Researchers at CU Anschutz have developed a promising nonhormonal therapy for women experiencing Genitourinary Syndrome of Menopause (GSM), which affects the vulva, vagina, and urinary tract. The therapy restores estrogen signaling in vaginal tissue without exposing the rest of the body to estrogen.
Scientists developed a device that controls heat radiation direction and switches this effect on and off, enabling 'heat programming' like microchip data. The new material exhibits different responses depending on light direction, improving efficiency compared to previous devices.
The department has demonstrated outstanding clinical proficiency in robotic-assisted procedures and has been at the forefront of education and technical exchange. It plans to further expand training programs and integrate digital capabilities into clinical practice.
A new study found that clinician support significantly increases patient adoption of virtual reality therapies, leading to better time-based adherence and technology acceptance. The research team evaluated three implementation environments, with provider-led support demonstrating the most favorable usability pattern.
Researchers emphasize the importance of enhancing visual intelligence in autonomous robots to achieve complex tasks. Visual perception, decision-making, path planning, and control must be integrated for robots to perform reliably. The ultimate goal is to make robots have human-like intelligence and enable collaboration between robots.
The gut microbiome is recognized as a key driver of tumor initiation and progression, with microbial dysbiosis fueling malignancy or enhancing anti-tumor immunity. Microbiome science and cancer biology are converging to develop new strategies for prevention, diagnosis, and therapy.
A new gene circuit technology has enabled cells to autonomously generate programmed responses, processing multiple molecular signals at once. The RATEX platform allows cells to compute and respond to various types of molecular information.
A team of food scientists found that non-alcoholic beer can be made safer with moderate carbonation, low pH and hops. The most robust protection came from a combination of these factors, which was able to control the growth of five common foodborne pathogens.
Darwin's Ark has established the world's largest community-powered pet research initiative, combining genetic data with owner information to explore questions about pet health, behavior, ancestry, and evolution. Researchers can collaborate by submitting a request form, accelerating discoveries that benefit animal and human health.
Researchers at Scripps Research Institute have made progress toward a long-sought vaccine capable of broad protection against HIV. The new approach, called germline-targeting sequential immunization, guides precursor B cells to produce broadly neutralizing antibodies that can recognize and block many different HIV strains.
Researchers proposed a hybrid frequency-dimension simulator to explore complex lattice models, achieving scalable programmability and operation stability. The simulator's ability to introduce asymmetric couplings enables the simulation of diverse topological phases.
A new method combining FTIR spectroscopy with machine learning improves gas concentration estimation in complex industrial conditions.
Researchers developed an all-soft robotic system utilizing liquid crystal holography for optical command processing, achieving a synergy of multi-degree-of-freedom actuation and information multiplexing. The system showcases an intelligent gripper capable of precise grasping and object classification.
A study from Huazhong Agricultural University sheds light on the intricate processes of microbial activity and geological structures beneath our feet. The team's work illustrates how bacterial EPS contributes to SOM persistence, a process crucial for maintaining soil health and securing long-term carbon storage.
Researchers stabilize B31-type MnSe0.5Te0.5 phase with superconductivity driven by pressure-induced Jahn-Teller distortions. The team's chemical strategy enables the emergence of superconductivity at lower pressures.
A new University of Arizona study reveals that more than 70% of parents and children in the US use media across various devices during family meals. The study found that media use by parents and children is not linked to each other, and that ethnicity is a significant predictor of media use.
A new study published in Environmental and Biogeochemical Processes shows that changing soil water levels can disrupt the balance between two key steps of nitrification, a central process in the soil nitrogen cycle. Soil moisture and nitrogen availability jointly control the microbial 'handoff' in agricultural soil nitrogen cycling.
Researchers developed an AI platform, CANVAS, to predict cellular neighborhoods and their relationships in tumor tissues. The platform identified 10 discrete neighborhoods, including those rich in immune cells and associated with poorer outcomes and reduced responsiveness to immunotherapy.
A recent study found that spinner dolphins off Hawaii Island have alarmingly low calf numbers, indicating potential threats to their long-term survival. The researchers used drone-based photogrammetry and age-length data to determine the age structure of the population, revealing a stark contrast to expected healthy numbers.
Researchers successfully isolated highly pure geometric isomers of phytoene and phytofluene, revealing distinct ultraviolet absorption characteristics and different responses to light- and heat-induced isomerization. The study demonstrated strong UV-A-shielding capacity and antioxidant activity for these colorless carotenoids.
The e-BOCCHI program, developed to address adolescent loneliness, showed statistically significant reductions in depressive symptoms. Participants demonstrated improvements in help-seeking skills compared to baseline, but modest improvements in loneliness and self-esteem scores.
A new framework, coined as the 'belief effect', proposes that beliefs are shaped by factors such as a person's previous experiences and expectations, practitioner communication, treatment itself, and environment. This framework could help clinicians improve patient care by being more intentional about shaping belief.
A new approach embeds fundamental physical laws into neural networks, enabling detection of GNSS spoofing with high accuracy. The framework outperforms standard models on unseen attack scenarios, offering a blueprint for building AI-based security systems that anchor decisions in physical invariants.
Researchers used high-resolution topographic data to investigate landslide mechanisms. They found that soil thickness varies systematically with slope gradient, controlling depth and size of landslides. This study offers a foundation for hazard maps and risk assessments under climate change.
Researchers have developed a microfluidic platform that recreates the complex ecosystem surrounding pancreatic tumors and observed how cells interact dynamically. The findings reveal a critical mechanism that may explain why many therapies fail and point to new therapeutic strategies.
A miniaturized spectroradiometer based on VIPA technology achieves high spectral resolution for atmospheric water vapor profiling. The system enables researchers to visualize water vapor distribution across the atmosphere, layer by layer.
A research team at Hefei Institutes of Physical Science, Chinese Academy of Sciences, has realized a superconducting diode effect that preserves time-reversal symmetry in NbSe2 homojunctions. The device was built using a solid-state proton gating technique to form n–n, p–n and p–p junctions, all operating under zero magnetic field.
Researchers at the University of Osaka have developed a safe and sustainable sequential process for preparing Davis reagents using sunlight and molecular oxygen. The method produces meta-chloroperbenzoic acid (mCPBA) only as needed, greatly reducing risks associated with storing or handling bulk peracids.
The study reviews SLM optimization strategies and evaluates a Greek labor-law assistant that combines fine-tuning, Retrieval-Augmented Generation and quantization for practical local deployment. The evaluation used standard language-generation and retrieval-oriented metrics, indicating that larger models achieved stronger scores while ...
A research team at Pohang University of Science & Technology has developed a next-generation semiconductor with enhanced performance and stability. The breakthrough solution, called 'Volatile Surface Reconstruction,' converts unreacted tin ions into a volatile compound that volatilizes, while creating a self-protective layer to shield ...
A new editorial highlights AI's role in scientific discovery, proposing a framework to evaluate AI-enabled scholarship. The authors emphasize the need for transparency, reproducibility, and real-world value in AI-driven research.
A randomized clinical trial found that long-acting analogue insulin glargine was associated with less time spent in dangerous hypoglycemia and fewer nighttime low blood sugar events. However, benefits only emerged after a year into the trial.
Researchers have discovered a link between endometriosis and unique hormone patterns, which could lead to a simple, non-invasive diagnostic blood test. The study found that individuals with endometriosis exhibit distinct levels of androgens, including testosterone, in their blood.
A large European study found a correlation between ultra-processed food consumption and increased levels of harmful fatty acids in the blood. The study, which analyzed data from 15,200 participants, suggests that ultra-processed foods may contribute to metabolic stress and potential health risks.
A large study suggests exposure to air pollution during sperm development can impact genes associated with sperm development, chromosomal organisation and cellular quality control. Researchers identified 39 DNA methylation changes linked to air pollution mixtures, including ozone and nitrogen dioxide.
A landmark international study found that halving patient out-of-pocket costs for fertility treatment significantly increased births achieved through ART, with a 2.67-fold increase reported. Countries with lower cost-to-baby metrics consistently achieved higher levels of ART utilisation, highlighting the importance of affordability in ...
A KAIST research team developed a foundational technology for 'temperature-based DNA synthesis,' synthesizing desired DNA using only temperature. The team also demonstrated a 'DNA temperature black box' that records temperature changes during shipping without electricity.
Scientists found that hummingbirds facilitate the creation of new species in bromeliad plants at a rate of 2.77 per million years, compared to 1.46 for other pollinators. This accelerated evolution is attributed to hummingbirds' high-altitude feeding habits and their ability to act as an engine for new species.
According to the European IVF Monitoring Consortium, over 1.15 million fertility treatment cycles were reported across Europe in 2023, resulting in the birth of 247,021 children. The growth in frozen embryo transfer (FET) was particularly notable, with FET cycles increasing by 151% compared to previous years.
A nationwide study found substantial regional differences in sperm quality, with men in northern Spain recording the strongest semen quality. Lifestyle habits were broadly similar across regions, suggesting environmental exposures may play a role in male reproductive health.
Researchers found that a single exposure to cocaine can alter the structure of mouse brain cells, leading to lasting changes in gene expression and neural function. These persistent changes may increase the risk of addiction and raise questions about the potential long-term effects of recreational cocaine use.
A decade-long study found that benzodiazepine prescribing declined steadily before 2020 but leveled off after the pandemic began. Adults aged 75+ and those receiving medications through long-term care pharmacies saw an increase in prescriptions, highlighting the need for medication safety efforts.
A new study found that bacteria in contaminated brick kiln soils reorganize their communities, strengthen stress-response functions, and activate detoxification genes. This understanding can help design more effective microbial restoration strategies for industrial sites.
Research at Columbia University Irving Medical Center found that people who got 5-6 hours of sleep a night gained an average of one pound over six weeks, with increased sedentary time. This study suggests that getting adequate sleep may help reduce the risk of weight gain and obesity-related conditions.
Researchers at Michigan State University found that current AI models can be duped into seeing signatures of life in digital organisms with high accuracy. However, when tested on unseen examples, the results were less impressive. The team showed that it was possible to convince the AI that it was seeing signs of life where they didn’t ...
A new study found that women taking hormone-containing birth control pills experienced higher rates of binge-related eating compared to those taking hormone-free pills. The research, published in JAMA Network Open, suggests that the hormones in birth control pills may contribute to increased emotional eating.
A pooled analysis of two randomized trials found that decreasing sleep by just 1.5 hours each night was associated with increases in body weight, waist circumference, and sedentary time in adults with elevated cardiometabolic risk. The findings highlight the importance of discussing sleep duration at health care visits.
A study found that rock glaciers in the Teton Range persist ice longer than exposed glaciers and snowfields due to insulation from debris. This provides a sustained cold-water streamflow, contrasting with rapid melting of exposed ice glaciers and snowfields.
A team of U of A astronomers helped an international research consortium discover the faintest and farthest quasars in the early universe, revealing new insights into supermassive black holes and their host galaxies. The discovery includes two record-breaking quasars with cosmic ages of about 670 million years.
A new study suggests that early humans in North and South America relied heavily on hunting large mammals, such as mammoths and giant ground sloths, for food and sustenance. The researchers estimate that at least 98% of their diet came from these large animals.
Researchers applied bioenergetic approach to evaluate competing theories about Hannibal's crossing, focusing on war elephants' energy demands. The study supports the Col de la Traversette as the more likely route, with an estimated energy cost of 5.42 TJ for the whole army.
Researchers have identified a promising drug to treat neurodegenerative conditions, including Alzheimer's disease and traumatic brain injury. The study found that inhibition of an enzyme called 15-PGDH was potently neuroprotective by restraining the production of reactive oxygen species that damage the brain.
The iMETRO Dynamic Simulation is an open-source platform that enables researchers to develop and test robotic systems for future space missions. By leveraging a digital twin of the NASA iMETRO facility, scientists can remotely create and test new robotic software and validate its performance with various hardware configurations.
A team of researchers has developed a new method for finding effective tuberculosis drugs by leveraging the PAC-MAN technique and artificial intelligence. The approach uses machine learning models to predict which chemical compounds can penetrate the outer membrane of the bacteria, paving the way for more efficient drug discovery.
A new PNAS special feature showcases the critical role of behavioral and decision sciences in U.S. governance, highlighting how psychological and economic research protect public health, consumer rights, and finances across federal agencies. The research demonstrates how 'invisible' scientific frameworks streamline medical drug reviews...
Climate-related damages could further weaken Italy's already fragile economic growth and worsen debt sustainability, with potential losses of up to 15% by the end of the century. The study highlights the need for mitigation and adaptation measures to protect economic growth and financial stability.
Researchers identified 17 additional regions of the brain that appear to play a role in language, including parts of the cerebellum and hippocampus. These regions make up about 5 percent of the total volume of the adult brain and contribute to language processing despite being distant from traditional language centers.
A study published in Proceedings of the National Academy of Sciences found that bumblebees display observable 'liking and disliking' behaviours after consuming different liquids. This suggests that insects can evaluate tastes as pleasant or unpleasant, pushing the understanding of their inner life.
Ochsner MD Anderson Cancer Center has earned two accreditations from the American College of Surgeons (ACS) Commission on Cancer and National Accreditation Program for Breast Centers. The center's multidisciplinary approach brings together specialists in cancer disciplines to support patients with complex needs. Additionally, Ochsner M...
Researchers will study blood samples and environmental exposures over 10 years to identify genetic, environmental, and cellular factors contributing to autoimmune diseases. The goal is to develop prevention strategies and treatments by understanding the earliest biological triggers of SARDs.