The FDA has approved cabozantinib as a standard of care treatment for patients with previously treated advanced neuroendocrine tumors. The drug showed improved efficacy in reducing tumor growth and improving patient survival compared to placebo.
A study of over 14,600 Norwegian veterans found that taking a life in combat had no subsequent impact on their mental well-being. In contrast, veterans who served in Lebanon experienced increased mental health problems and reduced quality of life after killing someone in combat.
Researchers at Lancaster University discovered a new type of vaccine-specific scepticism, where some people perceive COVID-19 vaccines as 'not a vaccine' compared to MMR. This phenomenon may also apply to the flu vaccine, highlighting the need for clear public health messaging.
A study published in iEnergy found that strategically locating data centers in western China can reduce carbon emissions. By shifting 33% of computational load from Eastern China to the West, overall carbon emissions are reduced by 26%.
A new study from Queen Mary University of London reveals substantial financial burdens on patients and concerns over the reliability of information in the fertility sector. The research highlights a need for regulatory action to ensure clinics provide accurate cost information and treatment options.
Researchers developed a tiny magnetic robot that can take 3D scans from deep within the body, enabling 'virtual biopsies' for non-invasive cancer diagnosis and treatment. The device uses high-frequency imaging to create detailed 3D reconstructions, allowing clinicians to diagnose and treat colorectal cancer in a single procedure.
A study found that open-label placebos alleviated symptoms of premenstrual syndrome (PMS) in women, with effects greatest when provided with additional information. The placebo effect played a significant role, accompanied by improved self-efficacy and reduced symptom intensity.
Researchers are developing soft-bodied actuators, shape-adaptive propulsors, and AI-driven control strategies to improve energy efficiency and adaptability in MURs. Future innovations may enable robots to mimic marine organisms with unprecedented fluidity and facilitate swarm robotics for collective exploration.
A large cohort study found living alone to be a critical factor in suicide risk assessments for individuals with depression and anxiety. The study of 3.7 million individuals highlighted the importance of preventing mental illness while addressing living arrangements.
Researchers found people in Japan are less likely to exploit cooperative AI agents compared to humans, while Westerners take advantage of robots more often due to guilt over human exploitation. Cultural differences may shape the future of automation.
A new study from York University combines fluid mechanics and chemistry to understand the Earth's early evolution. Researchers found that the lower mantle's structure was established four billion years ago, with most crystals forming at low pressure, leading to a different chemical signature than previously thought.
Researchers at City of Hope discovered that mutated cells can persist for years without becoming cancer and require an additional inflammatory push for malignancy to occur. Chronic inflammation is a key trigger for tumor formation, making it essential to avoid situations like high-fat diets and obesity.
A new study in Health Data Science identifies individuals with both cardiovascular and musculoskeletal conditions as a distinct high-risk group. These 'osteo-cardiovascular fallers' face a higher risk of severe falls and death compared to healthy participants.
Researchers developed a new method to include uncertainty in predictive algorithms, ensuring accurate and reliable solutions. The approach uses Markov models to explicitly include uncertainty in specific parameters, allowing for faster predictions and more complete analysis.
The São Paulo School of Advanced Science on Emerging Pollutants will tackle the challenges of monitoring and regulation of emerging pollutants. Applications can be submitted until April 20, 2025.
Most older U.S. adults support Medicare covering weight management medications, particularly those with a BMI of 30 or greater. The survey also found that more than half of participants were interested in using these medications to manage their weight.
A new study found that exosomes from children with pediatric obstructive sleep apnea (OSA) disrupted blood-brain barrier integrity, leading to cognitive impairments. The research suggests a broader impact on barrier function and identifies potential biomarkers for OSA-related neurocognitive dysfunction.
Recent studies published in Behavioral Medicine and Alcohol explore the link between pain and substance use among emerging adults. Individuals with moderate to severe pain are more likely to start using cannabis over a four-year period, often taking it up earlier, and are also at higher risk of mixing it with alcohol.
Researchers have identified nitisinone as a medication that can suppress mosquito populations by making human blood toxic to them. The drug, used to treat rare genetic diseases, has been shown to be more effective than ivermectin in killing mosquitoes and has the potential to control malaria spread.
Florida Atlantic University's Hamming Quasi-Cyclic (HQC) algorithm has been selected by the National Institute of Standards and Technology (NIST) as part of its Post-Quantum Cryptography project. HQC is designed to withstand attacks from quantum computers, making it a 'post-quantum' cryptographic solution.
Recent studies by Regenstrief Institute and Indiana University School of Medicine found a sharp decline in colorectal cancer screening trends during the pandemic, followed by a rapid rebound. The impact was more pronounced on non-invasive testing, such as fecal immunochemical tests (FIT) and FIT/DNA tests, which declined but recovered ...
Researchers have elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune responses. PP2A deficiency impairs T cell effector functions, leading to reduced cytokine production and impaired antiviral responses.
A new reverse genetics system for African swine fever virus (ASFV) has been developed, enabling rapid vaccine development and research into the virus's biology. This technology can be adapted for other viruses, including lumpy skin disease, Zika, chikungunya, and Ebola viruses.
The study reveals that the non-breeding population plays a key regulatory role in the eagle population, stabilizing the breeding population and helping to expand it. The methodology provides robust estimates of demographic processes, allowing for more effective conservation strategies.
Combining PCSK9 inhibitors with anti-PD-1/PD-L1 treatment may improve antitumor effects. PCSK9 inhibition enhances antigen presentation, promoting T cell recognition and killing of tumor cells.
Researchers at North Carolina State University have developed a system that actively removes microplastics from water in a single cycle. The microcleaners, made from biodegradable materials, use the Marangoni effect to self-disperse and capture microplastics, which are then collected by skimming.
A recent study by Rosa Kindt found that participatory budgets and referendums can increase trust in democracy among citizens, particularly those with populist views. Right-wing populists who participated in these initiatives reported a positive experience, appreciating the opportunity to share their opinions with other citizens.
A new NIH study found that individuals who engaged in light- and moderate-to-vigorous-intensity daily physical activity had a lower risk of cancer than those who were more sedentary. The researchers also discovered that higher daily step count was associated with a reduced risk of cancer, regardless of the pace of steps.
The study used AI analysis on over 4,200 clinical reports to identify key factors in autism diagnosis. Criteria related to repetitive movements and special interests were strongly linked to an autism diagnosis, while socialization criteria were not highly specific.
A UK study found that children of obese mothers are more likely to become obese adults, suggesting that societal and early-life factors play a significant role in obesity. The study analyzed data from over 17,000 people born in the same week in 1958 and found that these early life factors persisted through adulthood.
Researchers at the University of Houston College of Pharmacy have identified a potential therapeutic target to repair injured muscles. They discovered that fibroblast growth factor–inducible 14 (Fn14) plays a crucial role in regulating satellite cell stability and function, which are responsible for muscle growth, repair, and regenerat...
Ochsner Health received the 2025 Gallup Exceptional Workplace Award for its innovative approach to employee development, fostering a culture of professional growth and innovation. The organization prioritizes engagement and provides resources, support, and inspiration to enable high-quality care.
A new study by UNLV researchers finds that diabetes weakens the anterior cingulate cortex, suppressing reward perception and memory signals, leading to mild cognitive impairment. The connection between high blood sugar levels and Alzheimer's disease may be linked to altered hippocampal theta synchrony.
Researchers have introduced Orion, a novel framework that brings fully homomorphic encryption to deep learning, enabling computations on encrypted data without decrypting it. The framework achieves a 2.38x speedup over existing state-of-the-art methods and enables high-resolution FHE object detection using large neural networks.
A new study found that deep-sea mining for rare metals has a persistent impact on biodiversity and species variety in the deep ocean. The research, conducted 5,000m below the surface in the Pacific Ocean, showed that even 44 years after the initial mining test, lower levels of biodiversity remain at the site.
A recent study found that a probiotic supplement called Lactobacillus helveticus CCFM1320 can improve sleep quality in patients with insomnia. The probiotic enhanced the methylation of N-acetylserotonin, leading to normalized circadian rhythm gene expression.
The ISS National Lab's new podcast, 'Between a Rocket & a Hard Space', offers exclusive insights from scientists, engineers, and visionaries on the future of space research. The first episode explores the groundbreaking science happening on the International Space Station, including its impact on medicine, technology, and industry.
Four Ochsner Health nurses have been named to the Louisiana State Nurses Association's 40 Under 40 list, recognizing their exceptional leadership qualities and commitment to the nursing profession. The recognition celebrates these nurse leaders who embody compassion and kindness, delivering high-quality care to patients and communities.
A large majority of older Americans believe health insurance – including Medicare – should cover anti-obesity medications. Nearly 37% of respondents met the criteria for overweight and 36% for obesity. Medicare currently covers a drug used for weight management but only in people with diabetes or a history of heart attack or stroke.
A team of researchers from JPMorganChase, Quantinuum, and the University of Texas at Austin have successfully demonstrated certified randomness using a 56-qubit quantum computer. This achievement has significant implications for cryptography, fairness, and privacy, as it enables the generation of truly random numbers that cannot be man...
Scientists at Tohoku University have successfully improved the phosphorescence efficiency of silver clusters by incorporating a heavy atom effect, which enhances intersystem crossing and leads to increased phosphorescence. This discovery provides a new design strategy for next-generation luminescent materials and triplet sensitizers.
Researchers at UT Health San Antonio have discovered a way to delay or even block recurrence of the deadliest brain cancer after radiation by targeting senescent cells with experimental 'senolytic' drugs. This approach shows promise in preventing tumor growth and improving patient survival.
Researchers at the University of Portsmouth have developed a smart insole system that accurately measures ground reaction forces, providing real-world movement analysis. The technology outperforms existing wearable technologies and has potential applications in sports performance, injury prevention, and healthcare monitoring.
The Idaho National Laboratory is seeking a private sector sponsor to invest in an innovation incubator supporting breakthrough innovations in nuclear energy, cybersecurity, and advanced materials. The program aims to provide seed-stage startups with access to INL's world-class facilities and technical expertise.
Researchers used large language models to analyze healthcare records of over 1,000 children with suspected autism, finding that current criteria prioritize socialization skills and not enough on interests and natural behaviors. The study suggests revising the criteria to focus more on repetitive behaviors and special interests.
The High Power Grid Lab will test new grid components and technologies under realistic conditions, focusing on low- and medium-voltage grids for regional power distribution. The lab aims to investigate system properties of innovative grid components in a grid environment that accurately replicates the real world.
A study by Eawag and the University of Zurich found that human impacts on biodiversity are widespread and severe, with average species declines of 20% across all biogeographic regions. The composition of species communities is also shifting, with environmental pollution and habitat changes having a particularly negative impact.
Scientists have long believed that cells respond to stress in a linear chain of events, but a new study reveals a more complex 'split-integrated stress response' that can be fine-tuned depending on the type and intensity of stress. This flexibility could lead to new targets for treating cancer and neurodegenerative diseases.
Torsten Hoefler's groundbreaking work on high-performance computing and AI has revolutionized the capabilities of supercomputers. His innovations include MPI-3 nonblocking collective operations, 3D parallelism, and routing protocols that power modern AI systems.
Researchers used a large language model to analyze clinical reports of autism patients and found that repetitive behaviors and special interests are most indicative of an autism diagnosis. The study aims to improve diagnostic guidelines by reducing the focus on social factors.
Researchers at Kyoto University have captured the first high-resolution structure of Ebola's nucleocapsid using single-particle cryo-electron microscopy. This visualization reveals sophisticated interactions between structural components, including VP24 and NP proteins, which govern virus assembly, RNA synthesis, and transport.
Researchers created an atlas of the brain's mitochondria, revealing that younger brain regions have more specialized mitochondria for efficient energy production. The study provides a new perspective on the role of energy in brain health and may lead to new approaches for treating neurological and psychiatric disorders.
A high-fat diet reduces neurotensin, a brain peptide that interacts with the dopamine network, leading to reduced pleasure in eating. Boosting neurotensin levels restores pleasure and promotes weight loss in mice, offering new avenues for addressing obesity.
In 2024, MDPI published 238,000 peer-reviewed open-access articles, tripling its research integrity team size. The publisher expanded its global workforce to 6,650 staff across 21 offices, publishing more than 25 million downloads of fully open-access research.
Researchers at the University of Bristol discovered that cuttlefish employ a novel form of motion camouflage by displaying dark stripes on their head and arms. This allows them to disguise their hunting movements and deceive their prey's visual system, overwhelming it with strong dynamic motion cues.
Researchers discovered that D1 and D2 neurons in the brain work together to process appetitive and aversive stimuli, with D2 neurons playing a key role in extinguishing negative associations. This understanding can help develop new treatments for anxiety and post-traumatic stress.
A study led by Evan Gora found that Dipteryx oleifera trees can survive direct lightning strikes with minor damage, while other trees are badly damaged. The researchers discovered that these trees tend to have fewer lianas and are more likely to gain an advantage in competing for light and space after being struck by lightning.
Researchers have identified a novel mechanism of intercellular communication involving mRNA transfer between different types of stem cells. This phenomenon enables cell fate conversion and reverts human pluripotent stem cells to an earlier embryonic stage.
The Chan Zuckerberg Initiative's CZ Biohub San Francisco and CZ Imaging Institute will join forces to develop novel imaging technologies that provide entirely new insights into human biology. This new Biohub aims to illuminate the dynamic architecture of living systems, making what was invisible visible, measurable and understandable.
Researchers evaluate traditional precipitation phase partitioning methods and machine learning models, revealing near-freezing temperatures create inherent limitations in distinguishing between rain and snow. Accurate identification is critical for weather forecasting, hydrologic modeling, and climate research.