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Science News Archive February 2025 - Page 22


Page 22 of 44

Estrogen partially restores progesterone production and ovarian health in mice with lysosomal storage disorder

A recent study found that estrogen can partially restore progesterone levels and improve ovarian health in Mcoln1−/− mice, a model for human mucolipidosis type IV. The research also showed that hormone therapies including estrogen improved luteal cell morphology and lysosomal function.

SourceShanghai Jiao Tong University Journal Center·JournalReproductive and Developmental Medicine·DateFeb 17, 2025

Researchers map brain development at the protein level in unprecedented detail

The study analyzed over 24 million individual cells from mouse brains, revealing detailed molecular pathways that guide brain development. The research team discovered two distinct developmental pathways for oligodendrocytes and offered new insights into how different brain cell types emerge and mature.

Sliding down

Researchers discover that disordered solids lose stability at low-frequency vibrations near zero, leading to a 'loose state' where particles slide in clusters. The theory applies to materials with negligible thermal fluctuations, including those found in space.

Breakthrough observation of real-time protein translocation by SecYEG-SecA complex

A team of researchers from Japan directly visualized protein translocation across membranes for the first time, providing insights into the SecYEG-SecA complex dynamics and its role in facilitating protein movement. The study estimated a protein translocation rate of 2.2 amino acid residues per second.

SourceNara Institute of Science and Technology·JournalNature Communications·TypeImaging analysis·DateFeb 17, 2025

Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential

Researchers developed push-pull azobenzenes that interact with the lipid bilayer and induce light-dependent membrane potential changes. The molecules' ability to partition into membranes and undergo isomerization allows for precise modulation of surface charge, enabling non-invasive cell stimulation.

Children with ARFID face increased risk of disease

A new study found that children with avoidant restrictive food intake disorder (ARFID) are at a higher risk of developing intellectual disability, autism, gastro-oesophageal reflux disease, epilepsy, and chronic lung diseases. They also experience more medical diagnoses and require longer hospital stays than other children.

SourceKarolinska Institutet·JournalJAMA Pediatrics·TypeObservational study·DateFeb 17, 2025

Older patients can inadvertently be put at risk when they are taken off blood-thinning drugs

A study by University of Bath researchers found that stopping anticoagulants for patients aged 75 and over does not significantly affect the risk of major bleeding, but increases the risk of serious events like stroke and death. This highlights the need for clinicians to carefully consider the risks of stopping anticoagulation therapy ...

SourceUniversity of Bath·JournalHeart·TypeObservational study·DateFeb 17, 2025

WVU research shows buyers believe karma, not boycotts should punish brands for bad behavior

Research by West Virginia University expert Kylie Vo found that consumers who believe in karma are more likely to forgive companies that behave immorally and less likely to boycott them. In contrast, non-moral transgressions like defective products or misleading claims can severely damage consumer-brand relationships and brand value.

SourceWest Virginia University·JournalJournal of the Association for Consumer Research·DateFeb 17, 2025

How staphylococcus aureus ‘steals’ iron from our blood during infections

Researchers have mapped the full sequence of protein-protein interactions during iron extraction by Staphylococcus aureus, opening possibilities for developing new treatments. The study used TR-XSS technique to observe the dynamics of IsdB-Hb complex formation and found that iron is extracted only when both Hb chains are bound to IsdB.

SourceEuropean Synchrotron Radiation Facility·JournalNature Communications·TypeExperimental study·DateFeb 17, 2025

The fire paradox: Tree-ring data shows wildfire activity has declined, not increased

A study published in Nature Communications shows that widespread wildfires were frequent about every 10-20 years in many areas, but severe fires have increased due to natural fire cycles being disrupted. The data suggests that the prevalence of non-fire years has led to denser forests and hotter, more destructive wildfires.

SourceUniversity of Arizona·JournalNature Communications·TypeData/statistical analysis·DateFeb 17, 2025

Light from artificial atoms

Researchers at TU Wien and ISTA have developed artificial atoms made of superconducting circuits that can be tuned to specific energy values. These 'artificial atoms' enable the storage and retrieval of light, opening up new possibilities for quantum experiments.

SourceVienna University of Technology·JournalPhysical Review Letters·TypeExperimental study·DateFeb 17, 2025

New remotely-delivered support programme could deliver excellent care while saving the NHS and social care an average of £9000 a year for each person with dementia

A new remotely-delivered support programme, NIDUS-Family, has been shown to improve the lives of people with dementia while reducing healthcare costs. The programme uses goal setting and personalized care to help individuals live well at home for longer, resulting in cost savings of £8934 per person over one year.

SourceQueen Mary University of London·JournalThe Lancet Healthy Longevity·TypeRandomized controlled/clinical trial·DateFeb 17, 2025

Study findings raise questions about the inclusion of sepsis bundle in the CMS value program

A systematic review found no moderate-to-high level evidence that compliance with the Centers for Medicare & Medicaid Services' (CMS) Severe Sepsis and Septic Shock Management Bundle was associated with improved sepsis mortality. The study suggests reconsidering the inclusion of the bundle in the Hospital Value-Based Purchasing program.

SourceAmerican College of Physicians·JournalAnnals of Internal Medicine·TypeNews article·DateFeb 17, 2025

Study reveals surge in gambling addiction following legalization of sports betting

A new study reveals a dramatic increase in sports betting and gambling addiction help-seeking since the Supreme Court legalized sportsbooks in 2018. Online sportsbooks have had a substantially greater impact on this issue than traditional brick-and-mortar sportsbooks, with nationwide searches for help increasing by 23% nationally.

SourceUniversity of California - San Diego·JournalJAMA Internal Medicine·TypeObservational study·DateFeb 17, 2025

Inadequate postpartum screening for hypertension and diabetes a ‘missed opportunity’ for women, study suggests

A new study published in Circulation suggests that less than one in five patients are tested for cardiovascular risk factors following pregnancy-related hypertension or diabetes. This leaves women without adequate screening for high blood pressure, lipids, and sugars, increasing their risk of future stroke or heart disease.

SourceInstitute for Clinical Evaluative Sciences·JournalCirculation·TypeObservational study·DateFeb 17, 2025