A study revealed persistent disparities in cancer care for LGBTQ+ populations, particularly transgender individuals, who face significant challenges accessing breast and cervical cancer screenings. The research highlights the urgent need for targeted interventions to bridge these gaps and ensure equitable care.
Researchers from the University of Osaka found that antagonistic ties play a crucial role in shaping social maps in the brain, which are also reflected in patterns of brain activity. This study sheds light on how our brains organize complex relationships and rivalries.
The Super-Kamiokande observatory has detected an indication of the Diffuse Supernova Neutrino Background (DSNB), a flux of neutrinos from many different supernovae over time. This breakthrough achievement provides a crucial clue for understanding the history of cosmic star formation and nucleosynthesis.
A non-canonical mTOR–SGK1 pathway regulates neuronal necroptosis, and targeting this axis halts necroptosis and neuroinflammation in traumatic brain injury. S6K1 inhibitors alleviate trauma-induced neuroinflammation and functional deficits.
The research shows that meaningful emission reductions are possible in small-vessel decarbonization, but the best option depends on context. Electrification performs best on short, predictable routes with low-carbon electricity and adequate charging infrastructure.
A new study found that AI-generated lunar crater catalogs often perform poorly when evaluated using human-defined scientific standards. The research highlights the need for standardizing benchmarks and transparent reporting to ensure the accuracy of AI-generated data.
A new study found that BCG vaccines can modify Alzheimer's biomarkers in non-Alzheimer's participants, suggesting a potential biological explanation for the observed link between BCG vaccination and lower disease risk. The vaccine also promoted increased immune responses in healthy participants without Alzheimer's pathology.
Researchers introduced a new method to measure firm capabilities, creating a 'capabilities ladder' to identify basic and advanced capabilities. The study found significant nestedness within the ladder, with firms at lower rungs having basic managerial, production, and communication capabilities.
Researchers at The University of Osaka used AI to evaluate characterization frameworks for molecular order in liquid water. They found that machine learning models can accurately capture key structural information, shedding light on the relationship between structural fluctuations and thermodynamic states of water.
A study by Chiba University researchers confirms Gentiana squarrosa obtains carbon through both photosynthesis and fungal symbiosis. The U-shaped pot cultivation system developed for this study enables the verification of carbon transfer between plants via AM fungi in various plant species.
Researchers at Kyushu University developed a new food preservation solution using pumpkin peel, creating a nanomaterial that slows deterioration of fruit and reduce transport damage. The material showed good biocompatibility and was effective in suppressing microbial growth and preserving freshness.
Optoelectronic tweezers (OETs) manipulate single cells through dielectrophoretic forces, offering a unique approach to cell capture, transport, sorting, analysis, and functional screening. OET integrates with microfluidics and other technologies for label-free single-cell physical parameter measurement and biomolecule manipulation.
Researchers found that targeting PAK1 enhances therapeutic efficacy of PARP inhibitors in ovarian cancer by impairing DNA repair. Combining olaparib with IPA-3, a PAK1 inhibitor, results in increased tumor cell killing and DNA damage accumulation.
A new study led by Dr. Anthony Lapsansky and Dr. Doug Altshuler found that pigeons make slow, subtle eye movements during flight to gather more information about their surroundings. This research has implications for the development of autonomous flying robots or drones, which can learn from bird-like visual strategies.
Researchers have successfully produced genome-edited T cells that can target and destroy cancer cells using the Platinum TALEN genetic engineering technique. The technique was found to be efficient, with an average yield of 72 million 1G4-TCR cells for every 3 million T-cells.
A biomaterial scaffold has been developed to recreate a skull stem cell niche, reducing craniosynostosis-related deformities and promoting normal skull growth. The triphasic scaffold maintained skeletal stem cells while supporting bone formation and tissue regeneration.
A study identified a brain pattern related to the tau protein that changes according to the stage of Huntington’s disease. The discovery opens doors to new biomarkers and treatments for this rare, hereditary neurodegenerative disease.
New research reveals alpine butterflies closely match local warming in range shifts, but habitat availability drives community composition and climate change response. The study finds that butterfly communities have become warmer-adapted over the past two decades, with specialist species vulnerable to elevational hostplant mismatches.
Researchers analyzed the composition of interstellar comet 3I/ATLAS, revealing high carbon and nitrogen isotopic ratios indicative of an outer solar system origin. The findings suggest 3I/ATLAS may be over twice as old as the Sun, shedding light on the formation history of this ancient celestial body.
Insilico Medicine has expanded its generative AI capabilities through a strategic collaboration with Liquid AI, yielding models optimized for retrosynthesis and multi-omics target discovery. The company's platform upgrades enable enterprise-grade automation, parallel simulation, and precision sifting in biologics design.
Scientists have successfully created programmable supramolecular polymers in neutral lipid environments, such as triolein-rich lipid droplets. This breakthrough provides a new method for regulating cellular functions and has potential applications in treating diseases involving lipid droplets.
A new carbon nanotube bandage provides a practical, deployable alternative for shape sensing in robots used in surgery. The sensor can be easily installed and offers real-time intraoperative guidance.
The Korea University College of Medicine and UNIST have been selected for the Ministry of Health and Welfare's K-MediST program, aiming to establish a leading model for integrated education and research in medical science and technology. The partnership will create an innovative interdisciplinary hub bridging medicine and engineering.
A team of researchers has developed chimeric allergen receptors that can suppress the immune system's response to common allergens, reducing or preventing asthma symptoms in mice. The technique could eventually be used to treat a wide variety of allergies in humans.
A study on coyote attacks in Stanley Park revealed that habituation and food conditioning contribute to aggressive behavior. To coexist with coyotes, people should not feed them, avoid approaching them, and be aware of their presence during certain times and locations.
Researchers uncover a previously unknown phase transformation mechanism in monolayer molybdenum telluride (MoTe2) that is fundamentally distinct from the conventional martensitic model. The study reveals a one-dimensional 'domino-like' chain reaction that triggers structural rearrangement and enables programmable electronic devices.
The Vaccine Innovation Center will develop a next-generation mRNA-based hantavirus vaccine using proprietary domestic technologies, leveraging self-amplifying mRNA and lipid nanoparticle delivery systems. Preclinical studies have demonstrated strong immunogenicity and protective effects.
A team of scientists has discovered 31 of the most ancient quasars ever found, including two that radiated light from a trillion suns when the universe was just 670 million years old. These findings provide crucial clues for understanding how supermassive black holes formed and offer insights into the early universe's structure.
The study found that primary care clinicians can make a significant impact on diabetes management by initiating continuous glucose monitoring, leading to improved glycemic control and reduced acute care utilization. This scalable strategy has the potential to improve diabetes outcomes in underserved populations.
A five-year study will focus on developing and evaluating compounds to treat best vitelliform macular dystrophy, a rare inherited retinal disease affecting the retina. The research aims to improve patients' lives by preserving sight.
Researchers found that frequency-specific transcranial photobiomodulation elicits complementary glial mechanisms for neurovascular protection and amyloid clearance in Alzheimer's disease. CW light primarily targeted astrocytes, while 40-Hz light drove microglial clustering around Aβ plaques.
A recent study published in Cancer Epidemiology, Biomarkers & Prevention found that men were more likely to be diagnosed with regional and distant stages of 20 nonreproductive solid cancer types in the United States. Men were significantly more likely than women to be diagnosed with regional tongue cancer, salivary gland cancer, oropha...
A new learning-based adaptive tuning method integrates chaotic search with particle swarm optimization to improve stability and solution quality in chaotic search algorithms. The approach consistently achieves better results than conventional methods, providing a practical means of enhancing the performance of chaotic search.
The new institute aims to accelerate data-driven health care with partnerships between six schools, UC San Diego Health, and specialized centers. By integrating digital technology and rigorous research, the institute seeks to achieve scalable, reliable health outcomes for all.
The University of Cambridge will join the Yang Tan Collective with Harvard University and MIT to focus on cutting-edge science and accelerate autism research. Research centers will investigate challenges faced by autistic individuals, including lower life-expectancy rates and early diagnosis.
A large-scale study of an online patient portal shows that AI-generated responses can introduce errors and extraneous details, leading to increased editing time for physicians. Adapting AI to individual physician communication styles can improve accuracy by 33% and reduce editing by 26%.
The European Space Agency's Euclid space telescope has discovered 31 of the oldest quasars ever found, revealing insights into the universe's first 670 million years. The two most ancient quasars have redshifts of 7.77 and 7.69, setting a new record for their age.
Women who experience violence are more likely to reach the menopause earlier and exhibit severe hot flushes, anxiety, and depression. Trauma also exacerbates systemic health issues such as hypertension, diabetes, and bone loss, creating a 'hidden burden' of morbidity.
Dimensions Research Strategy is an AI analytics platform that provides evidence-backed strategic briefs based on the world's most interconnected research data. The platform aims to support university leadership in benchmarking and expertise, offering verifiable intelligence for informed decision-making.
A secret shopper study found that online prescription vendors for GLP-1 receptor agonists often lack clinician interaction, relying on patient-reported questionnaires. This may lead to prescriptions being issued without important clinical and social history, compromising patient safety.
A new policy brief from PollinERA proposes a regional pesticide budget system to manage total pesticide pressure at landscape scale. The system would align with EU environmental law and provide farmers with a practical incentive to choose lower-impact products.
A newly published paper reveals that Karenia cristata, the source of neurotoxins in a devastating South Australian algal bloom, is the most toxic species ever studied. The bloom caused mass mortality of marine animals and has taken an immense environmental toll on the region.
A study by Professor Masaki Yoshida suggests that there is a physically meaningful upper limit to viscosity beyond which materials effectively become rigid. The research found that the maximum viscosity inferred from stable lithospheric regions is around 10^30 Pa s, making it roughly 10^33 times greater than water's viscosity.
Researchers propose a new framework, BOC, inspired by biological nervous systems to build more adaptive intelligent systems. The framework integrates sensing, memory, and computation directly at the hardware level, reducing data movement and latency.
Researchers developed an on-chip all-optical supernode for ultra-low-latency deep neural network inference, achieving a 100-fold increase in inference speed while using only one-ninth of computing resources. The system supports high-speed data routing and switching with low loss and flat response over a spectral range exceeding 100 nm.
A new study reveals that large language models can systematically alter the direction of users' messages on contested topics, even when instructed to preserve the original meaning. The researchers show how these small changes can accumulate and gradually influence broader public opinion over time.
A major new study suggests that age-related changes in the uterus may contribute to poorer pregnancy outcomes, with women aged 49 and over experiencing lower live birth rates and higher miscarriage risk despite donor-oocyte treatment. The study found that cumulative live birth rates declined substantially with age, from 80% among women...
A study has developed an integrated process to produce dissolving pulp from sugarcane bagasse using a carbonate-based oxygen-alkali pulping combined with enzymatic totally chlorine-free bleaching. The process resulted in high-quality pulp with improved properties, meeting industrial requirements.
A new study highlights the annual AU$7 trillion value of nature in mental health benefits and calls for urgent government action to expand access to nature as a frontline response to the worsening global mental health crisis. Regular, intentional exposure to natural environments is proposed as a proven yet underused solution to improvi...
A new method called DD-r²SCANH addresses the problem of underestimating band gaps in narrow-gap semiconductors. It combines two mathematical tools, r²SCAN and a smart algorithm, to predict dielectric constants more accurately.
Researchers from CityUHK successfully recycle spin-triplet excitons, increasing power conversion efficiency in organic photovoltaics to 20.5%. By fine-tuning the side-chain structure and exciton delocalisation, they facilitate the dissociation of triplet excitons, paving the way for next-generation high-performance organic solar cells.
Scientists at SUSTech and collaborators report first experimental observation of one-sided chiral hinge states in a 3D magnetic Weyl photonic crystal, verifying the 3D QHE of Fermi arcs. The discovery reveals a new physical mechanism for robust light transport in 3D space with potential applications in topological photonic devices.
A Chinese research team found that environmental allergens activate gasdermin D through an iron-dependent mechanism, promoting IL-33 release and allergic airway inflammation. This iron-GSDMD-IL-33 axis is a potential driver of type 2 immune responses in asthma.
Researchers at RMIT University have developed a new method for removing microplastics from wastewater, achieving removal rates of more than 90% through the use of microbubbles and nanobubbles. The approach is simple to implement and significantly increases plastic removal during primary treatment.
Research suggests that speaking more than one language can delay brain ageing and make individuals appear younger. The study found that those who spoke two languages had brains that appeared around six years younger, while those who spoke four languages appeared up to 13 years younger.
A new global certification program and recommendations have been developed to advance stroke rehabilitation globally. The program aims to improve access to stroke rehabilitation, particularly in low-and-middle-income countries.
Researchers at NUS have developed a new method called qChIP-MS to identify groups of proteins that work together at specific locations on DNA. This technique allows scientists to better understand how DNA is organised and regulated inside our cells, which could lead to breakthroughs in cancer biology and genome regulation.
Researchers found that dietary fat balance influences T-cell membrane oxidation, making them more vulnerable to ferroptosis. This can weaken immune responses, including CAR-T cell therapy effectiveness.
Researchers examine the flow physics and modeling challenges governing EUV sources, highlighting the importance of debris control and multiscale fluid dynamics. The study aims to provide a common framework for laser-plasma and fluid mechanics communities, supporting future advances in EUV source performance.
Researchers used solar radiation to enhance hydrochar, a carbon-rich material derived from biomass, to create a more effective soil amendment. The study found that aged hydrochars delivered impressive results, increasing soil organic carbon content by up to 110% and enhancing beneficial microbial taxa.