee consumed per week compared to non-coffee drinkers. Machine learning analysis also identified red-meat consumption as a potential risk factor, although the association was less clear.
Researchers identified a reversible 'master switch' that regulates developmental genes in fruit flies, providing a conceptually simple explanation for how different cell types are formed. This discovery could lead to a better understanding of cancer mutations and the development of new therapeutic strategies.
A recent NIH study found that obese pregnant women are more likely to give birth to large infants, with fetuses experiencing longer bones and higher birth weights. This increased fetal growth may predispose these infants to obesity and cardiovascular disease later in life.
A study models the effects of removing farmed animals from the US agricultural system on food production and greenhouse gas emissions. Removing animals resulted in increased food availability, but also led to nutrient deficiencies and reduced GHG emissions by 28%. The removal of animals had unintended consequences on the food supply
A new study finds that a simple tool, Fuster-BEWAT score, can predict cardiovascular risk in healthy individuals using five health indicators: blood pressure, physical activity, body-mass index, fruit and vegetable intake, and smoking status. The Fuster-BEWAT score is as effective as the American Heart Association-recommended ICHS index.
A new study published in Personality and Individual Differences found that high cognitive ability is not a safeguard against believing in conspiracy theories and paranormal phenomena. People with strong motivation to form rational beliefs can still fall prey to these unfounded ideas.
Scientists are sounding the alarm on climate tipping points, warning that the planet is approaching critical thresholds that could lead to abrupt and irreversible changes in the Earth system. The World's top climate scientists have released a statement emphasizing the need for rapid action to avoid these tipping points.
Researchers developed a novel gene therapy that lasts for over eight months, reducing methamphetamine in the brain and its stimulant effects. The therapy generates antibodies against meth, preventing it from reaching the brain.
A pilot study in northeastern British Columbia detected high concentrations of muconic acid, a degradation product of benzene, in the urine of pregnant women. The median concentration was approximately 3.5 times higher than in the general Canadian population, raising concerns about the health impacts of living near fracking sites.
The number of people with Parkinson's disease is expected to grow to 14.2 million by 2040 due to increasing life expectancy and population aging. The medical community must mobilize to respond to this growing public health threat, advocating for increased research funding, access to care, and affordable treatments.
Research finds that workplace bullying and violence increase the risk of type 2 diabetes for both men and women. The study, published in Diabetologia, suggests that these negative interpersonal relationships can activate stress responses and contribute to metabolic changes and obesity.
A new blood test can accurately predict which patients are at risk of liver damage from paracetamol overdose, enabling targeted treatment and reducing hospital stays. The test detects three specific molecules associated with liver damage, allowing for earlier intervention and more effective care.
A team of over 15,000 scientists from 184 countries warns of severe consequences for human well-being due to negative environmental trends. The authors propose steps to reverse these trends, including establishing nature reserves and promoting renewable energy.
A research team from the University of Cincinnati has developed a consensus model of human apolipoprotein A-I, a key component of HDL, which could lead to new strategies for increasing good cholesterol. This breakthrough was achieved through collaborative effort and innovative use of indirect experimental techniques.
A new technique for synthesizing thiophene derivatives has been developed, offering a convenient and effective two-step procedure. The compounds exhibit promising photophysical properties, including fluorescence, making them suitable for various applications, including OLEDs and potential biomedicine uses.
Researchers discovered that T cells can thrive in oxygen-depleted environments when equipped with growth factor VEGF-A. This adaptation allows them to kill cancer cells more effectively, contrary to previous assumptions.
The Phase II study demonstrated an overall response rate of 60%, including partial responses in 12% and stabilization of the disease in 48% of cases. Median progression-free survival was also achieved at 3 months, with manageable adverse effects related to myelosuppression.
Researchers have developed a synthetic system for energy gathering, conversion, and transport inspired by natural photosynthesis. The system uses DNA nanotechnology to spatially control and organize chromophores, mimicking the arrangement of densely packed chromophores in plants and photosynthetic bacteria.
Global carbon dioxide concentrations reached a record 403 parts per million in 2016, and are expected to increase by 2.5 parts per million in 2017. The United States and European Union are projected to see slight declines in emissions this year, while China's emissions are expected to grow by approximately 3.5 percent.
The NIH has awarded $2.34 million to the Global Biological Standards Institute (GBSI) for a five-year educational project to improve research reproducibility. The project, PREPaRED, will train students in reverse experimental design and create freely-available online curricular materials.
Researchers from RIKEN discovered a way to control the properties of north and south poles in frustrated magnets using monopole currents. The system's conductivity can be controlled by applying magnetic fields, enabling efficient magnetism control with minimal energy loss.
Researchers have successfully created mini biological models of human primary liver cancers, known as organoids, in the lab. These tiny laboratory models were used to identify a new drug that could potentially treat certain types of liver cancer, showing promising results for personalized medicine and reducing animal usage.
The GuidAge study suggests that memory complaints reported by elderly individuals can predict a decline in cognitive performance. Five specific items on the McNair and Kahn Scale were found to be statistically significant, including difficulty remembering phone numbers, appointments, and instructions.
Researchers developed a new remote-sensing method to map functional diversity of forests from small to large scales, independent of predefined vegetation units or species information. This allows for the assessment of forest health, resource use efficiency, and adaptation to environmental conditions.
New research by UNC Chapel Hill shows that global GHG reductions will significantly benefit US air quality and human health in 2050. Foreign GHG mitigation efforts contribute substantially to reduced deaths from PM2.5 and O3-related mortality, with co-benefits estimated at $137 per ton CO2.
A team of researchers from LMU and TUM used supercomputing resources to simulate a massive earthquake with 1,500km of non-linear fracture mechanics, achieving a 13-fold improvement in time to solution. The simulation helped understand the complex process behind megathrust earthquakes, which can unleash violent tsunamis.
Researchers have developed a novel approach to combat cancer using synthetic designer cells that mimic T-cells. These cells can detect and kill cancer cells while minimizing side effects, offering a promising new treatment option.
Astronomers study distant galaxy's gravitational lensing, revealing smaller-than-thought giant clumps. Groundbreaking observations and simulations confirm turbulent nature of distant galaxies.
A study by New York University researchers found that when we encounter low-valued items, we're willing to pay more for products later seen; conversely, high-valued items lead to lower prices. This previously undetected factor affects consumer behavior and suggests adaptation is a universal feature of cognitive information processing.
A team of researchers discovered a female alligator snapping turtle in Clear Creek, Union County, Illinois, after 30 years of absence. The 22-pound, 15-inch long turtle is believed to be at least 18 years old and not one of the released turtles.
Researchers analyzed birth and school records to examine environmental moderation of genetic influence on cognitive ability. They found no evidence supporting increased genetic influence in socioeconomically advantaged children.
A Tel Aviv University study found that people often project their own experiences with stress onto colleagues, causing miscommunication and missed opportunities. The research showed that a person's individual stress mindset colors their perception of others' health, productivity, and burnout levels.